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Article ; Online: HBB as a Novel Biomarker for the Diagnosis and Monitoring of Lung Cancer Regulates Cell Proliferation via ERK1/2 Pathway.

Xu, Xinxin / Cai, Hua / Peng, Jingjing / Liu, Hongli / Chu, Fuying

Technology in cancer research & treatment

2024 Volume 23, Page(s) 15330338241249032

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/pathology ; Lung Neoplasms/metabolism ; Lung Neoplasms/genetics ; Biomarkers, Tumor ; Cell Proliferation ; Female ; Male ; MAP Kinase Signaling System ; Middle Aged ; ROC Curve ; Cell Line, Tumor ; Aged ; Hemoglobins/metabolism ; Gene Expression Regulation, Neoplastic ; Neoplasm Staging ; Prognosis ; Adult
Chemical Substances	Biomarkers, Tumor ; Hemoglobins
Language	English
Publishing date	2024-04-29
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2146365-7
ISSN	1533-0338 ; 1533-0346
ISSN (online)	1533-0338
ISSN	1533-0346
DOI	10.1177/15330338241249032
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Article: Uterine cervical Müllerian adenosarcoma possibly arising from ovarian cystadenofibroma: A case report and review of the literature.

Zhu, Xinxin / Peng, Chao / Huang, Yan / Zhou, Yingfang

Frontiers in oncology

2023 Volume 12, Page(s) 1064851

Abstract: Uterine cervical Müllerian adenosarcoma (MA), a rare malignant tumor of the female reproductive organs, is composed of a benign epithelium and a low-grade malignant stromal component. Because few studies have investigated the clinical management of MA, ... ...

Abstract	Uterine cervical Müllerian adenosarcoma (MA), a rare malignant tumor of the female reproductive organs, is composed of a benign epithelium and a low-grade malignant stromal component. Because few studies have investigated the clinical management of MA, misdiagnosis often occur. Therefore, we proposed an optimal course of clinical management for patients with MA. MA is possibly a malignant transformation of the cystadenofibroma. In this study, we present a case of a 46-year-old woman who presented with symptoms of MA of the uterine cervix, such as metrorrhagia and a cyst in the cervical canals, after transvaginal excision of the left ovarian mucinous cystadenofibroma.
Language	English
Publishing date	2023-01-04
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2022.1064851
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Article ; Online: Sex Differences in Outcomes of Hepatobiliary and Pancreatic Surgery with Accelerated Rehabilitation.

Zhang, Xinxin / Wang, Qian / Zhang, Min / Chen, Liguang / Peng, Danhong

Annali italiani di chirurgia

2024 Volume 95, Issue 2, Page(s) 166–173

Abstract: Background: Sex, in the sense of gender, is a major social demographic characteristic that has been shown to affect health care outcomes. The concept of enhanced recovery after surgery (ERAS) is an effective perioperative management measure that can ... ...

