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  1. Article ; Online: Happy Hypoxemia in COVID-19-A Neural Hypothesis.

    U R, Anoop / Verma, Kavita

    ACS chemical neuroscience

    2020  Volume 11, Issue 13, Page(s) 1865–1867

    Abstract: Many COVID-19 patients are presenting with atypical clinical features. Happy hypoxemia with almost normal breathing, anosmia in the absence of rhinitis or nasal obstruction, and ageusia are some of the reported atypical clinical findings. Based on the ... ...

    Abstract Many COVID-19 patients are presenting with atypical clinical features. Happy hypoxemia with almost normal breathing, anosmia in the absence of rhinitis or nasal obstruction, and ageusia are some of the reported atypical clinical findings. Based on the clinical manifestations of the disease, we are proposing a new hypothesis that SARS-CoV-2 mediated inflammation of the nucleus tractus solitarius may be the reason for happy hypoxemia in COVID-19 patients.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/physiopathology ; Cranial Nerves/physiopathology ; Cranial Nerves/virology ; Humans ; Hypoxia/etiology ; Hypoxia/physiopathology ; Inflammation/etiology ; Inflammation/physiopathology ; Inflammation/virology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/physiopathology ; SARS-CoV-2 ; Solitary Nucleus/physiopathology ; Solitary Nucleus/virology
    Keywords covid19
    Language English
    Publishing date 2020-06-12
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1948-7193
    ISSN (online) 1948-7193
    DOI 10.1021/acschemneuro.0c00318
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pulmonary Edema in COVID19-A Neural Hypothesis.

    U R, Anoop / Verma, Kavita

    ACS chemical neuroscience

    2020  Volume 11, Issue 14, Page(s) 2048–2050

    Abstract: In COVID-19, lung manifestations present as a slowly evolving pneumonia with insidious early onset interstitial pulmonary edema that undergoes acute exacerbation in the late stages and microvascular thrombosis. Currently, these manifestations are ... ...

    Abstract In COVID-19, lung manifestations present as a slowly evolving pneumonia with insidious early onset interstitial pulmonary edema that undergoes acute exacerbation in the late stages and microvascular thrombosis. Currently, these manifestations are considered to be only consequences of pulmonary SARS-CoV-2 virus infection. We are proposing a new hypothesis that neurogenic insult may also play a major role in the pathogenesis of these manifestations. SARS-CoV-2 mediated inflammation of the nucleus tractus solitarius (NTS) may play a role in the acute exacerbation of pulmonary edema and microvascular clotting in COVID-19 patients.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Capillary Permeability/physiology ; Coronavirus Infections/immunology ; Coronavirus Infections/physiopathology ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/physiopathology ; Facial Nerve ; Glossopharyngeal Nerve ; Humans ; Hypotension/physiopathology ; Inflammation ; Lung/blood supply ; Lung/immunology ; Microvessels/immunology ; Microvessels/physiopathology ; Pandemics ; Parasympathetic Nervous System/physiopathology ; Pneumonia, Viral/immunology ; Pneumonia, Viral/physiopathology ; Pulmonary Edema/immunology ; Pulmonary Edema/physiopathology ; SARS-CoV-2 ; Solitary Nucleus/immunology ; Solitary Nucleus/physiopathology ; Thrombosis/physiopathology ; Vagus Nerve ; Vasoconstriction
    Keywords covid19
    Language English
    Publishing date 2020-07-02
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7193
    ISSN (online) 1948-7193
    DOI 10.1021/acschemneuro.0c00370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pulmonary Edema in COVID19—A Neural Hypothesis

    U.R., Anoop / Verma, Kavita

    ACS Chemical Neuroscience

    2020  Volume 11, Issue 14, Page(s) 2048–2050

    Keywords Cell Biology ; Biochemistry ; Physiology ; Cognitive Neuroscience ; General Medicine ; covid19
    Language English
    Publisher American Chemical Society (ACS)
    Publishing country us
    Document type Article ; Online
    ISSN 1948-7193
    DOI 10.1021/acschemneuro.0c00370
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Happy Hypoxemia in COVID-19—A Neural Hypothesis

    U.R., Anoop / Verma, Kavita

    ACS Chemical Neuroscience

    2020  Volume 11, Issue 13, Page(s) 1865–1867

    Keywords Cell Biology ; Biochemistry ; Physiology ; Cognitive Neuroscience ; General Medicine ; covid19
    Language English
    Publisher American Chemical Society (ACS)
    Publishing country us
    Document type Article ; Online
    ISSN 1948-7193
    DOI 10.1021/acschemneuro.0c00318
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: SARS-CoV-2

    Jayamuruga Pandian Arunachalam / Anoop U.R. / Kavita Verma / Rahini Rajendran / Subbulakshmi Chidambaram

    ACS Omega, Vol 6, Iss 10, Pp 7068-

    The Road Less TraveledFrom the Respiratory Mucosa to the Brain

    2021  Volume 7072

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Pulmonary Edema in COVID19-A Neural Hypothesis

    U R, Anoop / Verma, Kavita

    ACS Chem Neurosci

    Abstract: In COVID-19, lung manifestations present as a slowly evolving pneumonia with insidious early onset interstitial pulmonary edema that undergoes acute exacerbation in the late stages and microvascular thrombosis. Currently, these manifestations are ... ...

