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  1. AU=Hamdani Muhammad Afzal
  2. AU="Wen, O"
  3. AU="de Oliveira, Luciana Maia Nogueira"
  4. AU="Sanabria, Mauricio"
  5. AU="Tronnier, Michael"
  6. AU="Yu, Yaonan"
  7. AU="Gradl, W"
  8. AU="Grossklags, Jens"
  9. AU="Andreas M. Köster"
  10. AU="Diana Karolina Maniak"
  11. AU="Cahuana-Hurtado, Lucero"
  12. AU="Ebert, Christoph"
  13. AU="Köhler, Matthias"
  14. AU=Fitzgerald Amelia Lucy AU=Fitzgerald Amelia Lucy
  15. AU="Yang, Charles"
  16. AU="Fraser, Alice j"
  17. AU=MacKenzie James A
  18. AU=Guettari Moez AU=Guettari Moez
  19. AU=McLeod Carolyn
  20. AU="Patel P.M"
  21. AU="Patel N.M"
  22. AU="Naganawa, Mika"
  23. AU="Viecelli, Claudio"
  24. AU=Valls Joan
  25. AU="Yang, Qizhang"
  26. AU=Wilt Timothy J
  27. AU="Dene R. Littler" AU="Dene R. Littler"
  28. AU="Petrenko, Andrei"
  29. AU=Valentino Kristin
  30. AU=Swash M
  31. AU="Adedipe, Ifeoluwa"
  32. AU=Shen Hongcheng
  33. AU="Padhy, Biswajit"
  34. AU="Kruglikov, Alibek"
  35. AU="Tasu, Jean Pierre"
  36. AU="Floate, Kevin D"
  37. AU="Mark Rijpkema"
  38. AU="Gjeloshi, Klodian"
  39. AU="Lucie Beaudoin"

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  1. Artikel ; Online: Behcet's Disease Presenting With Life Threatening Manifestation Of Cerebral Venous Thrombosis.

    Naveed, Ushna / Iqbal, Aneela / Hamdani, Muhammad Afzal / Butt, Mujeeb-Ur-Rehman Abid / Ashraf, Muhammad Atif

    Journal of Ayub Medical College, Abbottabad : JAMC

    2020  Band 32, Heft 1, Seite(n) 124–126

    Abstract: Behcet's disease (BD) presents as uncommon inflammatory disorder involving multiple systems, identified by longstanding relapsing path. Its chief manifestations are oral and genital ulcers together with involvement of the eyes, skin and joints. ... ...

    Abstract Behcet's disease (BD) presents as uncommon inflammatory disorder involving multiple systems, identified by longstanding relapsing path. Its chief manifestations are oral and genital ulcers together with involvement of the eyes, skin and joints. Neurological and vascular complications are significant. We report a case of a twenty-four years old young male who presented with headache, fever, and vomiting along with decreased vision; and repeated oral and genital ulcers. Diagnosis of BD complicated with cerebral venous thrombosis (CVT) was made. He was treated with corticosteroids, immunosuppression therapy and colchicine along with anticoagulation therapy. He responded well to the given treatment. Cerebral venous thrombosis complications in with BD can lead to serious consequences. Early recognition and treatment may lessen poor outcomes.
    Mesh-Begriff(e) Adult ; Behcet Syndrome/complications ; Behcet Syndrome/diagnosis ; Humans ; Intracranial Thrombosis/diagnosis ; Intracranial Thrombosis/etiology ; Male ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2020-06-16
    Erscheinungsland Pakistan
    Dokumenttyp Case Reports
    ZDB-ID 2192473-9
    ISSN 1819-2718 ; 1025-9589
    ISSN (online) 1819-2718
    ISSN 1025-9589
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Macrophage Activation Syndrome Associated With Adult Onset Still's Disease.

    Gulzar, Madeeha / Sabir, Ali / Hamdani, Muhammad Afzal / Saadia, Asma

    Journal of Ayub Medical College, Abbottabad : JAMC

    2018  Band 30, Heft 2, Seite(n) 289–292

    Abstract: Macrophage activation syndrome (MAS) is a potentially lethal complication of chronic rheumatological conditions like ankylosing spondylitis, rheumatoid arthritis, and adult-onset Still's disease (AOSD). It is a multisystem inflammatory syndrome caused by ...

