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  1. Article: Partial Characterization and Natural Antioxidant Activity of Law sonia inermis L.

    Sharma, Preeti / Kaushik, Vikas / Battan, Bindu / Sindhu, Anil

    Annals of biology

    2020  Volume 36, Issue 3, Page(s) 372

    Document type Article
    ZDB-ID 15373-4
    ISSN 0970-0153
    Database Current Contents Nutrition, Environment, Agriculture

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  2. Book: Oral delivery of insulin

    Sonia Thundiparambil Azeez / Sharma, Chandra P.

    (Woodhead Publishing series in biomedicine ; 41)

    2014  

    Author's details Thundiparambil Azeez Sonia and Chandra P. Sharma
    Series title Woodhead Publishing series in biomedicine ; 41
    Collection
    Language English
    Size XIV, 345 S. : Ill., graph. Darst.
    Publisher Elsevier Woodhead Publ
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT017566761
    ISBN 978-1-907568-47-3 ; 9781908818683 ; 1-907568-47-6 ; 1908818689
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Recent Approaches on Molecular Markers, Treatment and Novel Drug Delivery System Used for the Management of Colorectal Cancer: A Comprehensive Review.

    Chauhan, Sonia / Sharma, Sakshi

    Current pharmaceutical biotechnology

    2024  

    Abstract: Colorectal cancer affects 1 in 25 females and 1 in 24 males, making it the third most frequent cancer with over 6,08,030 deaths worldwide, despite advancements in detection and treatments, including surgery, chemotherapeutics, radiotherapy, and immune ... ...

    Abstract Colorectal cancer affects 1 in 25 females and 1 in 24 males, making it the third most frequent cancer with over 6,08,030 deaths worldwide, despite advancements in detection and treatments, including surgery, chemotherapeutics, radiotherapy, and immune therapeutics. Novel potential agents have increased survival in acute and chronic disease conditions, with a higher risk of side effects and cost. However, metastatic disease has an insignificant long-term diagnosis, and significant challenges remain due to last-stage diagnosis and treatment failure. Early detection, survival, and treatment efficacy are all improved by biomarkers. The advancement of cancer biomarkers' molecular pathology and genomics during the last three decades has improved therapy. Clinically useful prognostic biomarkers assist clinical judgment, for example, by predicting the success of EGFR-inhibiting antibodies in the presence of KRAS gene mutations. Few biomarkers are currently used in clinical settings, so further research is still needed. Nanocarriers, with materials like Carbon nanotubes and gold nanoparticles, provide targeted CRC drug delivery and diagnostics. Light-responsive drugs with gold and silica nanoparticles effectively target and destroy CRC cells. We evaluate the potential use of the long non-coding RNA (non-coding RNA) oncogene plasmacytoma variant translocation 1 (PVT1) as a diagnostic, prognostic, and therapeutic biomarker, along with the latest nanotech breakthroughs in CRC diagnosis and treatment.
    Language English
    Publishing date 2024-01-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2132197-8
    ISSN 1873-4316 ; 1389-2010
    ISSN (online) 1873-4316
    ISSN 1389-2010
    DOI 10.2174/0113892010270975231208113157
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Potential Impact of Bioactive Compounds as NLRP3 Inflammasome Inhibitors: An Update.

    Singh, Sonia / Sharma, Shiwangi / Sharma, Himanshu

    Current pharmaceutical biotechnology

    2024  

    Abstract: The inflammasome NLRP3 comprises a caspase recruitment domain, a pyrin domain containing receptor 3, an apoptosis-linked protein like a speck containing a procaspase-1, and an attached nucleotide domain leucine abundant repeat. There are a wide variety ... ...

    Abstract The inflammasome NLRP3 comprises a caspase recruitment domain, a pyrin domain containing receptor 3, an apoptosis-linked protein like a speck containing a procaspase-1, and an attached nucleotide domain leucine abundant repeat. There are a wide variety of stimuli that can activate the inflammasome NLRP3. When activated, the protein NLRP3 appoints the adapter protein ASC. Adapter ASC protein then recruits the procaspase-1 protein, which causes the procaspase- 1 protein to be cleaved and activated, which induces cytokines. At the same time, abnormal activation of inflammasome NLRP3 is associated with many diseases, such as diabetes, atherosclerosis, metabolic syndrome, cardiovascular and neurodegenerative diseases. As a result, a significant amount of effort has been put into comprehending the mechanisms behind its activation and looking for their specific inhibitors. In this review, we primarily focused on phytochemicals that inhibit the inflammasome NLRP3, as well as discuss the defects caused by NLRP3 signaling. We conducted an in-depth research review by searching for relevant articles in the Scopus, Google Scholar, and PubMed databases. By gathering information on phytochemical inhibitors that block NLRP3 inflammasome activation, a complicated balance between inflammasome activation or inhibition with NLRP3 as a key role was revealed in NLRP3-driven clinical situations.
    Language English
    Publishing date 2024-01-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2132197-8
    ISSN 1873-4316 ; 1389-2010
    ISSN (online) 1873-4316
    ISSN 1389-2010
    DOI 10.2174/0113892010276859231125165251
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Emerging Applications of Nanotechnology in Drug Delivery and Medical Imaging: Review.

    Singh, Sonia / Sharma, Himanshu

    Current radiopharmaceuticals

    2023  Volume 16, Issue 4, Page(s) 269–283

    Abstract: The use of the one-of-a-kind qualities possessed by substances at the nanoscale is the core concept of nanotechnology. Nanotechnology has become increasingly popular in various business sectors because it enables better construction and more advanced ... ...

