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  1. Article ; Online: Pulmonary embolism in a returning traveller with COVID-19 pneumonia.

    Foch, Emilie / Allou, Nathalie / Vitry, Thierry / Masse, Laurie / Allyn, Jérôme / Andre, Michel / Allou, Nicolas

    Journal of travel medicine

    2020  Volume 27, Issue 5

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/physiopathology ; France ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/physiopathology ; Pulmonary Embolism/virology ; SARS-CoV-2 ; Tomography, X-Ray Computed ; Travel
    Keywords covid19
    Language English
    Publishing date 2020-04-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taaa063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4120: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Molecular profile of non-small cell lung cancer in reunion Island.

    Moreau, Diane / Huchot, Eric / Foch, Emilie / Allou, Nathalie / Caumont, Charline / Merlio, Jean Philippe / Andre, Michel

    Respiratory medicine and research

    2022  Volume 82, Page(s) 100939

    Abstract: Background: In recent years, the discovery of predictive biomarkers has enabled the development of targeted therapies that have improved the prognosis of patients with non-small cell lung cancer (NSCLC). No data are available at present on the molecular ...

    Abstract Background: In recent years, the discovery of predictive biomarkers has enabled the development of targeted therapies that have improved the prognosis of patients with non-small cell lung cancer (NSCLC). No data are available at present on the molecular profile of NSCLC in Reunion Island, a French overseas department located in the Indian Ocean and characterized by an ethnically-mixed population.
    Method: This observational, retrospective, and multicenter study included all patients who were diagnosed with NSCLC in Reunion Island during 2 years and whose tumor specimens were sent for molecular analysis at Bordeaux University Hospital. The aim of the study was to determine the molecular profile of NSCLC in the Reunionese population, including the frequency of epidermal growth factor receptor (EGFR) mutation.
    Results: A total of 310 patients with NSCLC were screened for genetic mutations. Of these, 281 (91%) had adenocarcinoma, 207 (66%) were born in Reunion Island, 79 (25%) were never-smokers, and 109 (35%) were women. One hundred and seventy-eight (57%) patients had a genetic mutation. An EGFR mutation was detected in 69 patients (22%) of the 310 included patients. This mutation was detected in 23% of patients with adenocarcinoma, 40% of women, 55% of never-smokers, and 23% of patients born in Reunion Island.
    Conclusion: The frequency of EGFR mutation is high in the Reunionese population. This frequency is similar to that reported in Asia and may be explained by the history of migrations and ethnic mixing in Reunion Island. These findings suggest complex interactions between genetic and environmental factors in the carcinogenesis of NSCLC.
    MeSH term(s) Humans ; Female ; Male ; Carcinoma, Non-Small-Cell Lung/epidemiology ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Lung Neoplasms/epidemiology ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Retrospective Studies ; Reunion/epidemiology ; ErbB Receptors/genetics ; Adenocarcinoma
    Chemical Substances ErbB Receptors (EC 2.7.10.1)
    Language English
    Publishing date 2022-06-27
    Publishing country France
    Document type Observational Study ; Multicenter Study ; Journal Article
    ISSN 2590-0412
    ISSN (online) 2590-0412
    DOI 10.1016/j.resmer.2022.100939
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Pulmonary embolism in a returning traveller with COVID-19 pneumonia

    Foch, Emilie / Allou, Nathalie / Vitry, Thierry / Masse, Laurie / Allyn, Jérôme / Andre, Michel / Allou, Nicolas

    J. travel med

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #116724
    Database COVID19

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  4. Article: Pulmonary embolism in returning traveler with COVID-19 pneumonia

    Foch, Emilie / Allou, Nathalie / Vitry, Thierry / Masse, Laurie / Allyn, Jérôme / Andre, Michel / Allou, Nicolas

    J. travel med

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #116724
    Database COVID19

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  5. Article ; Online: Pulmonary embolism in a returning traveller with COVID-19 pneumonia

    Foch, Emilie / Allou, Nathalie / Vitry, Thierry / Masse, Laurie / Allyn, Jérôme / Andre, Michel / Allou, Nicolas

    Journal of Travel Medicine

    2020  Volume 27, Issue 5

    Abstract: Pulmonary embolism and COVID-19 ... ...

