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  1. Article ; Online: Dark skies before the storm: The Chronos syndrome.

    Geoffroy, Pierre A

    Bipolar disorders

    2023  Volume 25, Issue 7, Page(s) 608–609

    MeSH term(s) Humans ; Bipolar Disorder
    Language English
    Publishing date 2023-09-25
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1472242-2
    ISSN 1399-5618 ; 1398-5647
    ISSN (online) 1399-5618
    ISSN 1398-5647
    DOI 10.1111/bdi.13380
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Insomnie et troubles psychiatriques.

    Maruani, Julia / Geoffroy, Pierre A

    La Revue du praticien

    2024  Volume 74, Issue 3, Page(s) 285–290

    Abstract: INSOMNIA AND PSYCHIATRIC DISORDERS. Insomnia is frequent in psychiatric disorders. In particular, insomnia can be a risk factor, as well as a comorbid condition, or a symptom and an early sign of psychiatric disorders. Insomnia may emerge during any ... ...

    Title translation Insomnia and psychiatric disorders.
    Abstract INSOMNIA AND PSYCHIATRIC DISORDERS. Insomnia is frequent in psychiatric disorders. In particular, insomnia can be a risk factor, as well as a comorbid condition, or a symptom and an early sign of psychiatric disorders. Insomnia may emerge during any stage of illness. It includes prodromal, first episode, acute, recurrence, and even remission stages, thereby being associated with a worse course of illness. Insomnia increased symptom severity, relapses or recurrences, and increased suicidal risk. Thus, insomnia is an important modifiable risk factor to prevent psychiatric disorders and/or achieve and maintain remission. Thereby insomnia evaluation and management should be a priority in psychiatric cares. Indeed, it has been demonstrated that targeting insomnia can not only improve insomnia itself but also have a positive impact on the trajectory of psychiatric disorders.
    MeSH term(s) Humans ; Sleep Initiation and Maintenance Disorders/diagnosis ; Sleep Initiation and Maintenance Disorders/epidemiology ; Sleep Initiation and Maintenance Disorders/therapy ; Mental Disorders/complications ; Mental Disorders/diagnosis ; Mental Disorders/epidemiology ; Psychotherapy ; Risk Factors
    Language French
    Publishing date 2024-03-29
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.433: Show issues Location:
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  3. Book: Pierre de Coubertin

    Navacelle, Geoffroy de

    sa vie par l'image

    ([Textes choisis / Pierre de Coubertin; Suppl.])

    1986  

    Author's details par Geoffroy de Navacelle
    Series title [Textes choisis / Pierre de Coubertin; Suppl.]
    Keywords 1863-1937 ; Bildband ; Biografie ; Coubertin, Pierre <<de>>
    Size 96 Seiten: überwiegend Illustrationen
    Publisher Weidmann; Zürich [u.a.]
    Document type Book
    HBZ-ID HT003135179
    ISBN 3-296-18004-4 ; 978-3-296-18004-5
    Database Central Library of Sport Science of the German Sport University Cologne

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  4. Book: Pierre de Courbertin

    Navacelle, Geoffroy de

    sa vie par l'image

    1986  

    Institution International Olympic Committee
    Author's details Geoffroy de Navacelle. Comité International Olympique
    Size 96 S, überwiegend Ill
    Publisher Weidmann
    Publishing place Zurich u.a
    Document type Book
    ISBN 3296180044 ; 9783296180045
    Database Former special subject collection: coastal and deep sea fishing

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  5. Article ; Online: How are you dreaming? A very simple question to screen for suicide risk.

    Geoffroy, Pierre Alexis

    Bipolar disorders

    2023  Volume 25, Issue 4, Page(s) 341

    MeSH term(s) Humans ; Bipolar Disorder ; Suicide
    Language English
    Publishing date 2023-04-09
    Publishing country Denmark
    Document type Letter
    ZDB-ID 1472242-2
    ISSN 1399-5618 ; 1398-5647
    ISSN (online) 1399-5618
    ISSN 1398-5647
    DOI 10.1111/bdi.13325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Multi-Level Processes and Retina-Brain Pathways of Photic Regulation of Mood.

    Maruani, Julia / Geoffroy, Pierre A

    Journal of clinical medicine

    2022  Volume 11, Issue 2

    Abstract: Light exerts powerful biological effects on mood regulation. Whereas the source of photic information affecting mood is well established at least via intrinsically photosensitive retinal ganglion cells (ipRGCs) secreting the melanopsin photopigment, the ... ...

    Abstract Light exerts powerful biological effects on mood regulation. Whereas the source of photic information affecting mood is well established at least via intrinsically photosensitive retinal ganglion cells (ipRGCs) secreting the melanopsin photopigment, the precise circuits that mediate the impact of light on depressive behaviors are not well understood. This review proposes two distinct retina-brain pathways of light effects on mood: (i) a suprachiasmatic nucleus (SCN)-dependent pathway with light effect on mood via the synchronization of biological rhythms, and (ii) a SCN-independent pathway with light effects on mood through modulation of the homeostatic process of sleep, alertness and emotion regulation: (1) light directly inhibits brain areas promoting sleep such as the ventrolateral preoptic nucleus (VLPO), and activates numerous brain areas involved in alertness such as, monoaminergic areas, thalamic regions and hypothalamic regions including orexin areas; (2) moreover, light seems to modulate mood through orexin-, serotonin- and dopamine-dependent pathways; (3) in addition, light activates brain emotional processing areas including the amygdala, the nucleus accumbens, the perihabenular nucleus, the left hippocampus and pathways such as the retina-ventral lateral geniculate nucleus and intergeniculate leaflet-lateral habenula pathway. This work synthetizes new insights into the neural basis required for light influence mood.
    Language English
    Publishing date 2022-01-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11020448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Sleep Immune Cross Talk and Insomnia.

