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Article ; Online: Worm Migration Tracks in Paragonimiasis.

Okumura, Nobumasa / Morioka, Shinichiro / Tanaka, Mio / Ohmagari, Norio

2024

Language	English
Publishing date	2024-02-05
Publishing country	Japan
Document type	Journal Article
ZDB-ID	32371-8
ISSN	1349-7235 ; 0021-5120 ; 0918-2918
ISSN (online)	1349-7235
ISSN	0021-5120 ; 0918-2918
DOI	10.2169/internalmedicine.3179-23
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Article ; Online: A case of confirmed pre-symptomatic transmission of mpox.

Kubo, Taketo / Hayakawa, Kayoko / Akiyama, Yutaro / Morioka, Shinichiro / Ohmagari, Norio

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

2023 Volume 29, Issue 10, Page(s) 1008–1009

Abstract: Mpox virus is known to be transmissible from the onset of clinical manifestations. We report the first case in Japan of a man who contracted mpox through close contact with an individual with pre-symptomatic infection. Given that transmission before ... ...

Abstract	Mpox virus is known to be transmissible from the onset of clinical manifestations. We report the first case in Japan of a man who contracted mpox through close contact with an individual with pre-symptomatic infection. Given that transmission before symptom onset has recently been reported from various countries, the importance of prophylaxis for reducing the risk of infection and controlling the disease should be emphasized.
MeSH term(s)	Male ; Humans ; Mpox (monkeypox) ; Japan
Language	English
Publishing date	2023-06-29
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	1355399-9
ISSN	1437-7780 ; 1341-321X
ISSN (online)	1437-7780
ISSN	1341-321X
DOI	10.1016/j.jiac.2023.06.018
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Article ; Online: Exacerbations of Idiopathic Systemic Capillary Leak Syndrome following BNT162b2 mRNA COVID-19 Vaccine (Pfizer-BioNTech).

Akiyama, Yutaro / Inagaki, Takeshi / Morioka, Shinichiro / Kusano, Eiji / Ohmagari, Norio

Internal medicine (Tokyo, Japan)

2023 Volume 62, Issue 13, Page(s) 2013–2017

Abstract: A Japanese man experienced three episodes of hypovolemic shock and was diagnosed with systemic capillary leak syndrome (SCLS). He developed SCLS exacerbation 2 days after receiving a second dose of the Pfizer-BioNTech BNT162b2 mRNA COVID-19 vaccine, 1 ... ...

Abstract	A Japanese man experienced three episodes of hypovolemic shock and was diagnosed with systemic capillary leak syndrome (SCLS). He developed SCLS exacerbation 2 days after receiving a second dose of the Pfizer-BioNTech BNT162b2 mRNA COVID-19 vaccine, 1 year after the third episode. After fluid therapy and albumin administration, we initiated terbutaline and theophylline prophylaxis for SCLS. A literature review revealed that SCLS attacks often occur 1-2 days after the second COVID-19 vaccination. Patients with a history of SCLS should avoid COVID-19 vaccination and be carefully monitored for 1-2 days if they receive the vaccine.
MeSH term(s)	Humans ; Male ; BNT162 Vaccine ; Capillary Leak Syndrome/etiology ; Capillary Leak Syndrome/diagnosis ; Capillary Leak Syndrome/drug therapy ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Terbutaline
Chemical Substances	BNT162 Vaccine ; COVID-19 Vaccines ; Terbutaline (N8ONU3L3PG)
Language	English
Publishing date	2023-04-21
Publishing country	Japan
Document type	Review ; Journal Article
ZDB-ID	32371-8
ISSN	1349-7235 ; 0021-5120 ; 0918-2918
ISSN (online)	1349-7235
ISSN	0021-5120 ; 0918-2918
DOI	10.2169/internalmedicine.1682-23
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Article ; Online: Scrub Typhus with Respiratory Symptoms.

Taguchi, Maho / Morioka, Shinichiro / Ishikane, Masahiro / Ohmagari, Norio

Internal medicine (Tokyo, Japan)

2020 Volume 59, Issue 18, Page(s) 2339–2340

Language	English
Publishing date	2020-06-15
Publishing country	Japan
Document type	Journal Article
ZDB-ID	32371-8
ISSN	1349-7235 ; 0021-5120 ; 0918-2918
ISSN (online)	1349-7235
ISSN	0021-5120 ; 0918-2918
DOI	10.2169/internalmedicine.4268-19
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Article ; Online: Epidemiology of post-COVID conditions beyond 3 years and factors associated with their persistence longer than 2 years: A cross-sectional study.

