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Article ; Online: Erratum: KE JIANG, JIN-LONG REN, JUN-FENG GUO, ZENG WANG, LI DING1 amp; JIA-TANG LI (2020) A new species of the genus Dendrelaphis (Squamata: Colubridae) from Yunnan Province, China, with discussion of the occurrence of D. cyanochloris (Wall, 1921) in China. Zootaxa, 4743: 001-020.

Jiang, K E / Ren, Jin-Long / Guo, Jun-Feng / Wang, Zeng / Ding, L I / Li, Jia-Tang

Zootaxa

2020 Volume 4759, Issue 4, Page(s) zootaxa.4759.4.13

Language	English
Publishing date	2020-04-06
Publishing country	New Zealand
Document type	Journal Article ; Published Erratum
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.4759.4.13
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Response: Lind KE, Jorgensen ML. (2019). Clearing the air: why a link between Alzheimer's disease and air quality cannot be validly determined using prescription data in Australia.

Astell-Burt, Thomas / Feng, Xiaoqi

Health & place

2020 Volume 62, Page(s) 102195

MeSH term(s)	Air Pollution ; Alzheimer Disease ; Australia ; Humans ; Longitudinal Studies ; Middle Aged
Language	English
Publishing date	2020-05-27
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	1262540-1
ISSN	1873-2054 ; 1353-8292
ISSN (online)	1873-2054
ISSN	1353-8292
DOI	10.1016/j.healthplace.2019.102195
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Zs.A 4333: Show issues

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Article: [Effect of Kou Yan Qing Ke Li on the prevention and treatment of radiation-induced oral mucositis in patients with nasopharyngeal carcinoma].

Yun, Gong / Li, Zhang / Zehui, Feng / Xudong, He

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

2016 Volume 34, Issue 1, Page(s) 37–40

Abstract: Objective: The effect of Kou Yan Qing Ke Li on the prevention and treatment of radiation-induced ... control groups. The experimental group (30 patients) was treated with Kou Yan Qing Ke Li during the full course ... significant.: Conclusion: Kou Yan Qing Ke Li could delay the time of occurrence of radiation-induced oral ...

Abstract	Objective: The effect of Kou Yan Qing Ke Li on the prevention and treatment of radiation-induced oral mucositis was investigated in patients with nasopharyngeal carcinoma. Methods: Sixty patients with nasopharyngeal carcinoma to be treated with radiotherapy were randomized into two groups: the experimental and control groups. The experimental group (30 patients) was treated with Kou Yan Qing Ke Li during the full course of radiotherapy. The control group (30 patients) rinsed their mouths in the same way with mouth washes containing 0.9% sodium chloride injection, lidocaine, dexamethasone, vitamin B2 and B2 gargle liquid mixture, when grade 2 and above radiation-induced oral mucositis appeared in the process of radiation. Radiation-induced oral mucositis was assessed according to the radiation therapy oncology group criteria. The time of occurrence and degree of pain grade were compared between the two groups. Results: The first onset of oral mucositis in the experimental group (12.40 d ± 2.74 d) was later than that in the control group (9.46 d ± 1.39 d) (t = 5.241, P < 0.001), whereas the grade of pain and acute radiation mucositis was lower in the experimental group than that in the control group. The difference was statistically significant. Conclusion: Kou Yan Qing Ke Li could delay the time of occurrence of radiation-induced oral mucositis, reduce the severity of radiation stomatitis, alleviate the pain of patients, improve the clinical symptoms of patients, and effectively prevent and treat radiation-induced oral mucositis in patients with nasopharyngeal carcinoma.
MeSH term(s)	Carcinoma ; Humans ; Lidocaine ; Mouth Mucosa ; Mouthwashes ; Nasopharyngeal Carcinoma ; Nasopharyngeal Neoplasms ; Pain ; Radiation Injuries ; Stomatitis
Chemical Substances	Mouthwashes ; Lidocaine (98PI200987)
Language	Chinese
Publishing date	2016-06-01
Publishing country	China
Document type	Journal Article
ZDB-ID	1202342-5
ISSN	1000-1182
ISSN	1000-1182
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Zs.A 4073: Show issues

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Article ; Online: Deciphering the therapeutic mechanisms of Xiao-Ke-An in treatment of type 2 diabetes in mice by a Fangjiomics approach.

Yang, Zhen-zhong / Liu, Wei / Zhang, Feng / Li, Zheng / Cheng, Yi-yu

Acta pharmacologica Sinica

2015 Volume 36, Issue 6, Page(s) 699–707

Abstract: Aim: Xiao-Ke-An (XKA) is a traditional Chinese medicine (TCM) formula for the treatment of type 2 ...

