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  1. Article ; Online: Combination of radiotherapy and flap reconstruction for cancer treatments (Review).

    Xu, Haonan / Liang, Yuwen / Tang, Wenqiang / Du, Xiaobo

    Molecular and clinical oncology

    2024  Volume 20, Issue 5, Page(s) 34

    Abstract: Flaps are commonly used to repair large tissue defects caused by tumor resection and are often combined with radiotherapy. Relevant explanations for the mechanism underlying the effect of radiotherapy on flaps and the selection of the sequence of flaps ... ...

    Abstract Flaps are commonly used to repair large tissue defects caused by tumor resection and are often combined with radiotherapy. Relevant explanations for the mechanism underlying the effect of radiotherapy on flaps and the selection of the sequence of flaps and radiotherapy plan have emerged. The combination of flap and radiotherapy is most widely used in breast, head and neck cancers, while free flaps are the most widely used. Although, reduction of the incidence of complications of flap reconstruction, prevention of flap reconstruction failure and best integration of flap reconstruction with radiation therapy remains controversial. In the present review, these questions and debates were addressed by reviewing the literature on radiotherapy and flap reconstruction in cancer treatment.
    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2796865-0
    ISSN 2049-9469 ; 2049-9450
    ISSN (online) 2049-9469
    ISSN 2049-9450
    DOI 10.3892/mco.2024.2732
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A papain-based colorimetric catalytic sensing system for immunoassay detection of carcinoembryonic antigen.

    Li, Xiaoqin / Lu, Xiaoxue / Zhang, Linyu / Cai, Zhixiong / Tang, Dianping / Lai, Wenqiang

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2024  Volume 315, Page(s) 124269

    Abstract: A colorimetric immunoassay was built for determination of carcinoembryonic antigen (CEA) based on papain-based colorimetric catalytic sensing system through the use of glucose oxidase (GOx). In the presence of GOx, glucose was catalytically oxidized to ... ...

    Abstract A colorimetric immunoassay was built for determination of carcinoembryonic antigen (CEA) based on papain-based colorimetric catalytic sensing system through the use of glucose oxidase (GOx). In the presence of GOx, glucose was catalytically oxidized to produce H
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2024.124269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Split-type photoelectrochemical immunoassay for sensitive quantification of carcinoembryonic antigen based on target-induced

    Zhang, Jianhui / Tan, Meirong / Chen, Qian / Zhang, Kangyao / Zhou, Qian / Lai, Wenqiang / Tang, Dianping

    Analytical methods : advancing methods and applications

    2024  Volume 16, Issue 13, Page(s) 1901–1907

    Abstract: Carcinoembryonic antigen (CEA), a vital biomarker, plays a significant role in the early diagnosis and prognostic estimation of malignant tumors. In this study, a split-type photoelectrochemical immunoassay for the sensitive quantification of CEA has ... ...

    Abstract Carcinoembryonic antigen (CEA), a vital biomarker, plays a significant role in the early diagnosis and prognostic estimation of malignant tumors. In this study, a split-type photoelectrochemical immunoassay for the sensitive quantification of CEA has been successfully developed based on the target-induced
    MeSH term(s) Carcinoembryonic Antigen/chemistry ; Metal Nanoparticles/chemistry ; Gold/chemistry ; Silver ; Immunoassay/methods
    Chemical Substances Carcinoembryonic Antigen ; Gold (7440-57-5) ; Silver (3M4G523W1G)
    Language English
    Publishing date 2024-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515210-5
    ISSN 1759-9679 ; 1759-9660
    ISSN (online) 1759-9679
    ISSN 1759-9660
    DOI 10.1039/d4ay00248b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Electrospun MoS

    Wu, Sheng / Liu, Qian / Zhang, Wei / Wu, Ruizhe / Tang, Hongping / Ma, Yulin / Xu, Wenqiang / Jiang, Shufang

    Polymers

    2024  Volume 16, Issue 7

    Abstract: As a promising candidate for high-energy-density rechargeable lithium metal batteries, Li/ ... ...

    Abstract As a promising candidate for high-energy-density rechargeable lithium metal batteries, Li/FeS
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16070921
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  5. Article ; Online: Author Correction: Numerical study of ice loads on different interfaces based on cohesive element formulation.

    Xing, Wenqiang / Cong, Shengyi / Ling, Xianzhang / Li, Xinyu / Cheng, Zhihe / Tang, Liang

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 15329

    Language English
    Publishing date 2023-09-15
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-42776-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hard Disk Failure Prediction Based on Blending Ensemble Learning

    Mingyu Zhang / Wenqiang Ge / Ruichun Tang / Peishun Liu

    Applied Sciences, Vol 13, Iss 3288, p

    2023  Volume 3288

    Abstract: As the most widely used storage device today, hard disks are efficient and convenient, but the damage incurred in the event of a failure can be very significant. Therefore, early warnings before hard disk failure, allowing the stored content to be backed ...

