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  1. Article ; Online: Feasibility of a Nephrology Faculty Peer Observation of Teaching Pilot Program.

    William, Jeffrey H / Lecker, Stewart H / Cohen, Robert A

    Kidney360

    2023  Volume 4, Issue 6, Page(s) e824–e827

    MeSH term(s) Humans ; Nephrology ; Pilot Projects ; Feasibility Studies ; Faculty ; Staff Development
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Journal Article
    ISSN 2641-7650
    ISSN (online) 2641-7650
    DOI 10.34067/KID.0000000000000138
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  2. Article ; Online: Pattern Recognition versus Pathogenesis: Electrolytes in a Patient with Adrenal Insufficiency.

    Hoenig, Melanie P / Lecker, Stewart H

    Clinical journal of the American Society of Nephrology : CJASN

    2022  Volume 17, Issue 4, Page(s) 585–587

    MeSH term(s) Adrenal Insufficiency/complications ; Adrenal Insufficiency/diagnosis ; Electrolytes ; Humans ; Hyponatremia
    Chemical Substances Electrolytes
    Language English
    Publishing date 2022-03-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.16061221
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  3. Article ; Online: The times they are K+-changin': bringing the potassium curriculum out of the 20th century.

    Hoenig, Melanie P / Lecker, Stewart H / William, Jeffrey H

    Current opinion in nephrology and hypertension

    2023  Volume 33, Issue 2, Page(s) 186–191

    Abstract: Purpose of review: Although most of the current medical education literature has focused on teaching strategies, little attention has been devoted to selecting appropriate course content. Despite elegant descriptions of physiologic mechanisms in recent ... ...

    Abstract Purpose of review: Although most of the current medical education literature has focused on teaching strategies, little attention has been devoted to selecting appropriate course content. Despite elegant descriptions of physiologic mechanisms in recent decades, medical school curricula and students continue to rely on outdated textbooks and certification examination study aids composed to fit an antiquated exam blueprint.
    Recent findings: Advances in our understanding of potassium physiology offer multiple examples of key concepts that deserve to be included in the modern-day renal physiology curriculum, including the relationship of potassium to blood pressure and the potassium 'switch', the aldosterone paradox, and novel pharmacologic agents that target dietary potassium absorption and potassium handling in the kidney.
    Summary: Key advances in our understanding and application of renal physiology to patient care have not been readily integrated into the nephrology curriculum of medical students. Difficult questions remain regarding when new concepts are sufficiently established to be introduced to medical students in the preclinical years.
    MeSH term(s) Humans ; Potassium ; Curriculum ; Education, Medical ; Kidney/physiology ; Students, Medical
    Chemical Substances Potassium (RWP5GA015D)
    Language English
    Publishing date 2023-12-04
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1151092-4
    ISSN 1473-6543 ; 1535-3842 ; 1062-4813 ; 1062-4821
    ISSN (online) 1473-6543 ; 1535-3842
    ISSN 1062-4813 ; 1062-4821
    DOI 10.1097/MNH.0000000000000958
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  4. Article ; Online: Trust the Patient: An Unusual Case of Metabolic Alkalosis.

    Hoenig, Melanie Paige / Lecker, Stewart H

    Clinical journal of the American Society of Nephrology : CJASN

    2021  Volume 16, Issue 5, Page(s) 800–802

    MeSH term(s) Adenoma, Villous/complications ; Adenoma, Villous/diagnosis ; Adenoma, Villous/metabolism ; Aged ; Alkalosis/etiology ; Colonic Neoplasms/complications ; Colonic Neoplasms/diagnosis ; Colonic Neoplasms/metabolism ; Female ; Humans ; Trust
    Language English
    Publishing date 2021-03-16
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.18031120
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  5. Article ; Online: Acid Base Disorders in Cirrhosis.

    Xu, Eric J / Zarm, Ayaa M / Lecker, Stewart H / Hoenig, Melanie P

    Advances in kidney disease and health

    2023  Volume 30, Issue 4, Page(s) 336–342

    Abstract: Metabolic and respiratory acid-base disorders are common in individuals with liver disease and cirrhosis. The most common disorder is respiratory alkalosis, which may be related to dyspnea or respiratory stimulation. Primary metabolic disorders are less ... ...

