Article ; Online: Utilisation des modèles murins pour l’étude du syndrome d’apnées obstructives du sommeil dans le syndrome de Down.
Revue des maladies respiratoires
2024 Volume 41, Issue 4, Page(s) 279–282
Abstract: Down syndrome (DS), or trisomy 21, is a genetic disorder caused by the presence of an extra copy of chromosome 21, leading to various characteristic physical features as well as developmental and cognitive delays. Obstructive sleep apnea syndrome (OSAS) ... ...
Title translation | Use of murine models for the study of obstructive sleep apnea syndrome in Down syndrome. |
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Abstract | Down syndrome (DS), or trisomy 21, is a genetic disorder caused by the presence of an extra copy of chromosome 21, leading to various characteristic physical features as well as developmental and cognitive delays. Obstructive sleep apnea syndrome (OSAS) is a common disorder in both adult and pediatric patients with DS. Several characteristics of DS may contribute to the development or worsening of OSAS. Numerous murine models of DS exist. A number of studies have explored apneas and the risk of upper airway obstruction in these models, but up until now, only in adulthood. |
MeSH term(s) | Adult ; Humans ; Animals ; Child ; Mice ; Down Syndrome/complications ; Disease Models, Animal ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Continuous Positive Airway Pressure |
Language | French |
Publishing date | 2024-03-08 |
Publishing country | France |
Document type | English Abstract ; Journal Article |
ZDB-ID | 605743-3 |
ISSN | 1776-2588 ; 0301-0279 ; 0761-8425 |
ISSN (online) | 1776-2588 |
ISSN | 0301-0279 ; 0761-8425 |
DOI | 10.1016/j.rmr.2024.02.010 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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