LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 27

Search options

  1. Article ; Online: BiTE-ing into Prostate Cancer with Bispecific T-cell Engagers.

    Kamat, Nikhil V / Yu, Evan Y / Lee, John K

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2021  Volume 27, Issue 10, Page(s) 2675–2677

    Abstract: Targeting prostate-specific membrane antigen (PSMA) has important therapeutic ramifications, more recently including immune oncology. Data were recently presented on the preclinical efficacy of a half-life extended bispecific T-cell engager, AMG 160, ... ...

    Abstract Targeting prostate-specific membrane antigen (PSMA) has important therapeutic ramifications, more recently including immune oncology. Data were recently presented on the preclinical efficacy of a half-life extended bispecific T-cell engager, AMG 160, which binds PSMA and CD3 to induce T-cell-driven cytolytic activity against prostate cancer.
    MeSH term(s) Antibodies, Bispecific ; CD3 Complex ; Humans ; Male ; Prostatic Neoplasms/drug therapy ; T-Lymphocytes
    Chemical Substances Antibodies, Bispecific ; CD3 Complex
    Language English
    Publishing date 2021-03-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-21-0355
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4223: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Mitral Annulus Disjunction and Arrhythmic Mitral Valve Prolapse: Emerging Role of Cardiac Magnetic Resonance Imaging in the Workup.

    Kulkarni, Amol A / Chudgar, Priya D / Burkule, Nitin J / Kamat, Nikhil V

    The Indian journal of radiology & imaging

    2022  Volume 32, Issue 4, Page(s) 576–581

    Abstract: Mitral valve prolapse is a commonly described entity with a highly variable and benign course. However, it is associated with ventricular arrhythmias and sudden cardiac death in a small subset of patients. Recent studies have yielded insight into ... ...

    Abstract Mitral valve prolapse is a commonly described entity with a highly variable and benign course. However, it is associated with ventricular arrhythmias and sudden cardiac death in a small subset of patients. Recent studies have yielded insight into myocardial mechanics and the causation of ventricular arrhythmias in these groups of patients. Mitral annular disjunction (MAD) characterized by detachment of mitral annulus from left ventricular myocardium is associated with morphological and functional remodeling of the left ventricular myocardium. Resultant fibrosis acts as a substrate of ventricular arrhythmia and sudden cardiac death. We present two such cases of arrhythmic mitral valve prolapse associated with MAD. Cardiac magnetic resonance imaging provides excellent morphological information and also helps in the assessment of fibrosis.
    Language English
    Publishing date 2022-08-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 605869-3
    ISSN 0971-3026 ; 0970-2016
    ISSN 0971-3026 ; 0970-2016
    DOI 10.1055/s-0042-1754357
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 430: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Myocardial Strain Imaging Using Feature Tracking Method of Cardiac MRI: Our Initial Experience of This Novel Parameter as an Additional Diagnostic Tool.

    Chudgar, Priya D / Burkule, Nitin J / Kamat, Nikhil V / Rege, Gautam M / Jantre, Mansi N

    The Indian journal of radiology & imaging

    2022  Volume 32, Issue 4, Page(s) 479–487

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2022-08-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 605869-3
    ISSN 0971-3026 ; 0970-2016
    ISSN 0971-3026 ; 0970-2016
    DOI 10.1055/s-0042-1748760
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 430: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Utility of 3D CT Rib Study in Presurgical Planning of Autologous Ear Graft for Pinna Reconstruction in Microtia.

    Zanje, Sneha S / Kamat, Nikhil V / Taware, Kunal K / Rokade, M L / Bhumkar, Ashesh C

    The Indian journal of radiology & imaging

    2021  Volume 31, Issue 3, Page(s) 586–595

    Abstract: ... ...

    Abstract Purpose
    Language English
    Publishing date 2021-10-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 605869-3
    ISSN 0971-3026 ; 0970-2016
    ISSN 0971-3026 ; 0970-2016
    DOI 10.1055/s-0041-1735866
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 430: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Mitral Annulus Disjunction and Arrhythmic Mitral Valve Prolapse

    Amol A. Kulkarni / Priya D. Chudgar / Nitin J. Burkule / Nikhil V. Kamat

    Indian Journal of Radiology and Imaging, Vol 32, Iss 04, Pp 576-

    Emerging Role of Cardiac Magnetic Resonance Imaging in the Workup

    2022  Volume 581

    Abstract: Mitral valve prolapse is a commonly described entity with a highly variable and benign course. However, it is associated with ventricular arrhythmias and sudden cardiac death in a small subset of patients. Recent studies have yielded insight into ... ...

