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  1. Article ; Online: Clinical studies and research integrity.

    Mathiesen, Tiit

    Acta neurochirurgica

    2023  Volume 165, Issue 11, Page(s) 3297–3298

    MeSH term(s) Humans ; Biomedical Research ; Ethics, Research
    Language English
    Publishing date 2023-09-14
    Publishing country Austria
    Document type Editorial
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-023-05802-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Response to the Letter to the Editor regarding "Promotion of a neurosurgical academic journal on social media: a 1-year experience".

    Staartjes, Victor E / Mathiesen, Tiit

    Acta neurochirurgica

    2024  Volume 166, Issue 1, Page(s) 41

    Language English
    Publishing date 2024-01-27
    Publishing country Austria
    Document type Letter
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-024-05954-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Flemming Gjerris 1936-1924.

    Juhler, Marianne / Waldemar, Gunhild / Meling, Torstein / Mathiesen, Tiit

    Acta neurochirurgica

    2024  Volume 166, Issue 1, Page(s) 183

    Language English
    Publishing date 2024-04-18
    Publishing country Austria
    Document type Editorial
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-024-06082-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Acta Neurochirugica 2019.

    Mathiesen, Tiit

    Acta neurochirurgica

    2019  Volume 161, Issue 1, Page(s) 1

    Language English
    Publishing date 2019-01-11
    Publishing country Austria
    Document type Editorial
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-018-03777-1
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  5. Article: Parasagittal meningiomas.

    Mathiesen, Tiit

    Handbook of clinical neurology

    2020  Volume 170, Page(s) 93–100

    Abstract: Parasagittal meningiomas are defined as meningiomas that grow into at least one wall of the superior sagittal sinus. Long- and short-term morbidity is, in addition to cortical function, related to management of venous structures and flow. Clinical ... ...

    Abstract Parasagittal meningiomas are defined as meningiomas that grow into at least one wall of the superior sagittal sinus. Long- and short-term morbidity is, in addition to cortical function, related to management of venous structures and flow. Clinical management needs to address the extent of removal in the sinus wall and to address relations to the adjacent cortex, which is highly eloquent in the Rolandic and calcarine areas.
    MeSH term(s) Humans ; Meningeal Neoplasms/pathology ; Meningeal Neoplasms/surgery ; Meningioma/pathology ; Meningioma/surgery ; Neurosurgical Procedures/methods ; Superior Sagittal Sinus/pathology ; Superior Sagittal Sinus/surgery
    Language English
    Publishing date 2020-07-13
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-12-822198-3.00031-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Neurosurgery and pregnancy.

    Mathiesen, Tiit

    Acta neurochirurgica

    2018  Volume 160, Issue 7, Page(s) 1359

    Language English
    Publishing date 2018-06-05
    Publishing country Austria
    Document type Editorial
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-018-3581-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The clinical and ethical challenges of treating comatose patients following severe brain injury.

    Rosenfeld, Jeffrey V / Mathiesen, Tiit I

    Acta neurochirurgica

    2022  Volume 165, Issue 4, Page(s) 829–831

    MeSH term(s) Humans ; Coma/etiology ; Coma/therapy ; Brain Injuries
    Language English
    Publishing date 2022-10-04
    Publishing country Austria
    Document type Editorial ; Comment
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-022-05376-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The quality of articles and challenges ahead.

    Mathiesen, Tiit

    Acta neurochirurgica

    2016  Volume 159, Issue 1, Page(s) 1–2

    Language English
    Publishing date 2016-11-21
    Publishing country Austria
    Document type Editorial
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-016-3023-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Machine Learning and Ethics.

    Mathiesen, Tiit / Broekman, Marike

    Acta neurochirurgica. Supplement

    2021  Volume 134, Page(s) 251–256

    Abstract: When new technology is introduced into healthcare, novel ethical dilemmas arise in the human-machine interface. As artificial intelligence (AI), machine learning (ML) and big data can exhaust human oversight and memory capacity, this will give rise to ... ...

    Abstract When new technology is introduced into healthcare, novel ethical dilemmas arise in the human-machine interface. As artificial intelligence (AI), machine learning (ML) and big data can exhaust human oversight and memory capacity, this will give rise to many of these new dilemmas.Technology has little if any ethical status but is inevitably interwoven with human activity and thus may serve to allow qualitative and quantitative disruption of human performance and interaction. We argue that personal integrity, justice of resource allocation and accountability of moral agency comprise three themes that characterize ethical dilemmas that arise with development and application of AI. These themes are important to address in parallel to further evolution of AI in health care for ethical practice of healthcare.
    MeSH term(s) Artificial Intelligence ; Delivery of Health Care ; Humans ; Machine Learning ; Morals ; Technology
    Language English
    Publishing date 2021-12-03
    Publishing country Austria
    Document type Journal Article
    ISSN 0065-1419
    ISSN 0065-1419
    DOI 10.1007/978-3-030-85292-4_28
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Critical ICP thresholds in relation to outcome: Is 22 mmHg really the answer?

    Riparbelli, Agnes C / Capion, Tenna / Møller, Kirsten / Mathiesen, Tiit I / Olsen, Markus H / Forsse, Axel

    Acta neurochirurgica

    2024  Volume 166, Issue 1, Page(s) 63

    Abstract: Purpose: Intensive care for patients with traumatic brain injury (TBI) aims, among other tasks, at avoiding high intracranial pressure (ICP), which is perceived to worsen motor and cognitive deficits and increase mortality. International recommendations ...

    Abstract Purpose: Intensive care for patients with traumatic brain injury (TBI) aims, among other tasks, at avoiding high intracranial pressure (ICP), which is perceived to worsen motor and cognitive deficits and increase mortality. International recommendations for threshold values for ICP were increased from 20 to 22 mmHg in 2016 following the findings in a study by Sorrentino et al., which were based on an observational study of patients with TBI of averaged ICP values. We aimed to reproduce their approach and validate the findings in a separate cohort.
    Methods: Three hundred thirty-one patients with TBI were included and categorised according to survival/death and favourable/unfavourable outcome at 6 months (based on Glasgow Outcome Score-Extended of 6-8 and 1-5, respectively). Repeated chi-square tests of survival and death (or favourable and unfavourable outcome) vs. high and low ICP were conducted with discrimination between high and low ICP sets at increasing values (integers) between 10 and 35 mmHg, using the average ICP for the entire monitoring period. The ICP limit returning the highest chi-square score was assumed to be the threshold with best discriminative ability. This approach was repeated after stratification by sex, age, and initial Glasgow Coma Score (GCS).
    Results: An ICP limit of 18 mmHg was found for both mortality and unfavourable outcome for the entire cohort. The female and the low GCS subgroups both had threshold values of 18 mmHg; for all other subgroups, the threshold varied between 16 and 30 mmHg. According to a multiple logistic regression analysis, age, initial GCS, and average ICP are independently associated with mortality and outcome.
    Conclusions: Using identical methods and closely comparable cohorts, the critical thresholds for ICP found in the study by Sorrentino et al. could not be reproduced.
    MeSH term(s) Humans ; Female ; Intracranial Pressure ; Brain Injuries, Traumatic/diagnosis ; Brain Injuries, Traumatic/therapy ; Critical Care ; Monitoring, Physiologic/methods
    Language English
    Publishing date 2024-02-05
    Publishing country Austria
    Document type Observational Study ; Journal Article
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-024-05929-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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