    Abstract In COVID-19, lung manifestations present as a slowly evolving pneumonia with insidious early onset interstitial pulmonary edema that undergoes acute exacerbation in the late stages and microvascular thrombosis. Currently, these manifestations are considered to be only consequences of pulmonary SARS-CoV-2 virus infection. We are proposing a new hypothesis that neurogenic insult may also play a major role in the pathogenesis of these manifestations. SARS-CoV-2 mediated inflammation of the nucleus tractus solitarius (NTS) may play a role in the acute exacerbation of pulmonary edema and microvascular clotting in COVID-19 patients.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #627315
    Database COVID19

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  7. Article: Happy Hypoxemia in COVID-19-A Neural Hypothesis

    U R, Anoop / Verma, Kavita

    ACS chem. neurosci

    Abstract: Many COVID-19 patients are presenting with atypical clinical features. Happy hypoxemia with almost normal breathing, anosmia in the absence of rhinitis or nasal obstruction, and ageusia are some of the reported atypical clinical findings. Based on the ... ...

    Abstract Many COVID-19 patients are presenting with atypical clinical features. Happy hypoxemia with almost normal breathing, anosmia in the absence of rhinitis or nasal obstruction, and ageusia are some of the reported atypical clinical findings. Based on the clinical manifestations of the disease, we are proposing a new hypothesis that SARS-CoV-2 mediated inflammation of the nucleus tractus solitarius may be the reason for happy hypoxemia in COVID-19 patients.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32530597
    Database COVID19

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  8. Article ; Online: SARS-CoV-2: The Road Less Traveled-From the Respiratory Mucosa to the Brain.

    Arunachalam, Jayamuruga Pandian / U R, Anoop / Verma, Kavita / Rajendran, Rahini / Chidambaram, Subbulakshmi

    ACS omega

    2021  Volume 6, Issue 10, Page(s) 7068–7072

    Abstract: Neurological manifestations have been reported in COVID-19; however, the route used by SARS-CoV-2 to enter the brain is still under debate. Recent studies have focused on the olfactory route. SARS-CoV-2 viral proteins were also detected in the ... ...

    Abstract Neurological manifestations have been reported in COVID-19; however, the route used by SARS-CoV-2 to enter the brain is still under debate. Recent studies have focused on the olfactory route. SARS-CoV-2 viral proteins were also detected in the glossopharyngeal and vagal nerves originating from the lower brainstem and in isolated cells of the brainstem. Our proof of concept
    Language English
    Publishing date 2021-03-03
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.1c00030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Efficacious slosh suppression technique in road tankers to enhance the effectiveness of drinking water distribution.

    G, Unnikrishnan / R, Anoop F / Suryan, Abhilash / Sanker P S, Pramoj

    Chemosphere

    2022  Volume 310, Page(s) 136752

    Abstract: During summer months, many parts of the world experience the water crisis and water tankers transport fresh drinking water from rivers and other reservoirs and distribute to communities often located at far off places. Effectiveness of this distribution ... ...

    Abstract During summer months, many parts of the world experience the water crisis and water tankers transport fresh drinking water from rivers and other reservoirs and distribute to communities often located at far off places. Effectiveness of this distribution is adversely affected by the instability of tankers due to the phenomenon called liquid sloshing, the oscillation of free liquid surface subjected to external excitation. The liquid within the tank moves along the side walls back and forth creating an oscillation which becomes dangerously worse at certain situations. Sloshing makes the tanker unstable when the operating frequency and the tanker frequency coincides which may even cause the tanker to roll over. Hence, quite often, the tankers have to be operated on roads only at its maximum capacity and the water left in the tank may have to be spilled and wasted if the storage facility at the destination is less than the tanker capacity. In this work we are proposing an optimum design of water tankers to minimize the effect of sloshing and thereby enabling trouble-free operation of the tankers even in partially filled conditions. Sloshing parameters such as slosh height and dynamic wall pressures are experimentally and numerically analyzed for various tank geometries with and without baffles. A numerical model for analyzing slosh parameters is also developed and validated using experimental results. Based on the study an optimized tanker configuration is proposed.
    MeSH term(s) Drinking Water ; Seasons
    Chemical Substances Drinking Water
    Language English
    Publishing date 2022-10-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2022.136752
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The ECG made easy for the dental practitioner.

    Anoop, U R / Verma, Kavita

    Indian journal of dental research : official publication of Indian Society for Dental Research

    2014  Volume 25, Issue 3, Page(s) 386–389

    Abstract: ECG is not taught to dental students formally in the dental curriculum. The general assumption is that dental surgeons do not handle any ECG related cases in clinical practice. But with an increase in medically compromised patients, the need for an ... ...

    Abstract ECG is not taught to dental students formally in the dental curriculum. The general assumption is that dental surgeons do not handle any ECG related cases in clinical practice. But with an increase in medically compromised patients, the need for an interdisciplinary approach among dental and medical practitioners in the treatment of critically ill patients is becoming more relevant. Hence, we have to be aware of the basics of common medical investigations to be competent to assess and comprehend the medical conditions. So, this paper focuses on orienting the beginner to the basic concepts of ECG from the clinical perspective. The paper also discusses the ECG changes of myocardial infarction to familiarize the dental surgeon to read the ECG.
    MeSH term(s) Dentists ; Electrocardiography/instrumentation ; Electrocardiography/methods ; Humans
    Language English
    Publishing date 2014-05
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 1354886-4
    ISSN 1998-3603 ; 0970-9290
    ISSN (online) 1998-3603
    ISSN 0970-9290
    DOI 10.4103/0970-9290.138349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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