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  1. Article: Second generation tyrosine kinase inhibitors for the treatment of chronic myelogenous leukemia. [An interview with Hagop Katarjian by H&O].

    Kantarjian, Hagop

    Clinical advances in hematology & oncology : H&O

    2009  Volume 6, Issue 11, Page(s) 797–799

    MeSH term(s) Antineoplastic Agents/therapeutic use ; Benzamides ; Dasatinib ; Humans ; Imatinib Mesylate ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Piperazines/therapeutic use ; Protein Kinase Inhibitors/therapeutic use ; Protein-Tyrosine Kinases/antagonists & inhibitors ; Pyrimidines/therapeutic use ; Thiazoles/therapeutic use
    Chemical Substances Antineoplastic Agents ; Benzamides ; Piperazines ; Protein Kinase Inhibitors ; Pyrimidines ; Thiazoles ; Imatinib Mesylate (8A1O1M485B) ; Protein-Tyrosine Kinases (EC 2.7.10.1) ; nilotinib (F41401512X) ; Dasatinib (RBZ1571X5H)
    Language English
    Publishing date 2009-02-03
    Publishing country United States
    Document type Interview
    ZDB-ID 2271951-9
    ISSN 1543-0790
    ISSN 1543-0790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online ; E-Book: Acute leukemias

    Faderl, Stefan H. / Kantarjian, Hagop / Estey, Elihu H.

    (Hematologic malignancies)

    2021  

    Author's details Stefan H. Faderl, Hagop M. Kantarjian, Elihu Estey editors
    Series title Hematologic malignancies
    Language English
    Size 1 Online-Ressource (vi, 289 Seiten), Illustrationen, Diagramme
    Edition Second edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020618612
    ISBN 978-3-030-53633-6 ; 9783030536329 ; 3-030-53633-5 ; 3030536327
    DOI 10.1007/978-3-030-53633-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: The MD Anderson manual of medical oncology

    Kantarjian, Hagop / Rieber, Alyssa G. / Wolff, Robert A.

    (McGraw-Hill's AccessMedicine)

    2022  

    Abstract: The new edition of The MD Anderson Manual of Medical Oncology contains new chapters on cord blood transplant, haploidentical stem cell transplantation, cellular therapy in allogeneic hematopoietic cell transplantation, pediatric cancers, molecular ... ...

    Institution University of Texas M.D. Anderson Cancer Center
    Author's details Hagop M. Kantarjian, Robert A. Wolff, Alyssa G. Rieber
    Series title McGraw-Hill's AccessMedicine
    Abstract The new edition of The MD Anderson Manual of Medical Oncology contains new chapters on cord blood transplant, haploidentical stem cell transplantation, cellular therapy in allogeneic hematopoietic cell transplantation, pediatric cancers, molecular biomarkers and cancer, immuno-oncology, targeted therapies in cancer, applied biostatistics, oncocardiology, pulmonary complications of cancer therapy, and cancer-associated thrombosis. In addition, there is expanded coverage of the rapidly growing areas of biological and immune therapies of cancer, with one chapter co-authored by our very own Nobel Laureate, Jim Allison.
    MeSH term(s) Medical Oncology. ; Neoplasms.
    Keywords Tumors ; Oncology
    Subject code 616.994
    Language English
    Size 1 online resource (1696 pages) :, color illustrations.
    Publisher McGraw Hill Medical
    Publishing place New York
    Document type Book ; Online ; E-Book
    Note English.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-260-46764-3 ; 978-1-260-46764-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book: The MD Anderson manual of medical oncology

    Wolff, Robert A. / Kantarjian, Hagop

    2016  

    Title variant Manual of medical oncology ; Medical oncology
    Institution M. D. Anderson Cancer Center
    Author's details editors Hagop M. Kantarjian, MD; Robert A. Wolff, MD
    Keywords Neoplasms ; Medical Oncology / methods
    Language English
    Size xxvii, 1251 Seiten, Illustrationen
    Edition Third edition
    Publisher McGraw-Hill
    Publishing place New York
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT019046663
    ISBN 978-0-07-184794-0 ; 0-07-184794-4
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: What is the impact of failing to achieve TKI therapy milestones in chronic myeloid leukemia.

