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  1. Article ; Online: Psychiatric and neuropsychiatric syndromes and COVID-19.

    Pattni, Vijay / Phillips, Jeffrey / Saha, Rajnish

    The lancet. Psychiatry

    2020  Volume 7, Issue 8, Page(s) 664

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Syndrome
    Keywords covid19
    Language English
    Publishing date 2020-07-23
    Publishing country England
    Document type Letter ; Comment
    ISSN 2215-0374
    ISSN (online) 2215-0374
    DOI 10.1016/S2215-0366(20)30299-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Psychiatric and neuropsychiatric syndromes and COVID-19

    Pattni, Vijay / Phillips, Jeffrey / Saha, Rajnish

    The Lancet Psychiatry

    2020  Volume 7, Issue 8, Page(s) 664

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2215-0366
    DOI 10.1016/s2215-0366(20)30299-6
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Meckel's diverticulum in an adult: an obscure presentation of gastrointestinal bleeding.

    Pattni, Vijay / Wright, Kathryn / Marden, Peter / Terlevich, Ana

    BMJ case reports

    2016  Volume 2016

    Abstract: A 17-year-old boy, with a background of haemophilia A, presented to hospital with an episode of brisk and painless per rectal (PR) bleeding. Initial investigation with gastroscopy and colonoscopy revealed no source of bleeding. Examination of the small ... ...

    Abstract A 17-year-old boy, with a background of haemophilia A, presented to hospital with an episode of brisk and painless per rectal (PR) bleeding. Initial investigation with gastroscopy and colonoscopy revealed no source of bleeding. Examination of the small bowel including MRI, CT angiogram and capsule endoscopy revealed no abnormalities. Double balloon enteroscopy (DBE) from an antegrade position was attempted, with no abnormalities noted. The symptoms persisted and DBE was attempted again from a retrograde approach and a diverticulum was subsequently noted. Laparoscopic surgery was performed identifying a diverticulum as the source of bleeding, 110 cm from the ileocaecal valve, which is more proximal than is normally seen. Histological examination revealed a Meckel's diverticulum. The case described here, although more unusual in adults, demonstrates that complete visualisation of the small bowel remains challenging and that newer modalities of enteroscopy including DBE can help aid in the diagnosis of obscure gastrointestinal bleeding.
    MeSH term(s) Adolescent ; Double-Balloon Enteroscopy/methods ; Gastrointestinal Hemorrhage/etiology ; Gastrointestinal Hemorrhage/surgery ; Hemophilia A/complications ; Humans ; Laparoscopy/methods ; Male ; Meckel Diverticulum/diagnosis ; Meckel Diverticulum/etiology ; Meckel Diverticulum/surgery ; Treatment Outcome
    Language English
    Publishing date 2016-04-28
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2015-213852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Device-assisted enteroscopy in the UK: description of a large tertiary case series under conscious sedation.

    Pattni, Vijay / Tate, David J / Terlevich, Ana / Marden, Peter / Hughes, Steve

    Frontline gastroenterology

    2017  Volume 9, Issue 2, Page(s) 122–128

    Abstract: Objective: Device-assisted enteroscopy (DAE) has developed rapidly, particularly with the advent of double-balloon enteroscopy (DBE). This study reports a case series from a UK tertiary centre for DAE across two modalities-DBE and spiral enteroscopy (SE) ...

    Abstract Objective: Device-assisted enteroscopy (DAE) has developed rapidly, particularly with the advent of double-balloon enteroscopy (DBE). This study reports a case series from a UK tertiary centre for DAE across two modalities-DBE and spiral enteroscopy (SE)-under conscious sedation.
    Design: Retrospective observational study of 257 enteroscopy procedures from 2008 to 2014. Data were collected on demographics, indications, diagnosis, sedation requirements, duration, complications, tolerance, therapy performed and completion rate. Procedures were performed under conscious sedation using a combination of midazolam, pethidine and fentanyl in a solely outpatient setting.
    Results: Obscure gastrointestinal bleeding (OGIB) was the commonest indication for DAE (n=164, 63.8%). Overall, yield of DAE was 47.2% and varied significantly across the indications (p=0.003). There was a greater likelihood of positive findings if the indication was polyposis syndrome (75%), abnormal capsule endoscopy (67%) or OGIB (53%) and in older patients (mean age normal exam 60.3 vs abnormal exam 67.9 years, p<0.001). Higher mean doses of midazolam were used for DBE from above (5.4 mg, SD 2.24) and SE (5.6 mg, SD 2.9) to DBE from below (4.4 mg, SD 1.8). No serious complications were recorded. Tolerance of DAE was good with the majority (240/257, 93.4%) of procedures tolerated with comfort scores 0 or 1. Therapy was performed in 121/257 (47.1%) of procedures. The strongest predictor indications for therapy to be performed at DAE were abnormal capsule endoscopy (88.9%) and occult gastrointestinal (GI) bleeding (54.9%). Completion rates were higher in DBEb (91.8%) compared to DBEa (76.5%) and SE (81.6%).
    Conclusion: DAE under conscious sedation is safe and well tolerated. DAE has a high yield if performed for recognised indications and may be safely used to provide therapy where a diagnosis has been made using other modalities.
    Language English
    Publishing date 2017-08-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2521857-8
    ISSN 2041-4137
    ISSN 2041-4137
    DOI 10.1136/flgastro-2017-100842
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: An unusual presentation of an infected vallecular cyst presenting as supraglottitis.

    Pattni, Vijay / Porter, Graham / Omakobia, Eugene

    BMJ case reports

    2013  Volume 2013

    Abstract: A 50-year-old gentleman presented to the emergency department with a 24 h history of stridor, dysphonia, dysphagia and vomiting. On examination, the patient had fever and tachycardic. There was no palpable cervical lymphadenopathy. Flexible nasendoscopy ... ...

    Abstract A 50-year-old gentleman presented to the emergency department with a 24 h history of stridor, dysphonia, dysphagia and vomiting. On examination, the patient had fever and tachycardic. There was no palpable cervical lymphadenopathy. Flexible nasendoscopy and lateral neck x-ray revealed soft tissue swelling around the epiglottis. The swelling subsided with conservative management of intravenous antibiotics and steroids, only to later reveal a vallecular cyst, which was confirmed on microlaryngoscopy. The cyst was subsequently deroofed and sent for biopsy. Histological examination revealed an infected, benign vallecular cyst consisting of a squamous epithelium with underlying lymphoid tissue. In adults, vallecular cysts are usually asymptomatic, but can become infected and initiate acute supraglottitis, potentially leading to life-threatening airway obstruction. The case described here, although rare, highlights how early definitive diagnosis and management of vallecular cysts can lead to significantly improved patient outcomes.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Biopsy ; Cysts/diagnosis ; Cysts/drug therapy ; Diagnosis, Differential ; Drug Therapy, Combination ; Humans ; Laryngeal Diseases/diagnosis ; Laryngeal Diseases/drug therapy ; Laryngoscopy ; Male ; Middle Aged ; Steroids/therapeutic use ; Supraglottitis/diagnosis ; Supraglottitis/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Steroids
    Language English
    Publishing date 2013-04-22
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2013-009180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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