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Article ; Online: Respiratory considerations in patients with neuromuscular disorders.

Patel, Nina / Howard, Ileana M / Baydur, Ahmet

2023 Volume 68, Issue 2, Page(s) 122–141

Abstract: Patients with neuromuscular disorders (NMDs) develop respiratory impairment as muscles weaken. Ensuing complications include reductions in lung volume, compliance, and cough ability and increased risk for lung infections. Sleep disordered breathing ... ...

Abstract	Patients with neuromuscular disorders (NMDs) develop respiratory impairment as muscles weaken. Ensuing complications include reductions in lung volume, compliance, and cough ability and increased risk for lung infections. Sleep disordered breathing results from weakened upper airway muscles and/or impaired central ventilatory control systems. Evaluation includes measurement of seated and supine vital capacity (VC) and respiratory muscle strength. Assisted cough techniques facilitate airway clearance. The decision to initiate assisted ventilation is multifactorial, and may include consideration of patient symptoms, spirometry, pulmonary pressures, sleep studies or blood gas values. Most patients prefer noninvasive ventilation to enhance mobility and independence. Tracheostomy is indicated when bulbar function is impaired and cough assist measures fail to clear the airway. Technological advances in respiratory support have improved quality of life and longevity. Home care is the best option for most patients but remains a challenge, especially for caregivers with regard to physical, emotional, and financial implications, as well as social, administrative, and insurance concerns.
MeSH term(s)	Humans ; Cough/etiology ; Quality of Life ; Neuromuscular Diseases/complications ; Neuromuscular Diseases/therapy ; Respiratory Insufficiency/therapy ; Respiratory Insufficiency/complications ; Respiratory Muscles
Language	English
Publishing date	2023-05-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	438353-9
ISSN	1097-4598 ; 0148-639X
ISSN (online)	1097-4598
ISSN	0148-639X
DOI	10.1002/mus.27845
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Zs.A 1449: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 551: Show issues

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Article ; Online: Management and support of patients with fibrosing interstitial lung diseases.

Barbera, Tyonn / Davila, Lesley / Patel, Nina M

The Nurse practitioner

2021 Volume 46, Issue 7, Page(s) 39–44

Abstract: Abstract: Fibrosing interstitial lung diseases have a variable clinical course. Regular monitoring is important to assess disease progression and inform patient care and counseling. NPs play a key role in helping patients understand their disease and ... ...

Abstract	Abstract: Fibrosing interstitial lung diseases have a variable clinical course. Regular monitoring is important to assess disease progression and inform patient care and counseling. NPs play a key role in helping patients understand their disease and its treatment and manage the adverse reactions of pharmacologic therapies.
MeSH term(s)	Disease Progression ; Humans ; Idiopathic Pulmonary Fibrosis/nursing ; Lung Diseases, Interstitial/nursing ; Nurse Practitioners ; Nurse-Patient Relations ; Nursing Diagnosis
Language	English
Publishing date	2021-06-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	604085-8
ISSN	1538-8662 ; 0361-1817
ISSN (online)	1538-8662
ISSN	0361-1817
DOI	10.1097/01.NPR.0000743332.64602.aa
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Zs.B 2398: Show issues

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Article ; Online: Botanical Briefs: Neem Oil (Azadirachta indica).

Patel, Nina / Knabel, Michael / Speiser, Jodi

Cutis

2024 Volume 113, Issue 1, Page(s) 22–24

Abstract: Azadirachta indica, commonly known as neem, has many uses as a natural remedy. We review and discuss the pharmacologic, biologic, and medicinal properties of neem in disease management. We also report a rare clinical case of a 77-year-old man who ... ...

