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  1. Article ; Online: Targeting regulatory T cells for improving cancer therapy: Challenges and prospects.

    Dwarakanath, Bilikere S / Farooque, Abdullah / Gupta, Seema

    Cancer reports (Hoboken, N.J.)

    2018  Volume 1, Issue 1, Page(s) e21105

    Abstract: Objective: Regulatory T cells (Tregs) play a central role in immune responses to infectious agents and tumors. Paradoxically, Tregs protect self-cells from the immune response as a part of peripheral tolerance and prevents autoimmune disorders, whereas ... ...

    Abstract Objective: Regulatory T cells (Tregs) play a central role in immune responses to infectious agents and tumors. Paradoxically, Tregs protect self-cells from the immune response as a part of peripheral tolerance and prevents autoimmune disorders, whereas during the process of carcinogenesis, they are exploited by tumor cells for protection against antitumor immune responses. Therefore, Tregs are often considered as a major obstacle in anticancer therapy. The objective of this review is to provide a current understanding on Tregs as a potential cellular target for achieving therapeutic gain and discuss various approaches that are implicated at preclinical and clinical scenario.
    Recent findings: Several approaches like immunotherapy and adjuvant chemotherapy, which reduce Tregs population, have been found to be useful in improving local tumor control. Our recent observations with the glycolytic inhibitor, 2-deoxy-D-glucose, established as an adjuvant in radiotherapy and chemotherapy of tumors also show that potential of 2-deoxy-D-glucose to improve local tumor control is linked with its ability to reduce the Tregs pool.
    Conclusions: Several published studies and emerging evidences indicate that suppression of Treg numbers, infiltration into the tumors, and function can improve the cancer therapy by enhancing the antitumor immunity.
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Cancer Vaccines/administration & dosage ; Chemoradiotherapy/methods ; Humans ; Lymphocyte Depletion/methods ; Neoplasms/immunology ; Neoplasms/therapy ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/radiation effects ; Tumor Escape/drug effects ; Tumor Escape/radiation effects ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/immunology
    Chemical Substances Cancer Vaccines
    Language English
    Publishing date 2018-05-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ISSN 2573-8348
    ISSN (online) 2573-8348
    DOI 10.1002/cnr2.1105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: T-Regulatory Cells In Tumor Progression And Therapy.

    Verma, Amit / Mathur, Rohit / Farooque, Abdullah / Kaul, Vandana / Gupta, Seema / Dwarakanath, Bilikere S

    Cancer management and research

    2019  Volume 11, Page(s) 10731–10747

    Abstract: Regulatory T cells (Tregs) are important members of the immune system regulating the host responses to infection and neoplasms. Tregs prevent autoimmune disorders by protecting the host-cells from an immune response, related to the peripheral tolerance. ... ...

    Abstract Regulatory T cells (Tregs) are important members of the immune system regulating the host responses to infection and neoplasms. Tregs prevent autoimmune disorders by protecting the host-cells from an immune response, related to the peripheral tolerance. However, tumor cells use Tregs as a shield to protect themselves against anti-tumor immune response. Thus, Tregs are a hurdle in achieving the complete potential of anti-cancer therapies including immunotherapy. This has prompted the development of novel adjuvant therapies that obviate their negative effects thereby enhancing the therapeutic efficacy. Our earlier studies have shown the efficacy of the glycolytic inhibitor, 2-deoxy-D-glucose (2-DG) by reducing the induced Tregs pool and enhance immune stimulation as well as local tumor control. These findings have suggested its potential for enhancing the efficacy of immunotherapy, besides radiotherapy and chemotherapy. This review provides a brief account of the current status of Tregs as a component of the immune-biology of tumors and various preclinical and clinical strategies pursued to obviate the limitations imposed by them in achieving therapeutic efficacy.
    Language English
    Publishing date 2019-12-24
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2508013-1
    ISSN 1179-1322
    ISSN 1179-1322
    DOI 10.2147/CMAR.S228887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Fabrication and fluorescent labeling of guar gum nanoparticles in a surfactant free aqueous environment.