Abstract	Aim: Xiao-Ke-An (XKA) is a traditional Chinese medicine (TCM) formula for the treatment of type 2 diabetes (T2D), and the effective ingredients and their targets as well as the mechanisms of XKA remain to be elucidated. In this study we investigated the therapeutic mechanisms of XKA in the treatment of T2D in mice using a Fangjiomics approach. Methods: KKAy mice feeding on a high-fat diet were used as models of T2D, and were orally treated with XKA (0.75 or 1.5 g · kg(-1) · d(-1)) for 32 d. Microarray mRNA expression data were obtained from the livers of the mice. Differentially expressed genes (DEGs) were identified by reverse rate analysis and ANOVA analysis. The compounds in XKA were identified by LC-MS analysis or collected from TCM databases. The relationships between the compounds and targets were established by combining the DEGs with information derived from mining literature or herb target databases. Relevant pathways were identified through a Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis using WebGestalt. Results: The compound-target-pathway network based on compounds identified by LC-MS analysis (NCA) included 20 constituent compounds, 46 targets and 36 T2D-related pathways, whereas the compound-target-pathway network based on compounds collected from databases (NCD) consisted of 40 compounds, 68 targets and 21 pathways. In the treatment of T2D, XKA might act mainly by improving carbohydrate and lipid metabolism, as well as ameliorating insulin resistance, inflammation and diabetic vascular complications. Conclusion: The network-based approach reveals complex therapeutic mechanisms of XKA in the treatment of T2D in mice that involve numerous compounds, targets, and signaling pathways.
MeSH term(s)	Administration, Oral ; Animals ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Chromatography, Liquid ; Cluster Analysis ; Data Mining ; Databases, Genetic ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Diet, High-Fat ; Disease Models, Animal ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/pharmacology ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Regulatory Networks ; Genomics/methods ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/pharmacology ; Liver/drug effects ; Liver/metabolism ; Male ; Mass Spectrometry ; Medicine, Chinese Traditional/methods ; Mice, Inbred C57BL ; Oligonucleotide Array Sequence Analysis ; Protein Interaction Maps ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction/drug effects ; Systems Biology/methods ; Systems Integration ; Time Factors
Chemical Substances	Blood Glucose ; Drugs, Chinese Herbal ; Hypoglycemic Agents ; RNA, Messenger ; Xiao-Ke-An
Language	English
Publishing date	2015-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1360774-1
ISSN	1745-7254 ; 0253-9756 ; 1671-4083
ISSN (online)	1745-7254
ISSN	0253-9756 ; 1671-4083
DOI	10.1038/aps.2014.138
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Zs.A 1904: Show issues

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Article ; Online: Evaluating the antidiabetic effects of Chinese herbal medicine: Xiao-Ke-An in 3T3-L1 cells and KKAy mice using both conventional and holistic omics approaches.

Yang, Zhenzhong / Wang, Linli / Zhang, Feng / Li, Zheng

BMC complementary and alternative medicine

2015 Volume 15, Page(s) 272

Abstract: Background: Xiao-Ke-An (XKA) is a Chinese medicine widely used for treating type 2 ...

Abstract	Background: Xiao-Ke-An (XKA) is a Chinese medicine widely used for treating type 2 diabetes mellitus (T2D). It is composed of eight herbal medicines traditionally used for T2D, including Rehmannia glutinosa Libosch, Anemarrhena asphodeloides Bunge, Coptis chinensis Franch, etc. The aim of the present study was to investigate the antidiabetic effects of XKA with both conventional and holistic omics approaches. Methods: The antidiabetic effect of XKA was first investigated in 3T3-L1 cells to study the effect of XKA on adipogenesis in vitro. Oil Red O staining was performed to determine the lipid accumulation. The intracellular total cholesterol (TC) and triglyceride (TG) contents in XKA treated 3T3-L1 cells were also evaluated. The therapeutic effects of XKA was further evaluated in KKAy mice with both conventional and holistic omics approaches. Body weight, fasting and non-fasting blood glucose, and oral glucose tolerance were measured during the experiment. At the time of sacrifice, serum was collected for the measurement of TG, TC, high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c). The liver, kidney, spleen, pancreas, heart and adipose tissues were harvested and weighted. The liver was used for further microarray experiment. Omics approaches were adopted to evaluate the holistic rebalancing effect of XKA at molecular network level. Results: XKA significantly inhibited adipogenic differentiation, lowered the intracellular TC and TG contents in 3T3-L1 cells. XKA improved the glucose homeostasis and lipid metabolism, ameliorated insulin resistance in KKAy mice. Furthermore, XKA also exhibited effective therapeutic effects by reversing the molecular T2D disease network from an unbalanced state. Conclusions: This study investigated the antidiabetic effects of XKA with both conventional and holistic omics approaches, providing both phenotypic evidence and underlying action mechanisms for the clinical use of XKA treating T2D.
MeSH term(s)	3T3-L1 Cells ; Animals ; Blood Glucose/drug effects ; Diabetes Mellitus, Experimental/drug therapy ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Insulin Resistance ; Lipid Metabolism/drug effects ; Mice
Chemical Substances	Blood Glucose ; Drugs, Chinese Herbal
Language	English
Publishing date	2015-08-13
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2050429-9
ISSN	1472-6882 ; 1472-6882
ISSN (online)	1472-6882
ISSN	1472-6882
DOI	10.1186/s12906-015-0785-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: [Prelimilary Study on Manipulative Resetting Pictures of Shang ke hui zuan (Collected Compilation of Traumatology)].

