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  1. Article ; Online: Editorial

    Katherine M. Warpeha / Shu Hui Chen / Catherine Mullié

    Frontiers in Public Health, Vol

    Emerging Infectious and Vector-Borne Diseases: A Global Challenge, Volume II

    2022  Volume 10

    Keywords infectious disease ; vector-borne ; zoonotic ; viral ; containment ; preparedness ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Editorial: Emerging Infectious and Vector-Borne Diseases: A Global Challenge, Volume II.

    Warpeha, Katherine M / Chen, Shu Hui / Mullié, Catherine

    Frontiers in public health

    2022  Volume 10, Page(s) 942950

    MeSH term(s) Animals ; Communicable Diseases/epidemiology ; Disease Vectors ; Vector Borne Diseases
    Language English
    Publishing date 2022-05-31
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.942950
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Editorial

    Katherine M. Warpeha / Vincent Munster / Catherine Mullié / Shu Hui Chen

    Frontiers in Public Health, Vol

    Emerging Infectious and Vector-Borne Diseases: A Global Challenge

    2020  Volume 8

    Keywords infectious disease ; vector-borne ; zoonotic ; viral ; containment ; diagnostics ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Editorial: Emerging Infectious and Vector-Borne Diseases: A Global Challenge.

    Warpeha, Katherine M / Munster, Vincent / Mullié, Catherine / Chen, Shu Hui

    Frontiers in public health

    2020  Volume 8, Page(s) 214

    MeSH term(s) Animals ; Communicable Diseases/epidemiology ; Disease Vectors ; Humans ; Vector Borne Diseases
    Keywords covid19
    Language English
    Publishing date 2020-07-07
    Publishing country Switzerland
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2020.00214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Utility of Human

    Creager, Hannah M / Kieran, Troy J / Zeng, Hui / Sun, Xiangjie / Pulit-Penaloza, Joanna A / Holmes, Katie E / Johnson, Anders F / Tumpey, Terrence M / Maines, Taronna R / Beauchemin, Catherine A A / Belser, Jessica A

    Journal of virology

    2023  Volume 97, Issue 1, Page(s) e0153622

    Abstract: As influenza A viruses (IAV) continue to cross species barriers and cause human infection, the establishment of risk assessment rubrics has improved pandemic preparedness efforts. ...

    Abstract As influenza A viruses (IAV) continue to cross species barriers and cause human infection, the establishment of risk assessment rubrics has improved pandemic preparedness efforts.
    MeSH term(s) Animals ; Humans ; Ferrets ; Influenza A virus/pathogenicity ; Influenza, Human ; Orthomyxoviridae Infections/pathology ; Risk Assessment/methods ; Swine ; Virus Replication ; Cell Line ; In Vitro Techniques
    Language English
    Publishing date 2023-01-05
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 80174-4
    ISSN 1098-5514 ; 0022-538X
    ISSN (online) 1098-5514
    ISSN 0022-538X
    DOI 10.1128/jvi.01536-22
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    Zs.A 609: Show issues Location:
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  6. Article ; Online: Urogenital urobiome of healthy children does not differ from that of children with bladder and bowel dysfunction.

    Cole, Elisabeth B / Khemmani, Mark / Liu, Hui / Halverson, Thomas M / Noronha, Melline Fontes / Forster, Catherine S / Wolfe, Alan J / Shaikh, Nader

    Journal of pediatric urology

    2023  Volume 19, Issue 4, Page(s) 368.e1–368.e8

    Abstract: Introduction: The pediatric urinary microbiome (urobiome) has been studied in the context of healthy children and children with genitourinary pathologies including neuropathic bladder, urinary tract infection (UTI) and nephrolithiasis. Little is known ... ...

