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Article: Yeungnam University type drive-through (YU-Thru) coronavirus disease 2019 (COVID-19) screening system: a rapid and safe screening system.

Seo, Wan Seok / Kim, Seong Ho / Song, Si Youn / Hur, Jian / Lee, Jun / Choi, Sunho / Lee, Yoojung / Bai, Dai Seg

Yeungnam University journal of medicine

2020 Volume 37, Issue 4, Page(s) 349–355

Abstract: ... we then introduced a novel, independently developed system called the Yeungnam University type drive-through (YU ... by fast food restaurants. YU-Thru system has shortened the time taken to test a single person to 2-4 minutes ... requirement was a major drawback of the CSS. YU-Thru system also reduced the risk of subjects and ...

Abstract	Active and prompt scale-up screening tests are essential to efficiently control the coronavirus disease 2019 (COVID-19) outbreak. The goal of this work was to identify shortcomings in the conventional screening system (CSS) implemented in the beginning of the outbreak. To overcome these shortcomings, we then introduced a novel, independently developed system called the Yeungnam University type drive-through (YU-Thru), and distributed it nationwide in Korea. This system is similar to the drive-throughs utilized by fast food restaurants. YU-Thru system has shortened the time taken to test a single person to 2-4 minutes, by completely eliminating the time required to clean and ventilate the specimen collection room. This time requirement was a major drawback of the CSS. YU-Thru system also reduced the risk of subjects and medical staff infecting one another by using a separate and closed examination system. On average, 50 to 60 tests were conducted per day when using the CSS, while now up to 350 tests per day are conducted with the YU-Thru system. We believe that the YU-Thru system has made an important contribution to the rapid detection of COVID-19 in Daegu, South Korea. Here, we will describe the YU-Thru system in detail so that other countries experiencing COVID-19 outbreaks can take advantage of this system.
Keywords	covid19
Language	English
Publishing date	2020-09-18
Publishing country	Korea (South)
Document type	Journal Article
ISSN	2384-0293
ISSN	2384-0293
DOI	10.12701/yujm.2020.00640
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Yeungnam University type drive-through (YU-Thru) coronavirus disease 2019 (COVID-19) screening system

Wan Seok Seo / Seong Ho Kim / Si Youn Song / Jian Hur / Jun Lee / Sunho Choi / Yoojung Lee / Dai Seg Bai

Yeungnam University Journal of Medicine, Vol 37, Iss 4, Pp 349-

a rapid and safe screening system

2020 Volume 355

Abstract: ... we then introduced a novel, independently developed system called the Yeungnam University type drive-through (YU ... by fast food restaurants. YU-Thru system has shortened the time taken to test a single person to 2–4 minutes ... requirement was a major drawback of the CSS. YU-Thru system also reduced the risk of subjects and ...

Abstract	Active and prompt scale-up screening tests are essential to efficiently control the coronavirus disease 2019 (COVID-19) outbreak. The goal of this work was to identify shortcomings in the conventional screening system (CSS) implemented in the beginning of the outbreak. To overcome these shortcomings, we then introduced a novel, independently developed system called the Yeungnam University type drive-through (YU-Thru), and distributed it nationwide in Korea. This system is similar to the drive-throughs utilized by fast food restaurants. YU-Thru system has shortened the time taken to test a single person to 2–4 minutes, by completely eliminating the time required to clean and ventilate the specimen collection room. This time requirement was a major drawback of the CSS. YU-Thru system also reduced the risk of subjects and medical staff infecting one another by using a separate and closed examination system. On average, 50 to 60 tests were conducted per day when using the CSS, while now up to 350 tests per day are conducted with the YU-Thru system. We believe that the YU-Thru system has made an important contribution to the rapid detection of COVID-19 in Daegu, South Korea. Here, we will describe the YU-Thru system in detail so that other countries experiencing COVID-19 outbreaks can take advantage of this system.
Keywords	conventional screening system ; covid-19 ; rapid screening system ; yu-thru system ; Medicine (General) ; R5-920
Subject code	531
Language	English
Publishing date	2020-10-01T00:00:00Z
Publisher	Yeungnam University College of Medicine
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Yeungnam University type drive-through (YU-Thru) coronavirus disease 2019 (COVID-19) screening system: a rapid and safe screening system

Seo, Wan Seok / Kim, Seong Ho / Song, Si Youn / Hur, Jian / Lee, Jun / Choi, Sunho / Lee, Yoojung / Bai, Dai Seg

