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  1. Article ; Online: Survey of women's perceptions of information provided in the prevention or treatment of iron deficiency anaemia in an Australian tertiary obstetric hospital.

    Vosnacos, Emma / Pinchon, Deborah J

    Women and birth : journal of the Australian College of Midwives

    2015  Volume 28, Issue 2, Page(s) 166–172

    Abstract: Background: There is limited literature to understand the perceptions of Australian women regarding the information provided by healthcare professionals relating to the prevention and treatment of iron deficiency anaemia in pregnancy.: Aim: To ... ...

    Abstract Background: There is limited literature to understand the perceptions of Australian women regarding the information provided by healthcare professionals relating to the prevention and treatment of iron deficiency anaemia in pregnancy.
    Aim: To establish an insight into the key themes and trends within a tertiary obstetric hospital related to the provision of dietary advice and use of iron supplements in pregnancy.
    Methods: A prospective patient survey of pregnant women and women up to 4 weeks postnatal attending hospital.
    Findings: Of the 110 women who participated, 73.6% were provided with information on iron rich foods and 67% made dietary changes. Eighty percent of women were advised to take oral iron and 65.5% of women were taking it at the time of the survey. In women who had independently ceased oral iron, 41.7% failed to inform their healthcare professional. In the women who did inform their healthcare professional 89.5% received advice to help overcome the reason that led to cessation. The main causes included forgetfulness and side effects. Women were less likely to require intravenous iron if oral iron was commenced early.
    Conclusions: Compliance with recommended oral iron is variable within a population of pregnant women. Women are provided with information on a range of issues relating to the prevention and treatment of iron deficiency anaemia; yet there is a disparity between the information provided and the resulting action. Further research should focus on targeted measures to improve understanding and compliance with treatment from the both women's and health professionals perspective.
    MeSH term(s) Adult ; Anemia, Iron-Deficiency/prevention & control ; Anemia, Iron-Deficiency/therapy ; Australia ; Dietary Supplements ; Female ; Folic Acid/administration & dosage ; Health Knowledge, Attitudes, Practice ; Humans ; Iron, Dietary/administration & dosage ; Patient Compliance ; Patient Education as Topic ; Patient Satisfaction ; Perception ; Postpartum Period ; Pregnancy ; Pregnant Women/psychology ; Prospective Studies ; Surveys and Questionnaires ; Tertiary Care Centers
    Chemical Substances Iron, Dietary ; Folic Acid (935E97BOY8)
    Language English
    Publishing date 2015-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2235085-8
    ISSN 1878-1799 ; 1871-5192
    ISSN (online) 1878-1799
    ISSN 1871-5192
    DOI 10.1016/j.wombi.2014.11.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The XP-Endo Finisher for the removal of calcium hydroxide paste from root canals and from the apical third.

    Hamdan, Rami / Michetti, Jérôme / Pinchon, Déborah / Diemer, Franck / Georgelin-Gurgel, Marie

    Journal of clinical and experimental dentistry

    2017  Volume 9, Issue 7, Page(s) e855–e860

    Abstract: Background: The aim was to compare the efficacy of the passive ultrasonic irrigation PUI and the Xp-endo Finisher (FKG-Dentaire, La-Chaux-de-Fonds, Switzerland) in removing the calcium hydroxide paste from root canals and from the apical third.: ... ...