    Ghosh, Sumanta Kumar / Abdullah, Farooque / Mukherjee, Arup

    Materials science & engineering. C, Materials for biological applications

    2015  Volume 46, Page(s) 521–529

    Abstract: Guar gum (GG) is a galactomannan obtained from the seeds of Cyamopsis tetragonoloba. GG polysaccharide is used in a range of technology arenas and its properties in water environment elicited a lot of interest. We report a simple acid hydrolysis ... ...

    Abstract Guar gum (GG) is a galactomannan obtained from the seeds of Cyamopsis tetragonoloba. GG polysaccharide is used in a range of technology arenas and its properties in water environment elicited a lot of interest. We report a simple acid hydrolysis technique to derive water dispersible spherical nanoparticles from GG for the first time without any stabilizing surfactant. The particles demonstrated colloidal stability and were observed to carry negative surface charges in aqueous environment. The TEM study of guar gum nanoparticles (GGn) indicated a size range of 30-80 nm with a mean at 48.8 nm. Mineral acid at apposite concentration have apparently solubilized the amorphous regions of the polymer chain leaving the crystalline parts. GGn were further covalently functionalized in aqueous environment with fluorescein isothiocyanate (FITC) using a hydroxy-propyl amine spacer group. Nanoparticle fluorescence intensity can be modulated with pH changes and a significant augmentation in the intensity was noticed at the physiologically relevant range of 6-8. New fluorescently labeled nanoparticles have potential for applications in bioimaging, biomolecular interaction studies and as a pH sensing probe in sub cellular environment.
    MeSH term(s) Fluorescent Dyes ; Galactans ; Mannans ; Microscopy, Electron, Transmission ; Nanoparticles ; Plant Gums ; Spectrometry, Fluorescence ; Spectrophotometry, Ultraviolet ; Surface-Active Agents/analysis ; Water/chemistry ; X-Ray Diffraction
    Chemical Substances Fluorescent Dyes ; Galactans ; Mannans ; Plant Gums ; Surface-Active Agents ; Water (059QF0KO0R) ; guar gum (E89I1637KE)
    Language English
    Publishing date 2015-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2012160-X
    ISSN 1873-0191 ; 0928-4931
    ISSN (online) 1873-0191
    ISSN 0928-4931
    DOI 10.1016/j.msec.2014.10.080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Polarization of macrophages towards M1 phenotype by a combination of 2-deoxy-d-glucose and radiation: Implications for tumor therapy.

    Farooque, Abdullah / Afrin, Farhat / Adhikari, Jawahar Singh / Dwarakanath, Bilikere Srinivasa Rao

    Immunobiology

    2016  Volume 221, Issue 2, Page(s) 269–281

    Abstract: 2-Deoxy-d-glucose (2-DG) has been found to enhance the cytotoxicity of ionizing radiation and chemotherapeutic drugs in several tumor cell lines in vitro. Systemic administration of 2-DG together with localized irradiation of the tumor leads to tumor ... ...

