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  1. Article ; Online: Psychosis in Patients in COVID-19-Related Quarantine: A Case Series.

    Finatti, Francesco / Pigato, Giorgio / Pavan, Chiara / Toffanin, Tommaso / Favaro, Angela

    The primary care companion for CNS disorders

    2020  Volume 22, Issue 3

    MeSH term(s) Adult ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/psychology ; Female ; Humans ; Male ; Pandemics ; Pneumonia, Viral/psychology ; Psychotic Disorders/diagnosis ; Psychotic Disorders/therapy ; Quarantine ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-14
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2675414-9
    ISSN 2155-7780 ; 2155-7772
    ISSN (online) 2155-7780
    ISSN 2155-7772
    DOI 10.4088/PCC.20l02640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of electroconvulsive therapy on cortical thickness in depression: a systematic review.

    Toffanin, Tommaso / Cattarinussi, Giulia / Ghiotto, Niccolò / Lussignoli, Marialaura / Pavan, Chiara / Pieri, Luca / Schiff, Sami / Finatti, Francesco / Romagnolo, Francesca / Folesani, Federica / Nanni, Maria Giulia / Caruso, Rosangela / Zerbinati, Luigi / Belvederi Murri, Martino / Ferrara, Maria / Pigato, Giorgio / Grassi, Luigi / Sambataro, Fabio

    Acta neuropsychiatrica

    2024  , Page(s) 1–15

    Abstract: Objective: Electroconvulsive therapy (ECT) is one of the most studied and validated available treatments for severe or treatment-resistant depression. However, little is known about the neural mechanisms underlying ECT. This systematic review aims to ... ...

    Abstract Objective: Electroconvulsive therapy (ECT) is one of the most studied and validated available treatments for severe or treatment-resistant depression. However, little is known about the neural mechanisms underlying ECT. This systematic review aims to critically review all structural magnetic resonance imaging studies investigating longitudinal cortical thickness (CT) changes after ECT in patients with unipolar or bipolar depression.
    Methods: We performed a search on PubMed, Medline, and Embase to identify all available studies published before April 20, 2023. A total of 10 studies were included.
    Results: The investigations showed widespread increases in CT after ECT in depressed patients, involving mainly the temporal, insular, and frontal regions. In five studies, CT increases in a non-overlapping set of brain areas correlated with the clinical efficacy of ECT. The small sample size, heterogeneity in terms of populations, comorbidities, and ECT protocols, and the lack of a control group in some investigations limit the generalisability of the results.
    Conclusions: Our findings support the idea that ECT can increase CT in patients with unipolar and bipolar depression. It remains unclear whether these changes are related to the clinical response. Future larger studies with longer follow-up are warranted to thoroughly address the potential role of CT as a biomarker of clinical response after ECT.
    Language English
    Publishing date 2024-02-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1154361-9
    ISSN 1601-5215 ; 0924-2708
    ISSN (online) 1601-5215
    ISSN 0924-2708
    DOI 10.1017/neu.2024.6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Psychosis in Patients in COVID-19-Related Quarantine: A Case Series

    Finatti, Francesco / Pigato, Giorgio / Pavan, Chiara / Toffanin, Tommaso / Favaro, Angela

    Prim. care companion CNS disord. (Online)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32408399
    Database COVID19

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  4. Article ; Online: THE NEUROPHENOMENOLOGY OF OUT-OF-BODY EXPERIENCES INDUCED BY HYPNOTIC SUGGESTIONS.

    Facco, Enrico / Casiglia, Edoardo / Al Khafaji, Benedikt Emanuel / Finatti, Francesco / Duma, Gian Marco / Mento, Giovanni / Pederzoli, Luciano / Tressoldi, Patrizio

    The International journal of clinical and experimental hypnosis

    2019  Volume 67, Issue 1, Page(s) 39–68

    Abstract: Inducing out-of-body experiences in hypnosis (H-OBEs) offers an almost unique opportunity to investigate them under controlled conditions. OBEs were induced as an imaginative task in a resting condition (I-OBE) or in hypnosis (H-OBE) in a group of 15 ... ...

