LIVIVO - Search results -

Search results

Result 1 - 10 of total 1176

Search options

Article: A dysregulated calcium homeostasis as the earliest pathological sign in stem cell-derived Parkinson's disease neurons?

Prakash, Nilima

2023 Volume 19, Issue 7, Page(s) 1421–1422

Language	English
Publishing date	2023-11-08
Publishing country	India
Document type	Journal Article
ZDB-ID	2388460-5
ISSN	1876-7958 ; 1673-5374
ISSN (online)	1876-7958
ISSN	1673-5374
DOI	10.4103/1673-5374.387986
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Internet-based cognitive behaviour therapy for the prevention, treatment and relapse prevention of eating disorders: A systematic review and meta-analysis.

Hamid, Nilima

PsyCh journal

2023 Volume 13, Issue 1, Page(s) 5–18

Abstract: Eating disorders (EDs) are undertreated worldwide. In the UK the lag between recognition of symptoms and treatment ranges from about 15 months to in excess of 2 years. Internet-based cognitive behaviour therapy (ICBT) could be a viable alternative to ... ...

Abstract	Eating disorders (EDs) are undertreated worldwide. In the UK the lag between recognition of symptoms and treatment ranges from about 15 months to in excess of 2 years. Internet-based cognitive behaviour therapy (ICBT) could be a viable alternative to face-to-face cognitive behaviour therapy (CBT) that avoids the negative impacts of delayed interventions. Based on evidence from randomised controlled trials (RCTs), this systematic review investigated the efficacy of minimally guided self-help ICBT, without face-to-face therapy, for the prevention, treatment and relapse prevention of all types of EDs in adults. The electronic databases MEDLINE, PsychINFO, CENTRAL, Scopus, and Web of Science were searched between 1991 and 2021. Inclusion criteria specified RCTs with ICBT versus inactive comparison groups. The Cochrane Risk of Bias Tool-2 was used for quality assessments. Qualitative synthesis and meta-analyses were conducted. Findings typically showed medium significant beneficial effect sizes for prevention studies ranging from (-0.31 [95% CI: -0.57, -0.06] to -0.47 [95% CI: -0.82, -0.11]) and generally large effect sizes for the treatment studies ranging from (-0.30 [95% CI: -0.57, -0.03] to -1.11 [95% CI: -1.47, -0.75]). Relapse prevention studies yielded mainly small non-significant beneficial effects with significant effect sizes of (-0.29 [95% CI: -0.56, -0.03] and -0.43 [95% CI: -0.70, -0.16]). Only the treatment studies reached clinical significance and cognitive symptoms improved more than behavioural symptoms. ICBT appears to be efficacious for the prevention, treatment and relapse prevention of eating disorders with treatment interventions being the most beneficial. However, the evidence base is very small, particularly for treatment and relapse prevention, indicating the need for more high-quality RCTs.
MeSH term(s)	Adult ; Humans ; Secondary Prevention ; Cognitive Behavioral Therapy ; Feeding and Eating Disorders/prevention & control ; Internet
Language	English
Publishing date	2023-12-17
Publishing country	Australia
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	2717141-3
ISSN	2046-0260 ; 2046-0252
ISSN (online)	2046-0260
ISSN	2046-0252
DOI	10.1002/pchj.715
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6992: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Oral health in individuals with bleeding disorders: A systematic review and meta-analysis.

Bhadauria, Upendra Singh / Purohit, Bharathi / Nilima, Nilima / Priya, Harsh

Haemophilia : the official journal of the World Federation of Hemophilia

2024

Abstract: Background: Individuals with bleeding disorders have been reported to have a number of oral health issues due to varying conditions. A comprehensive evaluation of the different oral health conditions has not been carried out in the past. This systematic ...

