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  1. Article ; Online: Association Between Recurrent Preeclampsia and Attendance at the Blood Pressure Monitoring Appointment After Birth.

    Saffian, Eleanor / Palatnik, Anna

    Journal of obstetric, gynecologic, and neonatal nursing : JOGNN

    2023  Volume 53, Issue 2, Page(s) 132–139

    Abstract: Objective: To examine the association between recurrent preeclampsia and attendance at the standard of care blood pressure monitoring appointment after birth.: Design: Retrospective cohort.: Setting: Single Magnet-accredited hospital affiliated ... ...

    Abstract Objective: To examine the association between recurrent preeclampsia and attendance at the standard of care blood pressure monitoring appointment after birth.
    Design: Retrospective cohort.
    Setting: Single Magnet-accredited hospital affiliated with an academic medical center.
    Participants: Multiparous women who gave birth between 2010 and 2020 and were diagnosed with preeclampsia (N = 313).
    Methods: We divided participants into two groups: those with prior preeclampsia (n = 119) and those without prior preeclampsia (n = 194). Using logistic regression, we calculated unadjusted and adjusted odds ratios to estimate the association between attendance at the postpartum blood pressure (PPBP) monitoring appointment and prior preeclampsia. We also explored the relationship between attendance at the PPBP monitoring appointment and use of magnesium sulfate during labor and birth and the relationship between attendance at the PPBP monitoring appointment and use of maintenance antihypertensive medications.
    Results: In adjusted analysis, participants with prior preeclampsia were 66.4% less likely to attend the PPBP monitoring appointment compared with those without prior preeclampsia, adjusted OR = 0.34, 95% CI [0.18, 0.62]. Administration of magnesium sulfate during delivery admission and use of maintenance antihypertensive medications were not associated with a change in attendance at the PPBP appointment.
    Conclusion: Further research on patient-perceived risk of recurrent preeclampsia and improvement of systems to facilitate postpartum follow-up is needed.
    MeSH term(s) Pregnancy ; Female ; Humans ; Pre-Eclampsia/diagnosis ; Magnesium Sulfate/therapeutic use ; Retrospective Studies ; Blood Pressure ; Antihypertensive Agents/therapeutic use
    Chemical Substances Magnesium Sulfate (7487-88-9) ; Antihypertensive Agents
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193135-0
    ISSN 1552-6909 ; 0884-2175 ; 0090-0311
    ISSN (online) 1552-6909
    ISSN 0884-2175 ; 0090-0311
    DOI 10.1016/j.jogn.2023.11.002
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  2. Article ; Online: Prospective Survey of Discrimination in Pregnant Persons and Correlation with Unplanned Healthcare Utilization.

    Greenberg, Rachel / Anguzu, Ronald / Jaeke, Elisha / Palatnik, Anna

    Journal of racial and ethnic health disparities

    2023  

    Abstract: Objective: To determine the association between lifetime exposure to discrimination and unplanned healthcare utilization in pregnant persons.: Methods: This was a prospective cohort study of pregnant persons receiving care from 2021 to 2022. Primary ... ...

    Abstract Objective: To determine the association between lifetime exposure to discrimination and unplanned healthcare utilization in pregnant persons.
    Methods: This was a prospective cohort study of pregnant persons receiving care from 2021 to 2022. Primary data was collected from participants on sociodemographic factors and on Perceived Ethnic Discrimination Questionnaire (PED-Q), a validated 17-item scale measuring perceived lifetime interpersonal racial and ethnic discrimination in four domains: work/school, social exclusion, stigmatization, and threat. The primary outcome was unplanned healthcare utilization, defined as unplanned labor and delivery admissions, triage, Emergency Department, or urgent care visits. Bivariate and multivariate analyses were done to examine the association between lifetime exposure to discrimination and unplanned healthcare utilization.
    Results: A total of 289 completed the PED-Q and were included in the analysis. Of these, 123 (42.6%) had unplanned healthcare utilization. Mean (SD) of lifetime racial and ethnic discrimination was significantly higher in people with unplanned healthcare utilization compared to those with planned healthcare utilization [1.67 (0.63) vs 1.48 (0.45), p = 0.003]. Univariate analysis showed that lifetime racial and ethnic discrimination was significantly associated with unplanned healthcare utilization (OR 1.96, 95% CI 0.23-3.11). Significant associations were found between unplanned healthcare utilization and maternal age (p = 0.04), insurance type (p = 0.01), married status (p < 0.001), education (p = 0.013), household income (p = 0.001), and chronic hypertension (p = 0.004). After controlling for potential confounding factors, self-reported lifetime racial and ethnic discrimination remained significantly associated with higher odds of unplanned healthcare utilization (aOR 1.78, CI 95% 1.01-3.11).
    Conclusion: We found that a higher level of self-reported lifetime racial and ethnic discrimination was associated with increased unplanned healthcare utilization during pregnancy.
    Language English
    Publishing date 2023-09-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2760524-3
    ISSN 2196-8837 ; 2197-3792
    ISSN (online) 2196-8837
    ISSN 2197-3792
    DOI 10.1007/s40615-023-01789-x
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  3. Article ; Online: Effects of physical activity on placental analytes in nulliparous persons.

