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  1. Article ; Online: TFE3-RCC of the right kidney in an eight-year-old child.

    Wu, Yaoxing / Xie, Xiao Long / Xiang, Bo

    Asian journal of surgery

    2024  

    Language English
    Publishing date 2024-03-22
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.03.105
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2831: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Susceptibility Loci in SLC15A1, UGT1A3, and CWC27 Genes Associated with Bladder Cancer in the Northeast Chinese Population.

    Wu, Peihong / Guo, Yaoxing

    publication RETRACTED

    BioMed research international

    2022  Volume 2022, Page(s) 2988159

    Abstract: Bladder cancer (BCa) is an increasingly severe clinical and public health issue. Therefore, we aim to investigate BCa susceptibility loci in the Chinese population. In this study, 487 BCa patients and 563 controls were recruited from the First Affiliated ...

    Abstract Bladder cancer (BCa) is an increasingly severe clinical and public health issue. Therefore, we aim to investigate BCa susceptibility loci in the Chinese population. In this study, 487 BCa patients and 563 controls were recruited from the First Affiliated Hospital of China Medical University from July 2015 to September 2020. A total of ten single-nucleotide polymorphisms (SNPs) in solute carrier family 15 member 1 (SLC15A1), CWC27 spliceosome associated cyclophilin (CWC27), or UDP glucuronosyltransferase family 1 member A3 (UGT1A3) genes were genotyped. The associations between the candidate SNPs and BCa were analyzed using genotype and haplotype analysis. The results demonstrated that Rs4646227 of SLC15A1 has a significant association with BCa. The patients with CG (OR =2.513,
    MeSH term(s) Humans ; Cyclophilins/genetics ; Genetic Predisposition to Disease/genetics ; Glucuronosyltransferase/genetics ; Peptide Transporter 1/genetics ; Urinary Bladder Neoplasms/genetics
    Chemical Substances Cwc27 protein, human (EC 5.2.1.-) ; Cyclophilins (EC 5.2.1.-) ; Glucuronosyltransferase (EC 2.4.1.17) ; Peptide Transporter 1 ; SLC15A1 protein, human ; UDP-glucuronosyltransferase, UGT1A3 (EC 2.4.1.-)
    Language English
    Publishing date 2022-09-10
    Publishing country United States
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2022/2988159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: HeadDiff: Exploring Rotation Uncertainty With Diffusion Models for Head Pose Estimation.

    Wang, Yaoxing / Liu, Hao / Feng, Yaowei / Li, Zhendong / Wu, Xiangjuan / Zhu, Congcong

    IEEE transactions on image processing : a publication of the IEEE Signal Processing Society

    2024  Volume 33, Page(s) 1868–1882

    Abstract: In this paper, we propose a probabilistic regression diffusion model for head pose estimation, dubbed HeadDiff, which typically addresses the rotation uncertainty, especially when faces are captured in wild conditions. Unlike conventional image-to-pose ... ...

    Abstract In this paper, we propose a probabilistic regression diffusion model for head pose estimation, dubbed HeadDiff, which typically addresses the rotation uncertainty, especially when faces are captured in wild conditions. Unlike conventional image-to-pose methods which cannot explicitly establish the rotational manifold of head poses, our HeadDiff aims to ensure the pose rotation via the diffusion process and in parallel, refine the mapping process iteratively. Specifically, we initially formulate the head pose estimation problem as a reverse diffusion process, defining a paradigm for progressive denoising on the manifold, which explores the uncertainty by decomposing the large gap into intermediate steps. Moreover, our HeadDiff is equipped with an isotropic Gaussian distribution by encoding the incoherence information in our rotation representation. Finally, we learn the facial relationship of nearest neighbors with a cycle-consistent constraint for robust pose estimation versus diverse shape variations. Experimental results on multiple datasets demonstrate that our proposed method outperforms existing state-of-the-art techniques without auxiliary data.
    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Journal Article
    ISSN 1941-0042
    ISSN (online) 1941-0042
    DOI 10.1109/TIP.2024.3372457
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  4. Article ; Online: Refining acute human exposure assessment to pesticides in surface water: An integrated data-driven modeling approach.

    Wu, Yaoxing / Grant, Shanique / Chen, Wenlin / Szarka, Arpad

    The Science of the total environment

    2022  Volume 865, Page(s) 161190

    Abstract: The substantial spatial and temporal variability of pesticides has led to large uncertainties when determining their peak aqueous concentrations. There is however a lack of large-scale studies dealing with accurate determination of annual maximum daily ... ...

