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  1. Article: Reply from j.p. Huelsenbeck, j.j. Bull and C.w. Cunningham.

    Huelsenbeck, J P / Bull, J J / Cunningham, C W

    Trends in ecology & evolution

    2011  Volume 11, Issue 8, Page(s) 335

    Language English
    Publishing date 2011-01-14
    Publishing country England
    Document type Letter
    ZDB-ID 284965-3
    ISSN 1872-8383 ; 0169-5347
    ISSN (online) 1872-8383
    ISSN 0169-5347
    DOI 10.1016/s0169-5347(96)91643-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  2. Article ; Online: Re: Chowdhury et al. 2011. J. Hazard. Mater. Disinfection byproducts in Canadian provinces: associated cancer risks and associated medical expenses. 187: 574-584.

    Bull, Richard J / Cotruvo, Joseph A / Fawell, John / Hrudey, Steve E

    Journal of hazardous materials

    2012  Volume 237-238, Page(s) 382–3; author reply 384–5

    MeSH term(s) Cost of Illness ; Disinfection ; Humans ; Neoplasms/chemically induced
    Language English
    Publishing date 2012-10-30
    Publishing country Netherlands
    Document type Comment ; Letter
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2011.07.040
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  3. Article ; Online: Dermacozines H-J isolated from a deep-sea strain of Dermacoccus abyssi from Mariana Trench sediments.

    Wagner, Marcell / Abdel-Mageed, Wael M / Ebel, Rainer / Bull, Alan T / Goodfellow, Michael / Fiedler, Hans-Peter / Jaspars, Marcel

    Journal of natural products

    2014  Volume 77, Issue 2, Page(s) 416–420

    Abstract: ... to the production of three new pigmented heteroaromatic (oxidized and reduced) phenazine compounds, dermacozines H-J ...

    Abstract Dermacoccus abyssi sp. nov. strains MT1.1 and MT1.2 are actinomycetes isolated from a Mariana Trench sediment at a depth of 10 898 m. The fermentation process using complex media led to the production of three new pigmented heteroaromatic (oxidized and reduced) phenazine compounds, dermacozines H-J (1-3). Extensive use was made of 1D and 2D NMR experiments and high-resolution MS to determine the structures of the compounds. The new dermacozines showed radical scavenging activity, and the highest activity was observed for dermacozine H (1), with an IC50 value of 18.8 μM.
    MeSH term(s) Actinomycetales/chemistry ; Biphenyl Compounds/pharmacology ; DNA, Bacterial/genetics ; Free Radical Scavengers/chemistry ; Free Radical Scavengers/isolation & purification ; Free Radical Scavengers/pharmacology ; Geologic Sediments/chemistry ; Inhibitory Concentration 50 ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Oxidation-Reduction ; Phenazines/chemistry ; Phenazines/isolation & purification ; Phenazines/pharmacology ; Phylogeny ; Picrates/pharmacology
    Chemical Substances Biphenyl Compounds ; DNA, Bacterial ; Free Radical Scavengers ; Phenazines ; Picrates ; dermacozine H ; 1,1-diphenyl-2-picrylhydrazyl (DFD3H4VGDH)
    Language English
    Publishing date 2014-02-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/np400952d
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1144: Show issues Location:
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  4. Book ; Online ; E-Book: Blast injury science and engineering

    Bull, Anthony M. J.

    a guide for clinicians and researchers

    2023  

    Abstract: This heavily revised second edition provides a comprehensive multi-disciplinary resource on blast injuries. It features detailed information on the basic science, engineering, and medicine associated with blast injuries. Clear, easy to understand ... ...

    Author's details Anthony M. J. Bull [and three others]
    Abstract This heavily revised second edition provides a comprehensive multi-disciplinary resource on blast injuries. It features detailed information on the basic science, engineering, and medicine associated with blast injuries. Clear, easy to understand descriptions of the basic science are accompanied by case studies of a variety of clinical problems including heterotopic ossification, hearing damage, and traumatic brain injury, enabling the reader to develop a deep understanding of how to appropriately apply the relevant science into their clinical practice. The use of prosthetics, orthotics and osseointegration in rehabilitation is also covered. Blast Injury Science and Engineering: A Guide for Clinicians and Researchers is a valuable interdisciplinary text primarily focused towards clinical medical professionals and trainees seeking to develop a thorough understanding of injury mechanisms, and the latest treatment techniques. In addition, this resource is of use to individuals in other fields whose work centres around blast injury science such as injury mitigation researchers, military scientists and engineers.
    Keywords Blast injuries ; Ferides i lesions
    Subject code 362.19719
    Language English
    Size 1 online resource (514 pages)
    Edition Second edition.
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-031-10355-6 ; 9783031103544 ; 978-3-031-10355-1 ; 3031103548
    DOI 10.1007/978-3-031-10355-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article: In regard to Vasanathan et al. (Int J Radiat Oncol Biol Phys 2005;61:145-153).