Abstract	Active and prompt scale-up screening tests are essential to efficiently control the coronavirus disease 2019 (COVID-19) outbreak. The goal of this work was to identify shortcomings in the conventional screening system (CSS) implemented in the beginning of the outbreak. To overcome these shortcomings, we then introduced a novel, independently developed system called the Yeungnam University type drive-through (YU-Thru), and distributed it nationwide in Korea. This system is similar to the drive-throughs utilized by fast food restaurants. YU-Thru system has shortened the time taken to test a single person to 2-4 minutes, by completely eliminating the time required to clean and ventilate the specimen collection room. This time requirement was a major drawback of the CSS. YU-Thru system also reduced the risk of subjects and medical staff infecting one another by using a separate and closed examination system. On average, 50 to 60 tests were conducted per day when using the CSS, while now up to 350 tests per day are conducted with the YU-Thru system. We believe that the YU-Thru system has made an important contribution to the rapid detection of COVID-19 in Daegu, South Korea. Here, we will describe the YU-Thru system in detail so that other countries experiencing COVID-19 outbreaks can take advantage of this system.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32942349
Database	COVID19

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Article: The Association between Persistent Hypertriglyceridemia and the Risk of Diabetes Development: The Kangbuk Samsung Health Study (Endocrinol Metab 2018;33:55-61, Yu Hyun Kwon et al.).

Seo, Mi Hae

Endocrinology and metabolism (Seoul, Korea)

2018 Volume 33, Issue 2, Page(s) 305–306

Language	English
Publishing date	2018-06-27
Publishing country	Korea (South)
Document type	Letter
ZDB-ID	2802452-7
ISSN	2093-5978 ; 2093-596X
ISSN (online)	2093-5978
ISSN	2093-596X
DOI	10.3803/EnM.2018.33.2.305
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Article ; Online: Trends of antimicrobial susceptibilities and multidrug-resistant colonization rate in patients transferred from long-term care facilities during 2017-2022: a cross-sectional study.

Park, Jin Ju / Park, Hyejin / Na, Sun Hee / Seo, Yu Bin / Lee, Jacob

BMC infectious diseases

2024 Volume 24, Issue 1, Page(s) 235

Abstract: Background: With the global increase in the older population, the proportion of those receiving care in long-term care facilities (LTCFs) has also been increasing. We assessed the epidemiology, antibiotic susceptibility, and colonization status of drug- ... ...

Abstract	Background: With the global increase in the older population, the proportion of those receiving care in long-term care facilities (LTCFs) has also been increasing. We assessed the epidemiology, antibiotic susceptibility, and colonization status of drug-resistant organisms in patients transferred from LTCFs. Methods: We retrospectively reviewed the medical records of patients transferred from LTCFs between 2017 and 2022. The reasons for admission, antimicrobial susceptibility, and colonization rates of carbapenem-resistant Enterobacterales (CRE), methicillin-resistant Staphylococcus aureus (MRSA), and carbapenem-resistant Acinetobacter baumannii (CRAB) were recorded. We analyzed the susceptibility and colonization rates by year to identify trends. Results: Of the 936 patients transferred from LTCFs, 54.3% were admitted to the intensive care unit and 12.5% died. The most common reason for admission was infection (n = 573, 61.2%), followed by gastrointestinal bleeding (n = 67, 7.2%) and cerebrovascular disorder (n = 65, 6.9%). A total of 452 Enterobacterales strains were isolated, and their susceptibility rates to ciprofloxacin and cefotaxime were 33.3% and 35.6%, respectively. A total of 54.9% were extended-spectrum beta-lactamase-producing strains, and 4.9% of them were carbapenem-resistant, both of which showed an increasing trend (P = 0.024 and P < 0.001, respectively). The prevalence rates of CRE, CRAB, and MRSA colonization were 9.2%, 7.1%, and 23.1%, respectively. CRE colonization showed a significant increase (P < 0.001), with carbapenemase-producing Enterobacterales accounting for 75.9% of cases. Conclusions: Patients transferred from LTCFs are primarily affected by infections and exhibit high resistance rates. The increasing trend in CRE colonization rates each year highlights the need for the implementation of rigorous infection control measures for effective management.
MeSH term(s)	Humans ; Methicillin-Resistant Staphylococcus aureus ; Cross-Sectional Studies ; Retrospective Studies ; Long-Term Care ; Drug Resistance, Multiple, Bacterial ; Carbapenems/pharmacology ; Anti-Infective Agents/pharmacology ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use
Chemical Substances	Carbapenems ; Anti-Infective Agents ; Anti-Bacterial Agents
Language	English
Publishing date	2024-02-21
Publishing country	England
Document type	Journal Article
ZDB-ID	2041550-3
ISSN	1471-2334 ; 1471-2334
ISSN (online)	1471-2334
ISSN	1471-2334
DOI	10.1186/s12879-024-09145-y
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Article ; Online: Intense Hydrochromic Photon Upconversion from Lead-Free 0D Metal Halides For Water Detection and Information Encryption.