    Abstract Metabolic and respiratory acid-base disorders are common in individuals with liver disease and cirrhosis. The most common disorder is respiratory alkalosis, which may be related to dyspnea or respiratory stimulation. Primary metabolic disorders are less common. Although the liver plays a role in metabolism of amino acids and generation of acid from dietary sources, it does not play a role in the regulation of pH. Instead, metabolic disorders may arise from alterations in normal metabolism or from medications, particularly diuretics and osmotic laxatives, used in the treatment of these complex patients. Understanding the mechanistic underpinnings of these disorders can aid in the management of individuals with liver disease in the hospital and in outpatient settings.
    MeSH term(s) Humans ; Liver Cirrhosis/complications ; Alkalosis, Respiratory ; Amino Acids ; Antifibrinolytic Agents
    Chemical Substances Amino Acids ; Antifibrinolytic Agents
    Language English
    Publishing date 2023-07-17
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 3156601-7
    ISSN 2949-8139
    ISSN (online) 2949-8139
    DOI 10.1053/j.akdh.2023.04.002
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    Zs.A 4627: Show issues Location:
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  6. Article ; Online: What's Old Is New Again: Harnessing the Power of Original Experiments to Learn Renal Physiology.

    Hoenig, Melanie P / Lecker, Stewart H / William, Jeffrey H

    Advances in chronic kidney disease

    2022  Volume 29, Issue 6, Page(s) 486–492

    Abstract: Although medical schools across the United States have updated their curricula to incorporate active learning techniques, there has been little discussion on the nature of the content presented to students. Here, we share detailed examples of our ... ...

    Abstract Although medical schools across the United States have updated their curricula to incorporate active learning techniques, there has been little discussion on the nature of the content presented to students. Here, we share detailed examples of our experience in using original experiments to lay the groundwork for foundational concepts in renal physiology and pathophysiology. We believe that this approach offers distinct advantages over standard case-based teaching by (1) starting with simple concepts, (2) analyzing memorable visuals, (3) increasing graphical literacy, (4) translating observations to "rules," (5) encouraging critical thinking, and (6) providing historical perspective to the study of medicine. Although we developed this content for medical students, we have found that many of these lessons are also appropriate as foundational concepts for residents and fellows and serve as an excellent springboard for increasingly complex discussions of clinical applications of physiology. The use of original experiments for teaching and learning in renal physiology harnesses skills in critical thinking and provides a solid foundation that will help learners with subsequent case-based learning in the preclerkship curriculum and in the clinical arena.
    MeSH term(s) Humans ; United States ; Curriculum ; Students, Medical ; Thinking
    Language English
    Publishing date 2022-11-10
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1548-5609 ; 1548-5595
    ISSN (online) 1548-5609
    ISSN 1548-5595
    DOI 10.1053/j.ackd.2022.03.006
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  7. Article: More than meets the I(ris): Use of manual urine microscopy to complement automated findings in acute kidney injury.

    Hoenig, Melanie P / Mena, Jose D / Lecker, Stewart H

    Practical laboratory medicine

    2022  Volume 29, Page(s) e00267

    Abstract: Evaluation of patients with acute kidney injury requires comprehensive assessment that includes a urinalysis, which features both semi-quantitative assessment with a urine dipstick and urine microscopy. This process is labor intensive for clinical ... ...

    Abstract Evaluation of patients with acute kidney injury requires comprehensive assessment that includes a urinalysis, which features both semi-quantitative assessment with a urine dipstick and urine microscopy. This process is labor intensive for clinical laboratories, and availability of excellent automated instruments for urinalysis has prompted utilization and acceptance of this strategy by both by laboratories and clinicians. Recently, however, interest in provider performed microscopy has enjoyed a renaissance thanks to both improved microscopy techniques and the endorsement from social media in nephrology. Here, we present two cases of acute kidney injury in which manual microscopy added valuable information to the automated microscopy.
    Language English
    Publishing date 2022-02-07
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2834973-8
    ISSN 2352-5517
    ISSN 2352-5517
    DOI 10.1016/j.plabm.2022.e00267
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  8. Article: RAAS-Blockade in COVID-19: The Ace of Spades?

