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  1. Article ; Online: Potential implications of SARS-CoV-2 on pregnancy.

    Tseng, Jen-Yu

    Taiwanese journal of obstetrics & gynecology

    2020  Volume 59, Issue 3, Page(s) 464–465

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Female ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Pregnancy ; Pregnancy Outcome ; Pregnant Women ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome
    Keywords covid19
    Language English
    Publishing date 2020-05-14
    Publishing country China (Republic : 1949- )
    Document type Letter
    ISSN 1875-6263
    ISSN (online) 1875-6263
    DOI 10.1016/j.tjog.2020.03.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Potential implications of SARS-CoV-2 on pregnancy

    Tseng, Jen-Yu

    Taiwanese Journal of Obstetrics and Gynecology

    2020  Volume 59, Issue 3, Page(s) 464–465

    Keywords Obstetrics and Gynaecology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 1028-4559
    DOI 10.1016/j.tjog.2020.03.025
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Impact of obesity on outcomes after surgical stabilization of multiple rib fractures: Evidence from the US nationwide inpatient sample.

    Liu, Yang-Fan / Chen, Te-Li / Tseng, Ching-Hsueh / Wang, Jen-Yu / Wang, Wen-Ching

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0299256

    Abstract: Background: Obesity is a global health issue with increasing prevalence. Surgical procedures, such as surgical stabilization of rib fractures (SSRF), may be affected by obesity-related complications. The objective of the study is to investigate the ... ...

    Abstract Background: Obesity is a global health issue with increasing prevalence. Surgical procedures, such as surgical stabilization of rib fractures (SSRF), may be affected by obesity-related complications. The objective of the study is to investigate the effects of obesity on SSRF outcomes in multiple rib fractures.
    Methods: This retrospective study analyzed data from adults aged ≥ 20 years in the Nationwide Inpatient Sample (NIS) database diagnosed with multiple rib fractures who underwent SSRF between 2005 and 2018. It investigated the relationship between obesity and in-patient outcomes, such as discharge status, length of stay (LOS), in-hospital mortality, hospital costs, and adverse events using logistic and linear regression analyses.
    Results: Analysis of data from 1,754 patients (morbidly obese: 87; obese: 106; normal weight: 1,561) revealed that morbid obesity was associated with longer LOS (aBeta = 0.07, 95% CI: 0.06, 0.07), higher hospital costs (aBeta = 47.35, 95% CI: 38.55, 56.14), increased risks of adverse events (aOR = 1.63, 95% CI: 1.02, 2.61), hemorrhage/need for transfusion (aOR = 1.77, 95% CI: 1.12, 2.79) and mechanical ventilation ≥ 96 hours (aOR = 2.14, 95% CI: 1.28, 3.58) compared to normal weight patients. Among patients with flail chest, morbid obesity was significantly associated with tracheostomy (aOR = 2.13, 95% CI: 1.05, 4.32), ARDS/respiratory failure (aOR = 2.01, 95% CI: 1.09, 3.70), and mechanical ventilation ≥ 96 hours (aOR = 2.80, 95% CI: 1.47, 5.32). In contrast, morbid obesity had no significant associations with these adverse respiratory outcomes among patients without a flail chest (p > 0.05).
    Conclusions: Morbid obesity is associated with adverse outcomes following SSRF for multiple rib fractures, especially for flail chest patients.
    MeSH term(s) Adult ; Humans ; Inpatients ; Rib Fractures/complications ; Rib Fractures/surgery ; Obesity, Morbid/complications ; Flail Chest ; Retrospective Studies
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0299256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Protecting against COVID-19 aerosol infection during intubation.

    Tseng, Jen-Yu / Lai, Hsien-Yung

    Journal of the Chinese Medical Association : JCMA

    2020  Volume 83, Issue 6, Page(s) 582

    MeSH term(s) Aerosols ; Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Intubation, Intratracheal ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Chemical Substances Aerosols
    Keywords covid19
    Language English
    Publishing date 2020-04-17
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 2107283-8
    ISSN 1728-7731 ; 1726-4901
    ISSN (online) 1728-7731
    ISSN 1726-4901
    DOI 10.1097/JCMA.0000000000000324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The relationship between serum CA-125 level and recurrence in surgical stage I endometrial cancer patients.

    Wu, Hua-Hsi / Chou, Hung-Tse / Tseng, Jen-Yu / Chan, I-San / Chen, Yi-Jen

    Journal of the Chinese Medical Association : JCMA

    2023  Volume 86, Issue 11, Page(s) 1001–1007

    Abstract: Background: The majority of patients diagnosed with early stage endometrial cancer have a favorable prognosis; however, approximately 10% to 15% experience a recurrence. Therefore, the aim of the present study was to evaluate whether postoperative ... ...

