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  1. Article ; Online: Radiographic signs of gastrointestinal perforation in children: A pictorial review.

    Awolaran, Olugbenga T

    African journal of paediatric surgery : AJPS

    2015  Volume 12, Issue 3, Page(s) 161–166

    Abstract: Plain abdominal radiographs remain an important aid for clinicians in the diagnosis of gastrointestinal perforation, especially in neonates and very sick children where clinical features of peritonitis may not be as prominent. Suggestive radiographic ... ...

    Abstract Plain abdominal radiographs remain an important aid for clinicians in the diagnosis of gastrointestinal perforation, especially in neonates and very sick children where clinical features of peritonitis may not be as prominent. Suggestive radiographic features are not always very obvious, especially when taken in the supine position and may lead to delayed or missed diagnosis. Through a pictorial review of plain radiographs, this article highlights a number of documented features of gastrointestinal perforation on X-ray in the paediatric setting, which increases the accuracy of diagnosis.
    MeSH term(s) Abdominal Injuries/complications ; Abdominal Injuries/diagnosis ; Child ; Humans ; Intestinal Perforation/diagnosis ; Intestinal Perforation/etiology ; Radiography, Abdominal/methods ; Trauma Severity Indices
    Language English
    Publishing date 2015-11-26
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2392865-7
    ISSN 0974-5998 ; 0974-5998
    ISSN (online) 0974-5998
    ISSN 0974-5998
    DOI 10.4103/0189-6725.170177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cellular Mechanisms of Oestrogen in Breast Cancer Development

    Olugbenga T. Awolaran

    Open Access Journal of Science and Technology, Vol 3, Pp 1-

    2015  Volume 7

    Abstract: The association between oestrogen and breast cancer has been demonstrated for over a century however the exact cellular mechanisms by which oestrogen play a role in breast cancer development has not been fully established. Recent investigations have ... ...

    Abstract The association between oestrogen and breast cancer has been demonstrated for over a century however the exact cellular mechanisms by which oestrogen play a role in breast cancer development has not been fully established. Recent investigations have shown that oestrogen is involved in many aspects of cancer progression. This review evaluates how oestrogen at the cellular level induces or promotes the process of breast carcinogenesis through its action at multiple levels of cancer pathogenesis like cellular proliferation, inhibition apoptosis, angiogenesis and invasion-metastasis. Therapeutic approaches against these mechanisms by the use of anti-oestrogens and their effectiveness are also reviewed and areas requiring further investigation are highlighted.
    Keywords Oestrogen ; breast cancer ; mechanism ; carcinogenesis ; Technology ; T ; Science ; Q
    Language English
    Publishing date 2015-06-01T00:00:00Z
    Publisher AgiAl Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Radiographic signs of gastrointestinal perforation in children

    Olugbenga T Awolaran

    African Journal of Paediatric Surgery, Vol 12, Iss 3, Pp 161-

    A pictorial review

    2015  Volume 166

    Abstract: Plain abdominal radiographs remain an important aid for clinicians in the diagnosis of gastrointestinal perforation, especially in neonates and very sick children where clinical features of peritonitis may not be as prominent. Suggestive radiographic ... ...

    Abstract Plain abdominal radiographs remain an important aid for clinicians in the diagnosis of gastrointestinal perforation, especially in neonates and very sick children where clinical features of peritonitis may not be as prominent. Suggestive radiographic features are not always very obvious, especially when taken in the supine position and may lead to delayed or missed diagnosis. Through a pictorial review of plain radiographs, this article highlights a number of documented features of gastrointestinal perforation on X-ray in the paediatric setting, which increases the accuracy of diagnosis.
    Keywords Children ; perforation ; pneumoperitoneum ; radiograph ; signs ; Pediatrics ; RJ1-570 ; Medicine ; R ; Surgery ; RD1-811
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article ; Online: Readmissions after laparoscopic cholecystectomy in a UK District General Hospital.

    Awolaran, Olugbenga / Gana, Tabitha / Samuel, Nehemiah / Oaikhinan, Kenneth

    Surgical endoscopy

    2016  Volume 31, Issue 9, Page(s) 3534–3538

    Abstract: Introduction: Laparoscopic cholecystectomy is the gold standard for the treatment of symptomatic gallstones and its practice as day case where possible is considered the standard over the last decade. However, readmission after surgery is recognised as ... ...

    Abstract Introduction: Laparoscopic cholecystectomy is the gold standard for the treatment of symptomatic gallstones and its practice as day case where possible is considered the standard over the last decade. However, readmission after surgery is recognised as a new problem.
    Aim: The aim of this cohort observational study was to investigate the readmission rate in a district general hospital and identify the causes of readmission in order to explore ways by which this can be reduced or managed more cost effectively.
    Method: Records of patients who had laparoscopic cholecystectomy over 6 months were retrospectively searched. Patients returning to hospital due to symptoms within 30 days of elective and emergency laparoscopic cholecystectomy were included.
    Results: Three hundred and twenty-eight laparoscopic cholecystectomies were performed within the 6-month period. Twenty-two patients returned within 30 days of surgery making a readmission rate of 6.7%. Reasons for inpatient admission were abdominal pain without any underlying cause 10 (45.5%), wound infection 5 (22.7%), leg swelling 2 (9%), retained stone 1 (4.5%), bile leak 1 (4.5%), pneumonia 1 (4.5%), iatrogenic bowel injury 1 (4.5%) and back pain 1 (4.5%). Readmission rate decreased with longer duration of stay in hospital during primary admission, and 64% of patients returned to the hospital within 7 days of procedure. 50% of patients who returned with abdominal pain without any identifiable cause had a longstanding history of conditions involving chronic pain.
    Conclusion: While the feared intra-abdominal complications of cholecystectomy often come to mind when assessing patients presenting with abdominal pain after surgery, non-specific abdominal pain is consistently shown to be several times more likely. A combination of patient factors and pain control techniques account for this pain. Effective multimodal pain management approach and community primary health care support in the early post-operative period could reduce readmission, save cost and improve patient experience.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Cholecystectomy, Laparoscopic ; Female ; Follow-Up Studies ; Hospitals, District ; Hospitals, General ; Humans ; Male ; Middle Aged ; Patient Readmission/statistics & numerical data ; Postoperative Complications/epidemiology ; Retrospective Studies ; United Kingdom
    Language English
    Publishing date 2016-12-23
    Publishing country Germany
    Document type Journal Article ; Observational Study
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-016-5380-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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