Abstract	Background: Sex, in the sense of gender, is a major social demographic characteristic that has been shown to affect health care outcomes. The concept of enhanced recovery after surgery (ERAS) is an effective perioperative management measure that can reduce the perioperative stress response in patients. However, there are few studies on the differences between male and female patients under this type of care. We aimed to analyze sex differences in clinical characteristics among patients undergoing hepatobiliary and pancreatic surgery with accelerated rehabilitation. Methods: We enrolled patients who underwent liver, biliary tract, and gallbladder operations in the Department of Hepatobiliary and Pancreatic Surgery of Taizhou Hospital, Zhejiang Province, China, from April 2021 to July 2021. Key measures were collected for patients undergoing perioperative accelerated rehabilitation (i.e., the case group). The study group was assembled by performing 1:1 matching for age, sex, chronic disease, and type of surgery. Postoperative risk assessment, postoperative recovery indicators, and postoperative length of hospital stay (days) were compared between male and female patients. Results: A total of 226 surgical patients were enrolled, including 109 male (48.23%) and 117 female patients (51.77%). The outcomes, presented as the median (min, max), were as follows: pulmonary rehabilitation risk assessment in females (1(0,3)) and males (0(0,2)), postoperative nausea and vomiting in females (2(1,3)) and males (1(0,2)), and time to first defecation in females (31(4,61)) and males (36(10,78)). Significant differences were indicated by p values < 0.05. Conclusion: We identified sex differences in the clinical prognosis and performance of perioperative patients undergoing hepatobiliary and pancreatic surgery with accelerated rehabilitation. The perioperative pulmonary rehabilitation risk of male patients was higher than that of female patients, and the time to first defecation was longer in male than in female patients. The incidence of nausea and vomiting in women was higher than in men.
MeSH term(s)	Humans ; Male ; Female ; Middle Aged ; Sex Factors ; Length of Stay/statistics & numerical data ; Aged ; Enhanced Recovery After Surgery ; Treatment Outcome ; Biliary Tract Surgical Procedures/methods ; Postoperative Complications/epidemiology ; Adult ; Risk Assessment
Language	English
Publishing date	2024-04-29
Publishing country	Italy
Document type	Journal Article ; Comparative Study
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
DOI	10.62713/aic.3169
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Article: Increasing the sensor channels: a solution for the pressing offsets that cause the physiological parameter inaccuracy in radial artery pulse signal acquisition.

Chen, Chao / Chen, Zhendong / Luo, Hongmiin / Peng, Bo / Hao, Yinan / Xie, Xiaohua / Xie, Haiqing / Li, Xinxin

Frontiers in bioengineering and biotechnology

2024 Volume 12, Page(s) 1359297

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2024-02-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2719493-0
ISSN	2296-4185
ISSN	2296-4185
DOI	10.3389/fbioe.2024.1359297
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Article: Socioeconomic inequality in public satisfaction with the healthcare system in China: a quantile regression analysis.

Peng, XinXin / Zhang, Jing Hua

Archives of public health = Archives belges de sante publique

2022 Volume 80, Issue 1, Page(s) 165

Abstract: Background: As China pursues better social equality and improvement in public services (healthcare), public satisfaction has been considered as a key performance indicator. There is a great need to better understand the disparities and inequalities in ... ...

Abstract	Background: As China pursues better social equality and improvement in public services (healthcare), public satisfaction has been considered as a key performance indicator. There is a great need to better understand the disparities and inequalities in the public satisfaction with its healthcare system. Methods: Based on Chinese General Social Survey (CGSS) 2015 ( a set of nationally representative survey data, the most recent wave containing information about public satisfaction with the healthcare system), this study utilizes the quantile regression method to analyze how the public satisfaction at high or low quantile of the score distribution varies according to the socio-economic status and healthcare system performance indicators, especially in rural areas. Results: This study found that, at the highest percentile, better Self-Reported-Health (SRH) is associated significantly with a lower satisfaction score (coefficient -4.10, P < 0.01). High socioeconomic status (especially "above average" group) has higher satisfaction scores at both mean (coefficient 3.74, P<0.01) and median (coefficient 3.83, P<0.01). This effect is also significant across the lower quantiles of the satisfaction levels. West and Middle region (the less developed regions) tended to be more satisfied, whereas those in Northeast reported a large negative effect (coefficient -7.07, P < 0.01) at the median. While rural residents generally reported higher levels of satisfaction, rural residents' preference regarding hospital beds and primary care access seems generally to be opposite to that of urban residents. Conclusion: Our findings suggest that the ongoing healthcare reform needs to integrate more preventive care to meet the healthy residents' expectation and demands. More attention should be guided to the vulnerable healthcare system in the Northeast region, which has a stagnant local economy. Outcome-based quality care is especially preferred in rural healthcare, in addition to improvement of utilization and access. In addition, the "pro-rich" inequality is an ongoing concern about the system.
Language	English
Publishing date	2022-07-08
Publishing country	England
Document type	Journal Article
ZDB-ID	1117688-x
ISSN	2049-3258 ; 0778-7367 ; 0003-9578
ISSN (online)	2049-3258
ISSN	0778-7367 ; 0003-9578
DOI	10.1186/s13690-022-00925-z
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Article ; Online: Context Enhancing Representation for Semantic Segmentation in Remote Sensing Images.