Morioka, Shinichiro / Nikaido, Mio / Tsuzuki, Shinya / Kutsuna, Satoshi / Saito, Sho / Hayakawa, Kayoko / Sugiyama, Masaya / Ohmagari, Norio

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

2024

Abstract: Objective: This study aimed to investigate the epidemiology of post-coronavirus disease 2019 (COVID-19) conditions (PCCs) beyond 3 years and identify factors associated with their persistence longer than 2 years.: Study design: Cross-sectional ... ...

Abstract	Objective: This study aimed to investigate the epidemiology of post-coronavirus disease 2019 (COVID-19) conditions (PCCs) beyond 3 years and identify factors associated with their persistence longer than 2 years. Study design: Cross-sectional questionnaire-based survey. Methods: We surveyed patients who had recovered from COVID-19 and visited our institution from February 2020 to November 2021. Demographic and clinical data and information on the presence and duration of PCCs were obtained. We identified factors associated with the persistence of PCCs longer than 2 years using multivariate linear regression analyses. Results: Among 935 patients surveyed, 407 completed the survey. Among them, 360 patients had mild disease in the acute phase. The proportions of participants with at least one symptom at 1, 2, and 3 years after symptom onset or COVID-19 diagnosis were 33.2%, 29.8%, and 5.7%, respectively. The numbers of participants with and without any residual symptoms 2 years after the onset of COVID-19 were 87 and 193, respectively. After multivariate adjustment, persistence of PCCs longer than 2 years was associated with lower body mass index, presence of any underlying medical conditions, and number of symptoms lasting for more than 1 month ≥ 5. Conclusions: The prevalence of PCCs decreased 2 years after symptom onset or COVID-19 diagnosis. We also identified factors associated with PCC persistence longer than 2 years, which could help primary care physicians and patients with PCCs predict the duration of PCCs and better understand their natural history, thus reducing patients' anxiety about their duration.
Language	English
Publishing date	2024-02-11
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1355399-9
ISSN	1437-7780 ; 1341-321X
ISSN (online)	1437-7780
ISSN	1341-321X
DOI	10.1016/j.jiac.2024.02.009
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Article ; Online: Long COVID: current status in Japan and knowledge about its molecular background.

Matsunaga, Akihiro / Tsuzuki, Shinya / Morioka, Shinichiro / Ohmagari, Norio / Ishizaka, Yukihito

Global health & medicine

2022 Volume 4, Issue 2, Page(s) 83–93

Abstract: Even after recovering from coronavirus disease 2019 (COVID-19), patients can experience prolonged complaints, referred to as "long COVID". Similar to reports in Caucasians, a follow-up study in Japan revealed that fatigue, dyspnea, cough, anosmia/ ... ...

Abstract	Even after recovering from coronavirus disease 2019 (COVID-19), patients can experience prolonged complaints, referred to as "long COVID". Similar to reports in Caucasians, a follow-up study in Japan revealed that fatigue, dyspnea, cough, anosmia/dysgeusia, and dyssomnia are common symptoms. Although the precise mode of long COVID remains elusive, multiple etiologies such as direct organ damage by infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), autoimmunity, prolonged inflammatory reactions, and psychiatric impairment seem to be involved. Notably, SARS-CoV-2 is neurotropic, and viral RNA and proteins are continuously detectable in multiple organs, including the brain. Viral proteins exert a number of different toxic effects on cells, suggesting that persistent infection is a key element for understanding long COVID. Here, we first reviewed the current status of long COVID in Japan, and then summarized literature that help us understand the molecular background of the symptoms. Finally, we discuss the feasibility of vaccination as a treatment for patients with long COVID.
Language	English
Publishing date	2022-05-04
Publishing country	Japan
Document type	Journal Article ; Review
ISSN	2434-9194
ISSN (online)	2434-9194
DOI	10.35772/ghm.2022.01013
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Article ; Online: Task-specific fear influences abnormal trunk motor coordination in workers with chronic low back pain: a relative phase angle analysis of object-lifting.