    Agarwal, Krishna A / Kyriazis, Periklis P / Lecker, Stewart H

    Indian journal of nephrology

    2021  Volume 31, Issue 4, Page(s) 423–424

    Language English
    Publishing date 2021-01-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2134388-3
    ISSN 1998-3662 ; 0971-4065
    ISSN (online) 1998-3662
    ISSN 0971-4065
    DOI 10.4103/ijn.IJN_322_20
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  9. Article ; Online: American Society of Nephrology Kidney TREKS Program.

    Rubin, Molly / Lecker, Stewart H / Ramkumar, Nirupama / Sozio, Stephen M / Hoover, Robert S / Zeidel, Mark L / Ko, Benjamin S

    Journal of the American Society of Nephrology : JASN

    2024  

    Abstract: In response to decreasing numbers of individuals entering into nephrology fellowships, the American Society of Nephrology launched Kidney TREKS (Tutored Research and Education for Kidney Scholars) to stimulate interest in nephrology among medical ... ...

    Abstract In response to decreasing numbers of individuals entering into nephrology fellowships, the American Society of Nephrology launched Kidney TREKS (Tutored Research and Education for Kidney Scholars) to stimulate interest in nephrology among medical students, graduate students, and postdoctoral fellows. The program combines a one-week intensive exposure to kidney physiology with a longitudinal mentorship program at the participants' home institutions. Ten years in, an analysis was conducted to assess its effectiveness. We surveyed participants to assess their opinions regarding nephrology before and after the course and followed them longitudinally to determine their career choices. TREKS applicants who were not selected to participate were used as a comparison group. 381 people participated in the program and 242 completed the survey. After TREKS, both medical students and graduate students showed increased interest in nephrology, with rank scores of 5.6±0.2 pre- to 7.5±0.1 post-course for medical students (mean ± standard deviation, n=189, p=0.001) and 7.3±0.3 to 8.7±0.3 (n=53, p=0.001) for graduate students. In long term follow-up, TREKS medical students chose a nephrology pipeline residency at a higher rate than medical students overall (57% vs. 31%, p=0.01) and TREKS applicants who did not participate (47% vs. 31%, p=0.04). Nephrology fellowship rates for these groups exceeded the general population but did not significantly differ between TREKS participants and applicants. PhD students and postdoctoral TREKS participants had a higher rate of participating in nephrology research compared to TREKS applicants (66% vs. 30%, p=0.01). In summary, the ASN Kidney TREKS program has demonstrated that it can improve interest in nephrology in the short term and increase the number of individuals going into nephrology careers. This long-term effect is most evident in PhD students and postdoctoral participants. Further study is needed to assess the impact of TREKS on enrollment in nephrology fellowship programs.
    Language English
    Publishing date 2024-04-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.0000000000000384
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    Zs.A 3344: Show issues Location:
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  10. Article ; Online: More than meets the I(ris)

    Melanie P. Hoenig / Jose D. Mena / Stewart H. Lecker

    Practical Laboratory Medicine, Vol 29, Iss , Pp e00267- (2022)

    Use of manual urine microscopy to complement automated findings in acute kidney injury

    2022  

    Abstract: Evaluation of patients with acute kidney injury requires comprehensive assessment that includes a urinalysis, which features both semi-quantitative assessment with a urine dipstick and urine microscopy. This process is labor intensive for clinical ... ...

    Abstract Evaluation of patients with acute kidney injury requires comprehensive assessment that includes a urinalysis, which features both semi-quantitative assessment with a urine dipstick and urine microscopy. This process is labor intensive for clinical laboratories, and availability of excellent automated instruments for urinalysis has prompted utilization and acceptance of this strategy by both by laboratories and clinicians. Recently, however, interest in provider performed microscopy has enjoyed a renaissance thanks to both improved microscopy techniques and the endorsement from social media in nephrology. Here, we present two cases of acute kidney injury in which manual microscopy added valuable information to the automated microscopy.
    Keywords Urinalysis ; Acute kidney injury ; Acute interstitial nephritis ; Acute tubular necrosis ; Medicine (General) ; R5-920 ; Chemistry ; QD1-999
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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