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Book ; Online: Manual Skills, Handedness, and the Organization of Language in the Brain

Króliczak, Gregory / Gonzalez, Claudia L. R. / Carey, David P.

2019

Keywords	Science: general issues ; Psychology ; hand preference ; cerebral dominance ; brain functioning ; sensorimotor control ; higher-order processing ; skilled actions ; praxis ; laterality ; spatial discrimination ; tool affordances
Size	1 electronic resource (163 pages)
Publisher	Frontiers Media SA
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021230721
ISBN	9782889459681 ; 2889459683
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: A Diagnostic Conundrum of Bilateral Optic Disc Edema.

Jeyaseelan, Praveen / Carey, Andrew R

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

2023 Volume 43, Issue 1, Page(s) e40

MeSH term(s)	Humans ; Papilledema/diagnosis ; Papilledema/etiology ; Optic Disk/diagnostic imaging
Language	English
Publishing date	2023-01-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	1189901-3
ISSN	1536-5166 ; 1070-8022
ISSN (online)	1536-5166
ISSN	1070-8022
DOI	10.1097/WNO.0000000000001773
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Expansive Central Ossifying Fibroma of the Right Mandible.

Carey, Kelsey / Koenigsberg, Robert / Kuklani, Riya / Deitrick, Paul

Cureus

2024 Volume 16, Issue 1, Page(s) e52863

Abstract: This case report discusses a 28-year-old patient who presented with a large expansile lesion of the right mandible. A maxillofacial CT showed a 6.7 x 9.1 x 7.6 cm right mandibular cystic mass containing an internal matrix of ground glass bone, ... ...

Abstract	This case report discusses a 28-year-old patient who presented with a large expansile lesion of the right mandible. A maxillofacial CT showed a 6.7 x 9.1 x 7.6 cm right mandibular cystic mass containing an internal matrix of ground glass bone, representing a huge odontogenic keratocyte. Upon biopsy of the lesion, the specimen consisted of non-decalcified irregular fragments of cemento-osseous material, embedded in a minimally hemorrhagic, cellular fibrous tissue stroma, suggestive of central ossifying fibroma. This case presents an ossifying fibroma that far exceeds the average size of these masses, which typically range from 1.0 to 2.5 cm at its greatest dimension. The immense size of the lesion seen in this case is rarely encountered. This case also helps to emphasize the importance of timely diagnosis and complete resection of the lesion to prevent mass recurrence and possible malignant transformation.
Language	English
Publishing date	2024-01-24
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.52863
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effects of Δ⁹-tetrahydrocannabinol (THC), cannabidiol (CBD), and THC/CBD mixtures on fentanyl versus food choice in rhesus monkeys.

Carey, Lawrence M / Maguire, David R / France, Charles P

Drug and alcohol dependence

2023 Volume 244, Page(s) 109787

Abstract: Introduction: There is considerable interest in utilizing cannabis-based products as adjuvants to opioid agonist therapies as phytocannabinoids like Δ: Methods: This study examined the effects of THC and cannabidiol (CBD), the two most prominent ... ...

Abstract	Introduction: There is considerable interest in utilizing cannabis-based products as adjuvants to opioid agonist therapies as phytocannabinoids like Δ Methods: This study examined the effects of THC and cannabidiol (CBD), the two most prominent compounds in cannabis, on the reinforcing effects of fentanyl in rhesus monkeys in a food versus drug choice procedure. Responding on one lever was reinforced by delivery of a sucrose pellet, and responding on another lever was reinforced by delivery of an i.v. infusion of fentanyl. In each monkey, the largest dose of fentanyl that produced less than 20 % drug choice and the smallest dose of fentanyl that produced more than 80% drug choice was determined. Effects of pretreatment with THC and CBD, alone and in mixtures, were then examined. Results: THC, CBD, and THC:CBD mixtures did not reliably enhance or diminish choice for fentanyl up to doses that suppressed responding in most monkeys, though some individual differences were observed, with THC and THC:CBD mixtures decreasing choice for large doses of fentanyl in one monkey and increasing choice for small doses of fentanyl in another. Conclusions: Phytocannabinoids like THC and CBD, administered alone or in mixtures, do not appear to reliably alter the reinforcing effects of opioids.
MeSH term(s)	Animals ; Cannabidiol/pharmacology ; Dronabinol/pharmacology ; Macaca mulatta ; Fentanyl ; Cannabinoid Receptor Agonists/pharmacology ; Hallucinogens ; Cannabis ; Analgesics, Opioid
Chemical Substances	Cannabidiol (19GBJ60SN5) ; Dronabinol (7J8897W37S) ; Fentanyl (UF599785JZ) ; Cannabinoid Receptor Agonists ; Hallucinogens ; Analgesics, Opioid
Language	English
Publishing date	2023-02-01
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	519918-9
ISSN	1879-0046 ; 0376-8716
ISSN (online)	1879-0046
ISSN	0376-8716
DOI	10.1016/j.drugalcdep.2023.109787
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Article ; Online: Objective Diplopia Outcomes for Patients Treated With Teprotumumab for Thyroid Eye Disease.