Abstract	Background: Individuals with bleeding disorders have been reported to have a number of oral health issues due to varying conditions. A comprehensive evaluation of the different oral health conditions has not been carried out in the past. This systematic review and meta-analysis was carried out to collate and critically analyse existing research, and provide a comprehensive overview of the current state of knowledge on oral health. Methods: A comprehensive search was conducted in electronic databases, including PubMed, Scopus and Embase, in October 2023. No restriction on time frame or language was applied. The risk of bias for cross-sectional studies was assessed using the Agency for Healthcare Research and Quality (AHRQ) tool, and case control studies were assessed using the New Castle Ottawa Scale (NOS). Results: Twenty-two articles were included in the final analysis with a total sample size of 2422 subjects. Of the 22 articles assessed, nine quantitative assessments were included in the Meta analysis. Pooled data analysis was carried out. A total of 13 studies reported medium risk whereas the remaining nine studies showed low risk of bias. The weighted mean DMFT scores in individuals with bleeding disorders were found to be 2.43 [0.62. 4.24], mean dmft was 2.79 [1.05, 4.53] and mean OHI-S was reported to be 1.79 [1.00, 2.57], respectively. Conclusion: The findings emphasize that these individuals have fair oral hygiene and lower dmft/DMFT scores. Oral bleeding emerged as an important oral health component to be cautiously dealt with particularly during the stages of exfoliation/shedding.
Language	English
Publishing date	2024-04-17
Publishing country	England
Document type	Journal Article
ZDB-ID	1229713-6
ISSN	1365-2516 ; 1351-8216 ; 1355-0691
ISSN (online)	1365-2516
ISSN	1351-8216 ; 1355-0691
DOI	10.1111/hae.15009
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4249: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 450: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review.

Mishra, Biswamohan / Sudheer, Pachipala / Agarwal, Ayush / Nilima, Nilima / Srivastava, Madakasira Vasantha Padma / Vishnu, Venugopalan Y

Brain sciences

2024 Volume 14, Issue 1

Abstract: There is a growing awareness of the significance of using minimum clinically important differences (MCIDs) in stroke research. An MCID is the smallest change in an outcome measure that is considered clinically meaningful. This review is the first to ... ...

Abstract	There is a growing awareness of the significance of using minimum clinically important differences (MCIDs) in stroke research. An MCID is the smallest change in an outcome measure that is considered clinically meaningful. This review is the first to provide a comprehensive summary of various scales and patient-reported outcome measures (PROMs) used in stroke research and their MCID values reported in the literature, including a concise overview of the concept of and methods for determining MCIDs in stroke research. Despite the controversies and limitations surrounding the estimation of MCIDs, their importance in modern clinical trials cannot be overstated. Anchor-based and distribution-based methods are recommended for estimating MCIDs, with patient self-evaluation being a crucial component in capturing the patient's perspective on their health. A combination of methods can provide a more comprehensive understanding of the clinical relevance of treatment effects, and incorporating the patient's perspective can enhance the care of stroke patients.
Language	English
Publishing date	2024-01-13
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2651993-8
ISSN	2076-3425
ISSN	2076-3425
DOI	10.3390/brainsci14010080
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: A Systematic Review of the Statistical Methods Adopted for Analyzing Follow-Up Data in Cohort Multiple Randomized Controlled Trial.

Narzari, Hina / Nilima, Nilima / Vishnu, Venugopalan Y / Khan, Maroof A / Gupta, Anu / Srivastava, Vasantha Padma

Cureus

2024 Volume 16, Issue 1, Page(s) e51558

Abstract: Background: The cohort multiple randomized controlled trial (cmRCT) can tackle some of the weaknesses of an RCT which has triggered the interest of researchers considerably over time. Several challenges persist regarding the methods of analyzing such ... ...

Abstract	Background: The cohort multiple randomized controlled trial (cmRCT) can tackle some of the weaknesses of an RCT which has triggered the interest of researchers considerably over time. Several challenges persist regarding the methods of analyzing such valued data. The paucity of international recommendations concerning the statistical methods for analyzing trial data has led to a variety of strategies further complicating the result comparison. Our aim was to review the different cmRCT analysis methods since cmRCT was first proposed in 2010. Methodology: A search for full-length studies presenting statistical analysis of the data collected adopting a cmRCT design was conducted on PubMed, Cochrane Library, EMBASE, JSTOR, Scopus, MEDLINE, and ClinicalTrials.gov. Results: Out of 186 studies screened, we selected 22 for the full-text screening and 11 were found eligible for data extraction. All 11 studies were conducted in high-income countries, reflecting the design being underutilized in other settings. All of the studies were found to have used intention-to-treat (ITT) analysis with four of them utilizing instrumental variables (IV) analysis or a complier average causal effect (CACE). Randomization was noted often to be interchangeably used for random selection. Sample size calculation was not clearly specified in the majority of the studies. Conclusion: Clarity regarding the distinction between an RCT and a cmRCT is warranted. The fundamental difference in design, which leads to certain biases that need to be taken care of by adopting IV or CACE analysis, has to be understood before taking up a cmRCT.
Language	English
Publishing date	2024-01-03
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.51558
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Psychometric Properties of the Oral Health Values Scale and Cultural Adaptation in the Indian Population.