Yang, Yi-Zhou / Hu, Xiao-Feng

Zhonghua yi shi za zhi (Beijing, China : 1980)

2012 Volume 42, Issue 2, Page(s) 103–105

Abstract: Shang ke hui zuan (Collected Compilation of Traumatology) written by Hu Ting-guang, a famous doctor ...

Abstract	Shang ke hui zuan (Collected Compilation of Traumatology) written by Hu Ting-guang, a famous doctor in the Qing Dynasty, is a comprehensive traumatology book, which records 16 manual reduction pictures with a five-word verse in each one and 9 seven-word verses in Chapter 3 supplementing the former and vice versa. Vivid pictures and brief verses matched with each other are convenient to imitate and recite, and play a vital role in promotion of inheritance and transmission of manual reduction technique on traumatology.
Language	Chinese
Publishing date	2012-03
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	1052411-3
ISSN	0255-7053
ISSN	0255-7053
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Zs.A 4688: Show issues

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Article: [Treatment of arterial thrombotic diseases by academician CHEN Ke-Ji's therapeutic methods of disease identification and syndrome typing].

Xu, Feng-qin

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

2011 Volume 31, Issue 8, Page(s) 1021–1023

MeSH term(s)	Humans ; Medicine, Chinese Traditional/methods ; Thrombosis/therapy
Language	Chinese
Publishing date	2011-08
Publishing country	China
Document type	Journal Article
ZDB-ID	1195456-5
ISSN	1003-5370
ISSN	1003-5370
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.B 2863: Show issues

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Article ; Online: Estimating the plasma effect-site equilibrium rate constant (Ke₀) of propofol by fitting time of loss and recovery of consciousness.

Wu, Qi / Sun, Baozhu / Wang, Shuqin / Zhao, Lianying / Qi, Feng

Biological & pharmaceutical bulletin

2013 Volume 36, Issue 9, Page(s) 1420–1427

Abstract: The present paper proposes a new approach for fitting the plasma effect-site equilibrium rate constant (Ke0) of propofol to satisfy the condition that the effect-site concentration (Ce) is equal at the time of loss of consciousness (LOC) and recovery of ... ...

Abstract	The present paper proposes a new approach for fitting the plasma effect-site equilibrium rate constant (Ke0) of propofol to satisfy the condition that the effect-site concentration (Ce) is equal at the time of loss of consciousness (LOC) and recovery of consciousness (ROC). Forty patients receiving intravenous anesthesia were divided into 4 groups and injected propofol 1.4, 1.6, 1.8, or 2 mg/kg at 1,200 mL/h. Durations from the start of injection to LOC and to ROC were recorded. LOC and ROC were defined as an observer's assessment of alertness and sedation scale change from 3 to 2 and from 2 to 3, respectively. Software utilizing bisection method iteration algorithms was built. Then, Ke0 satisfying the CeLOC=CeROC condition was estimated. The accuracy of the Ke0 estimated by our method was compared with the Diprifusor TCI Pump built-in Ke0 (0.26 min(-1)), and the Orchestra Workstation built-in Ke0 (1.21 min(-1)) in another group of 21 patients who were injected propofol 1.4 to 2 mg/kg. Our results show that the population Ke0 of propofol was 0.53 ± 0.18 min(-1). The regression equation for adjustment by dose (mg/kg) and age was Ke0=1.42-0.30 × dose-0.0074 × age. Only Ke0 adjusted by dose and age achieved the level of accuracy required for clinical applications. We conclude that the Ke0 estimated based on clinical signs and the two-point fitting method significantly improved the ability of CeLOC to predict CeROC. However, only the Ke0 adjusted by dose and age and not a fixed Ke0 value can meet clinical requirements of accuracy.
MeSH term(s)	Adult ; Algorithms ; Anesthesia Recovery Period ; Anesthetics, Intravenous/administration & dosage ; Anesthetics, Intravenous/blood ; Anesthetics, Intravenous/pharmacokinetics ; Consciousness/drug effects ; Female ; Humans ; Infusions, Intravenous ; Male ; Middle Aged ; Propofol/administration & dosage ; Propofol/blood ; Propofol/pharmacokinetics ; Software
Chemical Substances	Anesthetics, Intravenous ; Propofol (YI7VU623SF)
Language	English
Publishing date	2013-06-27
Publishing country	Japan
Document type	Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1150271-x
ISSN	1347-5215 ; 0918-6158
ISSN (online)	1347-5215
ISSN	0918-6158
DOI	10.1248/bpb.b12-01093
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Zs.A 1474: Show issues