    Abstract 2-Deoxy-d-glucose (2-DG) has been found to enhance the cytotoxicity of ionizing radiation and chemotherapeutic drugs in several tumor cell lines in vitro. Systemic administration of 2-DG together with localized irradiation of the tumor leads to tumor regression and cure (disease free survival), which correlate with the differential levels of anti-tumor immunity observed in Ehrlich ascites tumor (EAT) bearing mice. Macrophages being a major player of the innate immune system, we investigated the activation status of splenic macrophages during radio-sensitization of EAT in mice as well as in peritoneal macrophages ex vivo and macrophagic cell line (Raw 264.7) in vitro. Results suggest that under in vivo conditions, the combined treatment (2-DG+radiation) restores the M1 phenotype in spleen that correlated with the tumor response. However, 2-DG neither induced significant cytotoxicity nor enhanced radiation-induced cell death in peritoneal macrophages and the macrophage cell line (Raw 264.7). Further, increased arborization and enhanced functional status (expression of MHC class II, CD80, CD86 and phagocytosis) were observed after the combined treatment. Besides this activation, the combined treatment also skewed the macrophages towards M1 phenotype as evidenced by the enhanced secretion of IL-12, IL-2, TNF-α and IFN-γ. These observations suggest that 2-DG not only preserves the survival of normal macrophages during irradiation, but also activates macrophages by polarizing towards M1 phenotype, which is known to be tumoricidal in nature. This study for the first time sheds light on a potential antitumor immune activation by 2-DG involving macrophagic stimulation during in vivo radio-sensitization of tumors, besides the other known antitumor effects of this glucose analogue.
    MeSH term(s) Animals ; B7-1 Antigen/genetics ; B7-1 Antigen/immunology ; B7-2 Antigen/genetics ; B7-2 Antigen/immunology ; Carcinoma, Ehrlich Tumor/genetics ; Carcinoma, Ehrlich Tumor/immunology ; Carcinoma, Ehrlich Tumor/pathology ; Carcinoma, Ehrlich Tumor/therapy ; Cell Differentiation/drug effects ; Cell Differentiation/radiation effects ; Cell Line ; Deoxyglucose/pharmacology ; Gamma Rays/therapeutic use ; Gene Expression Regulation ; Histocompatibility Antigens Class II/genetics ; Histocompatibility Antigens Class II/immunology ; Interferon-gamma/genetics ; Interferon-gamma/immunology ; Interleukin-12/genetics ; Interleukin-12/immunology ; Interleukin-2/genetics ; Interleukin-2/immunology ; Macrophages, Peritoneal/drug effects ; Macrophages, Peritoneal/immunology ; Macrophages, Peritoneal/pathology ; Macrophages, Peritoneal/radiation effects ; Male ; Mice ; Phagocytosis/drug effects ; Phagocytosis/radiation effects ; Primary Cell Culture ; Signal Transduction ; Tumor Burden/drug effects ; Tumor Burden/radiation effects ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology
    Chemical Substances B7-1 Antigen ; B7-2 Antigen ; Cd86 protein, mouse ; Histocompatibility Antigens Class II ; Interleukin-2 ; Tumor Necrosis Factor-alpha ; Interleukin-12 (187348-17-0) ; Interferon-gamma (82115-62-6) ; Deoxyglucose (9G2MP84A8W)
    Language English
    Publishing date 2016-02
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 563292-4
    ISSN 1878-3279 ; 0171-2985
    ISSN (online) 1878-3279
    ISSN 0171-2985
    DOI 10.1016/j.imbio.2015.10.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Urban Horticulture for Food Secure Cities through and beyond COVID-19

    Muhammad Mumtaz Khan / Muhammad Tahir Akram / Rhonda Janke / Rashad Waseem Khan Qadri / Abdullah Mohammed Al-Sadi / Aitazaz A. Farooque

    Sustainability, Vol 12, Iss 9592, p

    2020  Volume 9592

    Abstract: Sufficient production, consistent food supply, and environmental protection in urban +settings are major global concerns for future sustainable cities. Currently, sustainable food supply is under intense pressure due to exponential population growth, ... ...

