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  1. Article ; Online: Effect Analysis of the Venting Direction on Explosion Pressure in LPG Pipelines.

    Bi, Haipu / Cao, Yujie / Mao, Wei / Wang, Kaimin

    ACS omega

    2024  Volume 9, Issue 13, Page(s) 15709–15717

    Abstract: In order to study the effect of the venting direction on explosion pressure in liquefied petroleum gas pipelines, explosion accident scenarios are experimentally tested and numerically simulated in a pipeline model with different explosion venting ... ...

    Abstract In order to study the effect of the venting direction on explosion pressure in liquefied petroleum gas pipelines, explosion accident scenarios are experimentally tested and numerically simulated in a pipeline model with different explosion venting directions. In addition, the effect characteristic is analyzed through the pressure field varying with time and peak pressure varying with the distance. Results show that the pressure in the vertical branch decreases sharply, while the pressure in the horizontal branch does not show an obvious decrease with explosion venting of the vertical branch. However, the pressure decreases obviously in both branches with explosion venting of the horizontal branch, and the biggest reduction of peak pressure of monitoring points is 73.55% compared with that without venting. In addition, large areas of negative pressure appear in both branches with explosion venting of the vertical branch; however, a large area of negative pressure area appears in the horizontal branch with explosion venting of the horizontal branch. What is more, the arrival time of peak pressure in the main pipe of the explosion pipeline is significantly reduced with explosion venting, which is caused by the different generation ways of peak pressure. The effect analysis result of the venting direction on explosion pressure could aid the optimal layout design of LPG pipelines with the location of venting and important facilities as well as with the selection of negative-pressure-resistant material and higher-accuracy sensors.
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.4c00917
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Identification of key candidate genes and pathways in rheumatoid arthritis and osteoarthritis by integrated bioinformatical analysis.

    Huang, Huijing / Dong, Xinyi / Mao, Kaimin / Pan, Wanwan / Nie, Bin'en / Jiang, Lindi

    Frontiers in genetics

    2023  Volume 14, Page(s) 1083615

    Abstract: Rheumatoid arthritis (RA) and osteoarthritis (OA) are the most common joint disorders. Although they have shown analogous clinical manifestations, the pathogenesis of RA and OA are different. In this study, we used the online Gene Expression Omnibus (GEO) ...

    Abstract Rheumatoid arthritis (RA) and osteoarthritis (OA) are the most common joint disorders. Although they have shown analogous clinical manifestations, the pathogenesis of RA and OA are different. In this study, we used the online Gene Expression Omnibus (GEO) microarray expression profiling dataset GSE153015 to identify gene signatures between RA and OA joints. The relevant data on 8 subjects obtained from large joints of RA patients (RA-LJ), 8 subjects obtained from small joints of RA patients (RA-SJ), and 4 subjects with OA were investigated. Differentially expressed genes (DEGs) were screened. Functional enrichment analysis of DEGs including the Gene Ontology terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were identified, which were mainly associated with T cell activation or chemokine activity. Besides, protein-protein interaction (PPI) network analysis was performed, and key modules were identified. Hub genes of RA-LJ and OA groups were screened, they were
    Language English
    Publishing date 2023-02-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1083615
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Prognostic markers of ferroptosis-related long non-coding RNA in lung adenocarcinomas.

    Mao, Kaimin / Tang, Ri / Wu, Yali / Zhang, Zhiyun / Gao, Yuan / Huang, Huijing

    Frontiers in genetics

    2023  Volume 14, Page(s) 1118273

    Abstract: Ferroptosis is a recently established type of iron-dependent programmed cell death. Growing studies have focused on the function of ferroptosis in cancers, including lung adenocarcinoma (LUAD). However, the factors involved in the regulation of ... ...

    Abstract Ferroptosis is a recently established type of iron-dependent programmed cell death. Growing studies have focused on the function of ferroptosis in cancers, including lung adenocarcinoma (LUAD). However, the factors involved in the regulation of ferroptosis-related genes are not fully understood. In this study, we collected data from lung adenocarcinoma datasets of the Cancer Genome Atlas (TCGA-LUAD). The expression profiles of 60 ferroptosis-related genes were screened, and two differentially expressed ferroptosis subtypes were identified. We found the two ferroptosis subtypes can predict clinical outcomes and therapeutic responses in LUAD patients. Furthermore, key long non-coding RNAs (lncRNAs) were screened by single factor Cox and least absolute shrinkage and selection operator (LASSO) based on which co-expressed with the 60 ferroptosis-related genes. We then established a risk score model which included 13 LUAD ferroptosis-related lncRNAs with a multi-factor Cox regression. The risk score model showed a good performance in evaluating the outcome of LUAD. What's more, we divided TCGA-LUAD tumor samples into two groups with high- and low-risk scores and further explored the differences in clinical characteristics, tumor mutation burden, and tumor immune cell infiltration among different LUAD tumor risk score groups and evaluate the predictive ability of risk score for immunotherapy benefit. Our findings provide good support for immunotherapy in LUAD in the future.
    Language English
    Publishing date 2023-02-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1118273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Non-Fourier Heat Conduction of Nano-Films under Ultra-Fast Laser.