    Abstract Macrophage activation syndrome (MAS) is a potentially lethal complication of chronic rheumatological conditions like ankylosing spondylitis, rheumatoid arthritis, and adult-onset Still's disease (AOSD). It is a multisystem inflammatory syndrome caused by immense cytokine release from activated lymphocytes and macrophages. We give an account of the incidence of a twenty years old Asian girl suffering from non-remitting fever and an evanescent rash for last ten weeks. Physical examination and laboratory work-up suggested high grade fever, pancytopenia, hyperferritinemia, hypertriglyceridemia, hypofibrinogenemia and impaired liver function. Bone marrow biopsy was also done. It showed active hemophagocytosis. She was diagnosed as a case of Macrophage Activation Syndrome associated with Adult Onset Still's disease. She was treated with high dose steroids and cyclosporine and recovered completely.
    Mesh-Begriff(e) Biopsy ; Bone Marrow Cells/pathology ; Cytokines/blood ; Female ; Humans ; Macrophage Activation Syndrome/blood ; Macrophage Activation Syndrome/diagnosis ; Macrophage Activation Syndrome/etiology ; Still's Disease, Adult-Onset/complications ; Still's Disease, Adult-Onset/diagnosis ; Young Adult
    Chemische Substanzen Cytokines
    Sprache Englisch
    Erscheinungsdatum 2018-06-24
    Erscheinungsland Pakistan
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 2192473-9
    ISSN 1819-2718 ; 1025-9589
    ISSN (online) 1819-2718
    ISSN 1025-9589
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 6109: Hefte anzeigen Standort:
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  3. Artikel ; Online: Squamous Cell Carcinoma Arising in Background of Mature Cystic Teratoma.

    Zubair, Muhammad / Hashmi, Shoaib Naiyar / Afzal, Saeed / Muhammad, Iqbal / Ud Din, Hafeez / Hamdani, Syed Naeem Raza

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2016  Band 26, Heft 11, Seite(n) 929–930

    Abstract: Mature cystic teratoma of ovary is a common benign adnexal tumor in females. Malignant transformation in a mature cystic teratoma of the ovary occurs in only 1 - 2% of cases. Most common malignant transformation is squamous cell carcinoma (70-80% of ... ...

    Abstract Mature cystic teratoma of ovary is a common benign adnexal tumor in females. Malignant transformation in a mature cystic teratoma of the ovary occurs in only 1 - 2% of cases. Most common malignant transformation is squamous cell carcinoma (70-80% of cases), occurring mostly in postmenopausal women with large sized cysts. Here, we report a case of 46-year lady who presented with pain in lower abdomen. Ultrasound and CT scan revealed complex adnexal mass measuring 16x9 cm. Size and older age of the patients should be regarded as important predictors of malignant transformation in mature cystic teratoma. Adequate sampling followed by histopathological examination has important role in diagnosis of such rare tumor.
    Mesh-Begriff(e) Biomarkers, Tumor/blood ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/surgery ; Cell Transformation, Neoplastic ; Dermoid Cyst/pathology ; Dermoid Cyst/surgery ; Female ; Humans ; Hysterectomy ; Middle Aged ; Neoplasms, Multiple Primary/pathology ; Ovarian Neoplasms/pathology ; Ovarian Neoplasms/surgery ; Ovariectomy ; Prognosis ; Salpingectomy ; Teratoma/pathology ; Treatment Outcome
    Chemische Substanzen Biomarkers, Tumor
    Sprache Englisch
    Erscheinungsdatum 2016-11
    Erscheinungsland Pakistan
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 2490
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6532: Hefte anzeigen Standort:
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  4. Artikel: Pattern of MRI brain in neuro-psychiatric SLE. Effect of anti-phospholipid antibodies: A study at a tertiary care teaching hospital.

    Parvez, Khalid / Al-Arfaj, Abdul Rahman Saud / Hamdani, Muhammad Afzal / Naseeb, Faisal / Daif, Abdulkader / Hussain, Sajjad

    Pakistan journal of medical sciences

    2015  Band 31, Heft 5, Seite(n) 1182–1187

    Abstract: Objective: To compare the neuro-radiologic findings in Systemic lupus erythematosus (SLE) patients with and without antiphospholipid antibodies (aPL) in different neuro-psychiatric manifestations.: Methods: This cross-sectional comparative study was ... ...

