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  1. Book: Regulation of gene expression by small RNAs

    Gaur, Rajesh K.

    2009  

    Author's details ed. by Rajesh K. Gaur
    Keywords MicroRNAs / genetics ; Gene Expression Regulation
    Language English
    Size XVII, 431 S. : Ill., graph. Darst.
    Publisher CRC Press
    Publishing place Boca Raton u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015892515
    ISBN 978-0-8493-9169-9 ; 0-8493-9169-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 2187 order for loan Magazin

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  2. Article: Taxonomic Assignment-Based Genome Reconstruction from Apical Periodontal Metagenomes to Identify Antibiotic Resistance and Virulence Factors.

    Kumari, K Swapna / Dixit, Sangita / Gaur, Mahendra / Behera, Dibyajyoti Uttameswar / Dey, Suchanda / Sahoo, Rajesh Kumar / Dash, Patitapaban / Subudhi, Enketeswara

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 1

    Abstract: Primary apical periodontitis occurs due to various insults to the dental pulp including microbial infections, physical and iatrogenic trauma, whereas inadequate elimination of intraradicular infection during root canal treatment may lead to secondary ... ...

    Abstract Primary apical periodontitis occurs due to various insults to the dental pulp including microbial infections, physical and iatrogenic trauma, whereas inadequate elimination of intraradicular infection during root canal treatment may lead to secondary apical periodontitis. We explored the complex intra-radicular microbial communities and their functional potential through genome reconstruction. We applied shotgun metagenomic sequencing, binning and functional profiling to identify the significant contributors to infection at the acute and chronic apical periodontal lesions. Our analysis revealed the five classified clusters representing
    Language English
    Publishing date 2023-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13010194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Complete nucleotide sequence of a new geminivirus isolated from

    Marwal, Avinash / Kumar, Rajesh / Paul Khurana, S M / Gaur, R K

    Virusdisease

    2018  Volume 30, Issue 1, Page(s) 106–111

    Abstract: Symptomless grape plants ( ...

    Abstract Symptomless grape plants (
    Language English
    Publishing date 2018-07-17
    Publishing country India
    Document type Journal Article
    ZDB-ID 2846993-8
    ISSN 2347-3517 ; 2347-3584
    ISSN (online) 2347-3517
    ISSN 2347-3584
    DOI 10.1007/s13337-018-0477-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Interference of bio-control Trichoderma to enhance physical and physiological strength of sugarcane during Pokkah boeng infection.

    Tiwari, Raghvendra / Chandra, Kajal / Shukla, S K / Jaiswal, V P / Amaresan, Natarajan / Srivastava, Abhay Kumar / Gaur, Asha / Sahni, Divya / Tiwari, Rajesh Kumar

    World journal of microbiology & biotechnology

    2022  Volume 38, Issue 8, Page(s) 139

    Abstract: Tremendous benefits have been derived from the use of fungicides but excessive use of chemical fungicides not only posing threat to human and animal life but also contaminates the prevailing environment. Damage by pathogenic fungi alone causes ... ...

    Abstract Tremendous benefits have been derived from the use of fungicides but excessive use of chemical fungicides not only posing threat to human and animal life but also contaminates the prevailing environment. Damage by pathogenic fungi alone causes significant damage to crops like maize, rice, wheat, soybeans, and potatoes. Therefore, it becomes imperative that these diseases are checked and controlled, for which chemical pesticides are being sprayed on plants extensively. Considering the devastating damage and toxicity, the global focus has taken a drift from synthetic chemicals to nature-friendly biological control agents. The present study focuses on the use of biological control agents particularly Trichoderma in sugarcane during Pokkah boeng infection. In the present experiment, twenty promising Trichoderma strains were evaluated for plant growth promotion, lytic enzymes, and physiological and biocontrol activity. Out of the twenty, four potential Trichoderma strains were assessed in the pot experiment viz. T. harzianum strain T28, T41 and T49 and T. aureoviride strain T38. The T. harzianum (T28) showed efficient plant growth-promoting traits as it produced IAA (20.67 µg/ml), phosphorus solubilization (18.57 µg/ml), and cell wall degrading enzymes such as chitinase (24.98 µg/ml) and β-glucanase (29.98 µg/ml). The interference of biocontrol agent T. harzianum (T28) controlled the disease by 73.55%. Apart from this, the inoculation of Trichoderma (T28) enhanced growth attributes including germination percentage (26.61%), mean tiller number (8.28 tiller/pot), individual cane length (241.5 cm), single cane weight (1.13 kg) and the number of milleable canes (6.00 cane/pot). Improvements in physiological activities at different growth stages of the sugarcane crop were observed based on the photosynthetically active radiation (PAR) on the leaf surface, transpiration rate, stomatal conductance, and photosynthetic rate. Further, improvement in juice quality parameters was also observed as it recorded the highest
    MeSH term(s) Biological Control Agents/pharmacology ; Chitinases ; Fungicides, Industrial ; Plant Diseases/microbiology ; Plant Diseases/prevention & control ; Saccharum/microbiology ; Trichoderma
    Chemical Substances Biological Control Agents ; Fungicides, Industrial ; Chitinases (EC 3.2.1.14)
    Language English
    Publishing date 2022-06-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1499109-3
    ISSN 1573-0972 ; 0959-3993
    ISSN (online) 1573-0972
    ISSN 0959-3993
    DOI 10.1007/s11274-022-03319-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Establishment and multiparametric-cytogenetic validation of