Han, Joo Hyeong / Samanta, Tuhin / Cho, Han Bin / Jang, Sung Woo / Viswanath, N S M / Kim, Yu Ri / Seo, Jeong Min / Im, Won Bin

Advanced materials (Deerfield Beach, Fla.)

2023 Volume 35, Issue 40, Page(s) e2302442

Abstract: Hydrochromic materials that change their luminescence color upon exposure to moisture have attracted considerable attention owing to their applications in sensing and information encryption. However, the existing materials lack high hydrochromic response ...

Abstract	Hydrochromic materials that change their luminescence color upon exposure to moisture have attracted considerable attention owing to their applications in sensing and information encryption. However, the existing materials lack high hydrochromic response and color tunability. This study reports the development of a new and bright 0D Cs
Language	English
Publishing date	2023-08-15
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1474949-X
ISSN	1521-4095 ; 0935-9648
ISSN (online)	1521-4095
ISSN	0935-9648
DOI	10.1002/adma.202302442
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Article: Nirmatrelvir/Ritonavir Prescription Rate and Outcomes in Coronavirus Disease 2019: A Single Center Study.

Park, Jin Ju / Lee, Jacob / Seo, Yu Bin / Na, Sun Hee

Infection & chemotherapy

2022 Volume 54, Issue 4, Page(s) 757–764

Abstract: Background: Nirmatrelvir/ritonavir was Korea's first oral antiviral agent to treat coronavirus disease 2019 (COVID-19). We analyzed the nirmatrelvir/ritonavir prescription rate and treatment outcomes in treatment-eligible patients with COVID-19 ... ...

Abstract	Background: Nirmatrelvir/ritonavir was Korea's first oral antiviral agent to treat coronavirus disease 2019 (COVID-19). We analyzed the nirmatrelvir/ritonavir prescription rate and treatment outcomes in treatment-eligible patients with COVID-19 receiving home-based care. Materials and methods: We retrospectively collected data of patients with COVID-19-eligible for nirmatrelvir/ritonavir treatment from January 14, 2022, to February 15, 2022. We analyzed the prescription rate of nirmatrelvir/ritonavir, the reasons for non-prescription, and patient outcomes. Results: A total of 414 patients were included, of whom 44.2% were male, and the mean age was 64.6 (standard deviation [SD] = 8.5). Approximately 73.2% (n = 303) of patients were not prescribed nirmatrelvir/ritonavir. More than fourth-fifths of the patients refused nirmatrelvir/ritonavir treatment (n = 262, 86.5%). The mean symptom duration was significantly shorter in the prescription group (5.2 days [SD = 2.3] Conclusion: The nirmatrelvir/ritonavir prescription rate was low, with more than fourth-fifths of non-prescriptions being due to patient refusal. Symptom resolution was faster, and no life-threatening side effects were reported. Accurate information about drug safety must be provided to patients to make informed decisions regarding nirmatrelvir/ritonavir treatment.
Language	English
Publishing date	2022-11-18
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2573798-3
ISSN	2093-2340
ISSN	2093-2340
DOI	10.3947/ic.2022.0123
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Article ; Online: Estimation of optimal antiviral stockpile for a novel influenza pandemic.

Kim, Soyoung / Bin Seo, Yu / Lee, Jacob / Kim, Yang Soo / Jung, Eunok

Journal of infection and public health

2022 Volume 15, Issue 7, Page(s) 720–725

Abstract: Background: A stockpile of antiviral drugs is important for mitigating a novel influenza pandemic. Recently, intervention strategies against such a pandemic have improved significantly, affecting the required size and composition of the stockpile. Our ... ...

Abstract	Background: A stockpile of antiviral drugs is important for mitigating a novel influenza pandemic. Recently, intervention strategies against such a pandemic have improved significantly, affecting the required size and composition of the stockpile. Our goal is to estimate the optimal ratio of conventional to newer antiviral drugs. Method: We estimated epidemic parameters from daily-case data about H1N1pdm09 in the Republic of Korea, and used a deterministic ordinary differential equation model and stochastic simulation to predict the number of patients in a future pandemic. We considered an antiviral stockpile containing neuraminidase inhibitors (NAI) and a new drug, cap-dependent endonuclease inhibitor (CENI), seeking the optimum ratio of the two drugs under different epidemiological and economic assumptions. Results: With an effective reproductive number of 1.36, the expected cumulative cases did not exceed 30 % of the population in all vaccination scenarios. If the non-pharmaceutical intervention strategy is intensified and the effective reproductive number is decreased to 1.29, a 20 % antiviral stockpile of the population is sufficient. Assuming that CENI is prescribed for 10 % of patients, the expected total number of cases is decreased from 30 % to approximately 25 % of the population. If the cost of CENI is triple that of NAI, no expenditures beyond the current budget are necessary; if it is quintuple, expenditures increase by 17 %. Conclusion: Stockpiling CENI reduces the number of patients by reducing the infectious period. However, the government needs to consider the cost-effective stockpile ratio of such new drugs. This will depend not only on the cost of the drugs, but on factors difficult to anticipate, such as the transmissibility of the virus, the time needed for vaccine development, and (especially) the emergence of resistance. If this information can be estimated, our model can be used to obtain the optimum.
MeSH term(s)	Antiviral Agents/therapeutic use ; Computer Simulation ; Disease Outbreaks ; Humans ; Influenza Vaccines/therapeutic use ; Influenza, Human/drug therapy ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; Pandemics/prevention & control
Chemical Substances	Antiviral Agents ; Influenza Vaccines
Language	English
Publishing date	2022-05-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2467587-8
ISSN	1876-035X ; 1876-0341
ISSN (online)	1876-035X
ISSN	1876-0341
DOI	10.1016/j.jiph.2022.05.012
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Article ; Online: Fit Test for N95 Filtering Facepiece Respirators and KF94 Masks for Healthcare Workers: a Prospective Single-center Simulation Study.