    Abstract Introduction: The pediatric urinary microbiome (urobiome) has been studied in the context of healthy children and children with genitourinary pathologies including neuropathic bladder, urinary tract infection (UTI) and nephrolithiasis. Little is known about the urobiome of children with bladder and bowel dysfunction (BBD), a condition that is an established risk factor of UTI. We hypothesized that the symptoms of a child with BBD may be related to urobiome composition.
    Objective: To evaluate the urogenital urobiome's role in BBD, we compared the urogenital urobiomes of children with and without BBD.
    Study design: We performed a prospective case-control pilot study at a single large, academic children's hospital. Cases included toilet trained prepubertal females over 2 years of age with BBD established through a validated scoring system and controls included asymptomatic, presumably healthy, children. Children were excluded if they had symptoms or lab work consistent with a concurrent UTI or antibiotic course for any reason within the prior 14 days. We performed 16 S ribosomal RNA gene sequencing and expanded quantitative urine culture on clean catch urine samples. To compare within sample (alpha) diversity, we used the Kruskal-Wallis test. To compare between sample (beta) diversity, we calculated the Bray-Curtis distance and performed the PERMANOVA test.
    Results: Data from 25 children with BBD and 8 asymptomatic controls were analyzed. The demographic and clinical characteristics of the two comparison groups were similar, though a higher proportion of Black children were included in the asymptomatic control group. Neither alpha diversity nor beta diversity was significantly different between the two groups. The core microbiome of the BBD group included all the genera in the core urogenital urobiome of the controls, plus additional genera associated with opportunistic infection and/or UTI, including Escherichia, Campylobacter and Streptococcus.
    Discussion: The results of both the 16 S sequencing and expanded quantitative urine culture in this small study suggest that the urogenital urobiomes of children with BBD do not differ significantly from those of asymptomatic children. However, the core urogenital urobiome of children with BBD included genera associated with opportunistic infection and/or UTI. This study was limited by the sample collection method ("clean catch" midstream voided urine samples, which introduce the possibility of vulvovaginal contamination), small sample size, and unequal balance of patient characteristics between the two study groups.
    Conclusion: The urogenital urobiomes of children with and without BBD do not appear to significantly differ. Larger studies are needed to confirm these findings.
    MeSH term(s) Female ; Child ; Humans ; Urinary Bladder ; Pilot Projects ; Urinary Tract Infections/diagnosis ; Intestinal Diseases ; Intestines
    Language English
    Publishing date 2023-04-13
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2023.04.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6387: Show issues Location:
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  7. Article ; Online: Exercise-induced Pulmonary Hypertension in Long-term Survivors of Congenital Diaphragmatic Hernia.

    Critser, Paul J / Buchmiller, Terry L / Gauvreau, Kimberlee / Zalieckas, Jill M / Sheils, Catherine A / Visner, Gary A / Shafer, Keri M / Chen, Ming Hui / Mullen, Mary P

    The Journal of pediatrics

    2024  , Page(s) 114034

    Abstract: Objective: To determine the prevalence of exercise-induced pulmonary hypertension (PH) among long-survivors of congenital diaphragmatic hernia (CDH) repair.: Study design: This is a single-center, retrospective cohort study of CDH survivors who ... ...

    Abstract Objective: To determine the prevalence of exercise-induced pulmonary hypertension (PH) among long-survivors of congenital diaphragmatic hernia (CDH) repair.
    Study design: This is a single-center, retrospective cohort study of CDH survivors who underwent exercise stress echocardiography (ESE) at Boston Children's Hospital from January 2006 to June 2020. PH severity was assessed by echocardiogram at baseline and after exercise. Patients were categorized by right ventricular systolic pressure (RVSP) after exercise: Group 1 - no or mild PH; and Group 2 - moderate or severe PH (RVSP ≥ 60 mmHg or ≥ ½ systemic blood pressure).
    Results: Eighty-four patients with CDH underwent 173 ESE with median age 8.1 (4.8 - 19.1) years at first ESE. Sixty-four patients were classified as Group 1, 11 as Group 2, and 9 had indeterminate RVSP with ESE. Moderate to severe PH after exercise was found in 8 (10%) patients with no or mild PH at rest. Exercise-induced PH was associated with larger CDH defect size, patch repair, use of ECMO, supplemental oxygen at discharge, and higher WHO functional class. Higher VE/VCO2 slope, lower peak oxygen saturation, and lower percent predicted FEV1 and FEV1/FVC ratio were associated with Group 2 classification. ESE changed management in 9/11 Group 2 patients. PH was confirmed in all 5 Group 2 patients undergoing cardiac catheterization after ESE.
    Conclusions: Among long-term CDH survivors, 10% had moderate-severe exercise-induced PH on ESE, indicating ongoing pulmonary vascular abnormalities. Further studies are needed to optimally define PH screening and treatment for patients with repaired CDH.
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2024.114034
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  8. Article ; Online: Moderate-to-vigorous physical activity and sedentary behavior in children with and without developmental coordination disorder: Associations with fundamental movement skills.

    Yu, Jane Jie / Capio, Catherine M / Abernethy, Bruce / Sit, Cindy Hui Ping

    Research in developmental disabilities

    2021  Volume 118, Page(s) 104070

    Abstract: Background: There is a pandemic of physical inactivity in children. Compared to children with typical development (TD), those with developmental coordination disorder (DCD) are less physically active. Mastery of movement skills such as fundamental ... ...

