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  1. Article ; Online: Advanced Cardiac Imaging in the Assessment of Aortic Stenosis.

    Grodecki, Kajetan / Warniello, Mateusz / Spiewak, Mateusz / Kwiecinski, Jacek

    Journal of cardiovascular development and disease

    2023  Volume 10, Issue 5

    Abstract: Aortic stenosis is the most common form of valve disease in the Western world and a major healthcare burden. Although echocardiography remains the central modality for the diagnosis and assessment of aortic stenosis, recently, advanced cardiac imaging ... ...

    Abstract Aortic stenosis is the most common form of valve disease in the Western world and a major healthcare burden. Although echocardiography remains the central modality for the diagnosis and assessment of aortic stenosis, recently, advanced cardiac imaging with cardiovascular magnetic resonance, computed tomography, and positron emission tomography have provided invaluable pathological insights that may guide the personalized management of the disease. In this review, we discuss applications of these novel non-invasive imaging modalities for establishing the diagnosis, monitoring disease progression, and eventually planning the invasive treatment of aortic stenosis.
    Language English
    Publishing date 2023-05-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd10050216
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  2. Article ; Online: Letter: Refining the prediction of side branch occlusion following percutaneous coronary intervention in bifurcation lesions.

    Grodecki, Kajetan / Opolski, Maksymilian P

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2020  Volume 16, Issue 6, Page(s) e525–e526

    MeSH term(s) Coronary Angiography ; Coronary Occlusion ; Humans ; Percutaneous Coronary Intervention ; Prospective Studies
    Language English
    Publishing date 2020-08-07
    Publishing country France
    Document type Letter ; Comment
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJ-D-19-01107L
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  3. Article: Impact of previous coronary artery revascularization on outcomes in patients undergoing transcatheter aortic valve implantation.

    Wilimski, Radosław / Huczek, Zenon / Krauz, Kamil / Rymuza, Bartosz / Mazurek, Maciej / Scisło, Piotr / Zbroński, Karol / Grodecki, Kajetan / Kochman, Janusz / Kuśmierczyk, Mariusz

    Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

    2023  Volume 19, Issue 3, Page(s) 243–250

    Abstract: Introduction: Coexistence of coronary artery disease (CAD) in patients with severe aortic stenosis (AS) referred for transcatheter aortic valve implantation (TAVI) raises questions regarding the safety and efficacy of TAVI in this subset of patients.: ...

    Abstract Introduction: Coexistence of coronary artery disease (CAD) in patients with severe aortic stenosis (AS) referred for transcatheter aortic valve implantation (TAVI) raises questions regarding the safety and efficacy of TAVI in this subset of patients.
    Aim: To evaluate the impact of previous coronary revascularization in terms of percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) on clinical outcomes after TAVI.
    Material and methods: A total of 507 consecutive patients who underwent TAVI were divided into: non-revascularization (NR), post-PCI and post-CABG groups. The endpoints were established according to VARC-2 definitions.
    Results: Patients with previous coronary revascularization (36.7% of the population) were younger, more often male and their EuroSCORE II risk evaluation was significantly higher (NR 7.9% vs. post-PCI 8.0% vs. post-CABG 20.5%,
    Conclusions: TAVI seems to be a safe and effective procedure for the treatment of severe AS in patients with previous coronary revascularization.
    Language English
    Publishing date 2023-09-27
    Publishing country Poland
    Document type Journal Article
    ISSN 1734-9338
    ISSN 1734-9338
    DOI 10.5114/aic.2023.131477
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  4. Article ; Online: Commentary: Extended Reality in Percutaneous Interventions: Toward a Revolution, but in Baby Steps.

    Grodecki, Kajetan / Huczek, Zenon / Filipiak, Krzysztof J

    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists

    2019  Volume 26, Issue 4, Page(s) 548–549

    MeSH term(s) Aortic Aneurysm, Abdominal/surgery ; Aortography ; Blood Vessel Prosthesis Implantation ; Endovascular Procedures ; Humans ; Treatment Outcome
    Language English
    Publishing date 2019-06-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2006618-1
    ISSN 1545-1550 ; 1526-6028
    ISSN (online) 1545-1550
    ISSN 1526-6028
    DOI 10.1177/1526602819855482
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  5. Article ; Online: Increased Plasma Concentrations of Extracellular Vesicles Are Associated with Pro-Inflammatory and Pro-Thrombotic Characteristics of Left and Right Ventricle Mechanical Support Devices.