    Chaurasia, Rajesh Kumar / Bhat, N N / Gaur, Neeraj / Shirsath, K B / Desai, U N / Sapra, B K

    Mutation research. Genetic toxicology and environmental mutagenesis

    2021  Volume 866, Page(s) 503354

    Abstract: Exposure to ionizing radiation is unavoidable to our modern developing society as its applications are widespread and increasing with societal development. The exposures may be planned as in medical applications or may be unplanned as in occupational ... ...

    Abstract Exposure to ionizing radiation is unavoidable to our modern developing society as its applications are widespread and increasing with societal development. The exposures may be planned as in medical applications or may be unplanned as in occupational work and radiological emergencies. Dose quantification of planned and unplanned exposures is essential to make crucial decisions for management of such exposures. This study aims to establish ex-vivo dose-response curve for
    MeSH term(s) Calibration ; Cobalt Radioisotopes/administration & dosage ; Cobalt Radioisotopes/toxicity ; Cytogenetic Analysis/methods ; Cytogenetics/methods ; Dose-Response Relationship, Radiation ; Emergencies ; Gamma Rays/adverse effects ; Histones/metabolism ; Humans ; Lymphocytes/metabolism ; Lymphocytes/radiation effects ; Radiation, Ionizing ; Triage/methods
    Chemical Substances Cobalt Radioisotopes ; Histones ; Cobalt-60 (5C8182XDPZ)
    Language English
    Publishing date 2021-04-02
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1879-3592
    ISSN (online) 1879-3592
    DOI 10.1016/j.mrgentox.2021.503354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A comprehensive review on potential therapeutics interventions for COVID-19.

    Chugh, Heerak / Awasthi, Amardeep / Agarwal, Yashi / Gaur, Rajesh K / Dhawan, Gagan / Chandra, Ramesh

    European journal of pharmacology

    2020  Volume 890, Page(s) 173741

    Abstract: COVID-19 is an infectious respiratory disease caused by SARS-CoV-2, a new beta coronavirus that emerged in Wuhan, China. Being primarily a respiratory disease, it is highly transmissible through both direct and indirect contacts. It displays a range of ... ...

    Abstract COVID-19 is an infectious respiratory disease caused by SARS-CoV-2, a new beta coronavirus that emerged in Wuhan, China. Being primarily a respiratory disease, it is highly transmissible through both direct and indirect contacts. It displays a range of symptoms in different individuals and thus has been grouped into mild, moderate, and severe diseases. The virus utilizes spike proteins present on its surface to recognize ACE-2 receptors present on the host cells to enter the cell cytoplasm and replicate. The viral invasion of cells induces damage response, pyroptosis, infiltration of immune cells, expression of pro-inflammatory cytokines (cytokine storm), and activation of the adaptive immune system. Depending on viral load and host factors like age and underlying medical conditions, the immune responses mounted against SARS-CoV-2 may cause acute respiratory distress syndrome (ARDS), multiple organ failure, and death. In this review, we specify and justify both viral and host therapeutic targets that can be modulated to relieve the symptoms and treat the disease. Furthermore, we discuss vaccine development in the time of pandemic and the most promising vaccine candidates by far, according to WHO database. Finally, we discuss the conventional re-purposed drugs and potential alternative treatments as adjuvants.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Animals ; Antiviral Agents/therapeutic use ; COVID-19/epidemiology ; COVID-19/therapy ; Drug Repositioning ; Epidemics ; Humans ; Immunization, Passive ; Medicine, Ayurvedic ; Medicine, Chinese Traditional ; SARS-CoV-2/immunology ; Viral Vaccines ; COVID-19 Drug Treatment ; COVID-19 Serotherapy
    Chemical Substances Adrenal Cortex Hormones ; Antiviral Agents ; Viral Vaccines
    Language English
    Publishing date 2020-11-20
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 80121-5
    ISSN 1879-0712 ; 0014-2999
    ISSN (online) 1879-0712
    ISSN 0014-2999
    DOI 10.1016/j.ejphar.2020.173741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 522: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Identification and molecular characterization of Dof transcription factor gene family preferentially expressed in developing spikes of

    Gupta, Supriya / Pathak, Rajesh Kumar / Gupta, Sanjay Mohan / Gaur, Vikram Singh / Singh, N K / Kumar, Anil

    3 Biotech

    2018  Volume 8, Issue 2, Page(s) 82

    Abstract: We report 48 putative DNA binding with one finger ( ...

    Abstract We report 48 putative DNA binding with one finger (
    Language English
    Publishing date 2018-01-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2600522-0
    ISSN 2190-5738 ; 2190-572X
    ISSN (online) 2190-5738
    ISSN 2190-572X
    DOI 10.1007/s13205-017-1068-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Achievements and prospects of genetic engineering in poplar: a review

    Thakur, Ajay K. / Kumar, Pankaj / Parmar, Nehanjali / Shandil, Rajesh K. / Aggarwal, Gaurav / Gaur, Ayesh / Srivastava, Dinesh K.