Bhadauria, Upendra S / Purohit, Bharathi / Nilima, Nilima / Priya, Harsh / Hansraj, Waidya N / Singh, Sarveshwari

Cureus

2024 Volume 16, Issue 2, Page(s) e53942

Abstract: Aim: The Oral Health Values Scale is a multidimensional instrument that identifies and measures a person's values related to oral health. This scale has been validated in American respondents. This study aims to evaluate the adaptability and validity of ...

Abstract	Aim: The Oral Health Values Scale is a multidimensional instrument that identifies and measures a person's values related to oral health. This scale has been validated in American respondents. This study aims to evaluate the adaptability and validity of the Oral Health Values Scale in the Hindi language (H-OHVS). Methodology: A total of 240 adults participated in the study that was carried out from July to November 2022. An offline one-to-one survey was carried out to collect data by an investigator blinded to the study protocol. The translation and testing of the OHVS were carried out based on the cross-cultural adaptation guidelines of the American Academy of Orthopedic Surgeons (AAOS) Evidence-Based Medicine Committee. The content validity was assessed by an expert panel. Construct validity was analyzed through Exploratory Factor Analysis (EFA), utilizing principal component analysis with varimax rotation. The internal consistency of the Hindi version of OHVS was evaluated using Cronbach's alpha. Results: The results showed that H-OHVS had an Item-level Construct Validity Index (I-CVI) ranging from 0.82 to 1.00. Two components, compliance and hesitance, were formed on H-OHVS accounting for 63.91% of the cumulative variance. The resulting model fit indices on confirmatory factor analysis presented an adequate fit to the data. The overall Cronbach's alpha coefficient for H-OHVS (α = 0.868) presents excellent internal consistency. Conclusions: The study findings provide a certain degree of evidence in favor of this scale and establish the Oral Health Values Scale (OHVS) as a psychometrically sound measure.
Language	English
Publishing date	2024-02-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.53942
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Geographic variation and factors associated with anemia among under-fives in India

Jeetendra Yadav / Nilima Nilima

Clinical Epidemiology and Global Health, Vol 9, Iss , Pp 261-

A multilevel approach

2021 Volume 268

Abstract: This study investigates the individual, household, and community-level determinants of anemia and to report the locations with poor anemia status among under-fives. A secondary data derived from the fourth round of the National Family Health Survey ... ...

Abstract	This study investigates the individual, household, and community-level determinants of anemia and to report the locations with poor anemia status among under-fives. A secondary data derived from the fourth round of the National Family Health Survey conducted in India in the period 2015–2016 was used. The study focused on the percentage of under-fives who had anemia across India. A choropleth map was obtained to present the distribution of anemia among under-fives in India. A multilevel logistic regression model was used to investigate the factors associated with anemia among under-fives. Stata and R software were used for the analysis. The age of the child, size of child at birth, birth interval, mother's age at the time of birth, mother's and father's education, religion, social group, wealth quintile, and region of residence are significant predictors of the childhood anemia. Communally underprivileged children are highly likely to be anemic as compared to those in other areas requiring special attention. The occurrence of childhood anemia was highest in Central India followed by North, Union Territories, East, West, and South of India. In addition to the biological naivety of young mothers, being from a communally underprivileged group also affects health outcomes among under-fives. A consistent effort on increasing the education level of women in India along with a well-planned awareness program is needed to enable women in making informed decisions towards the health outcome of children. These programs must also focus the incentives of delaying first birth until the mother is 25.
Keywords	Anemia ; U-5s ; Multilevel ; Spatial ; India ; Public aspects of medicine ; RA1-1270
Subject code	950
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Bridging the gap between statistical significance and clinical relevance: A systematic review of minimum clinically important difference (MCID) thresholds of scales reported in movement disorders research.