Fang, Leyuan / Zhou, Peng / Liu, Xinxin / Ghamisi, Pedram / Chen, Siwei

IEEE transactions on neural networks and learning systems

2024 Volume 35, Issue 3, Page(s) 4138–4152

Abstract: As the foundation of image interpretation, semantic segmentation is an active topic in the field of remote sensing. Facing the complex combination of multiscale objects existing in remote sensing images (RSIs), the exploration and modeling of contextual ... ...

Abstract	As the foundation of image interpretation, semantic segmentation is an active topic in the field of remote sensing. Facing the complex combination of multiscale objects existing in remote sensing images (RSIs), the exploration and modeling of contextual information have become the key to accurately identifying the objects at different scales. Although several methods have been proposed in the past decade, insufficient context modeling of global or local information, which easily results in the fragmentation of large-scale objects, the ignorance of small-scale objects, and blurred boundaries. To address the above issues, we propose a contextual representation enhancement network (CRENet) to strengthen the global context (GC) and local context (LC) modeling in high-level features. The core components of the CRENet are the local feature alignment enhancement module (LFAEM) and the superpixel affinity loss (SAL). The LFAEM aligns and enhances the LC in low-level features by constructing contextual contrast through multilayer cascaded deformable convolution and is then supplemented with high-level features to refine the segmentation map. The SAL assists the network to accurately capture the GC by supervising semantic information and relationship learned from superpixels. The proposed method is plug-and-play and can be embedded in any FCN-based network. Experiments on two popular RSI datasets demonstrate the effectiveness of our proposed network with competitive performance in qualitative and quantitative aspects.
Language	English
Publishing date	2024-02-29
Publishing country	United States
Document type	Journal Article
ISSN	2162-2388
ISSN (online)	2162-2388
DOI	10.1109/TNNLS.2022.3201820
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Article ; Online: CsTPS21 encodes a jasmonate-responsive monoterpene synthase producing β-ocimene in citrus against Asian citrus psyllid.

Bin, Minliang / Peng, Xinxiang / Yi, Ganjun / Zhang, Xinxin

Plant physiology and biochemistry : PPB

2023 Volume 201, Page(s) 107887

Abstract: Huanglongbing (HLB), spread by the Asian citrus psyllid (ACP), is a widespread, devastating disease that causes significant losses in citrus production. Therefore, controlling the ACP infestation and HLB infection is very important for citrus production. ...

Abstract	Huanglongbing (HLB), spread by the Asian citrus psyllid (ACP), is a widespread, devastating disease that causes significant losses in citrus production. Therefore, controlling the ACP infestation and HLB infection is very important for citrus production. The aim of our study was to identify any citrus volatile which could be used as a repellent or less attractant towards ACP, and to envisage the potential of this strategy to control HLB spread. The present study identified a terpene synthase (TPS)-encoding gene CsTPS21 in citrus plants, and this gene was predicted to encode a monoterpene synthase and had an amino acid sequence similar to β-ocimene synthase. CsTPS21 was significantly upregulated by ACP infestation and methyl jasmonic acid (MeJA) treatment but downregulated by salicylic acid (SA). Further heterologous gene expression studies in yeast cells and tobacco plants indicated that the protein catalyzed the formation of β-ocimene, which acted as an ACP repellent. Detailed analysis of tobacco overexpressing CsTPS21 showed that CsTPS21 synthesizing β-ocimene regulated jasmonic acid (JA)-associated pathways by increasing the JA accumulation and inducing the JA biosynthetic gene expression to defend against insect infestation. These findings provide a basis to plan strategies to manage HLB in the field using β-ocimene and CsTPS21 as candidates.
MeSH term(s)	Animals ; Citrus/genetics ; Citrus/metabolism ; Hemiptera ; Plant Diseases/genetics
Chemical Substances	jasmonic acid (6RI5N05OWW) ; beta-ocimene (13877-91-3) ; pinene cyclase I (EC 5.5.-)
Language	English
Publishing date	2023-07-10
Publishing country	France
Document type	Journal Article
ZDB-ID	742978-2
ISSN	1873-2690 ; 0981-9428
ISSN (online)	1873-2690
ISSN	0981-9428
DOI	10.1016/j.plaphy.2023.107887
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Article ; Online: Exploring jujube wine flavor and fermentation mechanisms by HS-SPME-GC-MS and UHPLC-MS metabolomics.