Mudalegundi, Shwetha / Huang, Peng / Henderson, Amanda D / Carey, Andrew R

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

2023 Volume 44, Issue 1, Page(s) 80–86

Abstract: ... improved. CAS ( P = 0.02) was significantly different among the groups and was higher in those who worsened ... P = 0.01) and left gaze horizontal prism deviation ( P = 0.03) were significantly different ... group ( P = 0.04).: Conclusions: Our study demonstrated that most patients remained stable after ...

Abstract	Background: Thyroid eye disease (TED) is a condition caused by inflammatory damage to the periocular tissue that often leads to double vision. Teprotumumab is an insulin-like growth factor 1 receptor antibody that was FDA approved for the management of TED in 2020, although much is yet to be elucidated regarding its effects on diplopia outcomes among patients with TED. Diplopia is a significant and life-altering effect of TED. Previous studies have reported the effect of teprotumumab on double vision subjectively using the Gorman diplopia score. However, there is a gap in the literature addressing the effect of teprotumumab treatment on objective ocular alignment measures. The purpose of our study was to address this gap. Methods: We performed a retrospective review of patients who were diagnosed with TED, presented with diplopia, and treated with teprotumumab in a single-center academic ophthalmology practice. The primary outcome was change in ocular alignment in primary gaze position at 6 months (completion of teprotumumab treatment). Secondary outcomes included change in ocular alignment in other gaze positions, proptosis, eyelid position, and clinical activity score (CAS) at 6 months compared with baseline. To determine what factors may predict ocular alignment response to teprotumumab, we analyzed baseline characteristics among 3 groups, divided based on whether ocular alignment was worsened, stable, or improved at 6 months. Results: Seventeen patients met inclusion criteria, 3 (18%) worsened, 10 (59%) were stable, and 4 (24%) improved. CAS ( P = 0.02) was significantly different among the groups and was higher in those who worsened and those who improved compared with those who remained stable. Right gaze horizontal prism deviation ( P = 0.01) and left gaze horizontal prism deviation ( P = 0.03) were significantly different among the groups, with a greater degree of left gaze horizontal prism deviation in the worse group than the stable group ( P = 0.04). Conclusions: Our study demonstrated that most patients remained stable after teprotumumab treatment regarding ocular alignment in primary gaze and the number of patients who improved was slightly higher than the number of patients who worsened after teprotumumab treatment. There are some baseline measures, such as CAS and right and left gaze horizontal prism deviation that can help better predict how a patient will respond to teprotumumab treatment. Our results can better inform physicians of how to counsel patients with TED when considering teprotumumab therapy.
MeSH term(s)	Humans ; Graves Ophthalmopathy/complications ; Graves Ophthalmopathy/drug therapy ; Diplopia/diagnosis ; Diplopia/drug therapy ; Diplopia/etiology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Exophthalmos/complications
Chemical Substances	teprotumumab (Y64GQ0KC0A) ; Antibodies, Monoclonal, Humanized
Language	English
Publishing date	2023-09-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	1189901-3
ISSN	1536-5166 ; 1070-8022
ISSN (online)	1536-5166
ISSN	1070-8022
DOI	10.1097/WNO.0000000000002001
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Impact of the COVID-19 Pandemic on Chemistry Student and Staff Perceptions of their Learning/Teaching Experience.

Broad, Harvey / Carey, Niamh / Williams, Dylan P / Blackburn, Richard A R

Journal of chemical education

2023 Volume 100, Issue 2, Page(s) 664–671

Abstract: In response to the COVID-19 pandemic, the University of Leicester introduced a blended teaching model to continue delivery of their undergraduate Chemistry courses in 2020/21. The transition from in-person to blended provided a good opportunity to ... ...