    Abstract Pulmonary embolism and COVID-19 pneumonia
    Keywords General Medicine ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taaa063
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4120: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Co-infection in patients with hypoxemic pneumonia due to COVID-19 in Reunion Island.

    Allou, Nicolas / Larsen, Kevin / Dubernet, Arthur / Traversier, Nicolas / Masse, Laurie / Foch, Emilie / Bruneau, Léa / Maillot, Adrien / André, Michel / Lagrange-Xelot, Marie / Allyn, Jérôme / Thomas, Vincent / Coolen-Allou, Nathalie

    Medicine

    2021  Volume 100, Issue 4, Page(s) e24524

    Abstract: Abstract: This study aimed to evaluate the incidence of co-infection with different types of pathogens in patients with hypoxemic pneumonia due to coronavirus disease 2019 (COVID-19) in Reunion Island.This observational study using a prospectively ... ...

    Abstract Abstract: This study aimed to evaluate the incidence of co-infection with different types of pathogens in patients with hypoxemic pneumonia due to coronavirus disease 2019 (COVID-19) in Reunion Island.This observational study using a prospectively collected database of hypoxemic pneumonia due to COVID-19 cases was conducted at Félix Guyon University Hospital in Reunion Island, France.Between 18 March 2020 and 15 April 2020, 156 patients were admitted to our hospital for COVID-19. A total of 36 patients had hypoxemic pneumonia (23.1%) due to COVID-19. Thirty of these cases (83.3%) were imported by travelers returning mainly from metropolitan France and Spain. Patients were screened for co-infection with other pathogens at admission: 31 (86.1%) by multiplex polymerase chain reaction (PCR) and 16 (44.4%) by cytobacteriological examination of sputum culture. Five patients (13.9%) were found to have co-infection: 1 with influenza virus A H1N1 (pdm09) associated with Branhamella catarrhalis, 1 with Streptococcus pneumoniae associated with Haemophilus influenzae, 1 with Human Coronavirus 229E, 1 with Rhinovirus, and 1 with methicillin-susceptible Staphylococcus aureus. Patients with co-infection had higher D-dimer levels than those without co-infection (1.36 [1.34-2.36] μg/mL vs 0.63 [0.51-1.12] μg/mL, P = .05).The incidence of co-infection in our cohort was higher than expected (13.9%). Three co-infections (with influenza virus A(H1N1) pdm09, Streptococcus pneumoniae, and Staphylococcus aureus) required specific treatment. Patients with hypoxemic pneumonia due to COVID-19 should be screened for co-infection using respiratory cultures or multiplex PCR. Whilst our study has a number of limitations, the results from our study suggest that in the absence of screening, patients should be commenced on treatment for co-infection in the presence of an elevated D-dimer.
    MeSH term(s) Adult ; COVID-19/epidemiology ; Coinfection/epidemiology ; Female ; France/epidemiology ; Humans ; Hypoxia ; Male ; Middle Aged ; Pneumonia/epidemiology ; Pneumonia/microbiology ; Retrospective Studies ; SARS-CoV-2
    Language English
    Publishing date 2021-01-27
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000024524
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.171: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Detection of Pulmonary Embolism in Returning Travelers with Hypoxemic Pneumonia due to COVID-19 in Reunion Island.

    Larsen, Kevin / Coolen-Allou, Nathalie / Masse, Laurie / Angelino, Alexandre / Allyn, Jérôme / Bruneau, Lea / Maillot, Adrien / Lagrange-Xelot, Marie / Vitry, Thierry / André, Michel / Travers, Jean Yves / Foch, Emilie / Allou, Nicolas

    The American journal of tropical medicine and hygiene

    2020  Volume 103, Issue 2, Page(s) 844–846

    Abstract: The aim of this study was to evaluate the occurrence of pulmonary embolism in returning travelers with hypoxemic pneumonia due to COVID-19. All returning travelers to Reunion Island with hypoxemic pneumonia due to COVID-19 underwent computed tomography ... ...