    Urbanowicz, Tomasz / Olasińska-Wiśniewska, Anna / Grodecki, Kajetan / Gąsecka, Aleksandra / Filipiak, Krzysztof J / Gawlikowski, Maciej / Mucha, Łukasz / Jemielity, Marek

    Journal of cardiovascular development and disease

    2023  Volume 10, Issue 1

    Abstract: Mechanical circulatory support (MCS) allows for functional left and right heart ventricle replacement. MCS induces a systemic inflammatory reaction and prothrombotic state leading to an increased risk of thrombus formation. The extracellular vesicles ( ... ...

    Abstract Mechanical circulatory support (MCS) allows for functional left and right heart ventricle replacement. MCS induces a systemic inflammatory reaction and prothrombotic state leading to an increased risk of thrombus formation. The extracellular vesicles (EVs) are nanoparticles released from active/injured cells characterized by prothrombotic properties. Simple inflammatory parameters from whole blood count analysis have established a clinical role in everyday practice to describe immune-inflammatory activation. We hypothesized that increased plasma concentrations of EVs might be associated with the proinflammatory and pro-thrombotic characteristics of left ventricle assist device (LVAD) and right ventricle assist device (RVAD) devices. We presented a pilot study showing the concentration of peripheral blood serum, right and left ventricle mechanical assist device extracellular concentration in relation to thrombotic complication in patients treated with a biventricular pulsatile assist device (BIVAD). The observation was based on 12 replacements of pulsatile pumps during 175 days of observation. The proinflammatory characteristics of LVAD were noted. The proinflammatory and procoagulant activation by RVAD was observed. The results may provide possible explanations for the worse results of right-sided mechanical supports observed in clinical practice.
    Language English
    Publishing date 2023-01-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd10010021
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  6. Article: Red blood cell distribution width as a prognostic marker of prolonged mechanical ventilation after paediatric cardiac surgery.

    Olasińska-Wiśniewska, Anna / Urbanowicz, Tomasz / Gładki, Marcin / Grodecki, Kajetan / Michalak, Michał / Węclewska, Anita / Sochacki, Mateusz / Bobkowski, Waldemar / Zalas, Dominika / Jemielity, Marek

    Archives of medical science : AMS

    2023  Volume 19, Issue 3, Page(s) 825–828

    Language English
    Publishing date 2023-05-24
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2203781-0
    ISSN 1734-1922
    ISSN 1734-1922
    DOI 10.5114/aoms/161247
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  7. Article ; Online: Bioprosthetic Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction (BASILICA) in valve-in-valve Transcatheter Aortic Valve Implantation (ViV-TAVI): First experience in Poland.

    Jędrzejczyk, Szymon / Rymuza, Bartosz / Ścisło, Piotr / Grodecki, Kajetan / Pędzich-Placha, Ewa / Grabowski, Marcin / Kochman, Janusz / Huczek, Zenon

    Kardiologia polska

    2022  Volume 80, Issue 12, Page(s) 1266–1267

    MeSH term(s) Humans ; Transcatheter Aortic Valve Replacement/adverse effects ; Coronary Vessels ; Lacerations ; Poland ; Coronary Occlusion ; Aortic Valve/surgery ; Iatrogenic Disease/prevention & control ; Heart Valve Prosthesis/adverse effects ; Bioprosthesis/adverse effects ; Treatment Outcome ; Prosthesis Design ; Aortic Valve Stenosis/surgery
    Language English
    Publishing date 2022-09-26
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.a2022.0227
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  8. Article ; Online: Large unstained cells count is a useful predictor of coronary artery disease co-existence in patients with severe aortic stenosis.