Abstract	In response to the COVID-19 pandemic, the University of Leicester introduced a blended teaching model to continue delivery of their undergraduate Chemistry courses in 2020/21. The transition from in-person to blended provided a good opportunity to investigate student engagement in the blended environment, along with the attitudes of faculty members adapting to this mode of delivery. Data from 94 undergraduate students and 13 staff members was collected using surveys, focus groups, and interviews and analyzed using the community of inquiry framework. Analysis of the collected data found that, while some students felt unable to always engage and focus with the remote material, they were pleased with the University's response to the pandemic. Staff members commented on the challenges of gauging student engagement and understanding in synchronous contact sessions because students did not make use of cameras or microphones but praised the array of digital tools available that helped to facilitate some degree of student interaction. This study suggests there is scope for continuation and wider implementation of blended learning environments to provide additional contingency for further disruption to on-campus teaching and to provide new teaching opportunities, and it also presents recommendations as to how to reinforce the community of inquiry presences in blended learning.
Language	English
Publishing date	2023-02-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	218164-2
ISSN	1938-1328 ; 0021-9584
ISSN (online)	1938-1328
ISSN	0021-9584
DOI	10.1021/acs.jchemed.2c00856
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Article ; Online: Nurses, Clergy, Chaplains, Parkinson's Disease, Workplace Religiosity, Women's Health and Family Issues.

Carey, Lindsay B / Cohen, Jeffery / Drummond, David / Aiken, Carl / Koenig, Harold G / Hill, Terrence / Gabbay, Ezra / Carey, Jacinda R / Paal, Piret

Journal of religion and health

2024 Volume 63, Issue 3, Page(s) 1705–1709

Abstract: This issue of JORH explores a broad range of topics looking at the professions of nursing, clergy and chaplains. This issue also concludes the series on Parkinson's disease (Part 2), and for the first time, JORH presents a collation of articles relating ... ...

Abstract	This issue of JORH explores a broad range of topics looking at the professions of nursing, clergy and chaplains. This issue also concludes the series on Parkinson's disease (Part 2), and for the first time, JORH presents a collation of articles relating to workplace religiosity. Finally, this issue revisits the topics of women's health and family issues in relation to religiosity and spirituality.
MeSH term(s)	Humans ; Parkinson Disease/psychology ; Clergy/psychology ; Women's Health ; Female ; Workplace/psychology ; Spirituality ; Religion and Medicine
Language	English
Publishing date	2024-04-10
Publishing country	United States
Document type	Editorial ; Introductory Journal Article
ZDB-ID	2017250-3
ISSN	1573-6571 ; 0022-4197
ISSN (online)	1573-6571
ISSN	0022-4197
DOI	10.1007/s10943-024-02047-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Clinical Characteristics of Idiopathic Intracranial Hypertension in Older Adults.

Sabet, Sina J / Gasquet, Nicolas C / Henderson, Amanda D / Carey, Andrew R

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

2024

Abstract: ... group. The younger group had a higher rate of headaches (90% vs 63%, P = 0.0004), higher body mass index ... 38.9 vs 36.1, P = 0.046), higher opening pressure (38 vs 31 cm H2O, P = 0.005), and thicker ... peripapillary retinal nerve fiber layer average thickness (right eye 178 vs 131 μm, P = 0.02; left eye 184 vs ...

Abstract	Background: Idiopathic intracranial hypertension (IIH) is a condition that classically affects obese women of child-bearing age. However, it is sometimes encountered in older patients. The purpose of this study was to help clinicians better understand how this disease can present differently in these age groups. Methods: This is a retrospective chart review from a single academic center of baseline characteristics of adult patients diagnosed with IIH based on the modified Dandy criteria. The patients were divided into 2 groups: (1) those 18-44 years old and (2) those older than 45 years at diagnosis. Results: One hundred sixty-seven patients were identified; 135 in the younger group and 32 in the older group. The younger group had a higher rate of headaches (90% vs 63%, P = 0.0004), higher body mass index (38.9 vs 36.1, P = 0.046), higher opening pressure (38 vs 31 cm H2O, P = 0.005), and thicker peripapillary retinal nerve fiber layer average thickness (right eye 178 vs 131 μm, P = 0.02; left eye 184 vs 136 μm, P = 0.045). The older group had higher rates of empty sella (90% vs 62%, P = 0.0039). In addition in the younger group, there was a trend toward higher rates of pulsatile tinnitus (63% vs 45%, P = 0.08), transient visual obscurations (50% vs 32%, P = 0.07), and lower rates of spontaneous cerebrospinal fluid leak (4% vs 13%, P = 0.08). Sex, rates of obesity, other MRI findings typical of elevated intracranial pressure, frequency and Frisen grading of papilledema, and visual field loss were not statistically different between the groups. Conclusions: The older age group had milder signs and symptoms of IIH and a higher prevalence of empty sella than the younger group, but otherwise had typical characteristics. These findings suggest that IIH in the older age group may represent milder chronic disease that was previously undiagnosed.
Language	English
Publishing date	2024-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	1189901-3
ISSN	1536-5166 ; 1070-8022
ISSN (online)	1536-5166
ISSN	1070-8022
DOI	10.1097/WNO.0000000000002055
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Article ; Online: Selective and differential feeding on marine prokaryotes by mucous mesh feeders.