    Kantarjian, Hagop M

    Leukemia

    2023  Volume 37, Issue 11, Page(s) 2324–2325

    MeSH term(s) Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/mortality ; Leukemia, Myeloid ; Chronic Disease
    Language English
    Publishing date 2023-10-05
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 807030-1
    ISSN 1476-5551 ; 0887-6924
    ISSN (online) 1476-5551
    ISSN 0887-6924
    DOI 10.1038/s41375-023-02053-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Targeting different pathways to prevent tumor cell development

    Kantarjian, Hagop

    (Seminars in oncology ; 36,2, Suppl. 1)

    2009  

    Author's details Hagop M. Kantarjian, guest ed
    Series title Seminars in oncology ; 36,2, Suppl. 1
    Collection
    Language English
    Size S58 S. : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT015962740
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Emil J. Freireich: Legend in cancer research (March 16, 1927-February 1, 2021).

    Kantarjian, Hagop

    Bone marrow transplantation

    2021  Volume 56, Issue 7, Page(s) 1764–1767

    Language English
    Publishing date 2021-05-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 632854-4
    ISSN 1476-5365 ; 0268-3369 ; 0951-3078
    ISSN (online) 1476-5365
    ISSN 0268-3369 ; 0951-3078
    DOI 10.1038/s41409-021-01284-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Integrating the new generation of targeted therapies for chronic myelogenous leukemia

    Kantarjian, Hagop

    (Seminars in hematology ; 44,1, Suppl. 1)

    2007  

    Author's details Hagop Kantarjian, guest ed
    Series title Seminars in hematology ; 44,1, Suppl. 1
    Collection
    Language English
    Size S34 S. : Ill.
    Publisher Saunders
    Publishing place Philadelphia, PA
    Publishing country United States
    Document type Book
    HBZ-ID HT015027301
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: Emil J. Freireich 1927-2021.

    Kantarjian, Hagop M

    Nature cancer

    2021  Volume 2, Issue 3, Page(s) 251–252

    Language English
    Publishing date 2021-07-19
    Publishing country England
    Document type Journal Article
    ISSN 2662-1347
    ISSN (online) 2662-1347
    DOI 10.1038/s43018-021-00188-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Navigating the Management of Chronic Phase CML in the Era of Generic BCR::ABL1 Tyrosine Kinase Inhibitors.

    Haddad, Fadi G / Kantarjian, Hagop

    Journal of the National Comprehensive Cancer Network : JNCCN

    2024  Volume 22, Issue 1

    Abstract: Over the past several years, advances in research, treatment, and market dynamics have impacted treatment strategies in chronic myeloid leukemia in chronic phase (CML-CP). They include the broader availability of cost-effective generic imatinib, and soon ...

    Abstract Over the past several years, advances in research, treatment, and market dynamics have impacted treatment strategies in chronic myeloid leukemia in chronic phase (CML-CP). They include the broader availability of cost-effective generic imatinib, and soon other generic second-generation tyrosine kinase inhibitors (TKIs). Access to affordable generics means that all patients with CML-CP should have access to safe and highly effective lifelong therapies. When overall survival is the treatment endpoint, imatinib provides a good treatment value. Second-generation TKIs may be the best frontline strategy when treatment-free remission is the goal. Recent studies have shown maintained efficacy and reduced toxicity when TKIs are used at reduced dosing. Reduced-dose schedules of second-generation TKIs (which are less toxic and induce faster deep molecular responses) may render generic second-generation TKIs a more attractive treatment option. Adjusting the dose of TKI in the presence of mild-to-moderate, or even severe but reversible, adverse events may be preferable to switching to a different TKI. The selection of second-line and beyond therapies depends on the evolving patterns observed with frontline treatment. Dose-adjusted ponatinib schedules have demonstrated improved efficacy and safety in patients resistant to second-generation TKIs or those with T315I-mutated disease. For asciminib, longer-term follow-up is needed to better evaluate its safety and efficacy compared with ponatinib. Allogeneic stem cell transplantation represents a valid alternative to newer-generation TKIs, with a better treatment value when TKIs are priced at >$40,000/year.
    MeSH term(s) Humans ; Imatinib Mesylate/therapeutic use ; Antineoplastic Agents/adverse effects ; Tyrosine Kinase Inhibitors ; Protein Kinase Inhibitors ; Leukemia, Myeloid, Chronic-Phase/drug therapy ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Drugs, Generic/therapeutic use ; Fusion Proteins, bcr-abl/genetics
    Chemical Substances Imatinib Mesylate (8A1O1M485B) ; Antineoplastic Agents ; Tyrosine Kinase Inhibitors ; Protein Kinase Inhibitors ; Drugs, Generic ; Fusion Proteins, bcr-abl (EC 2.7.10.2)
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2250759-0
    ISSN 1540-1413 ; 1540-1405
    ISSN (online) 1540-1413
    ISSN 1540-1405
    DOI 10.6004/jnccn.2023.7116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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