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  1. Book ; Online: Gated Deeper Models are Effective Factor Learners

    Guo, Jingjing

    2023  

    Abstract: Precisely forecasting the excess returns of an asset (e.g., Tesla stock) is beneficial to all investors. However, the unpredictability of market dynamics, influenced by human behaviors, makes this a challenging task. In prior research, researcher have ... ...

    Abstract Precisely forecasting the excess returns of an asset (e.g., Tesla stock) is beneficial to all investors. However, the unpredictability of market dynamics, influenced by human behaviors, makes this a challenging task. In prior research, researcher have manually crafted among of factors as signals to guide their investing process. In contrast, this paper view this problem in a different perspective that we align deep learning model to combine those human designed factors to predict the trend of excess returns. To this end, we present a 5-layer deep neural network that generates more meaningful factors in a 2048-dimensional space. Modern network design techniques are utilized to enhance robustness training and reduce overfitting. Additionally, we propose a gated network that dynamically filters out noise-learned features, resulting in improved performance. We evaluate our model over 2,000 stocks from the China market with their recent three years records. The experimental results show that the proposed gated activation layer and the deep neural network could effectively overcome the problem. Specifically, the proposed gated activation layer and deep neural network contribute to the superior performance of our model. In summary, the proposed model exhibits promising results and could potentially benefit investors seeking to optimize their investment strategies.

    Comment: 7 pages
    Keywords Quantitative Finance - Pricing of Securities ; Computer Science - Machine Learning
    Subject code 006
    Publishing date 2023-05-18
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Significance of comprehensive nursing in preventing postoperative vascular complications in patients who underwent interventional embolization of the intracranial artery.

    Guo, JingJing / Chen, XiaoHong

    Asian journal of surgery

    2023  Volume 46, Issue 8, Page(s) 3073–3074

    MeSH term(s) Humans ; Embolization, Therapeutic/adverse effects ; Arteries ; Intracranial Aneurysm/complications ; Intracranial Aneurysm/surgery ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2023-03-04
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.02.087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Potential-resolved electrochemiluminescence for simultaneous determination of multiplex bladder cancer markers.

    Wang, Junke / Guo, Fenglian / Zhang, Jingjing / Chao, Jie

    Chemical communications (Cambridge, England)

    2024  Volume 60, Issue 34, Page(s) 4609–4612

    Abstract: A novel ECL immunosensor was developed for simultaneous determination of multiplex bladder cancer markers. DNA tetrahedra act as capture probes, while Ru-MOF@AuNPs and AuAgNCs act as signal reporters, yielding well-separated signals reflecting NUMA1 and ... ...

    Abstract A novel ECL immunosensor was developed for simultaneous determination of multiplex bladder cancer markers. DNA tetrahedra act as capture probes, while Ru-MOF@AuNPs and AuAgNCs act as signal reporters, yielding well-separated signals reflecting NUMA1 and CFHR1 concentrations. This strategy offers a new platform for clinical immunoassays, enabling simultaneous multiplex tumor marker detection.
    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d4cc00996g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prediction of Disease-Free Survival in Breast Cancer using Deep Learning with Ultrasound and Mammography: A Multicenter Study.

    Han, Junqi / Hua, Hui / Fei, Jie / Liu, Jingjing / Guo, Yijun / Ma, Wenjuan / Chen, Jingjing

    Clinical breast cancer

    2024  Volume 24, Issue 3, Page(s) 215–226

    Abstract: Background: Breast cancer is a leading cause of cancer morbility and mortality in women. The possibility of overtreatment or inappropriate treatment exists, and methods for evaluating prognosis need to be improved.: Materials and methods: Patients ( ... ...