    Abstract Sufficient production, consistent food supply, and environmental protection in urban +settings are major global concerns for future sustainable cities. Currently, sustainable food supply is under intense pressure due to exponential population growth, expanding urban dwellings, climate change, and limited natural resources. The recent novel coronavirus 2019 (COVID-19) pandemic crisis has impacted sustainable fresh food supply, and has disrupted the food supply chain and prices significantly. Under these circumstances, urban horticulture and crop cultivation have emerged as potential ways to expand to new locations through urban green infrastructure. Therefore, the objective of this study is to review the salient features of contemporary urban horticulture, in addition to illustrating traditional and innovative developments occurring in urban environments. Current urban cropping systems, such as home gardening, community gardens, edible landscape, and indoor planting systems, can be enhanced with new techniques, such as vertical gardening, hydroponics, aeroponics, aquaponics, and rooftop gardening. These modern techniques are ecofriendly, energy- saving, and promise food security through steady supplies of fresh fruits and vegetables to urban neighborhoods. There is a need, in this modern era, to integrate information technology tools in urban horticulture, which could help in maintaining consistent food supply during (and after) a pandemic, as well as make agriculture more sustainable.
    Keywords cropping systems ; ecological sustainability ; hygienic food ; sustainable food supply ; urban horticulture ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 710
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Guar gum benzoate nanoparticle reinforced gelatin films for enhanced thermal insulation, mechanical and antimicrobial properties.

    Kundu, Sonia / Das, Aatrayee / Basu, Aalok / Abdullah, Md Farooque / Mukherjee, Arup

    Carbohydrate polymers

    2017  Volume 170, Page(s) 89–98

    Abstract: This work relates to guar gum benzoate self assembly nanoparticles synthesis and nano composite films development with gelatin. Guar gum benzoate was synthesized in a Hofmeister cation guided homogeneous phase reaction. Self assembly polysaccharide ... ...

    Abstract This work relates to guar gum benzoate self assembly nanoparticles synthesis and nano composite films development with gelatin. Guar gum benzoate was synthesized in a Hofmeister cation guided homogeneous phase reaction. Self assembly polysaccharide nanoparticles were prepared in solvent displacement technique. Electron microscopy and DLS study confirmed uniform quasi spherical nanoparticles with ζ-potential - 28.7mV. Nanocomposite films were further developed in gelatin matrix. The film capacity augmenting due to nanoparticles incorporation was noteworthy. Superior barrier properties, reinforcing and thermal insulation effects were observed in films dispersed with 20% w/w nanoparticles. Detailed FTIR studies and thermal analysis confirmed nanoparticles interactions in the film matrix. The nanocomposite film water vapour permeability was at 0.75gmm
    MeSH term(s) Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Bacteria/drug effects ; Benzoates/chemistry ; Galactans/chemistry ; Gelatin/chemistry ; Mannans/chemistry ; Mechanical Phenomena ; Nanoparticles/chemistry ; Plant Gums/chemistry ; Temperature
    Chemical Substances Anti-Infective Agents ; Benzoates ; Galactans ; Mannans ; Plant Gums ; gelatin film ; Gelatin (9000-70-8) ; guar gum (E89I1637KE)
    Language English
    Publishing date 2017-08-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2017.04.056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cationic guar gum orchestrated environmental synthesis for silver nano-bio-composite films.

    Abdullah, Md Farooque / Ghosh, Sumanta Kumar / Basu, Sreyasree / Mukherjee, Arup

    Carbohydrate polymers

    2015  Volume 134, Page(s) 30–37

    Abstract: This work is meant for environmentally friendly synthesis and functional evaluation of silver nanoparticles in a newer cationic guar biopolymer (GGAA). Assembly of molecules in lower size range (∼ 10 nm) was attained in a biopolymer entrapped bottom-up ... ...

