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  1. Article ; Online: Post-migration HIV acquisition: A systematic review and meta-analysis.

    Mann, Simran / Mougammadou, Zeenathnisa / Wohlfahrt, Jan / Elmahdi, Rahma

    Epidemiology and infection

    2024  Volume 152, Page(s) e49

    Abstract: Migrants in Europe face a disproportionate burden of HIV infection; however, it remains unclear if this can be prevented through public health interventions in host countries. We undertake a systematic review and meta-analysis to estimate post-migration ... ...

    Abstract Migrants in Europe face a disproportionate burden of HIV infection; however, it remains unclear if this can be prevented through public health interventions in host countries. We undertake a systematic review and meta-analysis to estimate post-migration HIV acquisition (PMHA) as a proportion of all HIV cases in European migrants. MEDLINE, EMBASE, Global Health, HMIC, and Cochrane Library were searched with terms capturing 'HIV', 'migration', and 'Europe'. Data relating to the proportion of HIV acquired following migration were extracted and random-effects model (REM) meta-analysis was undertaken to calculate a pooled estimate for the proportion of PMHA in European countries. Subgroup meta-analysis was undertaken for PMHA by migrant demographic characteristics and host country. Fifteen articles were included for systematic review following retrieval and screening of 2,320 articles. A total of 47,182 migrants in 11 European countries were included in REM meta-analysis, showing an overall PMHA proportion of 0.30 (95% CI: 0.23-0.38). Subgroup analysis showed no significant difference in PMHA between host country and migrant demographic characteristics. This work illustrates that migrants continue to be at high risk of HIV acquisition in Europe. This indicates the need for targeted screening and HIV prevention interventions, ensuring resources are appropriately directed to combat the spread of HIV.
    MeSH term(s) Humans ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; HIV ; Europe/epidemiology ; Communicable Disease Control ; Transients and Migrants
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S0950268824000372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Qualitative fit testing.

    Mann, Simran / Afnan, Michael

    Clinical medicine (London, England)

    2020  Volume 20, Issue 6, Page(s) e278–e279

    MeSH term(s) Humans ; Occupational Exposure
    Language English
    Publishing date 2020-11-13
    Publishing country England
    Document type Letter
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.Let.20.6.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Gender bias in medical education: Stop treating it as an inevitability.

    Mann, Simran / Ariyanayagam, David

    Medical education

    2020  Volume 54, Issue 9, Page(s) 863

    MeSH term(s) Education, Medical ; Female ; Humans ; Learning ; Male ; Qualitative Research ; Sexism ; Students, Medical
    Language English
    Publishing date 2020-05-27
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 195274-2
    ISSN 1365-2923 ; 0308-0110
    ISSN (online) 1365-2923
    ISSN 0308-0110
    DOI 10.1111/medu.14186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Potential treatments of COVID-19: Drug repurposing and therapeutic interventions.

    Raghav, Pawan Kumar / Mann, Zoya / Ahluwalia, Simran Kaur / Rajalingam, Raja

    Journal of pharmacological sciences

    2023  Volume 152, Issue 1, Page(s) 1–21

    Abstract: The coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection is caused when Spike-protein (S-protein) present on the surface of SARS-CoV-2 interacts with human cell surface receptor, ... ...

    Abstract The coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection is caused when Spike-protein (S-protein) present on the surface of SARS-CoV-2 interacts with human cell surface receptor, Angiotensin-converting enzyme 2 (ACE2). This binding facilitates SARS-CoV-2 genome entry into the human cells, which in turn causes infection. Since the beginning of the pandemic, many different therapies have been developed to combat COVID-19, including treatment and prevention. This review is focused on the currently adapted and certain other potential therapies for COVID-19 treatment, which include drug repurposing, vaccines and drug-free therapies. The efficacy of various treatment options is constantly being tested through clinical trials and in vivo studies before they are made medically available to the public.
    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2/metabolism ; Drug Repositioning ; COVID-19 Drug Treatment ; Peptidyl-Dipeptidase A/genetics ; Peptidyl-Dipeptidase A/metabolism ; Protein Binding
    Chemical Substances Peptidyl-Dipeptidase A (EC 3.4.15.1)
    Language English
    Publishing date 2023-02-15
    Publishing country Japan
    Document type Review ; Journal Article
    ZDB-ID 2104264-0
    ISSN 1347-8648 ; 1347-8613
    ISSN (online) 1347-8648
    ISSN 1347-8613
    DOI 10.1016/j.jphs.2023.02.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Risk of Cervical Cancer in Inflammatory Bowel Disease: A Meta-Analysis of Population-Based Studies.