    Abstract Background: Breast cancer is a leading cause of cancer morbility and mortality in women. The possibility of overtreatment or inappropriate treatment exists, and methods for evaluating prognosis need to be improved.
    Materials and methods: Patients (from January 2013 to December 2018) were recruited and divided into a training group and a testing group. All patients were followed for more than 3 years. Patients were divided into a disease-free group and a recurrence group based on follow up results at 3 years. Ultrasound (US) and mammography (MG) images were collected to establish deep learning models (DLMs) using ResNet50. Clinical data, MG, and US characteristics were collected to select independent prognostic factors using a cox proportional hazards model to establish a clinical model. DLM and independent prognostic factors were combined to establish a combined model.
    Results: In total, 1242 patients were included. Independent prognostic factors included age, neoadjuvant chemotherapy, HER2, orientation, blood flow, dubious calcification, and size. We established 5 models: the US DLM, MG DLM, US + MG DLM, clinical and combined model. The combined model using US images, MG images, and pathological, clinical, and radiographic characteristics had the highest predictive performance (AUC = 0.882 in the training group, AUC = 0.739 in the testing group).
    Conclusion: DLMs based on the combination of US, MG, and clinical data have potential as predictive tools for breast cancer prognosis.
    MeSH term(s) Female ; Humans ; Breast Neoplasms/therapy ; Breast Neoplasms/drug therapy ; Disease-Free Survival ; Deep Learning ; Mammography/methods ; Breast/pathology ; Retrospective Studies
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2106734-X
    ISSN 1938-0666 ; 1526-8209
    ISSN (online) 1938-0666
    ISSN 1526-8209
    DOI 10.1016/j.clbc.2024.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Childhood maltreatment and Internet addiction among Chinese adolescents: A moderated mediation model.

    Gu, JingJing / Guo, YuanYuan / Wang, Jin-Liang

    Journal of affective disorders

    2024  Volume 350, Page(s) 721–727

    Abstract: Although childhood maltreatment has been suggested to play an important role in developing Internet addiction among adolescents, little is known about the mediating and moderating mechanisms underlying this association. The present study investigated (a) ...

    Abstract Although childhood maltreatment has been suggested to play an important role in developing Internet addiction among adolescents, little is known about the mediating and moderating mechanisms underlying this association. The present study investigated (a) the mediating role of maladaptive cognitive emotion regulation strategy (MCERS) in the association between childhood maltreatment and Internet addiction, and (b) the moderating role of peer support in the relationship between childhood maltreatment and Internet addiction. A sample of 4163 Chinese adolescents (50.3 % females, M
    MeSH term(s) Female ; Humans ; Adolescent ; Male ; Child ; Internet Addiction Disorder/epidemiology ; Behavior, Addictive/epidemiology ; Behavior, Addictive/psychology ; Emotional Regulation ; Child Abuse ; China/epidemiology ; Internet
    Language English
    Publishing date 2024-01-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2024.01.175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The temporal mechanism of contextual emotions' effects on novel abstract and concrete word learning.

    Zhao, Jingjie / Guo, Jingjing

    Neuroscience letters

    2023  Volume 805, Page(s) 137227

    Abstract: While previous studies have explored the neurocognitive mechanism of novel word learning under sentential contexts, few studies have probed the potential effects of contextual emotions. The current study used behavioral methods and electroencephalography ...

    Abstract While previous studies have explored the neurocognitive mechanism of novel word learning under sentential contexts, few studies have probed the potential effects of contextual emotions. The current study used behavioral methods and electroencephalography to elucidate the dynamic influences of contextual emotions while encoding abstract or concrete novel words on subsequent retrieval of the learned meanings. Enhanced N400 and smaller late positive components (LPC) were elicited when encoding abstract words in the positive context. Furthermore, negative contexts were found to hinder both abstract and concrete word learning, while positive contexts had a greater inhibitory effect on learning abstract words than concrete words. Taken together, these findings suggest that the effects of contextual emotions on novel word learning depend on the concreteness of the learned word and occur during the early and late processing stages while mapping abstract and concrete semantic concepts to novel words.
    MeSH term(s) Humans ; Male ; Female ; Electroencephalography ; Evoked Potentials ; Emotions ; Semantics ; Learning
    Language English
    Publishing date 2023-04-06
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 194929-9
    ISSN 1872-7972 ; 0304-3940
    ISSN (online) 1872-7972
    ISSN 0304-3940
    DOI 10.1016/j.neulet.2023.137227
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The complete chloroplast genome sequence of an invasive plant,

    Huang, Yue / Cao, Jingjing / Zhao, Mengxin / Guo, Jianying / Li, Jiamei / Wang, Rui

    Mitochondrial DNA. Part B, Resources

    2024  Volume 9, Issue 3, Page(s) 352–356

    Abstract: Tragopogon ... ...