Abstract	Azadirachta indica, commonly known as neem, has many uses as a natural remedy. We review and discuss the pharmacologic, biologic, and medicinal properties of neem in disease management. We also report a rare clinical case of a 77-year-old man who presented with a hypopigmented rash on the lower back, bilateral flanks, and buttocks after 6 months of repeated application of neem oil to treat persistent arthritis and lower back pain.
MeSH term(s)	Male ; Humans ; Aged ; Azadirachta ; Glycerides/pharmacology ; Terpenes/pharmacology ; Plant Extracts
Chemical Substances	neem oil (4DKJ9B3K2T) ; Glycerides ; Terpenes ; Plant Extracts
Language	English
Publishing date	2024-03-13
Publishing country	United States
Document type	Case Reports ; Review ; Journal Article
ZDB-ID	391840-3
ISSN	2326-6929 ; 0011-4162 ; 0151-9522
ISSN (online)	2326-6929
ISSN	0011-4162 ; 0151-9522
DOI	10.12788/cutis.0928
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Zs.B 1315: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 44: Show issues

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Article: Best Practice Recommendations for Stroke Vascular Imaging During Iodinated Contrast Shortage.

Bhole, Rohini / Solenski, Nina J / Donahue, Joseph H / Kellogg, Ryan T / Roach, Necrisha N / Chapman, Sherita N / Worrall, Bradford B / Evans, Avery J / Patel, Sohil H / Mukherjee, Sugoto / Park, Min S / Southerland, Andrew M

Neurology. Clinical practice

2023 Volume 13, Issue 2, Page(s) e200119

Abstract: ... GE ... ...

Abstract	GE Healthcare
Language	English
Publishing date	2023-03-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2645818-4
ISSN	2163-0933 ; 2163-0402
ISSN (online)	2163-0933
ISSN	2163-0402
DOI	10.1212/CPJ.0000000000200119
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Article ; Online: Evaluating the comparability of patient-level social risk data extracted from electronic health records: A systematic scoping review.

Linfield, Gaia H / Patel, Shyam / Ko, Hee Joo / Lacar, Benjamin / Gottlieb, Laura M / Adler-Milstein, Julia / Singh, Nina V / Pantell, Matthew S / De Marchis, Emilia H

Health informatics journal

2023 Volume 29, Issue 3, Page(s) 14604582231200300

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Humans ; Electronic Health Records ; Social Support
Language	English
Publishing date	2023-09-07
Publishing country	England
Document type	Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S. ; Research Support, N.I.H., Extramural
ZDB-ID	2213115-2
ISSN	1741-2811 ; 1460-4582
ISSN (online)	1741-2811
ISSN	1460-4582
DOI	10.1177/14604582231200300
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Article ; Online: Preoperative Evaluation of Patients With Interstitial Lung Disease.

Patel, Nina M / Kulkarni, Tejaswini / Dilling, Daniel / Scholand, Mary Beth

Chest

2019 Volume 156, Issue 5, Page(s) 826–833

MeSH term(s)	Acute Disease ; Humans ; Lung Diseases, Interstitial/diagnosis ; Lung Diseases, Interstitial/surgery ; Pneumonectomy ; Preoperative Care/methods ; Risk Factors
Language	English
Publishing date	2019-06-29
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1032552-9
ISSN	1931-3543 ; 0012-3692
ISSN (online)	1931-3543
ISSN	0012-3692
DOI	10.1016/j.chest.2019.05.028
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Zs.MO 349: Show issues

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Article ; Online: Assessing Knowledge, Usage, and Perceptions of the Frazier Free Water Protocol: A Pilot Study.

Kokush, Emily M / Patel, Radhika / Boardingham, Christine E / Rothman, Brooke F / Ward, Jan / McKay, Ondrea A / Yonclas, Peter / Glass, Nina E

The Journal of surgical research

2023 Volume 293, Page(s) 381–388

Abstract: Introduction: Dysphagia is very common among hospitalized patients and is associated with increased length of hospital stay, morbidity, and mortality. Diet restrictions for dysphagia cause dehydration and discontent. The Frazier Free Water Protocol ( ... ...