    Mao, Yudong / Liu, Shouyu / Liu, Jiying / Yu, Mingzhi / Li, Xinwei / Yang, Kaimin

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 14

    Abstract: The ultra-fast laser heating process of nano-films is characterized by an ultra-short duration and ultra-small space size, in which the classical Fourier law based on the hypothesis of local equilibrium is no longer applicable. Based on the Cattaneo- ... ...

    Abstract The ultra-fast laser heating process of nano-films is characterized by an ultra-short duration and ultra-small space size, in which the classical Fourier law based on the hypothesis of local equilibrium is no longer applicable. Based on the Cattaneo-Vernotte (CV) model and the dual-phase-lag (DPL) model, the two-dimensional analytical solutions of heat conduction in nano-films under ultra-fast laser are obtained using the integral transformation method. The results show that there is a thermal wave phenomenon inside the film, which becomes increasingly evident as the elapse of the lag time of the temperature gradient. Moreover, the wave amplitude in the vertical direction is much larger than that in the horizontal direction of the nano-film. By comparing the numerical result of the two models, it is found that the temperature distribution inside the nano-film based on the DPL model is gentler than that of the CV model. Additionally, the temperature distribution in the two-dimensional solution is lower than that in the one-dimensional solution under the same Knudsen number. In the comparison results of the CV model, the maximum peak difference in the thermal wave reaches 75.08 K when the Knudsen number is 1.0. This demonstrates that the horizontal energy carried by the laser source significantly impacts the temperature distribution within the film.
    Language English
    Publishing date 2023-07-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16144988
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Correction to: Network‑Based Integrated Analysis of Transcriptomic Studies in Dissecting Gene Signatures for LPS‑Induced Acute Lung Injury.

    Cao, Fang / Wang, Chunyan / Long, Danling / Deng, Yujuan / Mao, Kaimin / Zhong, Hua

    Inflammation

    2021  Volume 45, Issue 2, Page(s) 929

    Language English
    Publishing date 2021-11-12
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 434408-x
    ISSN 1573-2576 ; 0360-3997
    ISSN (online) 1573-2576
    ISSN 0360-3997
    DOI 10.1007/s10753-021-01584-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1401: Show issues Location:
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  6. Article: Identification of the Prognostic Significance of Somatic Mutation-Derived LncRNA Signatures of Genomic Instability in Lung Adenocarcinoma.

    Geng, Wei / Lv, Zhilei / Fan, Jinshuo / Xu, Juanjuan / Mao, Kaimin / Yin, Zhengrong / Qing, Wanlu / Jin, Yang

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 657667

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.657667
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Metal-Free Radical Annulation of Oxygen-Containing 1,7-Enynes: Configuration-Selective Synthesis of (

    Mao, Kaimin / Bian, Mouwang / Dai, Lei / Zhang, Jinghang / Yu, Qiuyu / Wang, Chang / Rong, Liangce

    Organic letters

    2020  Volume 23, Issue 1, Page(s) 218–224

    Abstract: A novel strategy for the synthesis of ( ...

    Abstract A novel strategy for the synthesis of (
    Language English
    Publishing date 2020-12-22
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.0c03946
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  8. Article ; Online: Copper-Catalyzed Annulation Reaction of Alkenes and

    Pan, Zhengbing / Mao, Kaimin / Zhu, Guangzhou / Wang, Chang / Zhang, Jinpeng / Rong, Liangce

    The Journal of organic chemistry

    2020  Volume 85, Issue 5, Page(s) 3364–3373

    Abstract: A copper-catalyzed annulation reaction to access a variety of isoxazoles from alkenes and oxazete in situ generated ... ...

    Abstract A copper-catalyzed annulation reaction to access a variety of isoxazoles from alkenes and oxazete in situ generated from
    Language English
    Publishing date 2020-02-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.9b03157
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Ru-Catalyzed δ-Arylation of

    Dai, Lei / Mao, Kaimin / Zhang, Ge / Wang, Chang / Liu, Yun / Rong, Liangce / Zhang, Jinpeng

    The Journal of organic chemistry

    2020  Volume 85, Issue 11, Page(s) 7238–7246

    Abstract: A novel reaction mode and efficient ruthenium-catalyzed Matsuda-Heck-type arylation ... ...

    Abstract A novel reaction mode and efficient ruthenium-catalyzed Matsuda-Heck-type arylation of
    Language English
    Publishing date 2020-05-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.0c00621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Time-Economical Radical Cascade Cyclization/Haloazidation of 1,6-Enynes: Construction of Highly Functional Succinimide Derivatives.

    Gu, Yan / Dai, Lei / Mao, Kaimin / Zhang, Jinghang / Wang, Chang / Zhao, Liming / Rong, Liangce

    Organic letters

    2020  Volume 22, Issue 8, Page(s) 2956–2960

    Abstract: A "time-economical" radical cascade cyclization/haloazidation of 1,6-enynes provides a direct approach to access highly functional succinimide compounds. Moderate to excellent yields along with ... ...

    Abstract A "time-economical" radical cascade cyclization/haloazidation of 1,6-enynes provides a direct approach to access highly functional succinimide compounds. Moderate to excellent yields along with excellent
    Language English
    Publishing date 2020-04-07
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.0c00682
    Database MEDical Literature Analysis and Retrieval System OnLINE

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