Zhao, Xinxin / Wang, Zhouping / Tang, Fengxian / Cai, Wenchao / Peng, Bo / Shan, Chunhui

Food chemistry: X

2024 Volume 21, Page(s) 101115

Abstract: The fermentation metabolites significantly influence the quality of jujube wine. However, the dynamics of these metabolites during fermentation are not well understood. In this study, a total of 107 volatile and 1758 non-volatile compounds were ... ...

Abstract	The fermentation metabolites significantly influence the quality of jujube wine. However, the dynamics of these metabolites during fermentation are not well understood. In this study, a total of 107 volatile and 1758 non-volatile compounds were identified using a flavor-directed research strategy and non-targeted metabolomics. The increase in esters and alcohols during fermentation shifted the aroma from grassy, mushroomy, and earthy to a floral and fruity flavor in the jujube wine. Leucine and phenylalanine were notably enriched during fermentation, potentially benefiting human health and enriching the flavor of fruit wines. Moreover, pathway analysis identified four key metabolic pathways and two crucial metabolic substrates, pyruvate and l-aspartate. This study provides a theoretical reference for optimizing the fermentation process and enhancing the quality of jujube wine.
Language	English
Publishing date	2024-01-03
Publishing country	Netherlands
Document type	Journal Article
ISSN	2590-1575
ISSN (online)	2590-1575
DOI	10.1016/j.fochx.2024.101115
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Article ; Online: PNP-type ligands enabled copper-catalyzed

Song, Zijie / Liu, Jun / Xing, Shuya / Shao, Xinxin / Li, Jiayun / Peng, Jiajian / Bai, Ying

Organic & biomolecular chemistry

2023 Volume 21, Issue 4, Page(s) 832–837

Abstract: The sustainable catalytic transformation of carbon dioxide into valuable fine chemicals with high efficiency is a global challenge as although ... ...

Abstract	The sustainable catalytic transformation of carbon dioxide into valuable fine chemicals with high efficiency is a global challenge as although CO
Language	English
Publishing date	2023-01-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2097583-1
ISSN	1477-0539 ; 1477-0520
ISSN (online)	1477-0539
ISSN	1477-0520
DOI	10.1039/d2ob01986h
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Article ; Online: Single Electron Transfer Reductive Deuteration of Acyl Chlorides for the Synthesis of Deuterated Alcohols with a High Deuterium Atom Economy.

Li, Hengzhao / Peng, Mengqi / Wang, Lijun / Jiang, Tingting / Li, Xinxin / Fu, Yijing / Hu, Zhaonong / An, Jie

Organic letters

2024 Volume 26, Issue 3, Page(s) 719–723

Abstract: We present a highly deuterium atom economical approach for the synthesis of deuterated alcohols via the single electron transfer (SET) reductive deuteration of acyl chlorides. Cost-effective sodium dispersion and EtOD- ...

Abstract	We present a highly deuterium atom economical approach for the synthesis of deuterated alcohols via the single electron transfer (SET) reductive deuteration of acyl chlorides. Cost-effective sodium dispersion and EtOD-
Language	English
Publishing date	2024-01-18
Publishing country	United States
Document type	Journal Article
ISSN	1523-7052
ISSN (online)	1523-7052
DOI	10.1021/acs.orglett.3c04155
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