    Jones, Ellen L / Prosnitz, Leonard R / Dewhirst, Mark W / Vujaskovic, Zeljko / Samulski, Thaddeus V / Oleson, James R / Yu, Daohi / Myerson, Robert J / Moros, Eduardo G / Hurwitz, Mark D / Bull, Joan M C

    International journal of radiation oncology, biology, physics

    2005  Volume 63, Issue 2, Page(s) 644

    MeSH term(s) Combined Modality Therapy ; Female ; Humans ; Hyperthermia, Induced/methods ; Hyperthermia, Induced/standards ; Radiotherapy/standards ; Radiotherapy Dosage ; Uterine Cervical Neoplasms/radiotherapy ; Uterine Cervical Neoplasms/therapy
    Language English
    Publishing date 2005-10-01
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2005.06.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Dermacozines H–J Isolated from a Deep-Sea Strain of Dermacoccus abyssi from Mariana Trench Sediments

    Wagner, Marcell / Abdel-Mageed Wael M / Ebel Rainer / Bull Alan T / Goodfellow Michael / Fiedler Hans-Peter / Jaspars Marcel

    Journal of natural products. 2014 Feb. 28, v. 77, no. 2

    2014  

    Abstract: ... J (1–3). Extensive use was made of 1D and 2D NMR experiments and high-resolution MS to determine ...

    Abstract Dermacoccus abyssi sp. nov. strains MT1.1 and MT1.2 are actinomycetes isolated from a Mariana Trench sediment at a depth of 10 898 m. The fermentation process using complex media led to the production of three new pigmented heteroaromatic (oxidized and reduced) phenazine compounds, dermacozines H–J (1–3). Extensive use was made of 1D and 2D NMR experiments and high-resolution MS to determine the structures of the compounds. The new dermacozines showed radical scavenging activity, and the highest activity was observed for dermacozine H (1), with an IC₅₀ value of 18.8 μM.
    Keywords Dermacoccus ; antioxidant activity ; fermentation ; heterocyclic compounds ; inhibitory concentration 50 ; nuclear magnetic resonance spectroscopy ; sediments
    Language English
    Dates of publication 2014-0228
    Size p. 416-420.
    Publishing place American Chemical Society and American Society of Pharmacognosy
    Document type Article
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021%2Fnp400952d
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Carcinogenic effects of acrylamide in Sencar and A/J mice.

    Bull, R J / Robinson, M / Laurie, R D / Stoner, G D / Greisiger, E / Meier, J R / Stober, J

    Cancer research

    1984  Volume 44, Issue 1, Page(s) 107–111

    Abstract: ... for its ability to induce lung adenomas in the A/J mouse. Acrylamide was found to be without activity as a mutagen ... Acrylamide was also found to induce lung adenomas in male and female A/J mice using both the p.o. and i.p ...

    Abstract Acrylamide structurally resembles vinyl carbamate, a proposed proximate carcinogenic form of ethyl carbamate. To test the hypothesis that acrylamide should possess carcinogenic properties, it was tested in the Salmonella-microsome assay for point mutation, as a skin tumor initiator in the Sencar mouse, and for its ability to induce lung adenomas in the A/J mouse. Acrylamide was found to be without activity as a mutagen in Salmonella strains TA 1535, TA 1537, TA 98, and TA 100 both in the presence and absence of rat liver microsomes using both the plate and liquid suspension assays. However, acrylamide was found to approximate ethyl carbamate in potency as a tumor initiator in the skin of the female Sencar mice. As with ethyl carbamate, acrylamide was more potent by systemic routes of administration relative to topical application. Acrylamide was also found to induce lung adenomas in male and female A/J mice using both the p.o. and i.p. routes of administration. Acrylamide was approximately one-seventh as potent as ethyl carbamate in the induction of lung adenomas. These data confirm the hypothesis that acrylamide possesses carcinogenic properties similar to ethyl carbamate.
    MeSH term(s) Acrylamide ; Acrylamides/administration & dosage ; Acrylamides/toxicity ; Adenoma/chemically induced ; Administration, Oral ; Administration, Topical ; Animals ; Carcinogens ; Female ; Injections, Intraperitoneal ; Lung Neoplasms/chemically induced ; Mice ; Mice, Inbred A ; Mice, Inbred Strains ; Mutagenicity Tests ; Mutagens ; Salmonella typhimurium/drug effects ; Skin Neoplasms/chemically induced
    Chemical Substances Acrylamides ; Carcinogens ; Mutagens ; Acrylamide (20R035KLCI)
    Language English
    Publishing date 1984-01
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 1432-1
    ISSN 1538-7445 ; 0008-5472
    ISSN (online) 1538-7445
    ISSN 0008-5472
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    Uh III Zs.135/5: Show issues Location:
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  8. Article: Carcinogenic effects in A/J mice of particulate of a coal tar paint used in potable water systems.