    Abstract Background: The majority of patients diagnosed with early stage endometrial cancer have a favorable prognosis; however, approximately 10% to 15% experience a recurrence. Therefore, the aim of the present study was to evaluate whether postoperative carbohydrate antigen 125 (CA-125) levels could be used to predict recurrence and recurrence-free survival (RFS) in patients with surgical stage I endometrial cancer.
    Methods: We enrolled a total of 518 patients with stage I endometrial cancer who underwent surgical treatment between January 2010 and March 2019. Serum CA-125 levels were measured prior to surgery, as well as 6 to 12 months after surgery. Subsequently, the correlations between the CA-125 levels, cancer recurrence, and RFS were analyzed.
    Results: Although the preoperative CA-125 level was not associated with the risk of cancer recurrence, the postoperative CA-125 level was found to be the only independent predictor of recurrence in both univariate and multivariate analyses. Additionally, we found that a postoperative CA-125 cutoff value of 13.75 U/mL yielded the best sensitivity and specificity for predicting cancer recurrence. Patients with a postoperative CA-125 level ≥13.75 U/mL, and those with a level <13.75 U/mL, had a median time to recurrence and a 5-year RFS rate of 35.5 vs 50.5 months and 84.7 vs 94.4%, respectively. Additionally, postoperative CA-125 levels were not found to be correlated with preoperative levels.
    Conclusion: In patients with stage I endometrial cancer, a postoperative CA-125 level ≥13.75 U/mL was found to be significantly correlated with a higher recurrence rate, as well as a shorter RFS. Therefore, obtaining a follow-up CA-125 level within 6 to 12 months after staging surgery may be a promising noninvasive biomarker for predicting recurrence.
    MeSH term(s) Female ; Humans ; Neoplasm Staging ; Neoplasm Recurrence, Local ; Prognosis ; Endometrial Neoplasms/pathology ; CA-125 Antigen ; Retrospective Studies
    Chemical Substances CA-125 Antigen
    Language English
    Publishing date 2023-08-29
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2107283-8
    ISSN 1728-7731 ; 1726-4901
    ISSN (online) 1728-7731
    ISSN 1726-4901
    DOI 10.1097/JCMA.0000000000000985
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Mechanosensitive bonds induced complex cell motility patterns

    Lo, Jen-Yu / Tseng, Yuan-Heng / Chen, Hsuan-Yi

    2023  

    Abstract: The one-dimensional crawling movement of a cell is considered in this theoretical study. Our active gel model shows that for a cell with weakly mechanosensitive adhesion complexes, as myosin contractility increases, a cell starts to move at a constant ... ...

    Abstract The one-dimensional crawling movement of a cell is considered in this theoretical study. Our active gel model shows that for a cell with weakly mechanosensitive adhesion complexes, as myosin contractility increases, a cell starts to move at a constant velocity. As the mechanosensitivity of the adhesion complexes increases, a cell can exhibit stick-slip motion. Finally, a cell with highly mechanosensitive adhesion complexes exhibits periodic back-and-forth migration. A simplified model which assumes that the cell crawling dynamics are controlled by the evolution of the myosin density dipole and the asymmetry of adhesion complex distribution captures the motility behaviors of crawling cells qualitatively. It suggests that the complex cell crawling behaviors observed in the experiments could result from the interplay between the distribution of contractile force and mechanosensitive bonds.
    Keywords Condensed Matter - Soft Condensed Matter ; Physics - Biological Physics
    Subject code 612
    Publishing date 2023-01-04
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: A new protective barrier to reduce the aerosol dispersion in dental clinics during Omicron Covid-19 pandemic.

    Teng, Wei-Chi / Chu, Ya-Chun / Tseng, Jen-Yu / Lai, Hsien-Yung

    Journal of the Chinese Medical Association : JCMA

    2022  Volume 85, Issue 7, Page(s) 808–809

    MeSH term(s) Aerosols ; COVID-19 ; Dental Clinics ; Humans ; Pandemics/prevention & control ; SARS-CoV-2
    Chemical Substances Aerosols
    Language English
    Publishing date 2022-06-30
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2107283-8
    ISSN 1728-7731 ; 1726-4901
    ISSN (online) 1728-7731
    ISSN 1726-4901
    DOI 10.1097/JCMA.0000000000000754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A disposable envelope for video-assisted intubating stylet during tracheal intubation in COVID-19 pandemic.

    Tseng, Jen-Yu / Hsu, Steven H / Lai, Hsien-Yung

    Journal of the Chinese Medical Association : JCMA

    2021  Volume 85, Issue 1, Page(s) 136

    MeSH term(s) COVID-19/epidemiology ; Humans ; Intubation, Intratracheal/instrumentation ; SARS-CoV-2 ; Video-Assisted Techniques and Procedures
    Language English
    Publishing date 2021-11-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2107283-8
    ISSN 1728-7731 ; 1726-4901
    ISSN (online) 1728-7731
    ISSN 1726-4901
    DOI 10.1097/JCMA.0000000000000671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Impaired motor skills and proprioceptive function in Mandarin-speaking children with developmental language disorder.

    Hsu, Hsin-Jen / Tseng, Yu-Ting

    Brain and language

    2024  Volume 251, Page(s) 105390

    Abstract: This study examined proprioceptive acuity and its relationship with motor function in Mandarin-speaking children with and without developmental language disorder (DLD). Fifteen children aged 9-12 years with DLD and 15 age- and sex-matched typically ... ...

    Abstract This study examined proprioceptive acuity and its relationship with motor function in Mandarin-speaking children with and without developmental language disorder (DLD). Fifteen children aged 9-12 years with DLD and 15 age- and sex-matched typically developing (TD) children participated in this study. Children's motor function was assessed using the second edition of the Movement Assessment Battery for Children (MABC-2). Their proprioceptive acuity was measured based on the absolute error (i.e., proprioceptive bias) and variable error (i.e., proprioceptive precision) when performing joint position matching tasks. Compared with the TD group, the DLD group exhibited impaired motor function and poorer proprioceptive acuity, as evidenced by the lower scores on the MABC-2 and the higher rates of absolute and variable errors in the joint position matching tasks. A significant association between the proprioceptive bias (absolute error) and the MABC-2 total score was also observed in the combined cohort of children with and without DLD. We conclude that DLD is associated with proprioceptive dysfunction.
    MeSH term(s) Child ; Humans ; Motor Skills ; Proprioception ; Movement ; Language Development Disorders ; Language Tests
    Language English
    Publishing date 2024-02-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 7448-2
    ISSN 1090-2155 ; 0093-934X
    ISSN (online) 1090-2155
    ISSN 0093-934X
    DOI 10.1016/j.bandl.2024.105390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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