    Abstract As the most widely used storage device today, hard disks are efficient and convenient, but the damage incurred in the event of a failure can be very significant. Therefore, early warnings before hard disk failure, allowing the stored content to be backed up and transferred in advance, can reduce many losses. In recent years, an endless stream of research on the prediction of hard disk failure prediction has emerged. The detection accuracy of various methods, from basic machine learning models, such as decision trees and random forests, to deep learning methods, such as BP neural networks and recurrent neural networks, has also been improving. In this paper, based on the idea of blending ensemble learning, a novel failure prediction method combining machine learning algorithms and neural networks is proposed on the publicly available BackBlaze hard disk datasets. The failure prediction experiment is conducted only with S.M.A.R.T., that is, the learned characteristics collected by self-monitoring analysis and reporting technology, which are internally counted during the operation of the hard disk. The experimental results show that this ensemble learning model is able to outperform other independent models in terms of evaluation criterion based on the Matthews correlation coefficient. Additionally, through the experimental results on multiple types of hard disks, an ensemble learning model with high performance on most types of hard disks is found, which solves the problem of the low robustness and generalization of traditional machine learning methods and proves the effectiveness and high universality of this method.
    Keywords hard disk ; failure prediction ; S.M.A.R.T ; ensemble learning ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 006
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Research on the Sound Insulation Performance of Composite Rubber Reinforced with Hollow Glass Microsphere Based on Acoustic Finite Element Simulation

    Xiaocui Yang / Shuai Tang / Xinmin Shen / Wenqiang Peng

    Polymers, Vol 15, Iss 611, p

    2023  Volume 611

    Abstract: The composite rubber reinforced with hollow glass microsphere (HGM) was a promising composite material for noise reduction, and its sound insulation mechanism was studied based on an acoustic finite element simulation to gain the appropriate parameter ... ...

    Abstract The composite rubber reinforced with hollow glass microsphere (HGM) was a promising composite material for noise reduction, and its sound insulation mechanism was studied based on an acoustic finite element simulation to gain the appropriate parameter with certain constraint conditions. The built simulation model included the air domain, polymer domain and inorganic particles domain. The sound insulation mechanism of the composite material was investigated through distributions of the sound pressure and sound pressure level. The influences of the parameters on the sound transmission loss (STL) were researched one by one, such as the densities of the composite rubber and HGM, the acoustic velocities in the polymer and inorganic particle, the frequency of the incident wave, the thickness of the sound insulator, and the diameter, volume ratio and hollow ratio of the HGM. The weighted STL with the 1/3 octave band was treated as the evaluation criterion to compare the sound insulation property with the various parameters. For the limited thicknesses of 1 mm, 2 mm, 3 mm and 4 mm, the corresponding optimal weighted STL of the composite material reached 14.02 dB, 19.88 dB, 22.838 dB and 25.27 dB with the selected parameters, which exhibited an excellent sound insulation performance and could promote the practical applications of the proposed composite rubber reinforced with HGM.
    Keywords composite rubber ; hollow glass microsphere ; acoustic finite element simulation ; sound insulation mechanism ; sound transmission loss ; sound pressure level ; Organic chemistry ; QD241-441
    Subject code 621
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Research on the Sound Insulation Performance of Composite Rubber Reinforced with Hollow Glass Microsphere Based on Acoustic Finite Element Simulation.

    Yang, Xiaocui / Tang, Shuai / Shen, Xinmin / Peng, Wenqiang

    Polymers

    2023  Volume 15, Issue 3

    Abstract: The composite rubber reinforced with hollow glass microsphere (HGM) was a promising composite material for noise reduction, and its sound insulation mechanism was studied based on an acoustic finite element simulation to gain the appropriate parameter ... ...

    Abstract The composite rubber reinforced with hollow glass microsphere (HGM) was a promising composite material for noise reduction, and its sound insulation mechanism was studied based on an acoustic finite element simulation to gain the appropriate parameter with certain constraint conditions. The built simulation model included the air domain, polymer domain and inorganic particles domain. The sound insulation mechanism of the composite material was investigated through distributions of the sound pressure and sound pressure level. The influences of the parameters on the sound transmission loss (STL) were researched one by one, such as the densities of the composite rubber and HGM, the acoustic velocities in the polymer and inorganic particle, the frequency of the incident wave, the thickness of the sound insulator, and the diameter, volume ratio and hollow ratio of the HGM. The weighted STL with the 1/3 octave band was treated as the evaluation criterion to compare the sound insulation property with the various parameters. For the limited thicknesses of 1 mm, 2 mm, 3 mm and 4 mm, the corresponding optimal weighted STL of the composite material reached 14.02 dB, 19.88 dB, 22.838 dB and 25.27 dB with the selected parameters, which exhibited an excellent sound insulation performance and could promote the practical applications of the proposed composite rubber reinforced with HGM.
    Language English
    Publishing date 2023-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15030611
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The mediating role of telomere length in multi-pollutant exposure associated with metabolic syndrome in adults.