    Whorton, Allison E / Pan, Amy Y / Palatnik, Anna

    European journal of obstetrics, gynecology, and reproductive biology

    2023  Volume 292, Page(s) 158–162

    Abstract: Introduction: Physical activity during pregnancy has long been investigated for its role in preeclampsia prevention. The mechanism of this relationship is unknown, although some studies suggest physical activity may affect placental analytes throughout ... ...

    Abstract Introduction: Physical activity during pregnancy has long been investigated for its role in preeclampsia prevention. The mechanism of this relationship is unknown, although some studies suggest physical activity may affect placental analytes throughout pregnancy. The objective of this study was to determine the effect of physical activity on preeclampsia-associated placental analytes using a prospective cohort of pregnant nulliparous patients.
    Methods: This was a secondary analysis of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be. Frequency and duration of up to three leisure activities was reported in the first and second trimesters and was analyzed, with participants either meeting or not meeting the recommended exercise of 150 min per week. Levels of the following placental analytes, placental growth factor, soluble endoglin, and soluble fms-like tyrosine kinase-1 (sFLT1), were analyzed stratified by the physical activity level.
    Results: A total of 1,956 participants were included in the analysis. The level of sFLT1 in the first trimester was lower in the group that had ≥ 150 min per week of physical activity, compared to the group that had < 150 min (846.3 [821.6, 871,8] versus 893.0 [864.5,922.5], p = 0.017). There were no significant sFLT1 changes in the second trimester based on physical activity. After controlling for maternal demographic and clinical factors, sFLT1 levels in the second trimester were significantly lower (p = 0.049) in participants that had ≥ 150 min of physical activity per week.
    Discussion: Our findings of decreased sFLT1 levels suggest this could be the mechanism explaining the association between PA in pregnancy and lower risk of preeclampsia.
    MeSH term(s) Pregnancy ; Female ; Humans ; Placenta Growth Factor ; Placenta ; Vascular Endothelial Growth Factor Receptor-1 ; Pre-Eclampsia ; Prospective Studies ; Pregnancy Outcome ; Vascular Endothelial Growth Factor A ; Biomarkers
    Chemical Substances Placenta Growth Factor (144589-93-5) ; FLT1 protein, human (EC 2.7.10.1) ; Vascular Endothelial Growth Factor Receptor-1 (EC 2.7.10.1) ; Vascular Endothelial Growth Factor A ; Biomarkers
    Language English
    Publishing date 2023-11-15
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2023.11.018
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  4. Article ; Online: Attitudes and Beliefs Associated With COVID-19 Vaccination During Pregnancy.

    Cui, Yiwen / Binger, Kole / Palatnik, Anna

    JAMA network open

    2022  Volume 5, Issue 4, Page(s) e227430

    MeSH term(s) Attitude ; COVID-19/prevention & control ; COVID-19 Vaccines/therapeutic use ; Female ; Humans ; Intention ; Pregnancy ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-04-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2022.7430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Strategies to reduce COVID-19 vaccine hesitancy among pregnant individuals: Data from a prospective survey of unvaccinated pregnant women.