Fujii, Ren / Imai, Ryota / Shigetoh, Hayato / Tanaka, Shinichiro / Morioka, Shu

BMC musculoskeletal disorders

2022 Volume 23, Issue 1, Page(s) 161

Abstract: Background: Pain-related fear influences impaired trunk movement (e.g., limited movement of range and velocity), but it is unclear how fear relates to trunk motor coordination (e.g., a more "in-phase" upper-lower trunk motion pattern). We conducted the ... ...

Abstract	Background: Pain-related fear influences impaired trunk movement (e.g., limited movement of range and velocity), but it is unclear how fear relates to trunk motor coordination (e.g., a more "in-phase" upper-lower trunk motion pattern). We conducted the present study to: (1) identify the motor coordination pattern of the in-phase upper-lower lumbar movements during the lifting, and (2) determine how pain-related fear is related to the trunk coordination pattern in workers with chronic low back pain (CLBP). Methods: We examined 31 male workers with CLBP (CLBP group) and 20 healthy controls with no history of CLBP (HC group). The movement task was lifting a box, the weight of which was 10, 30%, or 50% of the subject's body weight. We used a 3D motion capture system to calculate the mean absolute relative phase angle (MARP) angle as an index of coordination and the mean deviation phase (DP) as an index of variability. We used a numerical rating scale to assess the subjects' task-specific fear. Results: The MARP angle during trunk extension movement in the 50% condition was significantly decreased in the CLBP group compared to the HCs; i.e., the upper lumbar movement was more in-phase with the lower lumbar movement. The hierarchical multiple regression analysis results demonstrated that a decreased MARP angle was associated with high task-specific fear. Conclusions: A more 'in-phase' upper-lower lumbar movement pattern was predicted by task-specific fear evoked when performing a work-related activity. Our findings suggest that an intervention for task-specific fear may be necessary to improve an individual's impaired trunk motor coordination.
MeSH term(s)	Biomechanical Phenomena/physiology ; Fear/physiology ; Humans ; Lifting ; Low Back Pain/complications ; Low Back Pain/diagnosis ; Male ; Movement/physiology ; Torso
Language	English
Publishing date	2022-02-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2041355-5
ISSN	1471-2474 ; 1471-2474
ISSN (online)	1471-2474
ISSN	1471-2474
DOI	10.1186/s12891-022-05118-x
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Article: Changes in task-specific fear of movement and impaired trunk motor control by pain neuroscience education and exercise: A preliminary single-case study of a worker with low back pain.

Fujii, Ren / Imai, Ryota / Shigetoh, Hayato / Tanaka, Shinichiro / Morioka, Shu

SAGE open medical case reports

2022 Volume 10, Page(s) 2050313X221131162

Abstract: We report a case (a worker with low back pain) who was provided patient education and therapeutic exercise, and we performed a detailed kinematic analysis of his work-related activity over time. The subjects were one 28-year-old male worker with low back ...

Abstract	We report a case (a worker with low back pain) who was provided patient education and therapeutic exercise, and we performed a detailed kinematic analysis of his work-related activity over time. The subjects were one 28-year-old male worker with low back pain. In addition, to clearly identify impaired trunk movement during work-related activity in the low back pain subject, 20 age-matched healthy males (control group) were also included as a comparison subject. He received pain neurophysiology education and exercise instruction. We analyzed the subject's trunk movement pattern during a lifting task examined by a three-dimensional-motion capture system. In addition, task-specific fear that occurred during the task was assessed by the numerical rating scale. The assessment was performed at the baseline phase (4 data points), the intervention phase (8 data points), and the follow-up phase (8 data points), and finally at 3 and 8 months after the follow-up phase. No intervention was performed in the control group; they underwent only one kinematic evaluation at baseline. As a result, compared to the control group, the low back pain subject had slower trunk movement velocity (peak trunk flexion velocity = 50.21 deg/s, extension velocity = -47.61 deg/s), and his upper-lower trunk segments indicated an in-phase motion pattern (mean absolute relative phase = 15.59 deg) at baseline. The interventions reduced his pain intensity, fear of movement, and low back pain-related disability; in addition, his trunk velocity was increased (peak trunk flexion velocity = 82.89 deg/s, extension velocity = -77.17 deg/s). However, the in-phase motion pattern of his trunk motor control remained unchanged (mean absolute relative phase = 16.00 deg). At 8 months after the end of the follow-up, the subject's in-phase motion pattern remained (mean absolute relative phase = 13.34 deg) and his pain intensity had increased. This report suggests that if impaired trunk motor control remains unchanged after intervention, as in the course of the low back pain subject, it may eventually be related to a recurrence of low back pain symptoms.
Language	English
Publishing date	2022-10-24
Publishing country	England
Document type	Case Reports
ZDB-ID	2736953-5
ISSN	2050-313X
ISSN	2050-313X
DOI	10.1177/2050313X221131162
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Article ; Online: Kinematic analysis of movement impaired by generalization of fear of movement-related pain in workers with low back pain.

