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  1. Article: Hypermetabolic Pulmonary and Mediastinal Lesions With Elevated Cancer Antigen (CA) 15-3 and CA 27-29 in a Patient With a History of Ovarian and Breast Cancer.

    Venkatram, Sindhaghatta / Duran, Maria / Fortuzi, Ked / Baqui, Aam / Luong, Thanh-Ha / Diaz-Fuentes, Gilda

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55712

    Abstract: Breast cancer affects around 13% of women. Breast cancer gene 1 ( ...

    Abstract Breast cancer affects around 13% of women. Breast cancer gene 1 (
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Unusual Aspergillus Pleural Effusion in a Patient With Immunodeficiency.

    Fortuzi, Ked / Khanal, Sneha / Schmidt, Patrik / Bhatt, Tanushree / Khaja, Misbahuddin

    Cureus

    2023  Volume 15, Issue 10, Page(s) e46308

    Abstract: Pleural aspergillosis is a rare form of invasive bronchopulmonary aspergillosis that is most often seen in immunocompromised hosts. It appears because of the coagulative necrosis of lung tissue induced by ... ...

    Abstract Pleural aspergillosis is a rare form of invasive bronchopulmonary aspergillosis that is most often seen in immunocompromised hosts. It appears because of the coagulative necrosis of lung tissue induced by the
    Language English
    Publishing date 2023-10-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.46308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Glass in the Airways: A Bronchoscopic Challenge.

    Doppalapudi, Sai / Fortuzi, Ked / Qasim, Abeer / Yordanka, Diaz Saez / Khaja, Misbahuddin

    Cureus

    2024  Volume 16, Issue 1, Page(s) e53344

    Abstract: Foreign body aspiration (FBA) in adults is indeed a significant medical concern, albeit less common than in children. The increase in incidence with advancing age can be attributed to factors such as a decline in mental status and impairment of the ... ...

    Abstract Foreign body aspiration (FBA) in adults is indeed a significant medical concern, albeit less common than in children. The increase in incidence with advancing age can be attributed to factors such as a decline in mental status and impairment of the swallowing reflex, which is more prevalent in the elderly population. The symptoms of FBA are highly variable, ranging from severe, acute asphyxiation, which may or may not involve complete airway obstruction, to more subtle signs like coughing, shortness of breath (dyspnea), choking, or fever. These varied presentations, coupled with the fact that many other medical conditions can mimic the respiratory symptoms seen in FBA, make diagnosis challenging. A high index of suspicion is often required, especially in cases where the patient's history does not clearly point toward aspiration. Immediate management focuses on supporting the airway, which is crucial given the potential for severe obstruction. Radiographic imaging plays a key role in localizing the foreign body, which is vital for planning its removal. Bronchoscopy, particularly flexible bronchoscopy, is the cornerstone of both diagnosis and treatment. This technique allows for direct visualization of the airways, localization of the foreign body, and its subsequent removal. This is crucial to avoid long-term complications, which can arise if the foreign body is not promptly and effectively removed. In this case report, we present a 64-year-old female patient who was found to have a foreign object positioned in the right lower lobe of the lungs that was removed via flexible bronchoscopy.
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.53344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Metastatic Prostate Cancer With Reticular Micronodular Opacities of Lung: A Case Report.

    Bojja, Srikaran / Javed, Nismat / Aziz, Muhammad Ali / Fortuzi, Ked / Khaja, Misbahuddin

    Cureus

    2023  Volume 15, Issue 7, Page(s) e42698

    Abstract: Prostate cancer, a common malignancy in males, can metastasize to various sites such as the bone, brain, liver, and less commonly, the lung. Detecting pulmonary metastases presents both diagnostic and therapeutic difficulties. Identifying patients with ... ...

    Abstract Prostate cancer, a common malignancy in males, can metastasize to various sites such as the bone, brain, liver, and less commonly, the lung. Detecting pulmonary metastases presents both diagnostic and therapeutic difficulties. Identifying patients with this condition is crucial for gaining a deeper comprehension of the disease's pathogenesis. In this report, we describe the case of a 64-year-old African American male who exhibited elevated prostate antigen levels and was found to have unique reticular Micronodular opacities in the lungs caused by prostate cancer.
    Language English
    Publishing date 2023-07-30
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.42698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Cryptococcosis and Cryptococcal Meningitis: A Narrative Review and the Up-to-Date Management Approach.