    Abstract The aim of this study was to evaluate the occurrence of pulmonary embolism in returning travelers with hypoxemic pneumonia due to COVID-19. All returning travelers to Reunion Island with hypoxemic pneumonia due to COVID-19 underwent computed tomography pulmonary angiography (CTPA) and were included in the cohort. Thirty-five patients were returning travelers with hypoxemic pneumonia due to COVID-19 and had recently returned from one of the countries most affected by the COVID-19 outbreak (mainly from France and Comoros archipelago). Five patients (14.3%) were found to have pulmonary embolism and two (5.9%) were incidentally found to have deep vein thrombosis on CTPA. Patients with pulmonary embolism or deep vein thrombosis had higher D-dimer levels than those without pulmonary embolism or deep vein thrombosis (
    MeSH term(s) Aged ; Aged, 80 and over ; Angiography ; Betacoronavirus ; COVID-19 ; Comoros ; Coronavirus Infections/complications ; Coronavirus Infections/diagnostic imaging ; Female ; Fibrin Fibrinogen Degradation Products/analysis ; France ; Humans ; Hypoxia/virology ; Lung/diagnostic imaging ; Lung/pathology ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnostic imaging ; Pulmonary Embolism/diagnostic imaging ; Pulmonary Embolism/virology ; Reunion ; SARS-CoV-2 ; Tomography, X-Ray Computed ; Travel ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/virology
    Chemical Substances Fibrin Fibrinogen Degradation Products ; fibrin fragment D
    Keywords covid19
    Language English
    Publishing date 2020-07-01
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.20-0597
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.61: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Detection of Pulmonary Embolism in Returning Travelers with Hypoxemic Pneumonia due to COVID-19 in Reunion Island

    Larsen, Kevin / Coolen-Allou, Nathalie / Masse, Laurie / Angelino, Alexandre / Allyn, Jérôme / Bruneau, Lea / Maillot, Adrien / Lagrange-Xelot, Marie / Vitry, Thierry / André, Michel / Travers, Jean Yves / Foch, Emilie / Allou, Nicolas

    Am J Trop Med Hyg

    Abstract: The aim of this study was to evaluate the occurrence of pulmonary embolism in returning travelers with hypoxemic pneumonia due to COVID-19. All returning travelers to Reunion Island with hypoxemic pneumonia due to COVID-19 underwent computed tomography ... ...

    Abstract The aim of this study was to evaluate the occurrence of pulmonary embolism in returning travelers with hypoxemic pneumonia due to COVID-19. All returning travelers to Reunion Island with hypoxemic pneumonia due to COVID-19 underwent computed tomography pulmonary angiography (CTPA) and were included in the cohort. Thirty-five patients were returning travelers with hypoxemic pneumonia due to COVID-19 and had recently returned from one of the countries most affected by the COVID-19 outbreak (mainly from France and Comoros archipelago). Five patients (14.3%) were found to have pulmonary embolism and two (5.9%) were incidentally found to have deep vein thrombosis on CTPA. Patients with pulmonary embolism or deep vein thrombosis had higher D-dimer levels than those without pulmonary embolism or deep vein thrombosis (P = 0.04). Returning travelers with hypoxemic pneumonia due to COVID-19 should be systematically screened for pulmonary embolism.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #630202
    Database COVID19

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  9. Article ; Online: A comprehensive strategy for the early treatment of COVID-19 with azithromycin/hydroxychloroquine and/or corticosteroids: Results of a retrospective observational study in the French overseas department of Réunion Island.