Fujii, Ren / Imai, Ryota / Tanaka, Shinichiro / Morioka, Shu

PloS one

2021 Volume 16, Issue 9, Page(s) e0257231

Abstract: Purpose: To identify impaired trunk movement during work-related activity in individuals with low back pain (LBP) and investigate whether abnormalities were caused by generalized fear of movement-related pain.: Methods: This cross-sectional study was ...

Abstract	Purpose: To identify impaired trunk movement during work-related activity in individuals with low back pain (LBP) and investigate whether abnormalities were caused by generalized fear of movement-related pain. Methods: This cross-sectional study was conducted at a hospital in Japan. We recruited 35 participants with LBP (LBP group; 26 males, 9 females) and 20 healthy controls (HC group) via posters at our hospital. The task required lifting an object. We used a 3D motion capture system to calculate the peak angular velocity of trunk flexion and extension during a lifting task. Pain-related factors for the LBP group were assessed using the visual analogue scale (VAS) for pain intensity over the past 4 weeks and during the task, the Tampa Scale for Kinesiophobia (TSK), the Pain Catastrophizing Scale (PCS), and the Pain Anxiety Symptoms Scale-20 (PASS-20). We compared kinematic variables between groups with a generalized linear mixed model and investigated the relationship between kinematic variables, VAS scores, and psychological factors by performing a mediation analysis. Results: The peak angular velocity of trunk extension showed significant main effects on the group factors (LBP group vs. HC group) and their interactions; the value of the kinematic variable was lower at Trial 1 in the LBP group. No LBP participant reported pain during the experiment. The mediation analysis revealed that the relationship between the VAS score for pain intensity over the past 4 weeks and the peak angular velocity of trunk extension in the first trial was completely mediated by the TSK (complete mediation model, 95% bootstrapped CI: 0.07-0.56). Conclusion: Individuals with LBP had reduced trunk extension during a lifting task. Generalized fear of movement-related pain may contribute to such impaired trunk movement. Our findings suggest that intervention to ameliorate fear of movement may be needed to improve LBP-associated disability.
MeSH term(s)	Biomechanical Phenomena ; Case-Control Studies ; Cross-Sectional Studies ; Fear ; Female ; Generalization, Psychological ; Humans ; Imaging, Three-Dimensional ; Japan/epidemiology ; Low Back Pain/physiopathology ; Low Back Pain/psychology ; Male ; Motion ; Movement ; Pain Measurement ; Range of Motion, Articular ; Surveys and Questionnaires ; Visual Analog Scale
Language	English
Publishing date	2021-09-17
Publishing country	United States
Document type	Journal Article
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0257231
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Beau's Lines and Leukonychia in a COVID-19 Patient.

Ide, Satoshi / Morioka, Shinichiro / Inada, Makoto / Ohmagari, Norio

Internal medicine (Tokyo, Japan)

2020 Volume 59, Issue 24, Page(s) 3259

MeSH term(s)	Aged ; COVID-19/complications ; COVID-19/epidemiology ; Humans ; Hypopigmentation/diagnosis ; Hypopigmentation/etiology ; Male ; Nail Diseases/congenital ; Nail Diseases/diagnosis ; Nail Diseases/etiology ; Nails/pathology ; Pandemics ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-11-02
Publishing country	Japan
Document type	Case Reports ; Journal Article
ZDB-ID	32371-8
ISSN	1349-7235 ; 0021-5120 ; 0918-2918
ISSN (online)	1349-7235
ISSN	0021-5120 ; 0918-2918
DOI	10.2169/internalmedicine.6112-20
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