    Akkaoui, Marine Ambar / Palagini, Laura / Geoffroy, Pierre A

    Advances in experimental medicine and biology

    2023  Volume 1411, Page(s) 263–273

    Abstract: Sleep and immunity have bidirectional relationships. In this chapter, we review the links between sleep and immunity, focusing on immune changes occurring in the insomnia disorder. During physiological sleep, there is a decrease of pro-inflammatory ... ...

    Abstract Sleep and immunity have bidirectional relationships. In this chapter, we review the links between sleep and immunity, focusing on immune changes occurring in the insomnia disorder. During physiological sleep, there is a decrease of pro-inflammatory cytokines (IL-1, IL-6 and TNF-α) and a decrease of anti-inflammatory cytokines (IL-4, IL-10). Examinations of ratios of pro-inflammatory and anti-inflammatory cytokines allow to identify rather a pro-inflammatory activity at the beginning of the night and confirm then anti-inflammatory during the second part of the night. Immune cells, as NK-cells, decrease in the blood, due to their migration to secondary lymphoid organs, but their activity increases. Inversely, a short sleep duration appears associated with increased inflammatory processes and increased risk of infection.Only few studies have investigated changes in immunity in patients with insomnia disorder. These studies suggest that insomnia disorder is related to deregulation of the immune system, with an increase in the level of pro-inflammatory cytokines and change in rate of secretion and a decrease in the level of lymphocyte. Insomnia treatments, particularly cognitive behavioral therapy (CBT-I), seems to have a restorative effect not only on sleep, but also on the associated inflammation. Melatonin also seems to reduce inflammation in patients suffering from insomnia disorder.More studies are necessary to better understand the pathophysiology of changes in immune system in patients suffering from insomnia disorders and their clinical implications.
    MeSH term(s) Humans ; Sleep Initiation and Maintenance Disorders/therapy ; Sleep/physiology ; Cytokines ; Cognitive Behavioral Therapy ; Inflammation
    Chemical Substances Cytokines
    Language English
    Publishing date 2023-03-22
    Publishing country United States
    Document type Review ; Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-981-19-7376-5_12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Clock Genes and Light Signaling Alterations in Bipolar Disorder: When the Biological Clock Is Off.

    Geoffroy, Pierre A

    Biological psychiatry

    2018  Volume 84, Issue 11, Page(s) 775–777

    MeSH term(s) ARNTL Transcription Factors ; Biological Clocks ; Bipolar Disorder ; CLOCK Proteins ; Humans ; Neuronal Plasticity
    Chemical Substances ARNTL Transcription Factors ; CLOCK Proteins (EC 2.3.1.48)
    Language English
    Publishing date 2018-11-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 209434-4
    ISSN 1873-2402 ; 0006-3223
    ISSN (online) 1873-2402
    ISSN 0006-3223
    DOI 10.1016/j.biopsych.2018.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 720: Show issues Location:
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  9. Article ; Online: Multi-Level Processes and Retina–Brain Pathways of Photic Regulation of Mood

    Julia Maruani / Pierre A. Geoffroy

    Journal of Clinical Medicine, Vol 11, Iss 448, p

    2022  Volume 448

    Abstract: Light exerts powerful biological effects on mood regulation. Whereas the source of photic information affecting mood is well established at least via intrinsically photosensitive retinal ganglion cells (ipRGCs) secreting the melanopsin photopigment, the ... ...

    Abstract Light exerts powerful biological effects on mood regulation. Whereas the source of photic information affecting mood is well established at least via intrinsically photosensitive retinal ganglion cells (ipRGCs) secreting the melanopsin photopigment, the precise circuits that mediate the impact of light on depressive behaviors are not well understood. This review proposes two distinct retina–brain pathways of light effects on mood: (i) a suprachiasmatic nucleus (SCN)-dependent pathway with light effect on mood via the synchronization of biological rhythms, and (ii) a SCN-independent pathway with light effects on mood through modulation of the homeostatic process of sleep, alertness and emotion regulation: (1) light directly inhibits brain areas promoting sleep such as the ventrolateral preoptic nucleus (VLPO), and activates numerous brain areas involved in alertness such as, monoaminergic areas, thalamic regions and hypothalamic regions including orexin areas; (2) moreover, light seems to modulate mood through orexin-, serotonin- and dopamine-dependent pathways; (3) in addition, light activates brain emotional processing areas including the amygdala, the nucleus accumbens, the perihabenular nucleus, the left hippocampus and pathways such as the retina–ventral lateral geniculate nucleus and intergeniculate leaflet–lateral habenula pathway. This work synthetizes new insights into the neural basis required for light influence mood
    Keywords light ; light therapy ; mood ; suprachiasmatic nuclei (SCN) ; Medicine ; R
    Subject code 535
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article ; Online: Dual Orexin Receptor Antagonists and Suicide Risk: Findings From the WHO Spontaneous Reporting Database.

    Salvo, Francesco / Micoulaud-Franchi, Jean-Arthur / Palagini, Laura / Geoffroy, Pierre A

    The Journal of clinical psychiatry

    2023  Volume 84, Issue 6

    MeSH term(s) Humans ; Orexin Receptor Antagonists ; Disease Susceptibility ; Violence ; Suicide ; World Health Organization ; Orexins
    Chemical Substances Orexin Receptor Antagonists ; Orexins
    Language English
    Publishing date 2023-09-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 716287-x
    ISSN 1555-2101 ; 0160-6689
    ISSN (online) 1555-2101
    ISSN 0160-6689
    DOI 10.4088/JCP.23br14923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 247: Show issues

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