Thompson, Anne W / Sweeney, Carey P / Sutherland, Kelly R

Environmental microbiology

2023 Volume 25, Issue 4, Page(s) 880–893

Abstract: Microbial mortality impacts the structure of food webs, carbon flow, and the interactions that create dynamic patterns of abundance across gradients in space and time in diverse ecosystems. In the oceans, estimates of microbial mortality by viruses, ... ...

Abstract	Microbial mortality impacts the structure of food webs, carbon flow, and the interactions that create dynamic patterns of abundance across gradients in space and time in diverse ecosystems. In the oceans, estimates of microbial mortality by viruses, protists, and small zooplankton do not account fully for observations of loss, suggesting the existence of underappreciated mortality sources. We examined how ubiquitous mucous mesh feeders (i.e. gelatinous zooplankton) could contribute to microbial mortality in the open ocean. We coupled capture of live animals by blue-water diving to sequence-based approaches to measure the enrichment and selectivity of feeding by two coexisting mucous grazer taxa (pteropods and salps) on numerically dominant marine prokaryotes. We show that mucous mesh grazers consume a variety of marine prokaryotes and select between coexisting lineages and similar cell sizes. We show that Prochlorococcus may evade filtration more than other cells and that planktonic archaea are consumed by macrozooplanktonic grazers. Discovery of these feeding relationships identifies a new source of mortality for Earth's dominant marine microbes and alters our understanding of how top-down processes shape microbial community and function.
MeSH term(s)	Animals ; Ecosystem ; Plankton ; Oceans and Seas ; Zooplankton ; Prokaryotic Cells
Language	English
Publishing date	2023-01-10
Publishing country	England
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2020213-1
ISSN	1462-2920 ; 1462-2912
ISSN (online)	1462-2920
ISSN	1462-2912
DOI	10.1111/1462-2920.16334
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Article ; Online: Deep parasternal intercostal plane nerve block: an anatomical study.

Harbell, Monica W / Langley, Natalie R / Seamans, David P / Kraus, Molly B / Carey, Frederick J / Craner, Ryan C

Regional anesthesia and pain medicine

2024 Volume 49, Issue 3, Page(s) 179–183

Abstract: Introduction: The superficial and deep parasternal intercostal plane (DPIP) blocks are two new blocks for thoracic pain. There are limited cadaveric studies evaluating the dye spread with these blocks. In this study, we examined the dye spread of an ... ...

Abstract	Introduction: The superficial and deep parasternal intercostal plane (DPIP) blocks are two new blocks for thoracic pain. There are limited cadaveric studies evaluating the dye spread with these blocks. In this study, we examined the dye spread of an ultrasound-guided DPIP block in a human cadaveric model. Methods: Five ultrasound-guided DPIP blocks were performed in four unembalmed human cadavers using an in-plane approach with a linear transducer oriented in a transverse plane adjacent to the sternum. Twenty milliliters of 0.1% methylene blue were injected between ribs 3 and 4 into the plane deep to the internal intercostal muscles and superficial to the transversus thoracis muscle layer. The chest muscles were dissected, and the extent of dye spread was documented in both cephalocaudal and mediolateral directions. Results: The transversus thoracis muscle slips were stained in all cadavers from 4 to 6 levels. Intercostal nerves were dyed in all specimens. Four levels of intercostal nerves were dyed in each specimen with variability in number of levels stained above and below the level of the injection. Conclusions: The DPIP block spreads along the tissue plane above the transversus thoracis muscles to multiple levels to dye the intercostal nerves in this cadaver study. This block may be of clinical value for analgesia in anterior thoracic surgical procedures.
MeSH term(s)	Humans ; Nerve Block/methods ; Intercostal Nerves/diagnostic imaging ; Ultrasonography ; Cadaver ; Ultrasonography, Interventional/methods ; Iopanoic Acid/analogs & derivatives
Chemical Substances	1,3-dihydroxypropan-2-one 1,3-diiopanoate ; Iopanoic Acid (FE9794P71J)
Language	English
Publishing date	2024-03-04
Publishing country	England
Document type	Journal Article
ZDB-ID	1425299-5
ISSN	1532-8651 ; 1098-7339 ; 0146-521X
ISSN (online)	1532-8651
ISSN	1098-7339 ; 0146-521X
DOI	10.1136/rapm-2023-104716
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