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Article ; Online: Virtual Reality for the Management of Pain and Anxiety in Patients Undergoing Implantation of Pacemaker or Implantable Cardioverter Defibrillator: A Randomized Study.

Squara, Fabien / Bateau, Jules / Scarlatti, Didier / Bun, Sok-Sithikun / Moceri, Pamela / Ferrari, Emile

2024 Volume 48, Issue 1, Page(s) 28

Abstract: Background: The Virtual Reality Headset (VRH) is a device aiming at improving patient's comfort by reducing pain and anxiety during medical interventions. Its interest during cardiac implantable electronic devices (CIED) implant procedures has not been ... ...

Abstract	Background: The Virtual Reality Headset (VRH) is a device aiming at improving patient's comfort by reducing pain and anxiety during medical interventions. Its interest during cardiac implantable electronic devices (CIED) implant procedures has not been studied. Methods: We randomized consecutive patients admitted for pacemaker or Implantable Cardioverter Defibrillator (ICD) at our center to either standard analgesia care (STD-Group), or to VRH (VRH-Group). Patients in the STD-Group received intra-venous paracetamol (1 g) 60 min before the procedure, and local anesthesia was performed with lidocaine. For patients of the VRH-Group, VRH was used on top of standard care. We monitored patients' pain and anxiety using numeric rating scales (from 0 to 10) at the time of sub-cutaneous pocket creation, and during deep axillary vein puncture. Patient comfort during the procedure was assessed using a detailed questionnaire. Morphine consumption was also assessed. Results: We randomized 61 patients to STD-Group (n = 31) or VRH-Group (n = 30). Pain and anxiety were lower in the VRH-Group during deep venous puncture (3.0 ± 2.0 vs. 4.8 ± 2.2, p = 0.002 and 2.4 ± 2.2 vs. 4.1 ± 2.4, p = 0.006) but not during pocket creation (p = 0.58 and p = 0.5). Morphine consumption was lower in the VRH-Group (1.6 ± 0.7 vs. 2.1 ± 1.1 mg; p = 0.041). Patients' overall comfort during procedure was similar in both groups. Conclusion: VRH use improved pain and anxiety control during deep venous puncture compared to standard analgesia care, and allowed morphine consumption reduction. However, pain and anxiety were similar at the time of sub-cutaneous pocket creation.
MeSH term(s)	Humans ; Defibrillators, Implantable ; Anxiety/prevention & control ; Pacemaker, Artificial ; Pain ; Morphine Derivatives
Chemical Substances	Morphine Derivatives
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	423488-1
ISSN	1573-689X ; 0148-5598
ISSN (online)	1573-689X
ISSN	0148-5598
DOI	10.1007/s10916-024-02039-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: CLOSE-Guided Pulmonary Vein Isolation to Treat Persistent Atrial Fibrillation: 1-Year Outcome.

Taghji, Philippe / Deharo, Jean-Claude / Amraoui, Sana / Bun, Sok-Sithikun

Journal of clinical medicine

2023 Volume 12, Issue 14

Abstract: Background: CLOSE-guided pulmonary vein isolation (PVI) is based on contiguous and optimized (Ablation Index-guided) radiofrequency lesions. The efficacy of CLOSE-guided PVI in persistent atrial fibrillation (AF) treatment has been poorly evaluated.: ... ...

Abstract	Background: CLOSE-guided pulmonary vein isolation (PVI) is based on contiguous and optimized (Ablation Index-guided) radiofrequency lesions. The efficacy of CLOSE-guided PVI in persistent atrial fibrillation (AF) treatment has been poorly evaluated. Methods: In two centers, 50 patients eligible for persistent AF ablation underwent CLOSE-guided PVI (Ablation Index ≥ 450 at the anterior wall, ≥300 at posterior wall, intertag distance ≤ 6 mm). If PVI failed to restore sinus rhythm (SR), electrical cardioversion (ECV) was performed. Atrial substrate modification (ASM) was performed only if PVI and ECV failed to restore SR. Recurrence was defined as any recorded episode of AF, atrial tachycardia (AT) or atrial flutter (AFL) > 30 s on Holter electrocardiographs at 3, 6 and 12 months. Results: From the 50 patients (64 ± 10 years, 14% long-standing persistent AF), SR was restored by ECV in 34 patients (68%) 56 ± 38 days prior to ablation. On the day of ablation, 42 patients (84%) were on class I-III anti-arrhythmic drug therapy (ADT) and the rhythm was AF in 23/50 patients. PVI was achieved in all patients; after PVI, ECV was required in 21 patients and ASM in 1 patient. The mean procedure time, radiofrequency time and fluoroscopy time were 141 ± 33 min, 23 ± 7 min and 7 ± 6 min, respectively. At 12 months, single-procedure freedom from AF/AT/AFL was 80%, with 19 patients (38%) receiving class I-III ADT. Conclusions: In a population of patients with persistent AF monitored with intermittent cardiac rhythm recordings, CLOSE-guided PVI resulted in high single-procedure arrhythmia-free survival at 1 year. Future large-scale studies involving continuous cardiac monitoring are necessary.
Language	English
Publishing date	2023-07-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12144698
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Ultrasound versus fluoroscopy-guided axillary vein access for cardiac device implantation.