    Abstract Background: The aim was to compare the efficacy of the passive ultrasonic irrigation PUI and the Xp-endo Finisher (FKG-Dentaire, La-Chaux-de-Fonds, Switzerland) in removing the calcium hydroxide paste from root canals and from the apical third.
    Material and methods: Sixty-eight root canals of single-rooted teeth were shaped using the BT-Race files (FKG-Dentaire, La-Chaux-de-Fonds, Switzerland). Ca(OH)2 was placed in all samples except for the negative control group (n=4). Remaining teeth were randomly divided into three groups: G1-Xp (n=30), G2-PUI (n=30) and the positive control group (n=4). Removal procedure consisted of three repeated one-minute-cycles. Samples were split longitudinally, photos of halves were taken at X6.4 magnification and were analyzed using the ImageJ-Software (The National Institutes of Health NIH, Bethesda, Maryland, USA) to calculate the percentage of surfaces with residual Ca(OH)2; the results were compared using the Wilcoxon-Mann Whitney test. Photos of the apical thirds were taken at X16 and X40 magnifications and were scored by two examiners from (0) to (4). Scores of the apical third were compared using the Fisher test.
    Results: The Xp-endo Finisher removed completely the Ca(OH)2 dressing from four teeth (13.33%) whereas the PUI in one tooth (3.33%). The mean values of the remaining Ca(OH)2 were (2.1%, 3.6%) respectively and the difference was not significant (
    Conclusions: The Xp-endo Finisher showed a superiority over the PUI in removing the Ca(OH)2 from the apical third after 3 minutes of activation.
    Language English
    Publishing date 2017-07-01
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2586647-3
    ISSN 1989-5488
    ISSN 1989-5488
    DOI 10.4317/jced.53962
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Does bleeding affect patient-reported outcome measures in patients with myelodysplasia or hematologic malignancies: a systematic review.

    Estcourt, Lise J / Pinchon, Deborah / Symington, Emily / Kelly, Anne M / Doree, Carolyn / Brunskill, Susan / Glidewell, Liz / Stanworth, Simon

    Transfusion

    2014  Volume 54, Issue 4, Page(s) 1166–1179

    Abstract: Background: Relatively minor bleeding (e.g., bruising and/or petechiae) may cause patient distress. This systematic review's objective was to assess whether bleeding affects health-related quality of life (HRQoL) or illness perceptions or ... ...

    Abstract Background: Relatively minor bleeding (e.g., bruising and/or petechiae) may cause patient distress. This systematic review's objective was to assess whether bleeding affects health-related quality of life (HRQoL) or illness perceptions or representations (IPs) in patients with hematologic malignancies or myelodysplasia (MDS).
    Study design and methods: We searched, in full, 12 electronic databases (including CENTRAL, MEDLINE, and EMBASE) up to January 7, 2013, for eligible randomized controlled trials (RCTs), prospective cohort studies, and cross-sectional studies.
    Results: A total of 6247 studies were initially identified; 5945 studies were excluded on the basis of the abstract. A total of 302 full-text articles were evaluated independently by two reviewers; of these, six studies within seven citations were eligible for inclusion. Two studies are still in progress, four studies within five citations were included in this review (one RCT, one prospective observational study, one interview study, and one Web-based survey). None of the included studies were designed to assess the impact bleeding had on HRQoL or IPs. The Web-based survey and observational study used two new patient-reported outcome scales which specifically assessed patient distress or concern due to bleeding. The majority of patients within these two studies either did not experience bleeding or did not have severe thrombocytopenia.
    Conclusion: There is insufficient evidence to demonstrate whether bleeding is a significant clinical problem that affects patients' HRQoL or IPs in either patients with MDS or patients with hematologic malignancies. Rigorously designed studies to assess the scale of this problem in both of these groups of patients are required.
    MeSH term(s) Cohort Studies ; Cross-Sectional Studies ; Hematologic Neoplasms/complications ; Hematologic Neoplasms/diagnosis ; Hematologic Neoplasms/epidemiology ; Hemorrhage/complications ; Hemorrhage/diagnosis ; Hemorrhage/epidemiology ; Humans ; Myelodysplastic Syndromes/complications ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/epidemiology ; Prognosis ; Randomized Controlled Trials as Topic/statistics & numerical data ; Self Concept ; Self Report
    Language English
    Publishing date 2014-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 208417-x
    ISSN 1537-2995 ; 0041-1132
    ISSN (online) 1537-2995
    ISSN 0041-1132
    DOI 10.1111/trf.12441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Quality of life and use of red cell transfusion in patients with myelodysplastic syndromes. A systematic review.