    Binger, Kole / Cui, Yiwen / Kelly, Jeffrey A / Palatnik, Anna

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2023  Volume 162, Issue 1, Page(s) 95–104

    Abstract: Objective: To explore strategies that could reduce coronavirus disease 2019 (COVID-19) vaccine hesitancy in pregnancy.: Methods: In 2021, the authors conducted a survey of pregnant women assessing attitudes and beliefs regarding COVID-19 vaccination. ...

    Abstract Objective: To explore strategies that could reduce coronavirus disease 2019 (COVID-19) vaccine hesitancy in pregnancy.
    Methods: In 2021, the authors conducted a survey of pregnant women assessing attitudes and beliefs regarding COVID-19 vaccination. The present analysis reviewed trusted sources of information about COVID-19 vaccination that could reduce vaccine hesitancy among pregnant respondents.
    Results: A total of 295 surveys were analyzed. Using 10-point Likert scales, intentions to accept COVID-19 vaccine were split between individuals with low (n = 126, 43%) and high (n = 141, 48%) intentions to receive the vaccine, with only a small percentage of women having midrange vaccination intentions (n = 28, 10%). When asked what would reduce their COVID-19 vaccine concerns, published data was the leading answer in both low (46.2%) and medium (35.7%) intention groups followed by personally knowing someone who got vaccinated during pregnancy (21.0% and 28.6% for low and medium groups, respectively). In contrast, an obstetrician's recommendation was the most common answer in the group with high intention to vaccinate (37.2%). Knowing someone who received the vaccine in pregnancy was the leading response for reducing concerns of COVID-19 vaccination among Black respondents.
    Conclusion: The survey identified several innovative and culturally specific approaches to address vaccine confidence and complacency and improve vaccine uptake in pregnant people.
    MeSH term(s) Pregnancy ; Female ; Humans ; COVID-19 Vaccines ; COVID-19/prevention & control ; Pregnant Women ; Prospective Studies ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.14799
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  6. Article ; Online: Models of determinants of COVID-19 vaccine hesitancy in non-pregnant and pregnant population: Review of current literature".

    Tostrud, Lauren / Thelen, Julia / Palatnik, Anna

    Human vaccines & immunotherapeutics

    2022  Volume 18, Issue 6, Page(s) 2138047

    Abstract: Vaccination has proven to be the most effective tool in controlling the COVID-19 pandemic. While pregnant individuals are considered to be a high-risk population and are more likely to experience adverse effects from COVID-19, vaccination rates among ... ...

    Abstract Vaccination has proven to be the most effective tool in controlling the COVID-19 pandemic. While pregnant individuals are considered to be a high-risk population and are more likely to experience adverse effects from COVID-19, vaccination rates among pregnant individuals are significantly lower than in the general population. The Health Belief Model (HBM), Theory of Planned Behavior (TPB), 3C model, 5C model, and 5A model have been used to assess vaccination hesitancy behaviors. In this paper, we review the use of each of these models to address vaccine hesitancy, with a focus on the pregnant population and the COVID-19 vaccine. The HBM, TPB, 3C model, and 5C model have demonstrated great versatility in their ability to evaluate, explain, and modify vaccine hesitancy and behavior. Up to date, the HBM and 3C models appear to be the most effective models to study and address vaccination hesitancy within the pregnant persons.
    Language English
    Publishing date 2022-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2022.2138047
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  7. Article ; Online: Patient-reported barriers and facilitators for intermittent pneumatic compression device use on the antepartum unit.

    Reinhard, Megan / Flynn, Kathryn E / Palatnik, Anna

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

    2022  , Page(s) 1–7

    Abstract: Objective: To examine patient barriers to intermittent pneumatic compression (IPC) device compliance during antepartum hospital admissions.: Methods: This was a prospective survey study of a diverse group of pregnant patients who were admitted to the ...