    Dubernet, Arthur / Larsen, Kevin / Masse, Laurie / Allyn, Jérôme / Foch, Emilie / Bruneau, Lea / Maillot, Adrien / Lagrange-Xelot, Marie / Thomas, Vincent / Jaffar-Bandjee, Marie-Christine / Gauzere, Loraine / Raffray, Loic / Borsu, Karine / Dibernardo, Servane / Renaud, Stéphane / André, Michel / Moreau, Diane / Jabot, Julien / Coolen-Allou, Nathalie /
    Allou, Nicolas

    Journal of global antimicrobial resistance

    2020  Volume 23, Page(s) 1–3

    Abstract: Background: This study aimed to evaluate the prognosis of COVID-19 patients in Reunion Island, with a particular focus on the management of patients with hypoxemic pneumonia.: Methods: This retrospective observational study was conducted from 11 ... ...

    Abstract Background: This study aimed to evaluate the prognosis of COVID-19 patients in Reunion Island, with a particular focus on the management of patients with hypoxemic pneumonia.
    Methods: This retrospective observational study was conducted from 11 March to 17 April 2020 at the only hospital authorized to manage patients with COVID-19 in Reunion Island.
    Results: Over the study period, 164 out of 398 patients (41.2%) infected with COVID-19 were admitted to Félix Guyon University Hospital. Of these, 36 (22%) developed hypoxemic pneumonia. Patients with hypoxemic pneumonia were aged 66 [56-77] years, 69% were male and 33% had hypertension. Ten patients (27.8%) were hospitalized in intensive care unit (ICU). Hydroxychloroquine/azithromycin treatment was associated with a lower ICU admission rate (P=0.008). None of the 6 patients treated with corticosteroids were hospitalized in ICU (P=0.16). There were no deaths at follow up (minimum 80 days).
    Conclusions: Despite the risk profile of COVID-19 patients with severe hypoxemic pneumonia, the mortality rate of the disease in Reunion Island was 0%. This may be due to the care bundle used in our hospital (early hospitalisation, treatment with hydroxychloroquine/azithromycin and/or corticosteroids, non-invasive respiratory support, etc).
    MeSH term(s) Adrenal Cortex Hormones/administration & dosage ; Aged ; Azithromycin/administration & dosage ; COVID-19/drug therapy ; COVID-19/virology ; Drug Therapy, Combination ; Female ; Hospitalization ; Humans ; Hydroxychloroquine/administration & dosage ; Intensive Care Units ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Retrospective Studies ; Reunion ; SARS-CoV-2/isolation & purification
    Chemical Substances Adrenal Cortex Hormones ; Hydroxychloroquine (4QWG6N8QKH) ; Azithromycin (83905-01-5)
    Keywords covid19
    Language English
    Publishing date 2020-08-20
    Publishing country Netherlands
    Document type Journal Article ; Observational Study
    ZDB-ID 2710046-7
    ISSN 2213-7173 ; 2213-7165
    ISSN (online) 2213-7173
    ISSN 2213-7165
    DOI 10.1016/j.jgar.2020.08.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A comprehensive strategy for the early treatment of COVID-19 with azithromycin/hydroxychloroquine and/or corticosteroids

    Dubernet, Arthur / Larsen, Kevin / Masse, Laurie / Allyn, Jérôme / Foch, Emilie / Bruneau, Lea / Maillot, Adrien / Lagrange-Xelot, Marie / Thomas, Vincent / Jaffar-Bandjee, Marie-Christine / Gauzere, Loraine / Raffray, Loic / Borsu, Karine / Dibernardo, Servane / Renaud, Stéphane / André, Michel / Moreau, Diane / Jabot, Julien / Coolen-Allou, Nathalie /
    Allou, Nicolas

    Journal of Global Antimicrobial Resistance

    Results of a retrospective observational study in the French overseas department of Réunion Island

    2020  Volume 23, Page(s) 1–3

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2710046-7
    ISSN 2213-7173 ; 2213-7165
    ISSN (online) 2213-7173
    ISSN 2213-7165
    DOI 10.1016/j.jgar.2020.08.001
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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