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Book ; Online: Friction, Vibration and Dynamic Properties of Transmission System under Wear Progression

Feng, Ke / Zheng, Jinde / Ni, Qing

2023

Keywords	Technology: general issues ; History of engineering & technology ; fault diagnosis ; rotating machinery ; EEMD ; probability density distribution ; statistical distance ; mechanical parts ; fault state detection ; sliding dispersion entropy ; feature extraction ; checkvalve ; local mean decomposition ; wavelet packet transform ; K-L divergence ; variational mode decomposition (VMD) ; information entropy ; robust independent component analysis (RobustICA) ; fault feature extraction ; rolling bearing ; autoencoder network ; multisensor ; feature fusion ; n/a ; internal turning ; internal spray cooling ; tool design ; CFD simulations ; green cutting ; coupling effects ; dynamic model ; gear wear ; wear prediction ; KPLS ; KELM ; check valve ; bearing ; fast complementary ensemble empirical mode decomposition ; energy kurtosis mean filtering ; multipoint optimal minimum entropy deconvolution adjusted ; inter-shaft bearings ; local defects ; time-varying displacement ; elasto-hydrodynamic lubrication ; defect widths
Language	English
Size	1 electronic resource (196 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030379039
ISBN	9783036562582 ; 3036562583
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Evaluating the antidiabetic effects of Chinese herbal medicine: Xiao-Ke-An in 3T3-L1 cells and KKAy mice using both conventional and holistic omics approaches

Yang, Zhenzhong / Wang, Linli / Zhang, Feng / Li, Zheng

BMC Complement Altern Med. 2015 Dec., v. 15, no. 1 p.272-272

2015

Abstract: BACKGROUND: Xiao-Ke-An (XKA) is a Chinese medicine widely used for treating type 2 ...

Abstract	BACKGROUND: Xiao-Ke-An (XKA) is a Chinese medicine widely used for treating type 2 diabetes mellitus (T2D). It is composed of eight herbal medicines traditionally used for T2D, including Rehmannia glutinosa Libosch, Anemarrhena asphodeloides Bunge, Coptis chinensis Franch, etc. The aim of the present study was to investigate the antidiabetic effects of XKA with both conventional and holistic omics approaches. METHODS: The antidiabetic effect of XKA was first investigated in 3T3-L1 cells to study the effect of XKA on adipogenesis in vitro. Oil Red O staining was performed to determine the lipid accumulation. The intracellular total cholesterol (TC) and triglyceride (TG) contents in XKA treated 3T3-L1 cells were also evaluated. The therapeutic effects of XKA was further evaluated in KKAy mice with both conventional and holistic omics approaches. Body weight, fasting and non-fasting blood glucose, and oral glucose tolerance were measured during the experiment. At the time of sacrifice, serum was collected for the measurement of TG, TC, high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c). The liver, kidney, spleen, pancreas, heart and adipose tissues were harvested and weighted. The liver was used for further microarray experiment. Omics approaches were adopted to evaluate the holistic rebalancing effect of XKA at molecular network level. RESULTS: XKA significantly inhibited adipogenic differentiation, lowered the intracellular TC and TG contents in 3T3-L1 cells. XKA improved the glucose homeostasis and lipid metabolism, ameliorated insulin resistance in KKAy mice. Futhermore, XKA also exhibited effective therapeutic effects by reversing the molecualr T2D disease network from an unbalanced state. CONCLUSIONS: This study investigated the antidiabetic effects of XKA with both conventional and holistic omics approaches, providing both phenotypic evidence and underlying action mechanisms for the clinical use of XKA treating T2D.
Keywords	Anemarrhena asphodeloides ; Coptis chinensis ; Oriental traditional medicine ; Rehmannia glutinosa ; adipogenesis ; blood glucose ; blood serum ; body weight ; complement ; glucose ; glucose tolerance ; glycemic effect ; heart ; herbal medicines ; high density lipoprotein cholesterol ; homeostasis ; insulin resistance ; kidneys ; lipid metabolism ; liver ; low density lipoprotein cholesterol ; microarray technology ; noninsulin-dependent diabetes mellitus ; pancreas ; phenotype ; spleen ; therapeutics ; triacylglycerols
Language	English
Dates of publication	2015-12
Size	p. 272.
Publishing place	BioMed Central
Document type	Article ; Online
ZDB-ID	2050429-9
ISSN	1472-6882
ISSN	1472-6882
DOI	10.1186/s12906-015-0785-2
Database	NAL-Catalogue (AGRICOLA)

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