Mishra, Biswamohan / Sudheer, Pachipala / Rajan, Roopa / Agarwal, Ayush / Srivastava, M V Padma / Nilima, Nilima / Vishnu, Venugopalan Y

Heliyon

2024 Volume 10, Issue 5, Page(s) e26479

Abstract: Background: Minimum clinically important difference : Objectives: To provide a comprehensive summary of MCID thresholds of various symptom severity scales reported in movement disorder.: Methods: We conducted systematic review of the literature ... ...

Abstract	Background: Minimum clinically important difference Objectives: To provide a comprehensive summary of MCID thresholds of various symptom severity scales reported in movement disorder. Methods: We conducted systematic review of the literature and included studies of one or more movement disorders, and reporting MCID scales. Results: 2763 reports were screened. Final review included 32 studies. Risk of bias (RoB) assessment showed most studies were of good quality. Most commonly evaluated scale was Unified Parkinson's Disease Rating Scale (UPDRS) (11 out of 32). Four studies assessing MDS-UPDRS had assessed its different sub-parts, reporting a change of 2.64,3.05,3.25 and 0.9 points to detect clinically meaningful improvement and 2.45,2.51,4.63 and 0.8 points to detect clinically meaningful worsening, for the Part I, II, III and IV, respectively. For Parts II + III, I + II + III and I + II + III + IV, MCID thresholds reported for clinically meaningful improvement were 5.73, 4.9, 6.7 and 7.1 points respectively; while those for clinically meaningful worsening were 4.7, 4.2, 5.2 and 6.3 points, respectively. MCID thresholds reported for other scales included Abnormal Involuntary Movement Scale (AIMS), Toronto Western Spasmodic Torticollis Rating Scale (TWSRS), and Burke-Fahn-Marsden Dystonia Scale (BFMD). Conclusion: This review summarizes all the MCID thresholds currently reported in Movement disorders research and provides a comprehensive resource for future trials, highlighting the need for standardized and validated MCID scales in movement disorder research.
Language	English
Publishing date	2024-02-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e26479
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Supernumerary teeth

Chhavi Jain / Nilima Sharma

Acta Medica International, Vol 10, Iss 2, Pp 155-

Case series with their planned management

2023 Volume 159

Abstract: Introduction: Supernumerary teeth are extra teeth to normal dental formula. They are developmental anomalies which may have multiple etiologies. They may or may not erupt in the oral cavity and are mostly diagnosed incidentally. Case Reports: This is the ...

Abstract	Introduction: Supernumerary teeth are extra teeth to normal dental formula. They are developmental anomalies which may have multiple etiologies. They may or may not erupt in the oral cavity and are mostly diagnosed incidentally. Case Reports: This is the presentation of case series of seven such different types of supernumerary teeth. Among these cases, the treatment of two cases has been shown along with their photographs. Conclusion: Their most common form is mesiodens which are commonly found in the maxillary anterior region creating unesthetic appearance for which patient seeks treatment. If not diagnosed and managed on time they can create complications such as malalignment, diastema, crowding, noneruption, delayed, or altered eruption of permanent tooth. This case series is an attempt to showcase the deleterious effect of supernumerary teeth and their varied clinical presentation along with their plan of management.
Keywords	extra teeth ; hyperdontia ; mesiodens ; diastema ; polydontia ; supernumerary tooth ; Medicine ; R
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Insilico

Girdhar, Neha / Yadav, Vikas / Kumari, Nilima / Subbarao, Naidu / Krishnamachari, Annangarachari

Journal of biomolecular structure & dynamics

2024 , Page(s) 1–12

Abstract: The current trend in biomedical research is on prioritizing infections based on multidrug resistance. ...

Abstract	The current trend in biomedical research is on prioritizing infections based on multidrug resistance.
Language	English
Publishing date	2024-02-26
Publishing country	England
Document type	Journal Article
ZDB-ID	49157-3
ISSN	1538-0254 ; 0739-1102
ISSN (online)	1538-0254
ISSN	0739-1102
DOI	10.1080/07391102.2024.2321511
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2093: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito