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  1. Article: The Co-Occurrence of Sexsomnia, Sleep Bruxism and Other Sleep Disorders.

    Martynowicz, Helena / Smardz, Joanna / Wieczorek, Tomasz / Mazur, Grzegorz / Poreba, Rafal / Skomro, Robert / Zietek, Marek / Wojakowska, Anna / Michalek, Monika / Wieckiewicz, Mieszko

    Journal of clinical medicine

    2018  Volume 7, Issue 9

    Abstract: Background: Sleep sex also known as sexsomnia or somnambulistic sexual behavior is proposed to be classified as NREM (non-rapid eye movement) parasomnia (as a clinical subtype of disorders of arousal from NREM sleep-primarily confusional arousals or ... ...

    Abstract Background: Sleep sex also known as sexsomnia or somnambulistic sexual behavior is proposed to be classified as NREM (non-rapid eye movement) parasomnia (as a clinical subtype of disorders of arousal from NREM sleep-primarily confusional arousals or less commonly sleepwalking), but it has also been described in relation to REM (rapid eye movement) parasomnias.
    Methods: The authors searched the PubMed database to identify relevant publications and present the co-occurrence of sexsomnia and other sleep disorders as a non-systematic review with case series.
    Results: In the available literature the comorbidity of sexsomnia and other sleep disorders were reported mainly in case reports and less in case series. Sexsomnia was reported both with one and with multiple sleep-related disorders, with NREM parasomnias and obstructive sleep apnea (OSA) being the most commonly reported. Furthermore, the authors enrich the article with new findings concerning two novel cases of sleep bruxism triggering recurrent sexsomnia episodes.
    Conclusions: Sexsomnia has still not been reported in the literature as often as other parasomnias. The coexistence of sexsomnia and other sleep-related disorders should be more thoroughly examined. This could help both in sexsomnia as well as other sleep-related disorders management.
    Language English
    Publishing date 2018-08-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm7090233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Pulmonary blastomycosis: an appraisal of diagnostic techniques.

    Martynowicz, Marek A / Prakash, Udaya B S

    Chest

    2002  Volume 121, Issue 3, Page(s) 768–773

    Abstract: Objectives: Pulmonary blastomycosis often mimics bacterial pneumonia or bronchogenic carcinoma, which may result in delayed therapy or the performance of unnecessary diagnostic procedures. We have reviewed the utilization of diagnostic techniques in the ...

    Abstract Objectives: Pulmonary blastomycosis often mimics bacterial pneumonia or bronchogenic carcinoma, which may result in delayed therapy or the performance of unnecessary diagnostic procedures. We have reviewed the utilization of diagnostic techniques in the workup of patients with pulmonary blastomycosis, defined their diagnostic yields, and proposed an optimal diagnostic approach for the patient in whom pulmonary blastomycosis is considered.
    Design: Retrospective chart review of all patients with the diagnosis of blastomycosis at a major academic medical center.
    Results: Of the 119 patients with blastomycosis, 56 (47%) had pulmonary involvement. A total of 92 specimens were obtained by noninvasive means (sputa, 72 specimens; tracheal secretions, 5 specimens; and gastric washings, 15 specimens) in 35 patients. KOH smears were prepared from 22 of those specimens (24%). The diagnostic yield from these culture specimens obtained by noninvasive means was 86% per patient, and 75% per single sample. The diagnostic yields from KOH smears were 46% and 36%, respectively. Flexible bronchoscopy was performed in 24 patients and yielded a diagnosis in 22 (92%). Cultures of bronchial secretions (19 patients) and BAL fluid (6 patients) were positive in 100% and 67% of patients, respectively. The corresponding yields of KOH preparations were 17% (1 of 6 preparations) and 50% (3 of 6 preparations), respectively. Pathology specimens including those from bronchoscopic lung biopsies (nine patients), bronchial brushings (two patients), and bronchoscopic needle aspiration (one patient) were positive in 22%, 50%, and 0% of cases, respectively. Cytology was usually performed to exclude malignancy and was positive for Blastomyces dermatitidis in five patients (sputum, three patients; bronchial washings, two patients). Thoracotomy was performed in 11 cases, and in all patients the procedure yielded a diagnosis. Serology results were available in 25 patients. Immunodiffusion was positive in 10 patients (40%), and complement fixation in 4 patients (16%).
    Conclusions: In patients with pulmonary blastomycosis, the positive yield from respiratory specimen cultures is high, but the confirmation of a diagnosis may take up to 5 weeks. Wet smears and cytology examinations of respiratory specimens provide quicker diagnoses but are underutilized. Their routine use is recommended in endemic areas. Commonly used serologic assays are insensitive and are not useful for diagnostic screening.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Blastomycosis/diagnosis ; Bronchoscopy ; Child ; Female ; Humans ; Lung Diseases, Fungal/diagnosis ; Male ; Middle Aged ; Retrospective Studies ; Specimen Handling ; Sputum/microbiology
    Language English
    Publishing date 2002-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1378/chest.121.3.768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui III Zs.45: Show issues Location:
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  3. Article ; Online: The Co-Occurrence of Sexsomnia, Sleep Bruxism and Other Sleep Disorders

    Helena Martynowicz / Joanna Smardz / Tomasz Wieczorek / Grzegorz Mazur / Rafal Poreba / Robert Skomro / Marek Zietek / Anna Wojakowska / Monika Michalek / Mieszko Wieckiewicz

    Journal of Clinical Medicine, Vol 7, Iss 9, p

    2018  Volume 233

    Abstract: Background: Sleep sex also known as sexsomnia or somnambulistic sexual behavior is proposed to be classified as NREM (non-rapid eye movement) parasomnia (as a clinical subtype of disorders of arousal from NREM sleep—primarily confusional arousals or less ...

    Abstract Background: Sleep sex also known as sexsomnia or somnambulistic sexual behavior is proposed to be classified as NREM (non-rapid eye movement) parasomnia (as a clinical subtype of disorders of arousal from NREM sleep—primarily confusional arousals or less commonly sleepwalking), but it has also been described in relation to REM (rapid eye movement) parasomnias. Methods: The authors searched the PubMed database to identify relevant publications and present the co-occurrence of sexsomnia and other sleep disorders as a non-systematic review with case series. Results: In the available literature the comorbidity of sexsomnia and other sleep disorders were reported mainly in case reports and less in case series. Sexsomnia was reported both with one and with multiple sleep-related disorders, with NREM parasomnias and obstructive sleep apnea (OSA) being the most commonly reported. Furthermore, the authors enrich the article with new findings concerning two novel cases of sleep bruxism triggering recurrent sexsomnia episodes. Conclusions: Sexsomnia has still not been reported in the literature as often as other parasomnias. The coexistence of sexsomnia and other sleep-related disorders should be more thoroughly examined. This could help both in sexsomnia as well as other sleep-related disorders management.
    Keywords sexsomnia ; sleep sex ; sleep bruxism ; sleepwalking ; sleep talking ; obstructive sleep apnea ; video-polisomnography ; Medicine ; R
    Subject code 150
    Language English
    Publishing date 2018-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article: Czynniki ryzyka zwiqzane z praca zawodowa a rak sutka u mezczyzn.

    Martynowicz, Helena / Medraś, Marek / Andrzejak, Ryszard

    Medycyna pracy

    2005  Volume 56, Issue 5, Page(s) 405–410

    Abstract: Male breast cancer is rare compared to its female counterpart and makes less than 1% of all breast cancer. Its etiology is less known than that of female breast cancer. Numerous experimental and clinical studies indicate the possibility of an increased ... ...

    Title translation Occupational risk factors and male breast cancer.
    Abstract Male breast cancer is rare compared to its female counterpart and makes less than 1% of all breast cancer. Its etiology is less known than that of female breast cancer. Numerous experimental and clinical studies indicate the possibility of an increased risk of male breast cancer in workers occupationally exposed to electromagnetic field, light at night, and high temperature. There are also studies, which reveal the increased risk of this disease induced by occupational exposure to pesticides, aromatic hydrocarbons and ionizing radiation. However, irrefutable epidemiologic data from prospective clinical trials have not yet been obtained.
    MeSH term(s) Breast Neoplasms, Male/diagnosis ; Breast Neoplasms, Male/epidemiology ; Breast Neoplasms, Male/prevention & control ; Carcinogens, Environmental/toxicity ; Electromagnetic Fields ; Hot Temperature ; Humans ; Male ; Occupational Diseases/chemically induced ; Occupational Diseases/diagnosis ; Occupational Diseases/epidemiology ; Occupational Diseases/prevention & control ; Occupational Exposure/analysis ; Occupational Exposure/statistics & numerical data ; Pesticides/toxicity ; Poland
    Chemical Substances Carcinogens, Environmental ; Pesticides
    Language Polish
    Publishing date 2005
    Publishing country Poland
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 128739-4
    ISSN 0465-5893
    ISSN 0465-5893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1976: Show issues Location:
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  5. Article: Wpływ ołowiu na funkcje gonad meskich.

    Martynowicz, Helena / Andrzejak, Ryszard / Medraś, Marek

    Medycyna pracy

    2005  Volume 56, Issue 6, Page(s) 495–500

    Abstract: The deterioration of male fertility, found in numerous epidemiological studies of past decades, can be connected to growing exposure to environmental toxins. Heavy metals, especially lead is widely spread and extremely toxic. The mechanism by which lead ... ...

    Title translation The influence of lead on testis function.
    Abstract The deterioration of male fertility, found in numerous epidemiological studies of past decades, can be connected to growing exposure to environmental toxins. Heavy metals, especially lead is widely spread and extremely toxic. The mechanism by which lead exerts toxic effects on testis is quite complex. It involves spermatogenesis, steroidogenesis, and red-ox system. The chronic lead exposure can induce functional disorder (decrease of testosterone synthesis) or morphological disorder (decrease of testicular weight and seminal vesicle, peritubular fibrosis, seminiferous tubular diameter decrease and decrease in germ cell population related to an apoptotic process). Currently existing environmental and occupational exposure to lead and increasing combined exposure to environmental toxins results in constantly increasing number of diagnosed fertility impairments.
    MeSH term(s) Causality ; Comorbidity ; Environmental Exposure/adverse effects ; Environmental Exposure/statistics & numerical data ; Hazardous Substances/adverse effects ; Humans ; Infertility, Male/chemically induced ; Infertility, Male/epidemiology ; Infertility, Male/prevention & control ; Lead/toxicity ; Lead Poisoning/epidemiology ; Male ; Occupational Exposure/adverse effects ; Occupational Exposure/statistics & numerical data ; Spermatogenesis/drug effects ; Testis/drug effects
    Chemical Substances Hazardous Substances ; Lead (2P299V784P)
    Language Polish
    Publishing date 2005
    Publishing country Poland
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 128739-4
    ISSN 0465-5893
    ISSN 0465-5893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  6. Article: Opposing effects of emphysema, hay fever, and select genetic variants on lung cancer risk.

    Schabath, Matthew B / Delclos, George L / Martynowicz, Marek M / Greisinger, Anthony J / Lu, Charles / Wu, Xifeng / Spitz, Margaret R

    American journal of epidemiology

    2005  Volume 161, Issue 5, Page(s) 412–422

    Abstract: The authors compared histories of nonmalignant respiratory diseases (asthma, bronchitis, emphysema, hay fever, and pneumonia) in 1,553 lung cancer patients and 1,375 healthy controls enrolled in a Texas case-control study from 1995 to 2003. They ... ...

    Abstract The authors compared histories of nonmalignant respiratory diseases (asthma, bronchitis, emphysema, hay fever, and pneumonia) in 1,553 lung cancer patients and 1,375 healthy controls enrolled in a Texas case-control study from 1995 to 2003. They incorporated data on two biologically relevant polymorphic genes, matrix metalloproteinase-1 and myeloperoxidase. Emphysema was associated with a statistically significant increased lung cancer risk (odds ratio (OR) = 2.87, 95% confidence interval (CI): 2.20, 3.76), while hay fever had a significant protective effect (OR = 0.58, 95% CI: 0.48, 0.70). Odds ratios were consistent after exclusion of respiratory disease diagnoses made up to 10 years before interview. There was little association between other respiratory diseases and lung cancer risk. Among carriers of "protective" genotypes, emphysema was associated with a 1.7-fold increased risk (95% CI: 0.84, 3.50), as compared with the substantially higher risk for persons possessing one (OR = 4.98, 95% CI: 2.94, 8.44) or two (OR = 4.23, 95% CI: 1.84, 9.73) "adverse" genotypes. For hay fever, significantly decreased risks were evident with one (OR = 0.32, 95% CI: 0.21, 0.50) or two (OR = 0.35, 95% CI: 0.19, 0.66) protective genotypes as compared with none (OR = 0.69, 95% CI: 0.30, 1.59). The biologic role of respiratory disease in lung cancer is unclear. Further study may yield new insights for identification of susceptible subgroups.
    MeSH term(s) Asthma/genetics ; Bronchitis/epidemiology ; Bronchitis/genetics ; Case-Control Studies ; Chi-Square Distribution ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Logistic Models ; Lung Neoplasms/enzymology ; Lung Neoplasms/epidemiology ; Lung Neoplasms/genetics ; Male ; Matrix Metalloproteinase 1/genetics ; Middle Aged ; Peroxidase/genetics ; Pneumonia/epidemiology ; Pneumonia/genetics ; Polymorphism, Genetic ; Pulmonary Emphysema/epidemiology ; Pulmonary Emphysema/genetics ; Rhinitis, Allergic, Seasonal/epidemiology ; Rhinitis, Allergic, Seasonal/genetics ; Risk Factors ; Texas/epidemiology
    Chemical Substances Peroxidase (EC 1.11.1.7) ; Matrix Metalloproteinase 1 (EC 3.4.24.7)
    Language English
    Publishing date 2005-03-01
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2937-3
    ISSN 1476-6256 ; 0002-9262
    ISSN (online) 1476-6256
    ISSN 0002-9262
    DOI 10.1093/aje/kwi063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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