Park, Jin Ju / Seo, Yu Bin / Lee, Jacob

Journal of Korean medical science

2021 Volume 36, Issue 21, Page(s) e140

Abstract: Background: For protection against coronavirus disease 2019 (COVID-19), the Korean government recommended the KF94 mask or that a mask at the same level as the KF94 should be worn when contacting a patient with COVID-19. Furthermore, adequately fitted ... ...

Abstract	Background: For protection against coronavirus disease 2019 (COVID-19), the Korean government recommended the KF94 mask or that a mask at the same level as the KF94 should be worn when contacting a patient with COVID-19. Furthermore, adequately fitted N95 respirators and KF94 masks are essential. We investigated the fit tests to determine whether healthcare workers had adequate protection with N95 respirators and KF94 masks. Methods: In this prospective single-center simulation study, five N95 respirators (two made in the USA by 3M and three made in Korea) and six KF94 masks, the Korean standard medical masks, were tested. The fit factor (FF) and leakage rate were evaluated using a two-fit test device. Adequate protection (defined as FF ≥ 100 or leakage rate ≤ 5) rates were compared between N95 respirators and KF94 masks, and between made in Korea and the 3M N95 respirators. For KF94 masks, adequate protection rates were compared before and after ear strap fixation. Results: Overall, 30 participants were enrolled, and 330 fit tests were performed for FF and leakage rate. Adequate protection rates of all tested N95 respirators and KF94 masks were 22.7% (n = 75) by FF and 20.6% (n = 68) by leakage rate. N95 respirators showed a significantly higher adequate protection rate than KF94 masks for FF (48.7% vs. 1.1%, Conclusion: Although adequate protection rate of N95 respirators was higher than that of KF94 masks, N95 respirator protection rate was not optimum. Thus, it is necessary to minimize exposure to risk by selecting an appropriate mask or respirator that adequately fits each person, and by wearing respirators or masks appropriately, before contacting the patients. With their superior protection rate, wearing N95 respirators is recommended instead of KF94 masks, especially when performing aerosol-generating procedures.
MeSH term(s)	Adult ; COVID-19/prevention & control ; Computer Simulation ; Female ; Health Personnel ; Humans ; Male ; Masks ; N95 Respirators ; Prospective Studies ; SARS-CoV-2
Language	English
Publishing date	2021-05-31
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	639262-3
ISSN	1598-6357 ; 1011-8934
ISSN (online)	1598-6357
ISSN	1011-8934
DOI	10.3346/jkms.2021.36.e140
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Article: A Noble Extract of

Jung, Su-Bin / Choi, Grace / Kim, Hyo-Jin / Moon, Kyeong-Seo / Lee, Gun / Na, Kyeong-Hak / Kwon, Yong Min / Moon, Jimin / Shin, Mi Yeong / Yu, Jae-Yeong / Baek, Yeong-Bin / Park, Jun-Gyu / Park, Sang-Ik

Microorganisms

2024 Volume 12, Issue 4

Abstract: Epidemic diseases that arise from infectious RNA viruses, particularly influenza viruses, pose a constant threat to the global economy and public health. Viral evolution has undermined the efficacy of acquired immunity from vaccines and the antiviral ... ...

Abstract	Epidemic diseases that arise from infectious RNA viruses, particularly influenza viruses, pose a constant threat to the global economy and public health. Viral evolution has undermined the efficacy of acquired immunity from vaccines and the antiviral effects of FDA-approved drugs. As such, there is an urgent need to develop new antiviral lead agents. Natural compounds, owing to their historical validation of application and safety, have become a promising solution. In this light, a novel marine bacterium,
Language	English
Publishing date	2024-03-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms12040677
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