    Abstract Objective: To examine patient barriers to intermittent pneumatic compression (IPC) device compliance during antepartum hospital admissions.
    Methods: This was a prospective survey study of a diverse group of pregnant patients who were admitted to the antepartum floor in a quaternary care hospital from June 2019 through March 2021. Patients receiving pharmacotherapy for venous thromboembolism prophylactic or therapeutic indications were excluded. The primary outcome was patient reported barriers to use of IPC during antepartum hospital admission. Responses were summarized using descriptive statistics.
    Results: A total of 40 patients were surveyed. All participants correctly identified the purpose of IPC. When asked regarding IPC importance, 7.5% reported not important, 40% reported somewhat important but not a priority, 5% important only on the first day they were given, and 47.5% reported important whenever the patient was in bed. The most bothersome characteristics of IPC use identified by the respondents on a Likert scale from 1 to 5 were sweating, made the legs too hot, restricted movement, and inconvenience and time spent putting on and taking off the IPC. Making the device wireless/cordless (77.5%), using a lighter weight or cooler material for the cuffs (55%), and better availability of nurses to assist with putting on, taking off, and troubleshooting the IPC (17.5%) were identified by patients as ways to increase compliance with IPC.
    Conclusions: This survey identified several modifiable barriers to the use of IPC on the antepartum floor.
    Language English
    Publishing date 2022-10-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077261-0
    ISSN 1476-4954 ; 1057-0802 ; 1476-7058
    ISSN (online) 1476-4954
    ISSN 1057-0802 ; 1476-7058
    DOI 10.1080/14767058.2022.2128655
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  8. Article ; Online: Racial and Ethnic Disparities in Maternal and Neonatal Outcomes among Women with Chronic Hypertension.

    Stearns, Kristen / Tsaih, Shirng-Wern / Palatnik, Anna

    American journal of perinatology

    2022  Volume 39, Issue 10, Page(s) 1033–1041

    Abstract: Objective: The objective of this study was to compare maternal and neonatal outcomes in women with chronic hypertension by maternal race and ethnicity.: Methods: A retrospective cohort study of women with chronic hypertension was performed from the ... ...

    Abstract Objective: The objective of this study was to compare maternal and neonatal outcomes in women with chronic hypertension by maternal race and ethnicity.
    Methods: A retrospective cohort study of women with chronic hypertension was performed from the Consortium on Safe Labor (2002-2008). Maternal self-reported race and ethnicity were analyzed as non-Hispanic White, non-Hispanic Black, and Hispanic. Maternal outcomes included cesarean birth, postpartum hemorrhage, blood transfusion, placental abruption, eclampsia, maternal intensive care unit admission, and death. Neonatal outcomes included preterm birth (PTB), low birth weight (LBW), small for gestational age (SGA), 5-minute Apgar <7, respiratory distress syndrome, hypoxic-ischemic encephalopathy, intraventricular hemorrhage, neonatal intensive care unit admission, sepsis, and death. Univariable and multivariable analyses were performed to examine the association between maternal race and ethnicity and perinatal outcomes.
    Results: A total of 2,729 women were included. In unadjusted analysis, non-Hispanic White women had higher rates of placental abruption and Hispanic women had higher rates of placental abruption and eclampsia. In multivariable analysis, non-Hispanic Black continued to have higher odds of placental abruption (adjusted odds ratio 4.16, 95% confidence interval 1.29-18.70), but the rest of the maternal outcomes did not differ between the groups. When comparing neonatal outcomes, PTB, SGA, and LBW were more frequent in, 5-minute Apgar <7 non-Hispanic Black and Hispanic women compared with non-Hispanic White women. In addition, 5-minute Apgar <7 and neonatal sepsis were more frequent in non-Hispanic Black neonates and neonatal death was more frequent in Hispanic neonates compared with non-Hispanic White women. In multivariable regression, neonates of non-Hispanic Black women had higher odds of PTB, SGA, LBW, 5-minute Apgar < 7, and sepsis compared with non-Hispanic White women. Similarly, neonates of Hispanic women had higher odds of SGA, LBW, and death.
    Conclusion: Significant racial and ethnic disparities were identified mainly in neonatal outcomes of women with chronic hypertension.
    Key points: · Non-Hispanic Black women with chronic hypertension had higher rates of placental abruption.. · Neonates of non-Hispanic Black women with chronic hypertension had higher odds of PTB, SGA, and LBW.. · Neonates of Hispanic women with chronic hypertension had higher odds of SGA, LBW, and neonatal death..
    MeSH term(s) Abruptio Placentae/epidemiology ; Eclampsia/epidemiology ; Ethnicity ; Female ; Humans ; Hypertension/epidemiology ; Infant, Newborn ; Infant, Newborn, Diseases/epidemiology ; Intensive Care Units, Neonatal ; Neonatal Sepsis ; Perinatal Death ; Placenta ; Pregnancy ; Premature Birth/epidemiology ; Retrospective Studies
    Language English
    Publishing date 2022-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/a-1745-2902
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  9. Article ; Online: The association between preeclampsia and ICD diagnosis of neonatal sepsis.

