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  1. Article ; Online: Progress of researches on inducing hepatic stellate cell ferroptosis for treatment of liver fibrosis

    SUN Lijie, HAO Dandan

    Jichu yixue yu linchuang, Vol 44, Iss 1, Pp 108-

    2024  Volume 113

    Abstract: Emerging evidence suggests that ferroptosis, an iron-dependent form of regulated cell death, plays a critical role in the genesis of liver fibrosis through inducing hepatic stellate cell (HSC) ferroptosis to inhibit liver fibrosis or inducing hepatic ... ...

    Abstract Emerging evidence suggests that ferroptosis, an iron-dependent form of regulated cell death, plays a critical role in the genesis of liver fibrosis through inducing hepatic stellate cell (HSC) ferroptosis to inhibit liver fibrosis or inducing hepatic ferroptosis to potentiates liver fibrosis. Pharmacologically targeting at ferroptosis with its inducers can slow down the progression of liver fibrosis in vitro and in vivo model. This review suggests that pharmacological induction of HSC ferroptosis might be used as a potential novel targeted therapy for the treatment of liver fibrosis.
    Keywords liver fibrosis|hepatic stellate cell|ferroptosis ; Medicine ; R
    Language Chinese
    Publishing date 2024-01-01T00:00:00Z
    Publisher Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Long-Life Zn Anode Enabled with Complexing Ability of a Benign Electrolyte Additive.

    Yu, Dandan / Niu, Huanle / Tian, Tian / Yang, Wenyan / Sun, Dongfei

    The journal of physical chemistry letters

    2024  Volume 15, Issue 14, Page(s) 3843–3850

    Abstract: The development of aqueous zinc ion batteries (AZIBs) is hindered by several problems, including Zn dendrite/corrosion, side reactions, and hydrogen evolution reaction (HER). Herein, trisodium citrate (NaCit) additive is introduced into the ... ...

    Abstract The development of aqueous zinc ion batteries (AZIBs) is hindered by several problems, including Zn dendrite/corrosion, side reactions, and hydrogen evolution reaction (HER). Herein, trisodium citrate (NaCit) additive is introduced into the ZnSO
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7185
    ISSN (online) 1948-7185
    DOI 10.1021/acs.jpclett.4c00626
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Analysis on the characteristics and relationships of lower limbs strength and power of sailors in different positions and levels.

    Sun, Kaiyang / Pan, Dandan

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0289273

    Abstract: Hikers and trapeze sailors are two main Olympic groups based on their specific role during sail racing. This study was to analyze the characteristics and relationships of lower limbs strength and power of hikers and trapeze sailors with different levels. ...

    Abstract Hikers and trapeze sailors are two main Olympic groups based on their specific role during sail racing. This study was to analyze the characteristics and relationships of lower limbs strength and power of hikers and trapeze sailors with different levels. Forty-five hikers and trapeze sailors were divided into high-level and low-level groups, respectively. The isokinetic dynamometer was used to measure sailors' lower limbs strength. Concentric and eccentric peak torque (PT) were measured for hamstrings and quadriceps at 60°/s, and isometric knee extensions at 45° knee flexion (0° = full extension). The counter movement jump (CMJ) was performed by Kistler to reflect sailors' lower limbs power. The results showed the hikers had higher quadriceps isometric PT, and male hikers had higher concentric and eccentric PT compared to trapeze sailors (p<0.05). For female sailors, the quadriceps' concentric, eccentric and isometric PT of high-level group were higher than low-level group' (p<0.05). The sailors' conventional and functional H/Q ratio ranged from 0.44 to 0.56 and 0.52 to 0.65, respectively. High-level and low-level groups had no difference in CMJ, which was moderately to strongly correlated with the isokinetic strength (r ranging 0.50-0.81, p<0.01). These findings suggest that long-term training can induce specificity in lower limbs strength of sailors. Hikers have better quadriceps isometric strength compared to trapeze sailors. The quadriceps concentric and eccentric PT can be used as parameters to distinguish between high-level and low-level sailors, but CMJ cannot.
    MeSH term(s) Female ; Male ; Humans ; Military Personnel ; Lower Extremity ; Quadriceps Muscle ; Exercise Therapy ; Hamstring Muscles
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0289273
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  4. Article ; Online: Human monkeypox virus: Epidemiologic review and research progress in diagnosis and treatment.