    Mann, Simran / Jess, Tine / Allin, Kristine / Elmahdi, Rahma

    Clinical and translational gastroenterology

    2022  Volume 13, Issue 7, Page(s) e00513

    Abstract: Introduction: There is increased risk of several malignancies in inflammatory bowel disease (IBD). However, evidence regarding risk of cervical cancer in IBD is conflicting. We aimed to investigate the risk of cervical cancer in IBD by undertaking a ... ...

    Abstract Introduction: There is increased risk of several malignancies in inflammatory bowel disease (IBD). However, evidence regarding risk of cervical cancer in IBD is conflicting. We aimed to investigate the risk of cervical cancer in IBD by undertaking a systematic review and meta-analysis of unselected, population-based studies.
    Methods: MEDLINE, EMBASE, and Cochrane Library were searched using Medical Subject Heading terms, and 2 reviewers independently screened results. Pooled hazard ratios (HRs) were calculated using random effects model meta-analysis for risk of cervical cancer in IBD. Subgroup meta-analysis was undertaken to assess risk of cervical cancer by IBD subtype (Crohn's disease and ulcerative colitis), treatment exposure, and grade of lesion.
    Results: We screened 1,393 articles to identify 5 population-based studies, including 74,310 patients with IBD and 2,029,087 reference patients, across 5 different countries. Pooled random effects model meta-analysis of these studies did not show statistically significant increased risk for cervical cancer in IBD compared with reference populations (HR: 1.24; 95% confidence interval [CI]: 0.94-1.63). Meta-analysis by grade of lesion showed increased risk of low-grade cervical lesions (HR: 1.15; 95% CI: 1.04-1.28). Meta-analysis by disease subtype indicated no statistically significant increased risk in Crohn's disease (HR: 1.36; 95% CI: 0.83-2.23) or ulcerative colitis (HR: 0.95; 95% CI: 0.72-1.25) or in patients treated with antitumor necrosis factor (HR: 1.19; 95% CI: 0.64-2.21) or thiopurines (HR: 0.96; 95% CI: 0.60-1.50).
    Discussion: This meta-analysis of high-quality, unselected population-based studies shows no statistically significant increased risk of cervical cancer in patients with IBD. There is, however, increased risk of low-grade cervical lesions compared with the general population.
    MeSH term(s) Chronic Disease ; Colitis, Ulcerative/complications ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/epidemiology ; Crohn Disease/complications ; Crohn Disease/drug therapy ; Crohn Disease/epidemiology ; Female ; Humans ; Inflammatory Bowel Diseases/complications ; Inflammatory Bowel Diseases/drug therapy ; Inflammatory Bowel Diseases/epidemiology ; Uterine Cervical Neoplasms/epidemiology
    Language English
    Publishing date 2022-06-15
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2581516-7
    ISSN 2155-384X ; 2155-384X
    ISSN (online) 2155-384X
    ISSN 2155-384X
    DOI 10.14309/ctg.0000000000000513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Simulations and Virtual Learning Supporting Clinical Education During the COVID 19 Pandemic [Letter].

    Novintan, Shonnelly / Mann, Simran / Hazemi-Jebelli, Yasmin

    Advances in medical education and practice

    2020  Volume 11, Page(s) 649–650

    Keywords covid19
    Language English
    Publishing date 2020-09-29
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2578539-4
    ISSN 1179-7258
    ISSN 1179-7258
    DOI 10.2147/AMEP.S276699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Book ; Online: Simulations and Virtual Learning Supporting Clinical Education During the COVID 19 Pandemic [Letter]

    Novintan, Shonnelly / Mann, Simran / Hazemi-Jebelli, Yasmin

    2020  

    Abstract: Shonnelly Novintan, Simran Mann, Yasmin Hazemi-Jebelli Faculty of Medicine, Department of Medicine ...