Abstract	Introduction: Dysphagia is very common among hospitalized patients and is associated with increased length of hospital stay, morbidity, and mortality. Diet restrictions for dysphagia cause dehydration and discontent. The Frazier Free Water Protocol (FFWP) was developed to improve hydration and quality of life in dysphagia patients by establishing the safety of allowing sips of water between meals. Despite these potential benefits, we hypothesized that the FFWP is not widely utilized. We sought to determine barriers to utilization by assessing the familiarity, usage, and perceptions of the FFWP among health-care providers at our institution. Methods: We distributed an anonymous questionnaire to a convenience sample of nurses in the hospital during daily huddles. The questionnaire was adapted from a validated framework to assess provider acceptability of health-care interventions. Results: Of the 66 surveys distributed, we had 58 completed (88%). Only 10 nurses (17%) had heard of the "FFWP" by name. For those that were familiar with the indications, benefits, and risks of giving free water to patients with dysphagia (n = 18), less than half (39%) reported doing so. No nurses that had less than 10 y of patient care experience gave water to dysphagia patients, even if they knew the indications, benefits, and risks. Similarly, less than a fifth (19%) of all nurses surveyed were comfortable giving water to dysphagia patients, but comfort increased for some if the protocol was recommended by a speech-language pathologist (33%) or physician (13%). Nursing experience of >10 y or in intensive care settings did not yield significant differences in knowledge, usage, or comfort level than those with less years or nonintensive care experience, respectively. Conclusions: Nurses are essential to the implementation of the FFWP, yet many are unfamiliar and uncomfortable with utilizing it. Education about the protocol is necessary to improve patient outcomes and quality of life. We plan to provide targeted education about the FFWP as well as assess other members of the health-care team, in an attempt to increase utilization of the protocol and improve dysphagia management.
MeSH term(s)	Humans ; Deglutition Disorders/etiology ; Deglutition Disorders/therapy ; Pilot Projects ; Quality of Life ; Delivery of Health Care ; Water
Chemical Substances	Water (059QF0KO0R)
Language	English
Publishing date	2023-10-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	80170-7
ISSN	1095-8673 ; 0022-4804
ISSN (online)	1095-8673
ISSN	0022-4804
DOI	10.1016/j.jss.2023.08.034
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Zs.A 178: Show issues

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Article ; Online: Hypersensitivity pneumonitis: Airway-centered pulmonary fibrosis on chest CT.

Capaccione, K M / Austin, John H M / Saqi, Anjali / Patel, Nina / Padilla, Maria / Salvatore, Mary M

Respiratory investigation

2021 Volume 59, Issue 6, Page(s) 845–848

Abstract: Background: To evaluate the chest CT appearance of patients with a clinicopathologic diagnosis of hypersensitivity pneumonia.: Methods: IRB approval was obtained for a retrospective review of patients with a preoperative CT scan, a surgical pathology ...

Abstract	Background: To evaluate the chest CT appearance of patients with a clinicopathologic diagnosis of hypersensitivity pneumonia. Methods: IRB approval was obtained for a retrospective review of patients with a preoperative CT scan, a surgical pathology report from a transbronchial biopsy or wedge resection consistent with hypersensitivity pneumonitis, and a pulmonary consultation, which also supported the diagnosis. The pathology report was evaluated for granulomas, airway-centered fibrosis, microscopic honeycombing, and fibroblast foci. The medical records were reviewed for any known antigen exposure. Patients were separated into two groups; those with and without a known antigen exposure. The CT scans were assessed for distribution of fibrosis: upper lobe or lower lobe predominance, airway-centered versus peripheral distribution, three-density pattern, and honeycombing. Results: 264 pathology reports included the term chronic hypersensitivity pneumonitis (CHP). Thirty-eight of the patients had a pulmonologist who gave the patient a working diagnosis of CHP. The average age of these patients was 64 years, and 21/38 were women. Seventeen of the 38 patients had at least one antigen exposure described in the medical records. All the patients had fibrosis along the airways on chest CT. Both known antigen exposure and no known antigen patients had upper and lower lung-predominant fibrosis. There were more patients with hiatal hernias in the unknown antigen group. Honeycombing was an uncommon finding. Conclusion: Airway-centered fibrosis was present on chest CT in all 38 patients with CHP (100%), with or without known antigen exposure.
MeSH term(s)	Alveolitis, Extrinsic Allergic/diagnostic imaging ; Female ; Humans ; Lung/diagnostic imaging ; Middle Aged ; Pulmonary Fibrosis/diagnostic imaging ; Retrospective Studies ; Tomography, X-Ray Computed
Language	English
Publishing date	2021-08-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2660821-2
ISSN	2212-5353 ; 2212-5345
ISSN (online)	2212-5353
ISSN	2212-5345
DOI	10.1016/j.resinv.2021.06.011
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Article: Interstitial Lung Disease in Systemic Sclerosis: Focus on Early Detection and Intervention.