    Abstract Inducing out-of-body experiences in hypnosis (H-OBEs) offers an almost unique opportunity to investigate them under controlled conditions. OBEs were induced as an imaginative task in a resting condition (I-OBE) or in hypnosis (H-OBE) in a group of 15 high hypnotizable subjects. A 32-channel EEG was recorded, and the spectral power and imaginary coherence of each frequency band and each couple of electrodes were calculated. At the end of each session, the Phenomenology of Consciousness Inventory (PCI) was administered to assess the phenomenological aspects of the subjects' experience. Significantly higher scores in the altered state, positive affect altered experience, and attention subdimensions of the PCI were reported in H-OBE than in I-OBE, which were associated with a significant decrease of power in beta and gamma band activity in right parieto-temporal derivations. These results suggest that the H-OBE may offer a useful experimental model of spontaneous OBEs.
    MeSH term(s) Adult ; Brain/physiology ; Electroencephalography ; Female ; Hallucinations/physiopathology ; Hallucinations/psychology ; Humans ; Male ; Middle Aged ; Suggestion ; Young Adult
    Language English
    Publishing date 2019-01-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 218267-1
    ISSN 1744-5183 ; 0020-7144
    ISSN (online) 1744-5183
    ISSN 0020-7144
    DOI 10.1080/00207144.2019.1553762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: MECHANISMS OF HYPNOTIC ANALGESIA EXPLAINED BY FUNCTIONAL MAGNETIC RESONANCE (fMRI).

    Casiglia, Edoardo / Finatti, Francesco / Tikhonoff, Valérie / Stabile, Maria R / Mitolo, Micaela / Albertini, Federica / Gasparotti, Federica / Facco, Enrico / Lapenta, Antonio M / Venneri, Annalena

    The International journal of clinical and experimental hypnosis

    2020  Volume 68, Issue 1, Page(s) 1–15

    Abstract: Hypnotic-focused analgesia (HFA) was produced in 20 highly hypnotizable subjects receiving nociceptive stimulations while undergoing functional magnetic resonance imaging (fMRI). The fMRI pattern in brain cortex activation while receiving a painful ... ...

    Abstract Hypnotic-focused analgesia (HFA) was produced in 20 highly hypnotizable subjects receiving nociceptive stimulations while undergoing functional magnetic resonance imaging (fMRI). The fMRI pattern in brain cortex activation while receiving a painful stimulus was recorded both during nonhypnosis and during HFA. The scanning protocol included the acquisition of a T1-weighted structural scan, 4 functional scans, a T2-weighted axial scan, and a fluid attenuated inversion recovery (FLAIR) scan. Total imaging time, including localization and structural image acquisitions, was approximately 60 minutes. Without HFA, the subjects reported subjective presence of pain, and the cortex primary sensory areas S1, S2, and S3 were activated. During HFA, the subjects reported complete absence of subjective pain and S1, S2, and S3 were deactivated. The findings suggest that HFA may prevent painful stimuli from reaching the sensory brain cortex, possibly through a gate-control mechanism.
    MeSH term(s) Adult ; Brain/physiology ; Female ; Functional Neuroimaging ; Humans ; Hypnosis, Anesthetic/methods ; Magnetic Resonance Imaging ; Male ; Pain/physiopathology ; Pain Management/methods
    Language English
    Publishing date 2020-01-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 218267-1
    ISSN 1744-5183 ; 0020-7144
    ISSN (online) 1744-5183
    ISSN 0020-7144
    DOI 10.1080/00207144.2020.1685331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Caffeine intake and abstract reasoning among 1374 unselected men and women from general population. Role of the -163C>A polymorphism of CYP1A2 gene.

    Casiglia, Edoardo / Tikhonoff, Valérie / Albertini, Federica / Favaro, Jacopo / Montagnana, Martina / Danese, Elisa / Finatti, Francesco / Benati, Marco / Mazza, Alberto / Dal Maso, Lucia / Spinella, Paolo / Palatini, Paolo

    Clinical nutrition ESPEN

    2017  Volume 20, Page(s) 52–59

    Abstract: Background and aims: The possible effect of caffeine as an enhancer of cognitive performance, particularly that on abstract reasoning, has never been studied in an epidemiological setting, especially in relation to -163C>A polymorphism of CYP1A2 gene, ... ...