    Pinchon, Deborah J / Stanworth, Simon J / Dorée, Carolyn / Brunskill, Susan / Norfolk, Derek R

    American journal of hematology

    2009  Volume 84, Issue 10, Page(s) 671–677

    Abstract: The main treatment for many patients with Myelodysplastic Syndromes (MDS) remains red cell transfusion to attenuate the symptoms of chronic anemia. Fatigue can reduce a patient's health related quality of life (HRQoL), but there is little understanding ... ...

    Abstract The main treatment for many patients with Myelodysplastic Syndromes (MDS) remains red cell transfusion to attenuate the symptoms of chronic anemia. Fatigue can reduce a patient's health related quality of life (HRQoL), but there is little understanding of the optimal use of transfusions to improve this. A systematic review was performed to identify and appraise publications reporting the use of HRQoL instruments in patients with MDS. A total of 17 separate studies were identified that used 14 HRQoL instruments, but only one MDS disease specific HRQoL instrument (QOL-E) was reported. Two well established HRQoL instruments were most often used in MDS research (variants of the Functional Assessment of Cancer Therapy (FACT) and the European Organisation for Research and Treatment of Cancer Core Quality of Life Questionnaire (QLQ-C30)). Several common problems were identified in the published literature including a lack of power calculations to detect clinically relevant changes, small sample sizes and significant attrition rates for completion of HRQoL assessments, all of which limit the strength of any conclusions. There is no consensus on the optimal transfusion regimen to improve HRQoL in transfusion-dependent MDS. Future research into HRQoL within MDS is a pressing requirement. Studies should focus on the domains that are of most clinical importance to the patient as well as traditional quantitative changes of hemoglobin concentration.
    MeSH term(s) Erythrocyte Transfusion ; Humans ; Myelodysplastic Syndromes/psychology ; Myelodysplastic Syndromes/therapy ; Quality of Life
    Language English
    Publishing date 2009-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.21503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Guideline on the investigation and management of acute transfusion reactions. Prepared by the BCSH Blood Transfusion Task Force.

    Tinegate, Hazel / Birchall, Janet / Gray, Alexandra / Haggas, Richard / Massey, Edwin / Norfolk, Derek / Pinchon, Deborah / Sewell, Carrock / Wells, Angus / Allard, Shubha

    British journal of haematology

    2012  Volume 159, Issue 2, Page(s) 143–153

    Abstract: Although acute non-haemolytic febrile or allergic reactions (ATRs) are a common complication of transfusion and often result in little or no morbidity, prompt recognition and management are essential. The serious hazards of transfusion haemovigilance ... ...

    Abstract Although acute non-haemolytic febrile or allergic reactions (ATRs) are a common complication of transfusion and often result in little or no morbidity, prompt recognition and management are essential. The serious hazards of transfusion haemovigilance organisation (SHOT) receives 30-40 reports of anaphylactic reactions each year. Other serious complications of transfusion, such as acute haemolysis, bacterial contamination, transfusion-related acute lung injury (TRALI) or transfusion-associated circulatory overload (TACO) may present with similar clinical features to ATR. This guideline describes the approach to a patient developing adverse symptoms and signs related to transfusion, including initial recognition, establishing a likely cause, treatment, investigations, planning future transfusion and reporting within the hospital and to haemovigilance organisations. Key recommendations are that adrenaline should be used as first line treatment of anaphylaxis, and that transfusions should only be carried out where patients can be directly observed and where staff are trained in manging complications of transfusion, particularly anaphylaxis. Management of ATRs is not dependent on classification but should be guided by symptoms and signs. Patients who have experienced an anaphylactic reaction should be discussed with an allergist or immunologist, in keeping with UK resuscitation council guidelines.
    MeSH term(s) Humans ; Acute Lung Injury/etiology ; Acute Lung Injury/therapy ; Anaphylaxis/etiology ; Anaphylaxis/therapy ; Bacterial Infections/etiology ; Bacterial Infections/therapy ; Blood Safety ; Blood-Borne Pathogens ; Hemolysis ; Transfusion Reaction
    Language English
    Publishing date 2012-08-29
    Publishing country England
    Document type Journal Article ; Practice Guideline
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.12017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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