    Abstract This work is meant for environmentally friendly synthesis and functional evaluation of silver nanoparticles in a newer cationic guar biopolymer (GGAA). Assembly of molecules in lower size range (∼ 10 nm) was attained in a biopolymer entrapped bottom-up synthesis. Guar gum is a filming biopolymer. Nanoparticles encaged in cationic guar (GGAgnC) were preserved as films for months without any significant effect on particle size, distribution or plasmonic intensity. The new nano-bio-composite and films were characterized fully in FTIR, XRD, SEM and TEM studies. Silver nanoparticles induced surface water repellency remarkably and lowered moisture permeability. GGAgnC film water contact angle was recorded as 115° while, that in case of GGAA was 59°. GGAgnC expressed intense antimicrobial activity when tested against a range of microorganisms. Immobilized silver nanoparticles in GGAA can feasibly be used as filming microbicidals suitable for textiles, packaging and biomedical device applications.
    MeSH term(s) Amination ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Bacteria/drug effects ; Cations/chemical synthesis ; Cations/chemistry ; Cations/pharmacology ; Galactans/chemical synthesis ; Galactans/chemistry ; Galactans/pharmacology ; Green Chemistry Technology/methods ; Mannans/chemical synthesis ; Mannans/chemistry ; Mannans/pharmacology ; Metal Nanoparticles/chemistry ; Metal Nanoparticles/ultrastructure ; Nanotechnology/methods ; Plant Gums/chemical synthesis ; Plant Gums/chemistry ; Plant Gums/pharmacology ; Silver/chemistry ; Silver/pharmacology ; Steam ; Water Microbiology
    Chemical Substances Anti-Bacterial Agents ; Cations ; Galactans ; Mannans ; Plant Gums ; Steam ; Silver (3M4G523W1G) ; guar gum (E89I1637KE)
    Language English
    Publishing date 2015--10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2015.06.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Semi-interpenetrating hydrogels from carboxymethyl guar gum and gelatin for ciprofloxacin sustained release.

    Ghosh, Sumanta Kumar / Das, Aatrayee / Basu, Aalok / Halder, Asim / Das, Suvadra / Basu, Sreyasree / Abdullah, Md Farooque / Mukherjee, Arup / Kundu, Sonia

    International journal of biological macromolecules

    2018  Volume 120, Issue Pt B, Page(s) 1823–1833

    Abstract: The present work reports the synthesis of new generation semi-interpenetrating (s-IPN) hydrogels from carboxymethyl guar gum (CMGG) and gelatin with enhanced gel properties for suitable drug delivery applications. Hydrogels are three dimensional polymer ... ...

    Abstract The present work reports the synthesis of new generation semi-interpenetrating (s-IPN) hydrogels from carboxymethyl guar gum (CMGG) and gelatin with enhanced gel properties for suitable drug delivery applications. Hydrogels are three dimensional polymer networks which respond to water and ion interactions. Irreversible s-IPN hydrogels were prepared by CMGG interactions in gelatin and characterized in FT-IR, SEM and thermal studies. CMGG was synthesized by Hofmeister ion guided homogeneous phase reactions. The swelling kinetics of the newer s-IPN hydrogels followed Schott's pseudo second order model. Furthermore, the hydrogels were hemocompatible, non-cytotoxic and appropriate for applications in physiological environment. Model drug ciprofloxacin was loaded within the hydrogels and the drug release was found to be a combination of both diffusion and hydrogel degradation. New generation s-IPN biopolymer hydrogels of carboxymethyl guar gum and gelatin holds promise for its application as sustained drug delivery device or alternatively as hydrogel sorbents for bio-toxins and molecules of biomedical importance.
    MeSH term(s) Animals ; Ciprofloxacin/chemistry ; Delayed-Action Preparations ; Drug Carriers/chemistry ; Drug Carriers/toxicity ; Galactans/chemistry ; Gelatin/chemistry ; Hydrogels/chemistry ; Hydrogels/toxicity ; Kinetics ; Mannans/chemistry ; Materials Testing ; Mechanical Phenomena ; Mice ; NIH 3T3 Cells ; Plant Gums/chemistry ; Temperature
    Chemical Substances Delayed-Action Preparations ; Drug Carriers ; Galactans ; Hydrogels ; Mannans ; Plant Gums ; carboxymethyl guar gum ; Ciprofloxacin (5E8K9I0O4U) ; Gelatin (9000-70-8)
    Language English
    Publishing date 2018-10-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2018.09.212
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Cationic guar gum orchestrated environmental synthesis for silver nano-bio-composite films

    Abdullah, Md Farooque / Arup Mukherjee / Sreyasree Basu / Sumanta Kumar Ghosh

    Carbohydrate polymers. 2015 Dec. 10, v. 134

    2015  

    Abstract: This work is meant for environmentally friendly synthesis and functional evaluation of silver nanoparticles in a newer cationic guar biopolymer (GGAA). Assembly of molecules in lower size range (∼10nm) was attained in a biopolymer entrapped bottom–up ... ...