    Abstract Tragopogon dubius
    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2024.2329668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Bayesian genome-wide TWAS with reference transcriptomic data of brain and blood tissues identified 93 risk genes for Alzheimer's disease dementia.

    Guo, Shuyi / Yang, Jingjing

    medRxiv : the preprint server for health sciences

    2023  

    Abstract: Background: Transcriptome-wide association study (TWAS) is an influential tool for identifying novel genes associated with complex diseases, where their genetic effects may be mediated through transcriptome. TWAS utilizes reference genetic and ... ...

    Abstract Background: Transcriptome-wide association study (TWAS) is an influential tool for identifying novel genes associated with complex diseases, where their genetic effects may be mediated through transcriptome. TWAS utilizes reference genetic and transcriptomic data to estimate genetic effect sizes on expression quantitative traits of target genes (i.e., effect sizes of a broad sense of expression quantitative trait loci, eQTL). These estimated effect sizes are then employed as variant weights in burden gene-based association test statistics, facilitating the mapping of risk genes for complex diseases with genome-wide association study (GWAS) data. However, most existing TWAS of Alzheimer's disease (AD) dementia have primarily focused on
    Methods: We first applied BGW-TWAS to the Genotype-Tissue Expression (GTEx) V8 dataset to estimate
    Results: We identified 37 genes in prefrontal cortex, 55 in cortex, and 51 in whole blood that were significantly associated with AD dementia. By combining BGW-TWAS p-values across these three tissues, we obtained 93 significant risk genes including 29 genes primarily due to
    Conclusion: We applied BGW-TWAS and aggregated Cauchy test methods to integrate both
    Language English
    Publishing date 2023-07-12
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.07.06.23292336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Decreasing acid value of fatty acid ethyl ester products using complex enzymes.

    Li, Yuting / Guo, Jingjing / Sun, Shangde

    Frontiers in bioengineering and biotechnology

    2024  Volume 12, Page(s) 1355009

    Abstract: Recently, enzymatic method has been used to prepare biodiesel using various oils. But the high acid value of the biodiesel product using enzyme as a catalyst has been one issue. In this work, an attempt to reduce the acid value of fatty acid ethyl ester ( ...

    Abstract Recently, enzymatic method has been used to prepare biodiesel using various oils. But the high acid value of the biodiesel product using enzyme as a catalyst has been one issue. In this work, an attempt to reduce the acid value of fatty acid ethyl ester (FAEE) product to satisfy the specified requirement (AV ≤ 0.5 mgKOH/g), a complex enzyme-catalyzed method was used for the ethanolysis of Semen Abutili seed oil (SASO) (AV = 5.5 ± 0.3 mgKOH/g). The effects of various variables (constituents of complex enzyme, type and addition of water removal agent, time, temperature, enzyme addition load, substrate ratio) on the enzymatic reaction were investigated. The optimal reaction conditions were: 1% addition of liquid lipase Eversa
    Language English
    Publishing date 2024-02-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2024.1355009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Polybrominated diphenyl ethers in student dormitory microenvironments: Concentrations, sources, and human exposure.

    Jin, Mantong / Guo, Zhaoxuan / Ye, Nanxi / Sun, Liwei / Guo, Jingjing

    Environmental pollution (Barking, Essex : 1987)

    2024  Volume 350, Page(s) 124010

    Abstract: Microenvironments, such as student dormitories, differ from general residential environments. They are characterized by small spaces, poor air circulation, high personnel densities, and electronic products, such as computers that are turned on for ... ...

    Abstract Microenvironments, such as student dormitories, differ from general residential environments. They are characterized by small spaces, poor air circulation, high personnel densities, and electronic products, such as computers that are turned on for extended periods, leading to increased pollution concentrations. The limited space and poor air circulation reduce migration of contaminants, such as polybrominated diphenyl ethers (PBDEs), making it easier for PBDEs to accumulate. However, few studies have been conducted on small group dwellings, including student dormitory dwellings. We collected dust samples from student dormitories of a university to analyze the characteristics and traceability of PBDEs in dormitory microenvironments. The results showed that PBDE congeners were widely present in university dormitories and the order of median concentration of ∑
    Language English
    Publishing date 2024-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2024.124010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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