    Sun, Yanhong / Nie, Wenjian / Tian, Dandan / Ye, Qing

    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

    2024  Volume 171, Page(s) 105662

    Abstract: Monkeypox virus (MPXV) is responsible for causing a zoonotic disease called monkeypox (mpox), which sporadically infects humans in West and Central Africa. It first infected humans in 1970 and, along with the variola virus, belongs to the genus ... ...

    Abstract Monkeypox virus (MPXV) is responsible for causing a zoonotic disease called monkeypox (mpox), which sporadically infects humans in West and Central Africa. It first infected humans in 1970 and, along with the variola virus, belongs to the genus Orthopoxvirus in the poxvirus family. Since the World Health Organization declared the MPXV outbreak a "Public Health Emergency of International Concern" on July 23, 2022, the number of infected patients has increased dramatically. To control this epidemic and address this previously neglected disease, MPXV needs to be better understood and reevaluated. In this review, we cover recent research on MPXV, including its genomic and pathogenic characteristics, transmission, mutations and mechanisms, clinical characteristics, epidemiology, laboratory diagnosis, and treatment measures, as well as prevention of MPXV infection in light of the 2022 and 2023 global outbreaks. The 2022 MPXV outbreak has been primarily associated with close intimate contact, including sexual activity, with most cases diagnosed among men who have sex with men. The incubation period of MPXV infection usually lasts from 6 to 13 days, and symptoms include fever, muscle pains, headache, swollen lymph nodes, and a characteristic painful rash, including several stages, such as macules, papules, blisters, pustules, scabs, and scab shedding involving the genitals and anus. Polymerase chain reaction (PCR) is usually used to detect MPXV in skin lesion material. Treatment includes supportive care, antivirals, and intravenous vaccinia immune globulin. Smallpox vaccines have been designed with four givens emergency approval for use against MPXV infection.
    MeSH term(s) Male ; Animals ; Humans ; Mpox (monkeypox)/diagnosis ; Mpox (monkeypox)/drug therapy ; Mpox (monkeypox)/epidemiology ; Monkeypox virus/genetics ; Homosexuality, Male ; Sexual and Gender Minorities ; Zoonoses
    Language English
    Publishing date 2024-02-28
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1446080-4
    ISSN 1873-5967 ; 1386-6532
    ISSN (online) 1873-5967
    ISSN 1386-6532
    DOI 10.1016/j.jcv.2024.105662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Online: Effects of intestinal Desulfovibrio bacteria on host health and its potential regulatory strategies: A review.

    Zhou, Heyi / Huang, Dandan / Sun, Zetong / Chen, Xiaoyong

    Microbiological research

    2024  Volume 284, Page(s) 127725

    Abstract: Increasing studies have focused on the relationship between Desulfovibrio bacteria (DSV) and host health in recent years. However, little is known about the mechanisms by which DSV affects host health and the strategies to accurately regulate DSV numbers. ...

    Abstract Increasing studies have focused on the relationship between Desulfovibrio bacteria (DSV) and host health in recent years. However, little is known about the mechanisms by which DSV affects host health and the strategies to accurately regulate DSV numbers. This review mainly presents the relationship between DSV and host health, potential modulatory strategies, and the potential mechanisms affecting host health. Evidence suggests that DSV can both promote host health and induce the occurrence and development of disease, and these effects are closely related to its metabolites (e.g., H
    Language English
    Publishing date 2024-04-12
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1189614-0
    ISSN 1618-0623 ; 0944-5013
    ISSN (online) 1618-0623
    ISSN 0944-5013
    DOI 10.1016/j.micres.2024.127725
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  6. Article ; Online: Group-based trajectory modeling for fear of cancer recurrence in cancer survivors: a systematic review.

    Sun, Dandan / Fang, Huaying / Wang, Jin / Wu, Jinqiu

    Journal of cancer survivorship : research and practice

    2024  

    Abstract: Purpose: We aimed to systematically review studies that used a group-based trajectory modeling approach to explore the categories of fear of cancer recurrence (FCR) trajectories and their predictors in cancer survivors.: Methods: MEDLINE, EMBASE, ... ...