    Abstract This work is meant for environmentally friendly synthesis and functional evaluation of silver nanoparticles in a newer cationic guar biopolymer (GGAA). Assembly of molecules in lower size range (∼10nm) was attained in a biopolymer entrapped bottom–up synthesis. Guar gum is a filming biopolymer. Nanoparticles encaged in cationic guar (GGAgnC) were preserved as films for months without any significant effect on particle size, distribution or plasmonic intensity. The new nano-bio-composite and films were characterized fully in FTIR, XRD, SEM and TEM studies. Silver nanoparticles induced surface water repellency remarkably and lowered moisture permeability. GGAgnC film water contact angle was recorded as 115° while, that in case of GGAA was 59°. GGAgnC expressed intense antimicrobial activity when tested against a range of microorganisms. Immobilized silver nanoparticles in GGAA can feasibly be used as filming microbicidals suitable for textiles, packaging and biomedical device applications.
    Keywords anti-infective properties ; biopolymers ; contact angle ; fabrics ; Fourier transform infrared spectroscopy ; guar gum ; medical equipment ; microorganisms ; nanoparticles ; nanosilver ; packaging ; particle size ; permeability ; scanning electron microscopy ; silver ; surface water ; transmission electron microscopy ; X-ray diffraction
    Language English
    Dates of publication 2015-1210
    Size p. 30-37.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2015.06.029
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Guar gum benzoate nanoparticle reinforced gelatin films for enhanced thermal insulation, mechanical and antimicrobial properties

    Kundu, Sonia / Aalok Basu / Aatrayee Das / Arup Mukherjee / Md. Farooque Abdullah

    Carbohydrate polymers. 2017 Aug. 15, v. 170

    2017  

    Abstract: This work relates to guar gum benzoate self assembly nanoparticles synthesis and nano composite films development with gelatin. Guar gum benzoate was synthesized in a Hofmeister cation guided homogeneous phase reaction. Self assembly polysaccharide ... ...

    Abstract This work relates to guar gum benzoate self assembly nanoparticles synthesis and nano composite films development with gelatin. Guar gum benzoate was synthesized in a Hofmeister cation guided homogeneous phase reaction. Self assembly polysaccharide nanoparticles were prepared in solvent displacement technique. Electron microscopy and DLS study confirmed uniform quasi spherical nanoparticles with ζ-potential − 28.7mV. Nanocomposite films were further developed in gelatin matrix. The film capacity augmenting due to nanoparticles incorporation was noteworthy. Superior barrier properties, reinforcing and thermal insulation effects were observed in films dispersed with 20% w/w nanoparticles. Detailed FTIR studies and thermal analysis confirmed nanoparticles interactions in the film matrix. The nanocomposite film water vapour permeability was at 0.75gmm−1kPa−1h−1, thermal conductivity 0.39Wm−1K−1 and the tensile strength were recorded at 3.87MPa. The final film expressed excellent antimicrobial properties against water born gram negative and gram positive bacteria.
    Keywords antibacterial properties ; cations ; electron microscopy ; films (materials) ; Fourier transform infrared spectroscopy ; gelatin ; Gram-positive bacteria ; guar gum ; insulating materials ; nanocomposites ; nanoparticles ; permeability ; solvents ; tensile strength ; thermal analysis ; thermal conductivity ; water vapor ; zeta potential
    Language English
    Dates of publication 2017-0815
    Size p. 89-98.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2017.04.056
    Database NAL-Catalogue (AGRICOLA)

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