Bun, Sok-Sithikun / Taghji, Philippe / Squara, Fabien / Massoure, Pierre-Laurent / Deharo, Jean-Claude / Ferrari, Emile

Revista espanola de cardiologia (English ed.)

2023 Volume 76, Issue 8, Page(s) 659–660

MeSH term(s)	Humans ; Axillary Vein/diagnostic imaging ; Axillary Vein/surgery ; Defibrillators, Implantable ; Pacemaker, Artificial ; Ultrasonography ; Fluoroscopy ; Ultrasonography, Interventional ; Prosthesis Implantation
Language	Spanish
Publishing date	2023-02-24
Publishing country	Spain
Document type	Case Reports
ZDB-ID	2592481-3
ISSN	1885-5857 ; 1885-5857
ISSN (online)	1885-5857
ISSN	1885-5857
DOI	10.1016/j.rec.2023.02.005
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Atrial fibrillation ablation in a single atrium with inferior vena cava interruption.

Bun, Sok-Sithikun / Squara, Fabien / Scarlatti, Didier / Moceri, Pamela / Ferrari, Emile

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

2023 Volume 28, Issue 4, Page(s) e13057

Abstract: Common atrium (CA), also called three-chambered heart, is one of the rare congenital anomalies, defined by a complete absence of the atrial septum, eventually associated with malformation of the atrioventricular (AV) valves. We report the case of a 57- ... ...

Abstract	Common atrium (CA), also called three-chambered heart, is one of the rare congenital anomalies, defined by a complete absence of the atrial septum, eventually associated with malformation of the atrioventricular (AV) valves. We report the case of a 57-year-old woman with CA complicated with Eisenmenger syndrome and inferior vena cava interruption, who suffered from symptomatic persistent atrial fibrillation (AF). She underwent an initial successful pulmonary vein isolation procedure. A repeat procedure for perivalvular atrial flutter was complicated with inadvertent complete AV block, due to unusual AV node location in this challenging anatomy.
MeSH term(s)	Female ; Humans ; Middle Aged ; Atrial Fibrillation/complications ; Atrial Fibrillation/surgery ; Vena Cava, Inferior/diagnostic imaging ; Vena Cava, Inferior/surgery ; Vena Cava, Inferior/abnormalities ; Treatment Outcome ; Electrocardiography ; Heart Defects, Congenital/surgery ; Atrioventricular Node ; Heart Septal Defects ; Catheter Ablation/methods
Language	English
Publishing date	2023-03-31
Publishing country	United States
Document type	Case Reports
ZDB-ID	1325530-7
ISSN	1542-474X ; 1082-720X
ISSN (online)	1542-474X
ISSN	1082-720X
DOI	10.1111/anec.13057
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 4953: Show issues

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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Ethanol infusion in left atrial appendage vein for treating refractory left atrial appendage tachycardia.

Squara, Fabien / Scarlatti, Didier / Baudouy, Delphine / Bun, Sok-Sithikun / Moceri, Pamela / Ferrari, Emile

Journal of cardiovascular electrophysiology

2023 Volume 34, Issue 7, Page(s) 1577–1581

Abstract: Introduction: We describe an unusual case of atrial tachycardia (AT) emanating from the left atrial appendage body (LAA), successfully treated by chemical ablation.: Methods: A 66-year-old patient with cardiac amyloidosis and history of persistent ... ...