    Urbanowicz, Tomasz / Olasińska-Wiśniewska, Anna / Grodecki, Kajetan / Fryska, Zuzanna / Komosa, Anna / Uruski, Paweł / Radziemski, Artur / Filipiak, Krzysztof J / Tykarski, Andrzej / Jemielity, Marek

    Kardiologia polska

    2022  Volume 81, Issue 7-8, Page(s) 769–771

    MeSH term(s) Humans ; Coronary Artery Disease/complications ; Coronary Artery Disease/diagnosis ; Patients ; Aortic Valve Stenosis/complications ; Aortic Valve Stenosis/surgery
    Language English
    Publishing date 2022-08-28
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.a2023.0111
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  9. Article ; Online: Monocyte-to-lymphocyte ratio correlates with parathyroid hormone concentration in patients with severe symptomatic aortic stenosis.

    Olasińska-Wiśniewska, Anna / Urbanowicz, Tomasz / Grodecki, Kajetan / Kübler, Piotr / Perek, Bartłomiej / Grygier, Marek / Misterski, Marcin / Walczak, Maciej / Szot, Mateusz / Jemielity, Marek

    Advances in medical sciences

    2023  Volume 68, Issue 2, Page(s) 396–401

    Abstract: Purpose: The normal healthy valve is devoid of inflammatory cells, however background of aortic stenosis (AS) may include inflammatory processes. Moreover, the link between hyperparathyroidism and heart failure is postulated. Simple whole blood analysis ...

    Abstract Purpose: The normal healthy valve is devoid of inflammatory cells, however background of aortic stenosis (AS) may include inflammatory processes. Moreover, the link between hyperparathyroidism and heart failure is postulated. Simple whole blood analysis with indices is a beneficial tool in cardiovascular diseases' assessment. The purpose of the study was to evaluate correlation between parathyroid hormone (PTH) and simple blood parameters in severe AS.
    Material and methods: The study included 62 patients with severe AS. Patients with inflammatory or autoimmune co-morbidities were excluded. Blood samples were collected, and clinical and demographic data were analyzed.
    Results: The final study group comprised 55 patients (31 females, 56.4%; mean age 77.13 (SD 6.76)). In 23 patients (41.8%), PTH concentration was markedly increased. The study group was divided into two subgroups according to the PTH concentration. Patients from both groups did not differ significantly in terms of age and co-morbidities. PTH concentration correlated positively with monocyte-lymphocyte ratio (MLR) (p ​= ​0.008, Spearman rho 0.356) and platelet-lymphocyte ratio (PLR) (p ​= ​0.047, Spearman rho 0.269), creatinine level (p ​= ​0.001, Spearman rho 0.425) and glomerular filtration rate (GFR-MDRD) (p ​= ​0.009, Spearman rho -0.349). The multivariable logistic regression with backward analysis revealed MLR (p ​= ​0.029) and GFR (p ​= ​0.028) as independent significant predictors of abnormal PTH values. The receiver operator characteristics (ROC) curve was performed for the model of MLR and GFR-MDRD (AUC ​= ​0.777), yielding the sensitivity of 60.9% and specificity of 90.6%.
    Conclusions: PTH concentration correlates with monocyte-to-lymphocyte and platelet-to-lymphocyte ratios in calcified AS.
    MeSH term(s) Female ; Humans ; Aged ; Monocytes ; Parathyroid Hormone ; Lymphocytes ; Blood Platelets ; Neutrophils ; Aortic Valve Stenosis/complications ; Retrospective Studies
    Chemical Substances Parathyroid Hormone
    Language English
    Publishing date 2023-10-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2273668-2
    ISSN 1898-4002 ; 1896-1126
    ISSN (online) 1898-4002
    ISSN 1896-1126
    DOI 10.1016/j.advms.2023.09.011
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  10. Article ; Online: Holographic imaging during transcatheter aortic valve implantation procedure in bicuspid aortic valve stenosis.

    Rymuza, Bartosz / Grodecki, Kajetan / Kamiński, Jakub / Scisło, Piotr / Huczek, Zenon

    Kardiologia polska

    2017  Volume 75, Issue 10, Page(s) 1056

    Language English
    Publishing date 2017
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.5603/KP.2017.0195
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