    Abstract Mitral valve prolapse is a commonly described entity with a highly variable and benign course. However, it is associated with ventricular arrhythmias and sudden cardiac death in a small subset of patients. Recent studies have yielded insight into myocardial mechanics and the causation of ventricular arrhythmias in these groups of patients. Mitral annular disjunction (MAD) characterized by detachment of mitral annulus from left ventricular myocardium is associated with morphological and functional remodeling of the left ventricular myocardium. Resultant fibrosis acts as a substrate of ventricular arrhythmia and sudden cardiac death. We present two such cases of arrhythmic mitral valve prolapse associated with MAD. Cardiac magnetic resonance imaging provides excellent morphological information and also helps in the assessment of fibrosis.
    Keywords mitral regurgitation ; mitral valve prolapse ; mitral annulus disjunction ; cardiac mri ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 610
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Mitral Annulus Disjunction and Arrhythmic Mitral Valve Prolapse: Emerging Role of Cardiac Magnetic Resonance Imaging in the Workup

    Kulkarni, Amol A. / Chudgar, Priya D. / Burkule, Nitin J. / Kamat, Nikhil V.

    Indian Journal of Radiology and Imaging

    2022  Volume 32, Issue 04, Page(s) 576–581

    Abstract: Mitral valve prolapse is a commonly described entity with a highly variable and benign course. However, it is associated with ventricular arrhythmias and sudden cardiac death in a small subset of patients. Recent studies have yielded insight into ... ...

    Abstract Mitral valve prolapse is a commonly described entity with a highly variable and benign course. However, it is associated with ventricular arrhythmias and sudden cardiac death in a small subset of patients. Recent studies have yielded insight into myocardial mechanics and the causation of ventricular arrhythmias in these groups of patients. Mitral annular disjunction (MAD) characterized by detachment of mitral annulus from left ventricular myocardium is associated with morphological and functional remodeling of the left ventricular myocardium. Resultant fibrosis acts as a substrate of ventricular arrhythmia and sudden cardiac death. We present two such cases of arrhythmic mitral valve prolapse associated with MAD. Cardiac magnetic resonance imaging provides excellent morphological information and also helps in the assessment of fibrosis.
    Keywords mitral regurgitation ; mitral valve prolapse ; mitral annulus disjunction ; cardiac MRI
    Language English
    Publishing date 2022-08-30
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 605869-3
    ISSN 1998-3808 ; 0971-3026 ; 0970-2016
    ISSN (online) 1998-3808
    ISSN 0971-3026 ; 0970-2016
    DOI 10.1055/s-0042-1754357
    Database Thieme publisher's database

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 430: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Lumbar Cryptorchidism with Splenogonadal Fusion

    Amol Anil Kulkarni / Ajay S. Kanbur / Nikhil V. Kamat / Lokesh D. Sinha / Prashant Khadse / Riya Prakash Mehta

    Journal of Gastrointestinal and Abdominal Radiology, Vol 05, Iss 01, Pp 049-

    The Odd Couple

    2022  Volume 054

    Abstract: We present and discuss the clinical, radiological, surgical, and histopathologic findings in a 16-month-old child who presented with bilateral cryptorchidism. He was investigated radiologically with ultrasonography and magnetic resonance imaging, ... ...

    Abstract We present and discuss the clinical, radiological, surgical, and histopathologic findings in a 16-month-old child who presented with bilateral cryptorchidism. He was investigated radiologically with ultrasonography and magnetic resonance imaging, diagnosed with small right inguinal and an enlarged left abdominal testis, and he underwent left orchidectomy and histopathology confirmed the diagnosis of splenogonadal fusion.
    Keywords splenogonadal fusion ; bilateral cryptorchidism ; mri ; Internal medicine ; RC31-1245 ; Diseases of the digestive system. Gastroenterology ; RC799-869
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Myocardial Strain Imaging Using Feature Tracking Method of Cardiac MRI

    Priya D. Chudgar / Nitin J. Burkule / Nikhil V. Kamat / Gautam M. Rege / Mansi N. Jantre

    Indian Journal of Radiology and Imaging, Vol 32, Iss 04, Pp 479-

    Our Initial Experience of This Novel Parameter as an Additional Diagnostic Tool

    2022  Volume 487

    Abstract: Background Left ventricular ejection fraction (LVEF) is used as quantitative parameter to evaluate myocardial function. However, interobserver variation, limited reproducibility, and dependence on pre-load and after-load reduces its accuracy. The fall in ...