Abstract	Introduction: We describe an unusual case of atrial tachycardia (AT) emanating from the left atrial appendage body (LAA), successfully treated by chemical ablation. Methods: A 66-year-old patient with cardiac amyloidosis and history of persistent atrial fibrillation ablation presented poorly tolerated AT with 1:1 atrioventricular nodal conduction at 135/min, despite amiodarone therapy. Three-dimensional mapping suggested a reentrant AT from the anterior aspect of the left LAA. Results: The tachycardia could not be terminated with radiofrequency ablation. The LAA vein was then selectively catheterized and infused with Ethanol, resulting in immediate termination of tachycardia, without LAA isolation. No recurrence occurred at 12 months. Conclusion: Atrial tachycardias emanating from the LAA that are resistant to radiofrequency ablation may respond to chemical ablation of the LAA vein.
MeSH term(s)	Humans ; Aged ; Atrial Appendage/diagnostic imaging ; Atrial Appendage/surgery ; Treatment Outcome ; Tachycardia ; Atrial Fibrillation/complications ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/drug therapy ; Tachycardia, Supraventricular ; Catheter Ablation/adverse effects ; Catheter Ablation/methods
Language	English
Publishing date	2023-06-09
Publishing country	United States
Document type	Case Reports
ZDB-ID	1025989-2
ISSN	1540-8167 ; 1045-3873
ISSN (online)	1540-8167
ISSN	1045-3873
DOI	10.1111/jce.15966
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 2863: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article: Fibrillatory Wave Amplitude Evolution during Persistent Atrial Fibrillation Ablation: Implications for Atrial Substrate and Fibrillation Complexity Assessment.

Squara, Fabien / Scarlatti, Didier / Bun, Sok-Sithikun / Moceri, Pamela / Ferrari, Emile / Meste, Olivier / Zarzoso, Vicente

Journal of clinical medicine

2022 Volume 11, Issue 15

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2022-08-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11154519
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Prevalence and Clinical Characteristics of Patients with Torsades de Pointes Complicating Acquired Atrioventricular Block

Sok-Sithikun Bun / Nathan Heme / Florian Asarisi / Fabien Squara / Didier Scarlatti / Pamela Moceri / Emile Ferrari

Journal of Clinical Medicine, Vol 12, Iss 1067, p

2023 Volume 1067

Abstract: Background: Female gender, degree of QT prolongation, and genetic susceptibility are known risk factors for developing torsades de pointes (TdP) during high-grade atrioventricular block (HG-AVB). Our objective was to analyze the prevalence and clinical ... ...

Abstract	Background: Female gender, degree of QT prolongation, and genetic susceptibility are known risk factors for developing torsades de pointes (TdP) during high-grade atrioventricular block (HG-AVB). Our objective was to analyze the prevalence and clinical characteristics of patients presenting with TdP and AVB (TdP [+]) in comparison with non-TdP patients with AVB (TdP [−]). Methods: All the ECGs from patients prospectively admitted for AVB (2 to 1, HG, and complete) at the University Hospital of Nice were analyzed. Automated corrected QT (QTc), manual measurements of QT and JT intervals, and Tpeak-to-end were performed at the time of the most severe bradycardia. Results: From September 2020 to November 2021, 100 patients were admitted for HG-AVB. Among them, 17 patients with TdP were identified (8 men; 81 ± 10 years). No differences could be identified concerning automated QTc, manual QTc (Bazett correction), baseline QRS width, or mean left ventricular ejection fraction between the two groups. Potassium serum level on admission and mean number of QT-prolonging drugs per patient were not significantly different between the two groups, respectively: 4.34 ± 0.5 mmol/L in TdP [+] versus 4.52 ± 0.6 mmol/L ( p = 0.33); and 0.6 ± 0.7 in TdP [+] versus 0.3 ± 0.5 ( p = 0.15). In contrast, manual QTc FR (Fridericia correction), JT (Fridericia correction), Tpeak-to-end, and Tpe/QT ratio were significantly increased in the TdP [+] group, respectively: 486 ± 70 ms versus 456 ± 53 ms ( p = 0.04); 433 ± 98 ms versus 381 ± 80 ms ( p = 0.02); 153 ± 57 ms versus 110 ± 40 ms ( p < 0.001); and 0.27 ± 0.08 versus 0.22 ± 0.06 ( p < 0.001). Conclusions: The incidence of TdP complicating acquired AVB was 17%. Longer QTc FR , JT, and Tpeak-to-end were significantly increased in the case of TdP but also in the presence of permanent AVB during the hospitalization.
Keywords	atrioventricular block ; torsades de pointes ; QT interval ; Medicine ; R
Subject code	610
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Prevalence and Clinical Characteristics of Patients with Torsades de Pointes Complicating Acquired Atrioventricular Block.