    Abstract Objective: To compare the neuro-radiologic findings in Systemic lupus erythematosus (SLE) patients with and without antiphospholipid antibodies (aPL) in different neuro-psychiatric manifestations.
    Methods: This cross-sectional comparative study was carried out at King Khalid University Hospital, a tertiary care teaching hospital, Riyadh, Saudi Arabia from June 2012 to January 2015. Ninety seven SLE patients with neuro-psychiatric manifestations were included in the study and divided into two groups. Group I (50 patients) SLE with aPL and group II (47 patients) SLE without aPL. We compared Demographic features, clinical manifestations and magnetic resonance imaging (MRI) brain findings.
    Results: Demographic and clinical characteristics of two groups were similar. In Group-I, anticardiolipin antibodies (aCL) were most common (86%). In patients with headache, most of the patients in Group-I had white matter hyperintensities (WMHIs) (50% vs 27%) while most of the patients in Group-II had normal MRI brain (38% vs 73%). Similarly WMHIs were found more in Group-I patients with seizures (60% vs 21%), while ischemia/infarction, atrophy and normal MRI were found in Group-II. MRI brain in patients with neurological deficit and psychiatric disorder were not much different in both the groups.
    Conclusion: We found no statistically significant differences in frequencies of MRI brain abnormalities in SLE patients with and without aPL antibodies. Each of the three aPL may have a variable effect on the brain.
    Sprache Englisch
    Erscheinungsdatum 2015-10-28
    Erscheinungsland Pakistan
    Dokumenttyp Journal Article
    ZDB-ID 2032827-8
    ISSN 1681-715X ; 1682-024X ; 1017-4699
    ISSN (online) 1681-715X
    ISSN 1682-024X ; 1017-4699
    DOI 10.12669/pjms.315.7975
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 3948: Hefte anzeigen Standort:
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  5. Artikel: Pulmonary manifestations of systemic lupus erythematosus patients with and without antiphospholipid syndrome.

    Hamdani, Muhammad Afzal / Saud Al-Arfaj, Abdul Rahman / Parvez, Khalid / Naseeb, Faisal / Ibrahim, Abdalla El Fateh / Cal, Joseph Hope

    Pakistan journal of medical sciences

    2015  Band 31, Heft 1, Seite(n) 70–75

    Abstract: Objective: To uncover the pulmonary manifestations of Systemic Lupus Erythematosus (SLE) patients alone and to compare findings with antiphospholipid syndrome (APS) associated with SLE.: Methods: This cross sectional comparative study was carried out ...

    Abstract Objective: To uncover the pulmonary manifestations of Systemic Lupus Erythematosus (SLE) patients alone and to compare findings with antiphospholipid syndrome (APS) associated with SLE.
    Methods: This cross sectional comparative study was carried out at King Khalid University Hospital (KKUH)/King Saud University (KSU), a tertiary care hospital, Riyadh, Kingdom of Saudi Arabia. From June 2012 to March 2014, 96 diagnosed SLE patients with respiratory symptoms were included in the study and divided into two groups. Group one included SLE without antiphospholipid syndrome (APS) and group two SLE with APS. We compared Demographic features, clinical manifestations and findings of chest X-Ray, Arterial Blood Gases, Pulmonary function tests, six minute walk test, ventilation perfusion scan, echocardiography and chest high resolution computed tomography.
    Results: Demographic and clinical characteristics of two groups were similar. Previous history of deep venous thrombosis (3% vs 27.6%, p=0.001), pulmonary embolism (3% vs34.5%, p<0.0001) and abortions (7.5% vs 27.6%, p=0.019) were significantly more in group two. Levels of Anticardiolipin antibody (0% vs 100%, p<0.0001) and lupus anticoagulant (1.5% vs 79.3%, p<0.0001) were also significantly higher in group two. Hypoxemia measured by pulse oximetry (43.3% vs 65.5% p=0.045, pulmonary Arterial Hypertension (15.5% vs 39.3% p=0.014)), and pulmonary embolism (3.4% vs 21.4% p=0.013) and ventilation perfusion mismatch on V/Q scan (1.5% vs 24.1% p=0.001) were more frequent in group two.
    Conclusion: Hypoxemia, pulmonary embolism and pulmonary arterial hypertension were significantly high in SLE patients with APS, requiring long term anticoagulation and treatment and close follow-up.
    Sprache Englisch
    Erscheinungsdatum 2015-04-07
    Erscheinungsland Pakistan
    Dokumenttyp Journal Article
    ZDB-ID 2032827-8
    ISSN 1681-715X ; 1682-024X ; 1017-4699
    ISSN (online) 1681-715X
    ISSN 1682-024X ; 1017-4699
    DOI 10.12669/pjms.311.6544
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 3948: Hefte anzeigen Standort:
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