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  1. Article: Radiological manifestations of COVID-19: key points for the physician.

    Gravell, Rachel J / Theodoreson, Mark D / Buonsenso, Danilo / Curtis, John

    British journal of hospital medicine (London, England : 2005)

    2020  Volume 81, Issue 6, Page(s) 1–11

    Abstract: The emergence of the SARS-CoV-2 virus at the end of 2019 has led to unprecedented demand on healthcare systems around the world. Healthcare workers, including doctors, have found themselves having to work in unfamiliar environments in the effort to ... ...

    Abstract The emergence of the SARS-CoV-2 virus at the end of 2019 has led to unprecedented demand on healthcare systems around the world. Healthcare workers, including doctors, have found themselves having to work in unfamiliar environments in the effort to control this pandemic. This article gives the hospital physician an overview of the radiological manifestations of COVID-19 disease, to improve knowledge and increase familiarity when reviewing radiographic images.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnostic imaging ; Humans ; Lung/diagnostic imaging ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Radiography, Thoracic ; SARS-CoV-2 ; Tomography, X-Ray Computed ; Ultrasonography
    Keywords covid19
    Language English
    Publishing date 2020-06-12
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1750-8460
    ISSN 1750-8460
    DOI 10.12968/hmed.2020.0231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Radiological manifestations of COVID-19: key points for the physician

    Gravell, Rachel J / Theodoreson, Mark D / Buonsenso, Danilo / Curtis, John

    Br J Hosp Med (Lond)

    Abstract: The emergence of the SARS-CoV-2 virus at the end of 2019 has led to unprecedented demand on healthcare systems around the world. Healthcare workers, including doctors, have found themselves having to work in unfamiliar environments in the effort to ... ...

    Abstract The emergence of the SARS-CoV-2 virus at the end of 2019 has led to unprecedented demand on healthcare systems around the world. Healthcare workers, including doctors, have found themselves having to work in unfamiliar environments in the effort to control this pandemic. This article gives the hospital physician an overview of the radiological manifestations of COVID-19 disease, to improve knowledge and increase familiarity when reviewing radiographic images.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32589534
    Database COVID19

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  3. Article ; Online: Use of QuEChERS as a manual and automated high-throughput protocol for investigating environmental matrices.

    Godfrey, A Ruth / Dunscombe, Jonathan / Gravell, Anthony / Hunter, Ann / Barrow, Mark P / van Keulen, Geertje / Desbrow, Claire / Townsend, Rachel

    Chemosphere

    2022  Volume 308, Issue Pt 2, Page(s) 136313

    Abstract: Environmental pollution has strong links to adverse human health outcomes with risks of pollution through production, use, ineffective wastewater (WW) remediation, and/or leachate from landfill. 'Fit-for-purpose' monitoring approaches are critical for ... ...