    Abstract The use of the one-of-a-kind qualities possessed by substances at the nanoscale is the core concept of nanotechnology. Nanotechnology has become increasingly popular in various business sectors because it enables better construction and more advanced product design. Nanomedicine is the name given to the application of nanotechnology in the medical and healthcare fields. It has been used to fight against some of the most prevalent diseases, such as cancer and cardiovascular diseases. This current manuscript provides an overview of the recent advancements in nanotechnology in drug delivery and imaging.
    MeSH term(s) Humans ; Drug Delivery Systems/methods ; Nanomedicine/methods ; Nanoparticles ; Nanotechnology/methods ; Neoplasms/diagnostic imaging ; Neoplasms/drug therapy ; Radiopharmaceuticals/therapeutic use
    Chemical Substances Radiopharmaceuticals
    Language English
    Publishing date 2023-06-21
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ISSN 1874-4729
    ISSN (online) 1874-4729
    DOI 10.2174/1874471016666230621120453
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Accelerating the understanding of

    Thakur, Raman / Shishodia, Sonia Kumari / Sharma, Ananya / Chauhan, Arjun / Kaur, Sumanpreet / Shankar, Jata

    Current research in microbial sciences

    2024  Volume 6, Page(s) 100220

    Abstract: ... ...

    Abstract Aspergillus
    Language English
    Publishing date 2024-01-11
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2666-5174
    ISSN (online) 2666-5174
    DOI 10.1016/j.crmicr.2024.100220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Isolation of quinic acid from dropped

    Heena / Kaushal, Sonia / Kaur, Vishaldeep / Panwar, Harsh / Sharma, Purshotam / Jangra, Raman

    Frontiers in chemistry

    2024  Volume 12, Page(s) 1372560

    Abstract: ... Citrus ... ...

    Abstract Citrus reticulata
    Language English
    Publishing date 2024-04-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2024.1372560
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Failure to Thrive, Jaundice, and Polyuria in Early Infancy: Common Presentation with an Uncommon Lethal Etiology.

    Sharma, Sonia

    Journal of pediatric genetics

    2019  Volume 9, Issue 3, Page(s) 183–185

    Abstract: A 5-month-old female infant from a consanguineous Indian Muslim family presented with polyuria, polydipsia, failure to thrive, impaired renal function, and neonatal hepatitis of unknown cause at 1 month of age. Clinical exome testing revealed renal- ... ...

    Abstract A 5-month-old female infant from a consanguineous Indian Muslim family presented with polyuria, polydipsia, failure to thrive, impaired renal function, and neonatal hepatitis of unknown cause at 1 month of age. Clinical exome testing revealed renal-hepatic-pancreatic dysplasia caused by homozygous c. 1985 + 5G > A pathogenic variations in
    Language English
    Publishing date 2019-11-11
    Publishing country Germany
    Document type Case Reports
    ISSN 2146-4596
    ISSN 2146-4596
    DOI 10.1055/s-0039-1700802
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Exploring the therapeutic potential and bioactive compounds in Pyrus species

    Sonia Singh / Riya Verma / Himanshu Sharma

    Pharmacological Research - Modern Chinese Medicine, Vol 10, Iss , Pp 100342- (2024)

    1481  

    Abstract: Introduction: The genus Pyrus encompasses a diverse range of species the Chinese pear (Pyrus ussuriensis; Pyrus bretschneideri), Japanese pear (Pyrus pyrifolia), and the European pear (Pyrus communis) that have been extensively studied for their ... ...

    Abstract Introduction: The genus Pyrus encompasses a diverse range of species the Chinese pear (Pyrus ussuriensis; Pyrus bretschneideri), Japanese pear (Pyrus pyrifolia), and the European pear (Pyrus communis) that have been extensively studied for their phytochemical constituents and associated pharmacological activities. Materials and Methods: This manuscript provides significant data regarding the phytochemistry and pharmacological impact of many species of Pyrus. The data was gathered from electronic repositories that included Science Direct, Web of Science, Scopus, and PubMed. Result and Conclusion: This review aims to provide a comprehensive overview of the bioactive compounds present in Pyrus species and their potential therapeutic applications. The phytoconstituents identified in Pyrus plants include a variety of phenolic compounds, flavonoids, triterpenoids, and organic acids. These phytochemicals contribute to the diverse pharmacological properties exhibited by Pyrus species, such as anti-inflammatory, antimicrobial, antioxidant, antibacterial, hepatoprotective and anticancer activities.
    Keywords Pyrus ; Antioxidant ; Pear ; Flavonoids ; Antioxidants ; Other systems of medicine ; RZ201-999 ; Therapeutics. Pharmacology ; RM1-950
    Subject code 590
    Language English
    Publishing date 2024-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Acute Urinary Retention Associated with Olanzapine Long-acting Injection: A Case Report.

    Kurariya, Astut / Purohith, Abhiram N / Shenoy, Sonia / Bhandary, Rajeshkrishna P / Sharma, Podila Satya Venkata Narasimha

    Indian journal of psychological medicine

    2024  Volume 46, Issue 3, Page(s) 279–280

    Language English
    Publishing date 2024-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2622378-8
    ISSN 0975-1564 ; 0253-7176
    ISSN (online) 0975-1564
    ISSN 0253-7176
    DOI 10.1177/02537176231222566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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