    Abstract Background and aims: The possible effect of caffeine as an enhancer of cognitive performance, particularly that on abstract reasoning, has never been studied in an epidemiological setting, especially in relation to -163C>A polymorphism of CYP1A2 gene, largely controlling caffeine metabolism. Aim of this study was to ascertain whether in general population free chronic caffeine intake modifies abstract reasoning, and if this effect is influenced by the above mentioned genotype, by age, schooling, ethanol intake and smoking habits.
    Methods: We studied 1374 unselected men and women aged 51 ± 15 years (range 18-89) from a general population. Daily caffeine intake deriving from coffee, tea, chocolate or cola was calculated from an anamnestic questionnaire and from a 7-day dietary diary. Abstract reasoning was measured in the frame of a neuropsychological assessment as the ability to find a concept linking two words indicating objects or actions and explaining how they were connected.
    Results: In age-schooling-adjusted linear regression, the higher the caffeine intake, the better the abstraction score. Abstract reasoning depended on caffeine in the -163C>A CC homozygous only (so-called slow metabolizers), where it was higher in the 3rd tertile of caffeine intake. Age and ethanol reduced while smoking and schooling enhanced this association. The interaction term between caffeine and the -163C>A polymorphism was accepted in linear regressions. Caffeine consumption resulted innocuous for the A-carriers (so-called fast metabolizers).
    Conclusions: In general population, a positive association between caffeine intake and abstract reasoning exists in the CC homozygous of the -163C>A polymorphism of CYP1A2 gene.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Caffeine/pharmacology ; Central Nervous System Stimulants/pharmacology ; Cognition/drug effects ; Cytochrome P-450 CYP1A2/biosynthesis ; Cytochrome P-450 CYP1A2/genetics ; European Continental Ancestry Group/genetics ; Female ; Humans ; Italy ; Male ; Middle Aged ; Polymorphism, Genetic ; Population Surveillance ; Surveys and Questionnaires ; Young Adult
    Chemical Substances Central Nervous System Stimulants ; Caffeine (3G6A5W338E) ; Cytochrome P-450 CYP1A2 (EC 1.14.14.1)
    Language English
    Publishing date 2017-08
    Publishing country England
    Document type Journal Article
    ISSN 2405-4577
    ISSN (online) 2405-4577
    DOI 10.1016/j.clnesp.2017.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Caffeine intake and abstract reasoning among 1374 unselected men and women from general population. Role of the –163C>A polymorphism of CYP1A2 gene

    Casiglia, Edoardo / Tikhonoff, Valérie / Albertini, Federica / Favaro, Jacopo / Montagnana, Martina / Danese, Elisa / Finatti, Francesco / Benati, Marco / Mazza, Alberto / Dal Maso, Lucia / Spinella, Paolo / Palatini, Paolo

    European Society for Clinical Nutrition and Metabolism Clinical nutrition ESPEN. 2017 Aug., v. 20

    2017  

    Abstract: The possible effect of caffeine as an enhancer of cognitive performance, particularly that on abstract reasoning, has never been studied in an epidemiological setting, especially in relation to –163C>A polymorphism of CYP1A2 gene, largely controlling ... ...

    Abstract The possible effect of caffeine as an enhancer of cognitive performance, particularly that on abstract reasoning, has never been studied in an epidemiological setting, especially in relation to –163C>A polymorphism of CYP1A2 gene, largely controlling caffeine metabolism.Aim of this study was to ascertain whether in general population free chronic caffeine intake modifies abstract reasoning, and if this effect is influenced by the above mentioned genotype, by age, schooling, ethanol intake and smoking habits.We studied 1374 unselected men and women aged 51 ± 15 years (range 18–89) from a general population. Daily caffeine intake deriving from coffee, tea, chocolate or cola was calculated from an anamnestic questionnaire and from a 7-day dietary diary. Abstract reasoning was measured in the frame of a neuropsychological assessment as the ability to find a concept linking two words indicating objects or actions and explaining how they were connected.In age-schooling-adjusted linear regression, the higher the caffeine intake, the better the abstraction score. Abstract reasoning depended on caffeine in the –163C>A CC homozygous only (so-called slow metabolizers), where it was higher in the 3rd tertile of caffeine intake. Age and ethanol reduced while smoking and schooling enhanced this association. The interaction term between caffeine and the –163C>A polymorphism was accepted in linear regressions. Caffeine consumption resulted innocuous for the A-carriers (so-called fast metabolizers).In general population, a positive association between caffeine intake and abstract reasoning exists in the CC homozygous of the –163C>A polymorphism of CYP1A2 gene.
    Keywords caffeine ; chocolate ; cognition ; ethanol ; food records ; genes ; homozygosity ; men ; questionnaires ; regression analysis ; tea ; women
    Language English
    Dates of publication 2017-08
    Size p. 52-59.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 2405-4577
    DOI 10.1016/j.clnesp.2017.04.001
    Database NAL-Catalogue (AGRICOLA)

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