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  1. Article ; Online: Dual Antiplatelet Therapy for the Acute Management and Long-term Secondary Prevention of Ischemic Stroke and Transient Ischemic Attack, An Updated Review.

    Chan, Bernard P L / Wong, Lily Y H / Tan, Benjamin Y Q / Yeo, Leonard L L / Venketasubramanian, Narayanaswamy

    Journal of cardiovascular development and disease

    2024  Volume 11, Issue 2

    Abstract: To improve the efficacy over antiplatelet monotherapy, dual antiplatelet therapy (DAPT) has been increasingly adopted in the management of non-cardioembolic stroke. For minor ischemic stroke and high-risk transient ischemic attack, the aspirin- ... ...

    Abstract To improve the efficacy over antiplatelet monotherapy, dual antiplatelet therapy (DAPT) has been increasingly adopted in the management of non-cardioembolic stroke. For minor ischemic stroke and high-risk transient ischemic attack, the aspirin-clopidogrel combination is now recommended for acute short-term treatment, whereas aspirin-ticagrelor combination may be considered in selected patients, especially those with resistance to clopidogrel. For long-term stroke prevention, aspirin-dipyridamole combination has been used as an alternative to antiplatelet monotherapy, and aspirin or clopidogrel combined with cilostazole may be prescribed for added protection in high-risk patients. In this paper, we review the development of DAPT from a historical perspective and describe the findings from major clinical trials published up until the end of 2023. Using the 2021 American Heart Association guideline for secondary stroke prevention as a basis for our recommendations, we further discuss areas of controversy and more recent developments to provide an updated review for clinicians to consider in their daily practice.
    Language English
    Publishing date 2024-01-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd11020048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effect of Anticoagulation Duration on Stroke Incidence in Asian Patients With Left Ventricular Thrombus.

    Goh, Fang Qin / Leow, Aloysius S T / Ho, Jamie S Y / Tan, Benjamin Y Q / Yeo, Leonard L L / Sia, Ching-Hui

    The American journal of cardiology

    2023  Volume 191, Page(s) 141–143

    MeSH term(s) Humans ; Incidence ; Thrombosis/drug therapy ; Thrombosis/epidemiology ; Thrombosis/etiology ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control ; Blood Coagulation ; Anticoagulants/therapeutic use
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2022.12.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui IV Zs.73: Show issues Location:
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  3. Article ; Online: Short Cuts to Improve Stroke Outcomes by Prehospital Triage: Modeling the Cost of Taking a Longer Time.

    Yeo, Leonard L L / Bhogal, Pervinder / Tan, Benjamin Y Q

    Stroke

    2020  Volume 51, Issue 11, Page(s) 3192–3194

    MeSH term(s) Brain Ischemia ; Humans ; Stroke/diagnosis ; Stroke/therapy ; Triage ; United States
    Language English
    Publishing date 2020-10-07
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.120.032486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 448: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article: Air Pollution and Ischaemic Stroke.

    Ho, Jamie S Y / Jou, Eric / Tan, Benjamin Y Q / Sharma, Vijay K

    Annals of Indian Academy of Neurology

    2022  Volume 25, Issue Suppl 1, Page(s) S26–S34

    Abstract: Air pollution is a significant contributor of cardiovascular diseases, including ischaemic stroke (IS), with substantial mortality and morbidity. However, associations between air pollution and IS remain unclear. Limited data are available on the ... ...

    Abstract Air pollution is a significant contributor of cardiovascular diseases, including ischaemic stroke (IS), with substantial mortality and morbidity. However, associations between air pollution and IS remain unclear. Limited data are available on the relationship between IS and individual air pollutants. In this systematic review, we present an overview of the current literature about various individual ambient air pollutants that are believed to contribute towards incidence of hospitalization and mortality related to IS.
    Language English
    Publishing date 2022-05-03
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.aian_1130_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Impact of Safety Culture Domains on Burnout of Health Care Workers During COVID-19 in Singapore: A Multigroup Structural Equation Modeling Analysis.

    Chen, Ken Xy / Lee, Charmaine / Kanneganti, Abhiram / Lim, Lucas J H / Tan, Melanie / Chua, Ying Xian / Sia, Ching-Hui / Sim, Kang / Ooi, Shirley B S / Tan, Benjamin Y Q / Tan, Li Feng

    Asia-Pacific journal of public health

    2023  Volume 35, Issue 8, Page(s) 583–585

    MeSH term(s) Humans ; COVID-19 ; Singapore/epidemiology ; Latent Class Analysis ; Health Personnel ; Burnout, Professional/epidemiology ; Burnout, Psychological ; Safety Management ; Surveys and Questionnaires
    Language English
    Publishing date 2023-09-11
    Publishing country China
    Document type Journal Article
    ZDB-ID 1025444-4
    ISSN 1941-2479 ; 1010-5395
    ISSN (online) 1941-2479
    ISSN 1010-5395
    DOI 10.1177/10105395231197902
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2802: Show issues Location:
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  6. Article: Gut Microbiota and Stroke.

    Tan, Benjamin Y Q / Paliwal, Prakash R / Sharma, Vijay K

    Annals of Indian Academy of Neurology

    2020  Volume 23, Issue 2, Page(s) 155–158

    Abstract: Ischemic stroke remains a significant health problem, which is expected to increase owing to an aging population. A considerable proportion of stroke patients suffer from gastrointestinal complications, including dysphagia, gastrointestinal hemorrhage, ... ...