    Abstract The substantial spatial and temporal variability of pesticides has led to large uncertainties when determining their peak aqueous concentrations. There is however a lack of large-scale studies dealing with accurate determination of annual maximum daily concentration (AMDC) across the landscape and over time based on the publicly available monitoring data. We developed a novel data-driven approach that firstly used time series modeling to generate AMDCs for qualified water monitoring sites in the conterminous U.S. With feature variables such as pesticide use and land cover compiled into the dataset, machine learning models using eXtreme Gradient Boosting (XGBoost) and Random Forest Regressor (RF) were then developed to estimate AMDCs in surface waters across the U.S. Both models exhibited significant predictability, while a hybrid model consisting of the average predictions by XGBoost and RF model had the highest prediction accuracy (mean absolute error (MAE): 1.23; R
    MeSH term(s) Humans ; Pesticides/analysis ; Water/analysis ; Environmental Monitoring ; Herbicides/analysis ; Atrazine/analysis
    Chemical Substances Pesticides ; Water (059QF0KO0R) ; Herbicides ; Atrazine (QJA9M5H4IM)
    Language English
    Publishing date 2022-12-26
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2022.161190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Artificial intelligence-driven microbiome data analysis for estimation of postmortem interval and crime location.

    Wu, Ze / Guo, Yaoxing / Hayakawa, Miren / Yang, Wei / Lu, Yansong / Ma, Jingyi / Li, Linghui / Li, Chuntao / Liu, Yingchun / Niu, Jun

    Frontiers in microbiology

    2024  Volume 15, Page(s) 1334703

    Abstract: Microbial communities, demonstrating dynamic changes in cadavers and the surroundings, provide invaluable insights for forensic investigations. Conventional methodologies for microbiome sequencing data analysis face obstacles due to subjectivity and ... ...

    Abstract Microbial communities, demonstrating dynamic changes in cadavers and the surroundings, provide invaluable insights for forensic investigations. Conventional methodologies for microbiome sequencing data analysis face obstacles due to subjectivity and inefficiency. Artificial Intelligence (AI) presents an efficient and accurate tool, with the ability to autonomously process and analyze high-throughput data, and assimilate multi-omics data, encompassing metagenomics, transcriptomics, and proteomics. This facilitates accurate and efficient estimation of the postmortem interval (PMI), detection of crime location, and elucidation of microbial functionalities. This review presents an overview of microorganisms from cadavers and crime scenes, emphasizes the importance of microbiome, and summarizes the application of AI in high-throughput microbiome data processing in forensic microbiology.
    Language English
    Publishing date 2024-01-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1334703
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  6. Article ; Online: Molecular mechanisms and cellular functions of liquid-liquid phase separation during antiviral immune responses.

    Yang, Shuai / Shen, Weishan / Hu, Jiajia / Cai, Sihui / Zhang, Chenqiu / Jin, Shouheng / Guan, Xiangdong / Wu, Jianfeng / Wu, Yaoxing / Cui, Jun

    Frontiers in immunology

    2023  Volume 14, Page(s) 1162211

    Abstract: Spatiotemporal separation of cellular components is vital to ensure biochemical processes. Membrane-bound organelles such as mitochondria and nuclei play a major role in isolating intracellular components, while membraneless organelles (MLOs) are ... ...

    Abstract Spatiotemporal separation of cellular components is vital to ensure biochemical processes. Membrane-bound organelles such as mitochondria and nuclei play a major role in isolating intracellular components, while membraneless organelles (MLOs) are accumulatively uncovered
    MeSH term(s) Antiviral Agents ; Cell Nucleus ; Immunity
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2023-05-10
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1162211
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  7. Article: Selective Autophagy Regulates Innate Immunity Through Cargo Receptor Network.

    Wu, Yaoxing / Cui, Jun

    Advances in experimental medicine and biology

    2019  Volume 1209, Page(s) 145–166

    Abstract: Autophagy, an evolutionarily conserved cargo degradation process, is responsible to remove superfluous and unwanted cytoplasmic materials and maintain cellular homeostasis. Autophagy can be highly selective and target specific cargoes by utilizing ... ...

    Abstract Autophagy, an evolutionarily conserved cargo degradation process, is responsible to remove superfluous and unwanted cytoplasmic materials and maintain cellular homeostasis. Autophagy can be highly selective and target specific cargoes by utilizing multiple cargo receptors, which bind both ubiquitinated cargoes and autophagosomes. Mounting evidence has revealed the deep involvement of selective autophagy in innate immunity upon pathogen invasion, including eliminating microbial pathogens, initiating the anti-microbe responses, and inhibiting excessive immune responses. Given the importance of selective autophagy in innate immunity, how cargo receptors deliver pathogens and intracellular host constitutes to autophagosomes during infection remains to be elucidated. In this review, we summarize current evidence for the regulation of innate immunity by selective autophagy and try to elucidate the mechanisms employed by cargo receptor network in mediating diverse innate immune responses.
    MeSH term(s) Animals ; Autophagosomes ; Autophagy/immunology ; Humans ; Immunity, Innate/immunology ; Ubiquitin
    Chemical Substances Ubiquitin
    Language English
    Publishing date 2019-11-15
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-981-15-0606-2_9
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  8. Article ; Online: Echinacea purpurea (L.) Moench extract suppresses inflammation by inhibition of C3a/C3aR signaling pathway in TNBS-induced ulcerative colitis rats

    Gu, Daxing / Wang, Huiting / Yan, Mingen / Li, Yaoxing / Yang, Shijing / Shi, Dayou / Guo, Shining / Wu, Li / Liu, Cui

    Journal of Ethnopharmacology. 2023 May, v. 307 p.116221-

    2023  

    Abstract: Echinacea purpurea (L.) Moench (EP) is a perennial herbaceous flowering plant, commonly known as purple conical flower. It was widely used to treat skin inflammation and gastrointestinal diseases. Ulcerative colitis (UC) is a chronic and nonspecific ... ...