Bun, Sok-Sithikun / Heme, Nathan / Asarisi, Florian / Squara, Fabien / Scarlatti, Didier / Moceri, Pamela / Ferrari, Emile

Journal of clinical medicine

2023 Volume 12, Issue 3

Abstract	Background: Female gender, degree of QT prolongation, and genetic susceptibility are known risk factors for developing torsades de pointes (TdP) during high-grade atrioventricular block (HG-AVB). Our objective was to analyze the prevalence and clinical characteristics of patients presenting with TdP and AVB (TdP [+]) in comparison with non-TdP patients with AVB (TdP [-]). Methods: All the ECGs from patients prospectively admitted for AVB (2 to 1, HG, and complete) at the University Hospital of Nice were analyzed. Automated corrected QT (QTc), manual measurements of QT and JT intervals, and Tpeak-to-end were performed at the time of the most severe bradycardia. Results: From September 2020 to November 2021, 100 patients were admitted for HG-AVB. Among them, 17 patients with TdP were identified (8 men; 81 ± 10 years). No differences could be identified concerning automated QTc, manual QTc (Bazett correction), baseline QRS width, or mean left ventricular ejection fraction between the two groups. Potassium serum level on admission and mean number of QT-prolonging drugs per patient were not significantly different between the two groups, respectively: 4.34 ± 0.5 mmol/L in TdP [+] versus 4.52 ± 0.6 mmol/L ( Conclusions: The incidence of TdP complicating acquired AVB was 17%. Longer QTc
Language	English
Publishing date	2023-01-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12031067
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: High-density mapping of the average complex interval helps localizing atrial fibrillation drivers and predicts catheter ablation outcomes.

Squara, Fabien / Scarlatti, Didier / Bun, Sok-Sithikun / Moceri, Pamela / Ferrari, Emile / Meste, Olivier / Zarzoso, Vicente

Frontiers in cardiovascular medicine

2023 Volume 10, Page(s) 1145894

Abstract: Background: Persistent Atrial Fibrillation (PersAF) electrogram-based ablation is complex, and appropriate identification of atrial substrate is critical. Little is known regarding the value of the Average Complex Interval (ACI) feature for PersAF ... ...

Abstract	Background: Persistent Atrial Fibrillation (PersAF) electrogram-based ablation is complex, and appropriate identification of atrial substrate is critical. Little is known regarding the value of the Average Complex Interval (ACI) feature for PersAF ablation. Objective: Using the evolution of AF complexity by sequentially computing AF dominant frequency (DF) along the ablation procedure, we sought to evaluate the value of ACI for discriminating active drivers (AD) from bystander zones (BZ), for predicting AF termination during ablation, and for predicting AF recurrence during follow-up. Methods: We included PersAF patients undergoing radiofrequency catheter ablation by pulmonary vein isolation and ablation of atrial substrate identified by Spatiotemporal Dispersion or Complex Fractionated Atrial Electrograms (>70% of recording). Operators were blinded to ACI measurement which was sought for each documented atrial substrate area. AF DF was measured by Independent Component Analysis on 1-minute 12-lead ECGs at baseline and after ablation of each atrial zone. AD were differentiated from BZ either by a significant decrease in DF (>10%), or by AF termination. Arrhythmia recurrence was monitored during follow-up. Results: We analyzed 159 atrial areas (129 treated by radiofrequency during AF) in 29 patients. ACI was shorter in AD than BZ (76.4 ± 13.6 vs. 86.6 ± 20.3 ms; Conclusion: ACI helps in identifying AF drivers, and is correlated with AF termination and AF recurrence during follow-up. It can help in establishing an ablation plan, by prioritizing ablation from the shortest to the longest ACI zone.
Language	English
Publishing date	2023-08-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2023.1145894
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Corrigendum.

Bun, Sok-Sithikun / Latcu, Decebal Gabriel / Wedn, Ahmed Mostfa / Saoudi, Nadir

HeartRhythm case reports

2019 Volume 5, Issue 11, Page(s) 560

Abstract: This corrects the article DOI: 10.1016/j.hrcr.2018.07.002.]. ...

Abstract	[This corrects the article DOI: 10.1016/j.hrcr.2018.07.002.].
Language	English
Publishing date	2019-10-21
Publishing country	United States
Document type	Published Erratum
ZDB-ID	2834871-0
ISSN	2214-0271
ISSN	2214-0271
DOI	10.1016/j.hrcr.2019.10.002
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