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  1. Book ; Online: The Future Of The Large Hadron Collider

    Bruning, Oliver / Klein, Max / Rossi, Lucio / Spagnolo, Paolo

    A Super-accelerator With Multiple Possible Lives

    2024  

    Keywords Industrial applications of scientific research & technological innovation ; Physics;Particle Physics / High Energy Physics / Quantum Fields
    Language English
    Size 1 electronic resource (455 pages)
    Publisher World Scientific Publishing Company
    Publishing place Singapore
    Document type Book ; Online
    Note English
    HBZ-ID HT030613252
    ISBN 9789811280191 ; 9811280193
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Deep Learning Applications

    Luigi Mazzeo, Pier / Spagnolo, Paolo

    2021  

    Keywords Machine learning ; neural networks, machine learning, artificial intelligence, big data, risk assessment, security
    Language English
    Size 1 electronic resource (214 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030647044
    ISBN 9781839623769 ; 1839623764
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Visual Object Tracking with Deep Neural Networks

    Luigi Mazzeo, Pier / Ramakrishnan, Srinivasan / Spagnolo, Paolo

    2019  

    Keywords Artificial intelligence ; Neural networks & fuzzy systems
    Size 1 electronic resource (206 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021049005
    ISBN 9781789851427 ; 1789851424
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online ; E-Book: Pulmonary manifestations of systemic diseases

    Wells, Athol U. / Wuyts, Wim A. / Cottin, Vincent / Spagnolo, Paolo

    (ERS monograph)

    2019  

    Author's details edited by Wim A. Wuyts, Vincent Cottin, Paolo Spagnolo and Athol U. Wells
    Series title ERS monograph
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xiv, 419 Seiten)
    Publisher European Respiratory Society
    Publishing place Sheffield
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020389757
    ISBN 978-1-84984-112-2 ; 9781849841115 ; 1-84984-112-8 ; 184984111X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: A Long and Winding Road: Drug Development in Idiopathic Pulmonary Fibrosis.

    Spagnolo, Paolo / Maher, Toby M

    American journal of respiratory and critical care medicine

    2024  Volume 209, Issue 9, Page(s) 1072–1073

    MeSH term(s) Idiopathic Pulmonary Fibrosis/drug therapy ; Humans ; Drug Development
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article ; Editorial
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202402-0290VP
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh II Zs.80: Show issues Location:
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  6. Article: Editorial: Epidemiology and risk factors for interstitial lung diseases.

    Jeganathan, Niranjan / Corte, Tamera J / Spagnolo, Paolo

    Frontiers in medicine

    2024  Volume 11, Page(s) 1384825

    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2024.1384825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Sarcoidosis.

    Spagnolo, Paolo / Bernardinello, Nicol

    Immunology and allergy clinics of North America

    2023  Volume 43, Issue 2, Page(s) 259–272

    Abstract: Sarcoidosis is a disease of unknown cause characterized by granulomatous inflammation. Although the lung is almost universally involved, any organ can be affected. Complex pathogenesis and protean clinical manifestations are additional features of the ... ...

    Abstract Sarcoidosis is a disease of unknown cause characterized by granulomatous inflammation. Although the lung is almost universally involved, any organ can be affected. Complex pathogenesis and protean clinical manifestations are additional features of the disease. The diagnosis is one of exclusion, although the presence of noncaseating granulomas at disease sites is a prerequisite in most cases. The management of sarcoidosis requires a multidisciplinary approach, particularly when the heart, the brain, or the eyes are involved. The paucity of effective therapies and the lack of reliable predictors of disease behavior greatly contribute to making sarcoidosis a challenging disease to manage.
    MeSH term(s) Humans ; Sarcoidosis/diagnosis ; Sarcoidosis/therapy ; Sarcoidosis/pathology ; Granuloma/diagnosis ; Granuloma/etiology ; Granuloma/therapy ; Lung/pathology ; Diagnosis, Differential
    Language English
    Publishing date 2023-03-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92606-1
    ISSN 1557-8607 ; 0889-8561
    ISSN (online) 1557-8607
    ISSN 0889-8561
    DOI 10.1016/j.iac.2023.01.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Se 710: Show issues Location:
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  8. Article ; Online: Recent advances in the genetics of idiopathic pulmonary fibrosis.

    Spagnolo, Paolo / Lee, Joyce S

    Current opinion in pulmonary medicine

    2023  Volume 29, Issue 5, Page(s) 399–405

    Abstract: Purpose of review: Genetics contributes substantially to the susceptibility to idiopathic pulmonary fibrosis (IPF). Genetic studies in sporadic and familial disease have identified several IPF-associated variants, mainly in telomere-related and ... ...

    Abstract Purpose of review: Genetics contributes substantially to the susceptibility to idiopathic pulmonary fibrosis (IPF). Genetic studies in sporadic and familial disease have identified several IPF-associated variants, mainly in telomere-related and surfactant protein genes.Here, we review the most recent literature on genetics of IPF and discuss how it may contribute to disease pathogenesis.
    Recent findings: Recent studies implicate genes involved in telomere maintenance, host defence, cell growth, mammalian target of rapamycin signalling, cell-cell adhesion, regulation of TGF-β signalling and spindle assembly as biological processes involved in the pathogenesis of IPF. Both common and rare genetic variants contribute to the overall risk of IPF; however, while common variants (i.e. polymorphisms) account for most of the heritability of sporadic disease, rare variants (i.e. mutations), mainly in telomere-related genes, are the main contributors to the heritability of familial disease. Genetic factors are likely to also influence disease behaviour and prognosis. Finally, recent data suggest that IPF shares genetic associations - and probably some pathogenetic mechanisms - with other fibrotic lung diseases.
    Summary: Common and rare genetic variants are associated with susceptibility and prognosis of IPF. However, many of the reported variants fall in noncoding regions of the genome and their relevance to disease pathobiology remains to be elucidated.
    MeSH term(s) Humans ; Idiopathic Pulmonary Fibrosis/genetics ; Mutation ; Pulmonary Surfactants ; Telomerase/genetics ; Signal Transduction/genetics
    Chemical Substances Pulmonary Surfactants ; Telomerase (EC 2.7.7.49)
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1285505-4
    ISSN 1531-6971 ; 1070-5287 ; 1078-1641
    ISSN (online) 1531-6971
    ISSN 1070-5287 ; 1078-1641
    DOI 10.1097/MCP.0000000000000989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4900: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  9. Article: Editorial: Immune-mediated lung injury.

    Karampitsakos, Theodoros / Spagnolo, Paolo / Tzouvelekis, Argyris

    Frontiers in medicine

    2023  Volume 10, Page(s) 1292074

    Language English
    Publishing date 2023-11-03
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1292074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: On Target: CYFRA 21-1 as an Idiopathic Pulmonary Fibrosis Biomarker.

    Spagnolo, Paolo / Oldham, Justin M

    American journal of respiratory and critical care medicine

    2022  Volume 205, Issue 12, Page(s) 1376–1377

    MeSH term(s) Antigens, Neoplasm ; Biomarkers ; Humans ; Idiopathic Pulmonary Fibrosis/diagnosis ; Keratin-19 ; Prospective Studies
    Chemical Substances Antigens, Neoplasm ; Biomarkers ; Keratin-19 ; antigen CYFRA21.1
    Language English
    Publishing date 2022-04-21
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202203-0474ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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