    Tang, Weifeng / Zhan, Wenqiang / Chen, Qian

    Environmental science and pollution research international

    2023  Volume 30, Issue 34, Page(s) 82068–82082

    Abstract: Metabolic syndrome is a chronic and complex disease characterized by environmental and genetic factors. However, the underlying mechanisms remain unclear. This study assessed the relationship between exposure to a mixture of environmental chemicals and ... ...

    Abstract Metabolic syndrome is a chronic and complex disease characterized by environmental and genetic factors. However, the underlying mechanisms remain unclear. This study assessed the relationship between exposure to a mixture of environmental chemicals and metabolic syndrome (MetS) and further examined whether telomere length (TL) moderated these relationships. A total of 1265 adults aged > 20 years participated in the study. Data on multiple pollutants (polycyclic aromatic hydrocarbons, phthalates, and metals), MetS, leukocyte telomere length (LTL), and confounders were provided in the 2001-2002 National Health and Nutrition Examination Survey. The correlations between multi-pollutant exposure, TL, and MetS in the males and females were separately assessed using principal component analysis (PCA), logistic and extended linear regression models, Bayesian kernel machine regression (BKMR), and mediation analysis. Four factors were generated in PCA that accounted for 76.2% and 77.5% of the total environmental pollutants in males and females, respectively. The highest quantiles of PC2 and PC4 were associated with the risk of TL shortening (P < 0.05). We observed that the relationship between PC2, PC4, and MetS risk was significant in the participants with median TL levels (P for trend = 0.04 for PC2, and P for trend = 0.01 for PC4). Furthermore, mediation analysis revealed that TL could explain 26.1% and 17.1% of the effects of PC2 and PC4 associated with MetS in males, respectively. The results of BKMR model revealed that these associations were mainly driven by 1-PYE (cPIP = 0.65) and Cd (cPIP = 0.29) in PC2. Meanwhile, TL could explain 17.7% of the mediation effects of PC2 associated with MetS in the females. However, the relationships between pollutants and MetS were sparse and inconsistent in the females. Our findings suggest that the effects of the risk of MetS associated with mixed exposure to multiple pollutants are mediated by TL, and this mediating effect in the males is more pronounced than that in the females.
    MeSH term(s) Telomere ; Environmental Pollutants ; Metabolic Syndrome/epidemiology ; Environmental Pollution ; Humans ; Male ; Female ; Polycyclic Aromatic Hydrocarbons/analysis ; Environmental Exposure/statistics & numerical data ; Nutrition Surveys ; Metals
    Chemical Substances Environmental Pollutants ; Polycyclic Aromatic Hydrocarbons ; Metals
    Language English
    Publishing date 2023-06-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-28017-7
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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  10. Article ; Online: Identify Candidate Genes Associated with the Weight and Egg Quality Traits in Wenshui Green Shell-Laying Chickens by the Copy Number Variation-Based Genome-Wide Association Study.

    Yang, Suozhou / Ning, Chao / Yang, Cheng / Li, Wenqiang / Zhang, Qin / Wang, Dan / Tang, Hui

    Veterinary sciences

    2024  Volume 11, Issue 2

    Abstract: Copy number variation (CNV), as an essential source of genetic variation, can have an impact on gene expression, genetic diversity, disease susceptibility, and species evolution in animals. To better understand the weight and egg quality traits of ... ...

    Abstract Copy number variation (CNV), as an essential source of genetic variation, can have an impact on gene expression, genetic diversity, disease susceptibility, and species evolution in animals. To better understand the weight and egg quality traits of chickens, this paper aimed to detect CNVs in Wenshui green shell-laying chickens and conduct a copy number variation regions (CNVRs)-based genome-wide association study (GWAS) to identify variants and candidate genes associated with their weight and egg quality traits to support related breeding efforts. In our paper, we identified 11,035 CNVRs in Wenshui green shell-laying chickens, which collectively spanned a length of 13.1 Mb, representing approximately 1.4% of its autosomal genome. Out of these CNVRs, there were 10,446 loss types, 491 gain types, and 98 mixed types. Notably, two CNVRs showed significant correlations with egg quality, while four CNVRs exhibited significant associations with body weight. These significant CNVRs are located on chromosome 4. Further analysis identified potential candidate genes that influence weight and egg quality traits, including
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2768971-2
    ISSN 2306-7381 ; 2306-7381
    ISSN (online) 2306-7381
    ISSN 2306-7381
    DOI 10.3390/vetsci11020076
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