    Abstract Echinacea purpurea (L.) Moench (EP) is a perennial herbaceous flowering plant, commonly known as purple conical flower. It was widely used to treat skin inflammation and gastrointestinal diseases. Ulcerative colitis (UC) is a chronic and nonspecific inflammatory disease. Recent evidence shows that immune disorders are involved in the pathogenesis of UC. To evaluate the protective effect of Echinacea purpurea (L.) Moench exact (EE) on UC and explore the role of complement system in the treatment of UC. UC model was induced in rats by 2,4,6-trinitrobenzene sulfonic acid (TNBS), and then rats were administered with EE for 10 days. Collect colon tissues for analysis of relevant mechanisms. EE could reduce the weight loss and diarrhea of UC rats. In addition, EE could improve the integrity of intestinal epithelial barrier in UC rats. EE inhibited the level of proinflammatory cytokines and promoted the antioxidation. Furthermore, EE suppressed the expression of C3aR, CFB, CD55, TLR4 and NLRP3. These results indicate that EE may achieve therapeutic effect by inhibiting C3a/C3aR signal pathway, suggesting that EE may be used as a medicinal plant to alleviate UC.
    Keywords Echinacea purpurea ; colon ; complement ; cytokines ; diarrhea ; epithelium ; flowers ; inflammation ; medicinal plants ; models ; pathogenesis ; protective effect ; signal transduction ; sulfonic acids ; therapeutics ; traditional medicine ; ulcerative colitis ; weight loss ; Echinacea purpurea (L.) Moench ; Medicinal plant
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Use and reproduction
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2023.116221
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 90/710: Show issues

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  9. Article: Separation and Concentration of Nitrogen and Phosphorus in a Bipolar Membrane Electrodialysis System.

    Wu, Xiaoyun / Cai, Wanling / Fu, Yuying / Liu, Yaoxing / Ye, Xin / Qian, Qingrong / Van der Bruggen, Bart

    Membranes

    2022  Volume 12, Issue 11

    Abstract: Struvite crystallization is a successful technique for simultaneously recovering ... ...

    Abstract Struvite crystallization is a successful technique for simultaneously recovering PO
    Language English
    Publishing date 2022-11-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2614641-1
    ISSN 2077-0375
    ISSN 2077-0375
    DOI 10.3390/membranes12111116
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  10. Article ; Online: Echinacea purpurea (L.) Moench extract suppresses inflammation by inhibition of C3a/C3aR signaling pathway in TNBS-induced ulcerative colitis rats.

    Gu, Daxing / Wang, Huiting / Yan, Mingen / Li, Yaoxing / Yang, Shijing / Shi, Dayou / Guo, Shining / Wu, Li / Liu, Cui

    Journal of ethnopharmacology

    2023  Volume 307, Page(s) 116221

    Abstract: Ethnopharmacological relevance: Echinacea purpurea (L.) Moench (EP) is a perennial herbaceous flowering plant, commonly known as purple conical flower. It was widely used to treat skin inflammation and gastrointestinal diseases.: Aim of study: ... ...

    Abstract Ethnopharmacological relevance: Echinacea purpurea (L.) Moench (EP) is a perennial herbaceous flowering plant, commonly known as purple conical flower. It was widely used to treat skin inflammation and gastrointestinal diseases.
    Aim of study: Ulcerative colitis (UC) is a chronic and nonspecific inflammatory disease. Recent evidence shows that immune disorders are involved in the pathogenesis of UC. To evaluate the protective effect of Echinacea purpurea (L.) Moench exact (EE) on UC and explore the role of complement system in the treatment of UC.
    Materials and methods: UC model was induced in rats by 2,4,6-trinitrobenzene sulfonic acid (TNBS), and then rats were administered with EE for 10 days. Collect colon tissues for analysis of relevant mechanisms.
    Results: EE could reduce the weight loss and diarrhea of UC rats. In addition, EE could improve the integrity of intestinal epithelial barrier in UC rats. EE inhibited the level of proinflammatory cytokines and promoted the antioxidation. Furthermore, EE suppressed the expression of C3aR, CFB, CD55, TLR4 and NLRP3.
    Conclusion: These results indicate that EE may achieve therapeutic effect by inhibiting C3a/C3aR signal pathway, suggesting that EE may be used as a medicinal plant to alleviate UC.
    MeSH term(s) Animals ; Rats ; Colitis, Ulcerative/drug therapy ; Colon ; Echinacea ; Inflammation/pathology ; Signal Transduction ; Trinitrobenzenesulfonic Acid ; Complement C3a/metabolism
    Chemical Substances Trinitrobenzenesulfonic Acid (8T3HQG2ZC4) ; Complement C3a (80295-42-7) ; anaphylatoxin receptor C3a, rat
    Language English
    Publishing date 2023-02-06
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2023.116221
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1494: Show issues Location:
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