    Qureshi, Zaheer A / Ghazanfar, Haider / Altaf, Faryal / Ghazanfar, Ali / Hasan, Khushbu Z / Kandhi, Sameer / Fortuzi, Ked / Dileep, Arundhati / Shrivastava, Shitij

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55498

    Abstract: Cryptococcosis is a fungal infectious disease that enormously impacts human health worldwide. Cryptococcal meningitis is the most severe disease caused by the fungus Cryptococcus, and can lead to death, if left untreated. Many patients develop resistance ...

    Abstract Cryptococcosis is a fungal infectious disease that enormously impacts human health worldwide. Cryptococcal meningitis is the most severe disease caused by the fungus Cryptococcus, and can lead to death, if left untreated. Many patients develop resistance and progress to death even after treatment. It requires a prolonged treatment course in people with AIDS. This narrative review provides an evidence-based summary of the current treatment modalities and future trial options, including newer ones, namely, 18B7, T-2307, VT-1598, AR12, manogepix, and miltefosine. This review also evaluated the management and empiric treatment of cryptococcus meningitis. The disease can easily evade diagnosis with subacute presentation. Despite the severity of the disease, treatment options for cryptococcosis remain limited, and more research is needed.
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Comparison of patients admitted to an inner-city intensive care unit across 3 COVID-19 waves.

    Venkatram, Sindhaghatta / Dileep, Arundhati / Fortuzi, Ked / Allena, Nishant / Diaz-Fuentes, Gilda

    Medicine

    2023  Volume 102, Issue 8, Page(s) e33069

    Abstract: To expand our limited knowledge of COVID-19-related outcomes in patients admitted to inner-city intensive care unit (ICU across multiple infection waves. This retrospective study compared patients admitted to the ICU in Bronx, NY, during 3 COVID-19 waves ...

    Abstract To expand our limited knowledge of COVID-19-related outcomes in patients admitted to inner-city intensive care unit (ICU across multiple infection waves. This retrospective study compared patients admitted to the ICU in Bronx, NY, during 3 COVID-19 waves (March 2020 to February 2022). Outcomes included in hospital mortality, length of stay (LOS), use of mechanical ventilation, and discharge disposition. The study included 716 patients (343, 276, and 97 in the first, second, and third COVID-19 waves, respectively). The number of days on mechanical ventilation and LOS were lower in the first wave. Of the 345 discharged patients, 37% went home directly, whereas 11% were discharged to a skill nursing facility. More patients went home during the second and third waves. Mortality decreased from the first to the third waves (57%-37%; P < .001). Predictors of mortality included age, male gender, COPD, shock, acute kidney injury (AKI), dialysis requirement, and mechanical ventilation. The decreased mortality and better discharge disposition of these inner-city patients during the second and third waves is encouraging, as this population historically had a high COVID-19-related mortality risk.
    MeSH term(s) Humans ; Male ; COVID-19 ; Retrospective Studies ; Renal Dialysis ; Hospitalization ; Intensive Care Units ; Hospital Mortality
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000033069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A Rare Case of Concomitant Septic Arthritis, Osteomyelitis, and Pyomyositis Caused by Salmonella.

    Ghazanfar, Haider / Nawaz, Iqra / Fortuzi, Ked / Tieng, Arlene / Franchin, Giovanni

    Cureus

    2021  Volume 13, Issue 12, Page(s) e20365

    Abstract: A common causative organism in osteomyelitis in sickle cell disease ... ...

    Abstract A common causative organism in osteomyelitis in sickle cell disease is
    Language English
    Publishing date 2021-12-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.20365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Apixaban Causing Hepatic Cystic Bleeding: A Rare but a Life-Threatening Complication.

    Shehi, Elona / Fortuzi, Ked / Ghazanfar, Haider / Mehershahi, Shehriyar / Balar, Bhavna

    Case reports in gastroenterology

    2021  Volume 15, Issue 3, Page(s) 904–909

    Abstract: Cystic lesions of the liver are a heterogeneous group of disorders with varied etiology, prevalence, and clinical manifestations. Fibropolycystic liver disease encompasses a spectrum of related liver and biliary tract lesions caused by abnormal ... ...

    Abstract Cystic lesions of the liver are a heterogeneous group of disorders with varied etiology, prevalence, and clinical manifestations. Fibropolycystic liver disease encompasses a spectrum of related liver and biliary tract lesions caused by abnormal embryologic development of the ductal plates. These disorders include congenital hepatic fibrosis, biliary hamartomas, polycystic liver disease (PCLD), choledochal cysts, and Carolis disease. PCLD is arbitrarily defined as a liver that contains >20 cysts. Most liver cysts are incidentally found on imaging studies, and the majority of the patients with liver cysts are asymptomatic. Rarely, complications such as compression, infection, and bleeding within the cyst can occur. Under the effect of the increased pressure, the epithelial lining of the cyst undergoes necrosis and sloughing, causing injury of the fragile blood vessels, leading to intracystic bleeding. The bleeding within or from the cyst can be precipitated by anticoagulation. We present a patient with PCLD who developed intracystic bleeding after he was started on apixaban for the prevention of thromboembolism.
    Language English
    Publishing date 2021-10-11
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000519276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: An Atypical Presentation of Chronic Inflammatory Myelin Degeneration in Neuromyelitis Optica (NMO).