    Abstract Environmental pollution has strong links to adverse human health outcomes with risks of pollution through production, use, ineffective wastewater (WW) remediation, and/or leachate from landfill. 'Fit-for-purpose' monitoring approaches are critical for better pollution control and mitigation of harm, with current sample preparation methods for complex environmental matrices typically time-consuming and labour intensive, unsuitable for high-throughput screening. This study has shown that a modified 'Quick Easy Cheap Effective Rugged and Safe' (QuEChERS) sample preparation is a viable alternative for selected environmental matrices required for pollution monitoring (e.g. WW effluent, treated sludge cake and homogenised biota tissue). As a manual approach, reduced extraction times (hours to ∼20 min/sample) with largely reproducible (albeit lower) recoveries of a range of pharmaceuticals and biocidal surfactants have been reported. Its application has shown clear differentiation of matrices via chemometrics, and the measurement of pollutants of interest to the UK WW industry at concentrations significantly above suggested instrument detection limits (IDL) for sludge, indicating insufficient removal and/or bioaccumulation during WW treatment. Furthermore, new pollutant candidates of emerging concern were identified - these included detergents, polymers and pharmaceuticals, with quaternary ammonium compound (QAC) biocides observed at 2.3-70.4 mg/kg, and above levels associated with priority substances for environmental quality regulation (EQSD). Finally, the QuEChERS protocol was adapted to function as a fully automated workflow, further reducing the resource to complete both the preparation and analysis to <40 min. This operated with improved recovery for soil and biota (>62%), and when applied to a largely un-investigated clay matrix, acceptable recovery (88.0-131.1%) and precision (≤10.3% RSD) for the tested pharmaceuticals and biocides was maintained. Therefore, this preliminary study has shown the successful application of a high-throughput QuEChERS protocol across a range of environmental solids for potential deployment in a regulated laboratory.
    MeSH term(s) Clay ; Detergents ; Disinfectants/analysis ; Environmental Pollutants/analysis ; Humans ; Pharmaceutical Preparations ; Polymers/analysis ; Quaternary Ammonium Compounds/analysis ; Sewage ; Solid Phase Extraction/methods ; Tandem Mass Spectrometry/methods ; Waste Water/analysis
    Chemical Substances Detergents ; Disinfectants ; Environmental Pollutants ; Pharmaceutical Preparations ; Polymers ; Quaternary Ammonium Compounds ; Sewage ; Waste Water ; Clay (T1FAD4SS2M)
    Language English
    Publishing date 2022-09-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2022.136313
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: ENCODE whole-genome data in the UCSC Genome Browser: update 2012.

    Rosenbloom, Kate R / Dreszer, Timothy R / Long, Jeffrey C / Malladi, Venkat S / Sloan, Cricket A / Raney, Brian J / Cline, Melissa S / Karolchik, Donna / Barber, Galt P / Clawson, Hiram / Diekhans, Mark / Fujita, Pauline A / Goldman, Mary / Gravell, Robert C / Harte, Rachel A / Hinrichs, Angie S / Kirkup, Vanessa M / Kuhn, Robert M / Learned, Katrina /
    Maddren, Morgan / Meyer, Laurence R / Pohl, Andy / Rhead, Brooke / Wong, Matthew C / Zweig, Ann S / Haussler, David / Kent, W James

    Nucleic acids research

    2011  Volume 40, Issue Database issue, Page(s) D912–7

    Abstract: The Encyclopedia of DNA Elements (ENCODE) Consortium is entering its 5th year of production-level effort generating high-quality whole-genome functional annotations of the human genome. The past year has brought the ENCODE compendium of functional ... ...

    Abstract The Encyclopedia of DNA Elements (ENCODE) Consortium is entering its 5th year of production-level effort generating high-quality whole-genome functional annotations of the human genome. The past year has brought the ENCODE compendium of functional elements to critical mass, with a diverse set of 27 biochemical assays now covering 200 distinct human cell types. Within the mouse genome, which has been under study by ENCODE groups for the past 2 years, 37 cell types have been assayed. Over 2000 individual experiments have been completed and submitted to the Data Coordination Center for public use. UCSC makes this data available on the quality-reviewed public Genome Browser (http://genome.ucsc.edu) and on an early-access Preview Browser (http://genome-preview.ucsc.edu). Visual browsing, data mining and download of raw and processed data files are all supported. An ENCODE portal (http://encodeproject.org) provides specialized tools and information about the ENCODE data sets.
    MeSH term(s) Animals ; Databases, Nucleic Acid ; Genome ; Genome, Human ; Humans ; Internet ; Mice/genetics ; Molecular Sequence Annotation ; Software
    Language English
    Publishing date 2011-11-09
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 186809-3
    ISSN 1362-4962 ; 1362-4954 ; 0301-5610 ; 0305-1048
    ISSN (online) 1362-4962 ; 1362-4954
    ISSN 0301-5610 ; 0305-1048
    DOI 10.1093/nar/gkr1012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1067: Show issues Location:
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