    Abstract Background Left ventricular ejection fraction (LVEF) is used as quantitative parameter to evaluate myocardial function. However, interobserver variation, limited reproducibility, and dependence on pre-load and after-load reduces its accuracy. The fall in LVEF occurs very late, when myocardial dysfunction is already advanced. Myocardial strain measurements (especially global longitudinal strain) is a new parameter to detect myocardial dysfunction before derangements in LVEF. The aim of this article is to share our experience of this novel diagnostic tool. Methods Feature tracking method of strain assessment is performed using routine long and short axis cine images of cardiac MRI (CMR). Dedicated post-processing CMR software can perform off-line analysis and provide results in form of color-coded maps, percentage values as well as strain over time curve for each myocardial segments. Results Global longitudinal strain (GLS) is more sensitive than LVEF and can identify sub-clinical left ventricular (LV) dysfunction in various cardiomyopathies. It is also an important prognostic marker in serial assessment of heart failure patients. Regional differences in strain parameters can provide clues in hypertrophic cardiomyopathy as well as amyloidosis. GLS is recommended as routine measurement in patients undergoing chemotherapy to detect LV dysfunction prior to fall in LVEF. Strain imaging can be applied to guide placement of the LV pacing lead in patients receiving cardiac resynchronization therapy. More clinical data is needed to evaluate its role in ischemic heart disease. Conclusion Strain imaging can identify LV dysfunction earlier than conventional methods and this opens a new perspective in risk stratification and therapeutic decision-making of various cardiac pathologies.
    Keywords myocardial strain ; feature tracking ; cardiac magnetic resonance imaging ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 610
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article: Myocardial Strain Imaging Using Feature Tracking Method of Cardiac MRI: Our Initial Experience of This Novel Parameter as an Additional Diagnostic Tool

    Chudgar, Priya D. / Burkule, Nitin J. / Kamat, Nikhil V. / Rege, Gautam M. / Jantre, Mansi N.

    Indian Journal of Radiology and Imaging

    2022  Volume 32, Issue 04, Page(s) 479–487

    Abstract: Background: Left ventricular ejection fraction (LVEF) is used as quantitative parameter to evaluate myocardial function. However, interobserver variation, limited reproducibility, and dependence on pre-load and after-load reduces its accuracy. The fall ... ...

    Abstract Background: Left ventricular ejection fraction (LVEF) is used as quantitative parameter to evaluate myocardial function. However, interobserver variation, limited reproducibility, and dependence on pre-load and after-load reduces its accuracy. The fall in LVEF occurs very late, when myocardial dysfunction is already advanced. Myocardial strain measurements (especially global longitudinal strain) is a new parameter to detect myocardial dysfunction before derangements in LVEF. The aim of this article is to share our experience of this novel diagnostic tool.
    Methods: Feature tracking method of strain assessment is performed using routine long and short axis cine images of cardiac MRI (CMR). Dedicated post-processing CMR software can perform off-line analysis and provide results in form of color-coded maps, percentage values as well as strain over time curve for each myocardial segments.
    Results: Global longitudinal strain (GLS) is more sensitive than LVEF and can identify sub-clinical left ventricular (LV) dysfunction in various cardiomyopathies. It is also an important prognostic marker in serial assessment of heart failure patients. Regional differences in strain parameters can provide clues in hypertrophic cardiomyopathy as well as amyloidosis. GLS is recommended as routine measurement in patients undergoing chemotherapy to detect LV dysfunction prior to fall in LVEF. Strain imaging can be applied to guide placement of the LV pacing lead in patients receiving cardiac resynchronization therapy. More clinical data is needed to evaluate its role in ischemic heart disease.
    Conclusion: Strain imaging can identify LV dysfunction earlier than conventional methods and this opens a new perspective in risk stratification and therapeutic decision-making of various cardiac pathologies.
    Keywords myocardial strain ; feature tracking ; cardiac magnetic resonance imaging
    Language English
    Publishing date 2022-08-30
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 605869-3
    ISSN 1998-3808 ; 0971-3026 ; 0970-2016
    ISSN (online) 1998-3808
    ISSN 0971-3026 ; 0970-2016
    DOI 10.1055/s-0042-1748760
    Database Thieme publisher's database

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 430: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Lumbar Cryptorchidism with Splenogonadal Fusion: The Odd Couple

    Kulkarni, Amol Anil / Kanbur, Ajay S. / Kamat, Nikhil V. / Sinha, Lokesh D. / Khadse, Prashant / Mehta, Riya Prakash

    Journal of Gastrointestinal and Abdominal Radiology

    2022  Volume 05, Issue 01, Page(s) 49–54

    Abstract: We present and discuss the clinical, radiological, surgical, and histopathologic findings in a 16-month-old child who presented with bilateral cryptorchidism. He was investigated radiologically with ultrasonography and magnetic resonance imaging, ... ...

    Abstract We present and discuss the clinical, radiological, surgical, and histopathologic findings in a 16-month-old child who presented with bilateral cryptorchidism. He was investigated radiologically with ultrasonography and magnetic resonance imaging, diagnosed with small right inguinal and an enlarged left abdominal testis, and he underwent left orchidectomy and histopathology confirmed the diagnosis of splenogonadal fusion.
    Keywords splenogonadal fusion ; bilateral cryptorchidism ; MRI
    Language English
    Publishing date 2022-01-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 2581-9178
    ISSN (online) 2581-9178
    DOI 10.1055/s-0041-1740477
    Database Thieme publisher's database

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top