    Robinson, M / Laurie, R D / Bull, R J / Stober, J A

    Cancer letters

    1987  Volume 34, Issue 1, Page(s) 49–54

    Abstract: ... with A/J mice. The paint was applied to clean glass plates, cured, collected and homogenized in 2% Emulphor ...

    Abstract Coal tar paints are among the products used as inside coatings for water pipes and storage tanks to retard corrosion in potable water supply systems. Four different formulations of these paints were tested in earlier work by this laboratory in the Ames mutagenesis and the mouse skin carcinogenesis bioassays. The paint most active in these assays were then tested in a particulate form in the lung adenoma assay with A/J mice. The paint was applied to clean glass plates, cured, collected and homogenized in 2% Emulphor. Doses of this coal tar suspension were administered by gavage at 1.0, 10.0 and 55.0 mg in 0.2 ml per mouse 3X weekly for 8 weeks. The total doses of coal tar paint were 24, 240, and 1320 mg/mouse. Benzo[a]pyrene (BaP), administered in a parallel schedule to a total dose of 6 mg/mouse, served as positive control. A negative control group received an equivalent volume of 2% Emulphor. Animals were killed at 9 months of age (8 months after first dose) and lung adenomas counted. A dose-related response, in the average number of lung tumors per mouse, was observed with the coal tar particulate. There were also squamous cell tumors of the forestomach in 42% of the mice receiving 55.0 mg coal tar paint per application.
    MeSH term(s) Animals ; Coal Tar/toxicity ; Female ; Lung Neoplasms/chemically induced ; Mice ; Neoplasms, Experimental/etiology ; Paint/analysis ; Paint/toxicity ; Stomach Neoplasms/chemically induced ; Water Supply/analysis
    Chemical Substances Coal Tar (8007-45-2)
    Language English
    Publishing date 1987-01
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 195674-7
    ISSN 1872-7980 ; 0304-3835
    ISSN (online) 1872-7980
    ISSN 0304-3835
    DOI 10.1016/0304-3835(87)90072-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1177: Show issues Location:
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  9. Book ; Online ; E-Book: People with multiple sclerosis

    Bull, Paul J.

    condition, challenges and care

    2015  

    Author's details Paul J. Bull
    Keywords Multiple Sclerosis ; Great Britain
    Subject code 616.8/34
    Language English
    Size 1 Online-Ressource (xiv, 305 Seiten)
    Publisher Palgrave Macmillan
    Publishing place Basingstoke
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT018976867
    ISBN 978-1-137-45705-9 ; 9781137457066 ; 1-137-45705-8 ; 1137457066
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Book ; Online: Planktic foraminiferal flux and faunal composition of sediment trap L1_K276 in the northeastern Atlantic, supplementary data to: Storz, David; Schulz, Hartmut; Waniek, Joanna J; Schulz-Bull, Detlef; Kucera, Michal (2009): Seasonal and interannual variability of the planktic foraminiferal flux in the vicinity of the Azores Current. Deep Sea Research Part I: Oceanographic Research Papers, 56(1), 107-124

    Storz, David / Kucera, Michal / Schulz, Hartmut / Schulz-Bull, Detlef / Waniek, Joanna J

    2009  

    Abstract: Planktic foraminiferal (PF) flux and faunal composition from three sediment trap time series of 2002-2004 in the northeastern Atlantic show pronounced year-to-year variations despite similar sea surface temperature (SST). The averaged fauna of the in ... ...

    Abstract Planktic foraminiferal (PF) flux and faunal composition from three sediment trap time series of 2002-2004 in the northeastern Atlantic show pronounced year-to-year variations despite similar sea surface temperature (SST). The averaged fauna of the in 2002/2003 is dominated by the species Globigerinita glutinata, whereas in 2003/2004 the averaged fauna is dominated by Globigerinoides ruber. We show that PF species respond primarily to productivity, triggered by the seasonal dynamics of vertical stratification of the upper water column. Multivariate statistical analysis reveals three distinct species groups, linked to bulk particle flux, to chlorophyll concentrations and to summer/fall oligotrophy with high SST and stratification. We speculate that the distinct nutrition strategies of strictly asymbiontic, facultatively symbiontic, and symbiontic species may play a key role in explaining their abundances and temporal succession. Advection of water masses within the Azores Current and species expatriation result in a highly diverse PF assemblage. The Azores Frontal Zone may have influenced the trap site in 2002, indicated by subsurface water cooling, by highest PF flux and high flux of the deep-dwelling species Globorotalia scitula. Similarity analyses with core top samples from the global ocean including 746 sites from the Atlantic suggest that the trap faunas have only poor analogs in the surface sediments. These differences have to be taken into account when estimating past oceanic properties from sediment PF data in the eastern subtropical North Atlantic.
    Language English
    Dates of publication 2009-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/j.dsr.2008.08.009
    DOI 10.1594/PANGAEA.724325
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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