    Abstract Background: There is a pandemic of physical inactivity in children. Compared to children with typical development (TD), those with developmental coordination disorder (DCD) are less physically active. Mastery of movement skills such as fundamental movement skills (FMS) are potential correlates of physical activity.
    Aims: To examine the associations of FMS with moderate-to-vigorous physical activity (MVPA) and sedentary behavior (SB) in children with DCD and TD.
    Methods and procedures: This cross-sectional study included 172 children with DCD (n = 73; boys = 49) or TD (n = 99; boys = 48) aged 6-10 years. Five components of FMS (running, jumping, throwing, catching, kicking) were assessed using process- and product- oriented approaches using the Test of Gross Motor Development-second edition. The time spent in MVPA and SB was measured using accelerometers.
    Outcomes and results: Children with DCD had significantly poorer performance in FMS proficiency in terms of specific movement patterns (jumping and catching) and outcomes (running, jumping, catching, and kicking) when compared to children with TD. MVPA and SB were significantly associated with certain process-oriented FMS assessments in children, which was moderated by motor coordination status and sex. Movement patterns of catching (odds ratio = 1.686, p < .05) was a significant predictor of children's attainment of the MVPA guideline.
    Conclusions and implications: It is important to develop FMS patterns and ball skills in early childhood, particularly for children with DCD, to combat physical inactivity and its related health problems.
    MeSH term(s) Child ; Child, Preschool ; Cross-Sectional Studies ; Exercise ; Humans ; Male ; Motor Skills ; Motor Skills Disorders ; Movement ; Sedentary Behavior
    Language English
    Publishing date 2021-08-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639175-8
    ISSN 1873-3379 ; 0891-4222
    ISSN (online) 1873-3379
    ISSN 0891-4222
    DOI 10.1016/j.ridd.2021.104070
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    Zs.B 2592: Show issues Location:
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  9. Article ; Online: T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice

    Florian Wiede / Benjamin J. Shields / Sock Hui Chew Konstantinos Kyparissoudis / Catherine van Vliet / Sandra Galic / Michel L. Tremblay / Sarah M. Russell / Dale I. Godfrey / Tony Tiganis

    The Journal of Clinical Investigation, Vol 133, Iss

    2023  Volume 20

    Keywords Medicine ; R
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher American Society for Clinical Investigation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Biomechanical Strength of All-Inside ACL Reconstruction Grafts Using Side-to-Side and Backup Fixation.

    Graf-Alexiou, Lucas / Karpyshyn, Jillian / Baptiste, Jonelle Jn / Hui, Catherine / Sommerfeldt, Mark / Westover, Lindsey

    Orthopaedic journal of sports medicine

    2021  Volume 9, Issue 5, Page(s) 23259671211006521

    Abstract: ... configuration: side-to-side fixation with a backup fixation at the button loop (graft M). The test configuration ... Results: Graft A had a significantly lower failure load (637 ± 99 N) compared with graft M (883 ± 66 N ...

    Abstract Background: The all-inside anterior cruciate ligament reconstruction (ACLR) procedure uses a single hamstring tendon folded twice and secured to itself to form a 4-stranded graft. There are several possible configurations for preparing the graft.
    Purpose: To investigate the biomechanical properties of a new graft preparation technique in comparison with 2 commonly used configurations.
    Study design: Controlled laboratory study.
    Methods: Five porcine flexor tendons were prepared into the test graft configuration: side-to-side fixation with a backup fixation at the button loop (graft M). The test configuration was compared with the results of a previous study that included grafts with simple interrupted sutures (graft A; n = 5) and end-to-end fixation (graft C; n = 5). All grafts were subjected to the same mechanical testing protocol to determine the mean failure load, stiffness, rate of elongation, and total elongation during both cyclic loading and pull to failure. Differences between groups were evaluated.
    Results: Graft A had a significantly lower failure load (637 ± 99 N) compared with graft M (883 ± 66 N;
    Conclusion: The new side-to-side configuration was not biomechanically superior to the end-to-end configuration; however, they were both stronger than unsecured fixation.
    Clinical relevance: As the all-inside ACLR is gaining popularity, this study provides surgeons with a new method of preparing grafts and evaluates the method with respect to currently used configurations.
    Language English
    Publishing date 2021-05-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2706251-X
    ISSN 2325-9671
    ISSN 2325-9671
    DOI 10.1177/23259671211006521
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