    New forests. 2021 Nov., v. 52, no. 6

    2021  

    Abstract: Poplars play important role in global forestry. Besides being cultivated as an agro-forestry crop, they provide mankind with fuel wood, timber wood, plywood, sports goods, raw material for paper industry and recently, they are being used as a potential ... ...

    Abstract Poplars play important role in global forestry. Besides being cultivated as an agro-forestry crop, they provide mankind with fuel wood, timber wood, plywood, sports goods, raw material for paper industry and recently, they are being used as a potential biofuel source. However, a number of biotic and abiotic stresses reduce poplar yield and productivity. Further, there is a strong felt need of paper and pulp industries to have reduced lignin content or modified lignin composition of poplar wood, which will assist in manufacturing better quality paper using less environmentally hazardous chemicals. Because of the non-availability of resistance donor sources and long generation period, conventional breeding could achieve success in genetic improvement of poplars. To circumvent these bottlenecks, genetic engineering interventions have been applied for poplar crop improvement. With the availability of Populus trichocarpa genome sequence in public domain, now numerous genes and transcription factors governing various metabolic pathways got identified, which can be targeted for genetic engineering for poplar improvement. Genome editing technology has really expedited the pace of poplar improvement programmes. This review provides an insight into various research efforts focused on poplar genetic engineering for improvement of silviculturally important traits.
    Keywords Populus trichocarpa ; agroforestry ; biofuels ; fuelwood ; genetic improvement ; humans ; lignin ; lignin content ; nucleotide sequences ; paper ; plywood ; pulp and paper industry ; raw materials
    Language English
    Dates of publication 2021-11
    Size p. 889-920.
    Publishing place Springer Netherlands
    Document type Article
    Note Review
    ZDB-ID 1038718-3
    ISSN 0169-4286
    ISSN 0169-4286
    DOI 10.1007/s11056-021-09836-3
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 5824: Show issues

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  9. Article: Complete nucleotide sequence of a new geminivirus isolated from Vitis vinifera in India: a symptomless host of Grapevine red blotch virus

    Avinash, M. l / Rajesh, K. r / Khurana, S. M. P. / Gaur, R. K.

    VirusDisease

    2019  Volume 30, Issue 1, Page(s) 106–111

    Abstract: Vitis vinifera; geminivirus; GRBV; India. ...

    Institution Department of Biosciences, College of Arts, Science and Humanities, Mody University of Science and Technology, 332 311 Lakshmangarh, Sikar, Rajasthan, India
    Abstract Vitis vinifera; geminivirus; GRBV; India.
    Language English
    Document type Article
    DOI 10.1007/s13337-018-0477-x
    Database Viticulture and Oenology Abstracts

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  10. Article: T7 RNA polymerase-mediated incorporation of 8-N(3)AMP into RNA for studying protein-RNA interactions.

    Gaur, Rajesh K

    Methods in molecular biology (Clifton, N.J.)

    2008  Volume 488, Page(s) 167–180

    Abstract: Ultraviolet (UV)-dependent photochemical crosslinking is a powerful approach that can be used for the identification of RNA-protein interactions. Although 8-azidoATP (8-N(3)ATP) has been widely used to elucidate the ATP binding site of a variety of ... ...

    Abstract Ultraviolet (UV)-dependent photochemical crosslinking is a powerful approach that can be used for the identification of RNA-protein interactions. Although 8-azidoATP (8-N(3)ATP) has been widely used to elucidate the ATP binding site of a variety of proteins, its inability to serve as an efficient substrate for bacteriophage RNA polymerases apparently restricted its actual potential as a photocrosslinking agent. In this chapter, in vitro transcription conditions that allow for template-dependent incorporation of 8-N(3)AMP into RNA are described. In addition, it is shown that a high-affinity MS2 coat protein binding sequence, in which adenosine residues were replaced by 8-azidoadenosine, crosslinks to the coat protein of the Escherichia coli phage MS2. This approach can be extended to identify almost any RNA binding protein.
    MeSH term(s) Adenosine Monophosphate/analogs & derivatives ; Adenosine Monophosphate/chemistry ; Adenosine Monophosphate/metabolism ; Cross-Linking Reagents/chemistry ; DNA-Directed RNA Polymerases/metabolism ; Protein Binding/radiation effects ; Proteins/chemistry ; Proteins/metabolism ; RNA/chemistry ; RNA/metabolism ; Ultraviolet Rays ; Viral Proteins/metabolism
    Chemical Substances Cross-Linking Reagents ; Proteins ; Viral Proteins ; Adenosine Monophosphate (415SHH325A) ; RNA (63231-63-0) ; bacteriophage T7 RNA polymerase (EC 2.7.7.-) ; DNA-Directed RNA Polymerases (EC 2.7.7.6)
    Language English
    Publishing date 2008
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1064-3745
    ISSN 1064-3745
    DOI 10.1007/978-1-60327-475-3_11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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