    Harrison, Rachel K / Palatnik, Anna

    Journal of perinatology : official journal of the California Perinatal Association

    2020  Volume 41, Issue 3, Page(s) 460–467

    Abstract: Objective: Infants born to mothers with preeclampsia are at risk for many short and long-term complications. The objective of this study was to examine the association between preeclampsia and ICD diagnosis of neonatal sepsis in a large United States ... ...

    Abstract Objective: Infants born to mothers with preeclampsia are at risk for many short and long-term complications. The objective of this study was to examine the association between preeclampsia and ICD diagnosis of neonatal sepsis in a large United States data set.
    Study design: A retrospective cohort study from the Consortium on Safe Labor. A total of 180,277 women with a singleton gestation greater than 23 weeks were included. The primary outcome, neonatal sepsis, was compared between women stratified by diagnosis of preeclampsia using univariable and multivariable analyses.
    Results: Of the 180,277 women eligible for analysis, 8331 (4.6%) were diagnosed with preeclampsia. Neonatal sepsis rates were higher among women diagnosed with preeclampsia (6.4 vs. 2.0%, p < 0.001). In multivariable logistic regression, adjusted for confounders, the association between preeclampsia and neonatal sepsis remained significant (adjusted OR = 1.30, 95% CI: 1.06-1.60).
    Conclusion: In this large cohort, the rate of neonatal sepsis ICD diagnosis was higher among women diagnosed with preeclampsia.
    MeSH term(s) Cohort Studies ; Female ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Neonatal Sepsis/diagnosis ; Neonatal Sepsis/epidemiology ; Pre-Eclampsia/diagnosis ; Pre-Eclampsia/epidemiology ; Pregnancy ; Retrospective Studies ; United States/epidemiology
    Language English
    Publishing date 2020-08-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645021-0
    ISSN 1476-5543 ; 0743-8346
    ISSN (online) 1476-5543
    ISSN 0743-8346
    DOI 10.1038/s41372-020-00774-0
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  10. Article ; Online: Effect of a Best-Practice Alert on the Rate of Smoking Cessation among Pregnant Women.

    Tvina, Alina / Tillis, Brian / Chen, Meinuo / MacBeth, Margaret / Tsaih, Shirng-Wern / Palatnik, Anna

    American journal of perinatology

    2023  

    Abstract: Objective:  This study aimed to determine if a best-practice alert (BPA) implementation increases the rate of smoking cessation during pregnancy and affects pregnancy outcomes associated with smoking.: Study design:  This was a pretest-posttest study ...

    Abstract Objective:  This study aimed to determine if a best-practice alert (BPA) implementation increases the rate of smoking cessation during pregnancy and affects pregnancy outcomes associated with smoking.
    Study design:  This was a pretest-posttest study design where a BPA was added to electronic medical records (EMR) of pregnant persons who reported active smoking. The BPA provided the 5A's method to conduct counseling on smoking cessation. The rates of smoking cessation during pregnancy were compared 1.5 years before and after implementation of the BPA. Secondary outcomes examined whether counseling on smoking cessation was done, the number of the counseling sessions during pregnancy, and obstetric outcomes associated with maternal smoking.
    Results:  After implementation of the BPA, the rate of smoking cessation in pregnancy increased from 17.5% prior to BPA implementation to 54.9% after BPA implementation (
    Conclusion:  The rate of smoking cessation and number of times pregnant persons were counseled increased after implementation of a BPA. The BPA could be a useful EMR tool to increase smoking cessation rates during pregnancy.
    Key points: · Smoking during pregnancy is a maternal and fetal concern.. · Prenatal care offers the chance to address smoking.. · BPA increases rates of smoking counseling and cessation..
    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/a-2091-5643
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