    Abstract Shonnelly Novintan, Simran Mann, Yasmin Hazemi-Jebelli Faculty of Medicine, Department of Medicine, Imperial College School of Medicine, London, UKCorrespondence: Shonnelly Novintan Kensington, Faculty of Medicine, Imperial College LondonSir Alexander Fleming Building, Imperial College Road London SW7 2AZ, UKTel +44 7738362140Email sn2315@ic.ac.uk We read with great interest the article by Tabatabai regarding virtual learning supporting clinical education and examination during the COVID-19 pandemic.1 As final year medical students, we have experienced months of remote teaching followed by online exams. It is interesting that we share same similar benefits of virtual learning in the UK. However, we believe that virtual platforms fail to meet the practical needs of students and could leave significant gaps in our clinical competency. View the original paper by Tabatabai
    Keywords Advances in Medical Education and Practice ; covid19
    Language English
    Publishing date 2020-09-29
    Publisher Dove Press
    Publishing country us
    Document type Article ; Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Simulations and Virtual Learning Supporting Clinical Education During the COVID 19 Pandemic [Letter]

    Novintan, Shonnelly / Mann, Simran / Hazemi-Jebelli, Yasmin

    Advances in Medical Education and Practice

    2020  Volume Volume 11, Page(s) 649–650

    Keywords covid19
    Language English
    Publisher Informa UK Limited
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 2578539-4
    ISSN 1179-7258
    ISSN 1179-7258
    DOI 10.2147/amep.s276699
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Medical Students' Corner: Lessons From COVID-19 in Equity, Adaptability, and Community for the Future of Medical Education.

    Mann, Simran / Novintan, Shonnelly / Hazemi-Jebelli, Yasmin / Faehndrich, Daniel

    JMIR medical education

    2020  Volume 6, Issue 2, Page(s) e23604

    Abstract: As UK medical students, we recently completed 3 months of remote learning due to the COVID-19 pandemic, before taking online end-of-the-year exams. We are now entering our final year of medical school. Based on our experiences and our understanding of ... ...

    Abstract As UK medical students, we recently completed 3 months of remote learning due to the COVID-19 pandemic, before taking online end-of-the-year exams. We are now entering our final year of medical school. Based on our experiences and our understanding of others' experiences, we believe that three key lessons have been universal for medical students around the world. The lessons learned throughout this process address the need for a fair system for medical students, the importance of adaptability in all aspects of medical education, and the value of a strong medical school community. These lessons can be applied in the years to come to improve medical education as we know it.
    Keywords covid19
    Language English
    Publishing date 2020-10-09
    Publishing country Canada
    Document type Journal Article
    ISSN 2369-3762
    ISSN 2369-3762
    DOI 10.2196/23604
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Medical Students' Corner: Lessons From COVID-19 in Equity, Adaptability, and Community for the Future of Medical Education

    Mann, Simran / Novintan, Shonnelly / Hazemi-Jebelli, Yasmin / Faehndrich, Daniel

    JMIR Med Educ

    Abstract: As UK medical students, we recently completed 3 months of remote learning due to the COVID-19 pandemic, before taking online end-of-the-year exams. We are now entering our final year of medical school. Based on our experiences and our understanding of ... ...

    Abstract As UK medical students, we recently completed 3 months of remote learning due to the COVID-19 pandemic, before taking online end-of-the-year exams. We are now entering our final year of medical school. Based on our experiences and our understanding of others' experiences, we believe that three key lessons have been universal for medical students around the world. The lessons learned throughout this process address the need for a fair system for medical students, the importance of adaptability in all aspects of medical education, and the value of a strong medical school community. These lessons can be applied in the years to come to improve medical education as we know it.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #862865
    Database COVID19

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