    Allu, Sai Vishnu Vardhan / Parikh, Harsh R / Schmidt, Patrik / Alonso, Gabriel / Khanal, Sneha / Fortuzi, Ked / Khaja, Misbahuddin

    Cureus

    2023  Volume 15, Issue 7, Page(s) e41803

    Abstract: Neuromyelitis optica (NMO) is an autoimmune disorder characterized by aquaporin-4 (AQP4) IgG autoantibodies. These autoantibodies induce chronic neuroinflammatory damage to the spinal cord and optic nerve. NMO clinically manifests as relapsing and ... ...

    Abstract Neuromyelitis optica (NMO) is an autoimmune disorder characterized by aquaporin-4 (AQP4) IgG autoantibodies. These autoantibodies induce chronic neuroinflammatory damage to the spinal cord and optic nerve. NMO clinically manifests as relapsing and overlapping neurodegenerative episodes of optic neuritis (ON) and transverse myelitis (TM). Contrasting from other autoimmune neurodegenerative disorders, NMO has a poor prognostic profile often involving permanent neurological disability. We present a case of a 65-year-old male who presented with a progressive weakening in his left upper and lower extremities with reduced sensation and was found to have an acute flare of NMO. We explore the broad symptomatology involved in the disorder along with relevant crucial imaging findings pointing toward the diagnosis of NMO. Finally, we discuss treatment modalities in the context of our patient's clinical course and prognostic factors. Early intervention and suppression of relapse in this neuroinflammatory neurodegenerative disorder can help decrease the duration of acute flares and improve long-term outcomes for patients affected by NMO.
    Language English
    Publishing date 2023-07-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.41803
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: May-Thurner Syndrome: A Rare Case of Unilateral Deep Vein Thrombosis in an Elderly Woman.

    Siddiqa, Ayesha / Haider, Asim / Fortuzi, Ked / Adrish, Muhammad / Ishak, Charbel

    The American journal of case reports

    2021  Volume 22, Page(s) e929897

    Abstract: BACKGROUND Deep vein thrombosis (DVT) is a critical disorder with a high incidence and a high disease burden. Multiple acquired and genetic factors leading to hypercoagulation, venous injury, and venous stasis account for its basic pathophysiology. One ... ...

    Abstract BACKGROUND Deep vein thrombosis (DVT) is a critical disorder with a high incidence and a high disease burden. Multiple acquired and genetic factors leading to hypercoagulation, venous injury, and venous stasis account for its basic pathophysiology. One of the rarely considered underlying etiologies of DVT is May-Thurner Syndrome (MTS), also known as iliac vein compression syndrome. MTS is an anatomical variant in which the left common iliac vein is extrinsically compressed by the right common iliac artery against the lumbar spine, leading to the development of iliofemoral DVT. CASE REPORT We present the case of a 78-year-old woman who presented with chronic unilateral lower-extremity swelling and pain. Ultrasound was consistent with extensive DVT extending from the left common femoral vein to left popliteal vein. Further workup revealed left common iliac venous outflow obstruction due to the extrinsic compression by the overlying atherosclerotic calcified right common iliac artery crossing against the lumbosacral region. CONCLUSIONS MTS usually presents in the second to fourth decades of life, making it challenging to consider it as a differential diagnosis in older patients. The conventional treatment of DVT with anticoagulation alone is insufficient to address thrombotic MTS and can lead to recurrent DVT, post-thrombotic syndrome, and life-threatening complications. Our patient presented in the seventh decade of life, warranting a high index of clinical suspicion of MTS in patients presenting with unilateral leg DVT, regardless of patient age, for timely diagnosis and appropriate therapeutic management.
    MeSH term(s) Aged ; Female ; Femoral Vein ; Humans ; Iliac Artery ; Iliac Vein/diagnostic imaging ; May-Thurner Syndrome/complications ; May-Thurner Syndrome/diagnostic imaging ; Venous Thrombosis/etiology
    Language English
    Publishing date 2021-08-30
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.929897
    Database MEDical Literature Analysis and Retrieval System OnLINE

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