    Abstract Purpose: We aimed to systematically review studies that used a group-based trajectory modeling approach to explore the categories of fear of cancer recurrence (FCR) trajectories and their predictors in cancer survivors.
    Methods: MEDLINE, EMBASE, CINAHL, Scopus, and Web of Science were searched. Three authors independently reviewed the literature for predefined eligibility criteria. The Joanna Briggs Institute critical appraisal tools for Cohort Studies and the Guidelines for Reporting on Latent Trajectory Studies were used to assess the quality of included studies. A qualitative synthesis of the included studies was performed.
    Results: Ninety-eight studies were retrieved after removing duplicates, and 11 studies met the criteria for inclusion. There are four types of FCR trajectories: stable, decreasing, increasing, and stable-then-decreasing-then-increasing. The following factors were considered significant predictors of FCR trajectory category in at least one of the included studies: age, race, income, education, employment, cancer stage, physical symptoms, depression, anxiety, satisfaction with medical care, and selected cognitive and behavioral factors.
    Conclusions: There was considerable heterogeneity among the studies included in study design and FCR trajectory results. Factors that significantly predicted FCR trajectory categories mostly focused on psychological characteristics. The correlation of sociodemographic and disease-related predictors with FCR trajectory categories was not consistent among the included studies.
    Implications for cancer survivors: We suggest that future scholars should incorporate more psychological factors when identifying cancer survivors who persistently maintain a high level of FCR and developing FCR mitigation measures.
    Language English
    Publishing date 2024-04-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2388888-X
    ISSN 1932-2267 ; 1932-2259
    ISSN (online) 1932-2267
    ISSN 1932-2259
    DOI 10.1007/s11764-024-01582-7
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  7. Article ; Online: Significance of Microglial Energy Metabolism in Maintaining Brain Homeostasis.

    Bielanin, John P / Sun, Dandan

    Translational stroke research

    2022  Volume 14, Issue 4, Page(s) 435–437

    MeSH term(s) Microglia/metabolism ; Energy Metabolism ; Brain/metabolism ; Homeostasis
    Language English
    Publishing date 2022-07-26
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2541897-X
    ISSN 1868-601X ; 1868-4483
    ISSN (online) 1868-601X
    ISSN 1868-4483
    DOI 10.1007/s12975-022-01069-6
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  8. Article ; Online: Coexistence of neurofibromatosis type I and axial spondyloarthritis: a case report.

    Sun, Dandan / Jiang, Guan

    International journal of dermatology

    2022  Volume 62, Issue 3, Page(s) e174–e176

    MeSH term(s) Humans ; Neurofibromatosis 1 ; Spondylitis, Ankylosing ; Axial Spondyloarthritis
    Language English
    Publishing date 2022-11-03
    Publishing country England
    Document type Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.16486
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  9. Article ; Online: Relationship between vitamin D levels and pediatric celiac disease: a systematic review and meta-analysis.

    Sun, Yanhong / Zhou, Qingxue / Tian, Dandan / Zhou, Jianming / Dong, Shilei

    BMC pediatrics

    2024  Volume 24, Issue 1, Page(s) 185

    Abstract: Background: The relationship between Vitamin D levels and pediatric celiac disease (CD) remains controversial. In this study, we conducted a systematic review and meta-analysis to examine the relationship between Vitamin D and pediatric CD.: Methods: ...

    Abstract Background: The relationship between Vitamin D levels and pediatric celiac disease (CD) remains controversial. In this study, we conducted a systematic review and meta-analysis to examine the relationship between Vitamin D and pediatric CD.
    Methods: We screened relevant studies from PubMed, EMBASE, and Web of Science published in English from January 1, 2000, to August 1, 2023. The included studies were assessed according to the STROBE checklist. Heterogeneity was quantified by Cochran's Q test and the I
    Results: A total of 26 studies were included in the meta-analysis. Nineteen articles compared 25(OH)D3 levels between CD patients and control groups, average 25-hydroxyvitamin D
    Conclusions: Vitamin D levels in pediatric CD patients were lower than in healthy controls, and 25(OH)D
    MeSH term(s) Humans ; Child ; Prospective Studies ; Celiac Disease/complications ; Vitamin D ; Vitamins ; Calcitriol ; Vitamin D Deficiency/complications ; Vitamin D Deficiency/epidemiology
    Chemical Substances Vitamin D (1406-16-2) ; Vitamins ; Calcitriol (FXC9231JVH)
    Language English
    Publishing date 2024-03-16
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-024-04688-0
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  10. Article: Mushroom polysaccharides from

    Sun, Runbin / Jin, Dandan / Fei, Fei / Xu, Zhi / Cao, Bei / Li, Juan

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1172963

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-06-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1172963
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