Fischer, Aryeh / Patel, Nina M / Volkmann, Elizabeth R

Open access rheumatology : research and reviews

2019 Volume 11, Page(s) 283–307

Abstract: Systemic sclerosis (SSc) is a progressive and often devastating disease characterized by autoimmune dysfunction, vasculopathy, and fibrosis. Interstitial lung disease (ILD) is identified in the majority of patients with SSc and is the leading cause of ... ...

Abstract	Systemic sclerosis (SSc) is a progressive and often devastating disease characterized by autoimmune dysfunction, vasculopathy, and fibrosis. Interstitial lung disease (ILD) is identified in the majority of patients with SSc and is the leading cause of SSc-related mortality. Although clinical manifestations and ILD severity vary among patients, lung function typically declines to the greatest extent during the first 3-4 years after disease onset. We aim to provide an overview of SSc-associated ILD (SSc-ILD) with a focus on current and emerging tools for early diagnosis of ILD and current and novel treatments under investigation. Early detection of ILD provides the opportunity for early therapeutic intervention, which could improve patient outcomes. Thoracic high-resolution computed tomography is the most effective method of identifying ILD in patients with SSc; it enables detection of mild lung abnormalities and plays an important role in monitoring disease progression. Cyclophosphamide and mycophenolate mofetil are the most commonly prescribed treatments for SSc-ILD. Recently, nintedanib (an antifibrotic) was approved by the Food and Drug Administration for patients with SSc-ILD; it is indicated for slowing the rate of decline in pulmonary function. However, there is a need for additional effective and well-tolerated disease-modifying therapy. Ongoing studies are evaluating other antifibrotics and novel agents. We envision that early detection of lung involvement, combined with the emergence and integration of novel therapies, will lead to improved outcomes in patients with SSc-ILD.
Language	English
Publishing date	2019-12-09
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2508169-X
ISSN	1179-156X
ISSN	1179-156X
DOI	10.2147/OARRR.S226695
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Article ; Online: Vaccine response after pneumococcal vaccination in allogeneic hematopoietic stem cell transplant recipients.

Cheplowitz, Halle / Patel, Nimish / Kim, Alexander / Logan, Cathy / Law, Nancy / Koura, Divya / Haste, Nina / Medley, Katherine / Trinh, Julie / Sanders, Tyler / Taremi, Mahnaz / Saunders, Ila M

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

2023 Volume 30, Issue 1, Page(s) 15–18

Abstract: Current guidelines for vaccination in allogeneic hematopoietic stem cell transplant (HCT) recipients recommend initiation of pneumococcal vaccination series three to six months post-HCT, with most data supporting initiation at six months due to a more ... ...

Abstract	Current guidelines for vaccination in allogeneic hematopoietic stem cell transplant (HCT) recipients recommend initiation of pneumococcal vaccination series three to six months post-HCT, with most data supporting initiation at six months due to a more robust immune response. This single-center, retrospective, observational chart review aimed to evaluate the impact of initiating the pneumococcal vaccine series at three months post-HCT compared to six months post-HCT. The primary endpoints were defined as a percentage of patients with a serologic response of >1 and >1.3 µg/mL for over 50% of the defined serotypes. Outcomes showed no difference in immunologic response between the two groups.
MeSH term(s)	Humans ; Hematopoietic Stem Cell Transplantation ; Pneumococcal Infections/prevention & control ; Pneumococcal Vaccines ; Retrospective Studies ; Vaccination
Chemical Substances	Pneumococcal Vaccines
Language	English
Publishing date	2023-03-22
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	1330764-2
ISSN	1477-092X ; 1078-1552
ISSN (online)	1477-092X
ISSN	1078-1552
DOI	10.1177/10781552231165733
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Zs.A 4488: Show issues

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