    Abstract Ischemic stroke remains a significant health problem, which is expected to increase owing to an aging population. A considerable proportion of stroke patients suffer from gastrointestinal complications, including dysphagia, gastrointestinal hemorrhage, and constipation. Often, these complications adversely affect stroke outcomes. Recent research postulates the role of "brain-gut axis" in causing gut microbiota dysbiosis and various complications and outcomes. In this review, we present our current understanding about the interaction between commensal gut microbiome and brain in determining the course of stroke.
    Language English
    Publishing date 2020-02-25
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_483_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Genetics in Ischemic Stroke: Current Perspectives and Future Directions.

    Zhang, Ka / Loong, Shaun S E / Yuen, Linus Z H / Venketasubramanian, Narayanaswamy / Chin, Hui-Lin / Lai, Poh San / Tan, Benjamin Y Q

    Journal of cardiovascular development and disease

    2023  Volume 10, Issue 12

    Abstract: Ischemic stroke is a heterogeneous condition influenced by a combination of genetic and environmental factors. Recent advancements have explored genetics in relation to various aspects of ischemic stroke, including the alteration of individual stroke ... ...

    Abstract Ischemic stroke is a heterogeneous condition influenced by a combination of genetic and environmental factors. Recent advancements have explored genetics in relation to various aspects of ischemic stroke, including the alteration of individual stroke occurrence risk, modulation of treatment response, and effectiveness of post-stroke functional recovery. This article aims to review the recent findings from genetic studies related to various clinical and molecular aspects of ischemic stroke. The potential clinical applications of these genetic insights in stratifying stroke risk, guiding personalized therapy, and identifying new therapeutic targets are discussed herein.
    Language English
    Publishing date 2023-12-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd10120495
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  8. Article ; Online: Rhabdomyolysis: An Unusual Cause of Scrotal and Abdominal Distention.

    Choe, Rachel / Tan, Benjamin Y Q / Lim, Russell Boonchai / Soong, John Tshon Yit

    The American journal of medicine

    2021  Volume 135, Issue 5, Page(s) 586–588

    MeSH term(s) Humans ; Male ; Rhabdomyolysis/diagnosis ; Rhabdomyolysis/etiology ; Scrotum
    Language English
    Publishing date 2021-12-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2021.11.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.289: Show issues Location:
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  9. Article ; Online: The road to achieving herd immunity: factors associated with Singapore residents' uptake and hesitancy of the COVID-19 vaccination.

    Tan, Li Feng / Huak, Chan Yiong / Siow, Isabel / Tan, Angel Justina / Venugopalan, Preetha Menon / Premkumar, Arthi / Seetharaman, Santhosh Kumar / Tan, Benjamin Y Q

    Expert review of vaccines

    2022  Volume 21, Issue 4, Page(s) 561–567

    Abstract: Objective: Achieving high vaccination rates is key to containing the coronavirus disease 2019 (COVID-19). This study evaluated the factors associated with uptake of the COVID-19 vaccine.: Methods: Six hundred and seventy-six respondents were surveyed ...

    Abstract Objective: Achieving high vaccination rates is key to containing the coronavirus disease 2019 (COVID-19). This study evaluated the factors associated with uptake of the COVID-19 vaccine.
    Methods: Six hundred and seventy-six respondents were surveyed online between May and June 2021. Data on demographics, perception of the COVID-19 pandemic, and vaccine willingness and hesitancy factors were collected.
    Results: Approximately 54.6% of the respondents had received the COVID-19 vaccination. Age (p = 0.001), males (OR 1.7, 95% CI 1.1-2.6, p = 0.026), ethnicity (p = 0.004), occupation (p = 0.003)), working in healthcare (OR 6.1, 95% CI 2.8-13.2, p < 0.001), smoking (OR 3.3, 95% CI 1.3-8.8, p = 0.014), seeing vaccination as a social responsibility (OR 3.8, 95% CI 1.2-12.0, p = 0.022) and believing the vaccine is important to end the COVID-19 pandemic (OR 2.7, 95% CI 1.1-6.1, p = 0.020) were associated with greater vaccination uptake.
    Conclusion: Social responsibility and well-being of collective society are important values associated with vaccine uptake in an Asian society. Understanding factors behind vaccine uptake can help advise public health measures and strategies to achieve high levels of vaccination.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Cross-Sectional Studies ; Humans ; Immunity, Herd ; Male ; Pandemics ; Singapore/epidemiology ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-01-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2181284-6
    ISSN 1744-8395 ; 1476-0584
    ISSN (online) 1744-8395
    ISSN 1476-0584
    DOI 10.1080/14760584.2022.2021883
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    Zs.A 6077: Show issues Location:
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  10. Article ; Online: Headaches Due to Personal Protective Equipment During COVID-19 Pandemic: A Comment.

    Goh, Yihui / Ong, Jonathan J Y / Bharatendu, Chandra / Tan, Benjamin Y Q / Sharma, Vijay K

    Headache

    2020  Volume 60, Issue 7, Page(s) 1446–1447

    MeSH term(s) COVID-19 ; Cross-Sectional Studies ; Headache/epidemiology ; Health Personnel ; Humans ; Pandemics ; Personal Protective Equipment ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-17
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 410130-3
    ISSN 1526-4610 ; 0017-8748
    ISSN (online) 1526-4610
    ISSN 0017-8748
    DOI 10.1111/head.13879
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    Zs.B 539: Show issues Location:
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