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  1. Article ; Online: Highlight of 2023: CAR T cells driving precision therapy for autoimmune disease.

    Lee, Adrian Ys / Reed, Joanne H

    Immunology and cell biology

    2024  

    Abstract: CAR T cell therapy is showing remarkable results in autoimmune disease with treatment-refractory patients showing durable drug-free remission. Here, we highlight five key papers from 2023 that are driving the development of CAR T cells to improve ... ...

    Abstract CAR T cell therapy is showing remarkable results in autoimmune disease with treatment-refractory patients showing durable drug-free remission. Here, we highlight five key papers from 2023 that are driving the development of CAR T cells to improve precision, safety, efficacy and accessibility for the treatment of autoantibody-associated autoimmune diseases.
    Language English
    Publishing date 2024-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 284057-1
    ISSN 1440-1711 ; 0818-9641
    ISSN (online) 1440-1711
    ISSN 0818-9641
    DOI 10.1111/imcb.12766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Fostering pathology as a medical discipline among medical students and graduates.

    Lee, Adrian Ys

    British journal of hospital medicine (London, England : 2005)

    2021  Volume 82, Issue 10, Page(s) 1–3

    Abstract: Dwindling interest in pathology as a career is a notable concern among medical students and graduates. Proposed reasons include the lack of exposure during their medical education and the unfavourable view of the discipline. This article discusses the ... ...

    Abstract Dwindling interest in pathology as a career is a notable concern among medical students and graduates. Proposed reasons include the lack of exposure during their medical education and the unfavourable view of the discipline. This article discusses the barriers for adoption of pathology as a career and strategies to overcome this.
    MeSH term(s) Career Choice ; Education, Medical ; Humans ; Students, Medical
    Language English
    Publishing date 2021-10-14
    Publishing country England
    Document type Editorial
    ISSN 1750-8460
    ISSN 1750-8460
    DOI 10.12968/hmed.2021.0504
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Rapid publishing in the era of coronavirus disease 2019 (COVID-19).

    Lee, Adrian Ys / Lin, Ming-Wei

    The Medical journal of Australia

    2020  Volume 212, Issue 11, Page(s) 535–535.e1

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Publishing/trends ; SARS-CoV-2 ; Time Factors
    Keywords covid19
    Language English
    Publishing date 2020-05-31
    Publishing country Australia
    Document type Letter
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.50617
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Interferon signatures in systemic lupus erythematosus patients across ethnic groups.

    Gazy, Nicholas E / Fewings, Nicole L / Emerson, Jonathan / Swaminathan, Sanjay / Lee, Adrian Ys / Lin, Ming-Wei

    Lupus

    2023  Volume 32, Issue 10, Page(s) 1231–1232

    MeSH term(s) Humans ; Interferons ; Ethnicity ; Lupus Erythematosus, Systemic/drug therapy ; Interferon Type I
    Chemical Substances Interferons (9008-11-1) ; Interferon Type I
    Language English
    Publishing date 2023-08-10
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1154407-7
    ISSN 1477-0962 ; 0961-2033
    ISSN (online) 1477-0962
    ISSN 0961-2033
    DOI 10.1177/09612033231194211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Granulomatous skin lesions of common variable immunodeficiency treated with sirolimus.

    Lee, Adrian Ys / Huynh, Nghi / Lin, Ming-Wei

    The Australasian journal of dermatology

    2021  Volume 62, Issue 3, Page(s) 434–435

    MeSH term(s) Aged ; Common Variable Immunodeficiency/complications ; Common Variable Immunodeficiency/physiopathology ; Exanthema/etiology ; Face/abnormalities ; Face/physiopathology ; Female ; Granuloma/complications ; Granuloma/diagnosis ; Granuloma/pathology ; Humans
    Language English
    Publishing date 2021-03-04
    Publishing country Australia
    Document type Case Reports ; Letter
    ZDB-ID 138052-7
    ISSN 1440-0960 ; 0004-8380
    ISSN (online) 1440-0960
    ISSN 0004-8380
    DOI 10.1111/ajd.13574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A case of rash and arthralgias.

    Lee, Adrian YS / Ang, Eugene BH

    Australian journal of general practice

    2019  Volume 48, Issue 9, Page(s) 609–611

    MeSH term(s) Ankle ; Arthralgia/etiology ; Arthritis, Infectious/diagnosis ; Cellulitis/diagnosis ; Diagnosis, Differential ; Exanthema/etiology ; Female ; Glucocorticoids/therapeutic use ; Humans ; Middle Aged ; Prednisolone/therapeutic use ; Vasculitis, Leukocytoclastic, Cutaneous/complications ; Vasculitis, Leukocytoclastic, Cutaneous/diagnosis ; Vasculitis, Leukocytoclastic, Cutaneous/drug therapy ; Vasculitis, Leukocytoclastic, Cutaneous/pathology
    Chemical Substances Glucocorticoids ; Prednisolone (9PHQ9Y1OLM)
    Language English
    Publishing date 2019-09-02
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 2924889-9
    ISSN 2208-7958 ; 2208-794X
    ISSN (online) 2208-7958
    ISSN 2208-794X
    DOI 10.31128/AJGP-12-18-4792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: CC chemokine receptor 6 (CCR6) in the pathogenesis of systemic lupus erythematosus.

    Lee, Adrian Ys / Körner, Heinrich

    Immunology and cell biology

    2020  Volume 98, Issue 10, Page(s) 845–853

    Abstract: The CC chemokine receptor 6 (CCR6) and its sole chemokine ligand, CCL20, are an intriguing pair that have been implicated in a growing number of inflammatory, autoimmune and malignant disease processes. Recent observations have also highlighted this ... ...

    Abstract The CC chemokine receptor 6 (CCR6) and its sole chemokine ligand, CCL20, are an intriguing pair that have been implicated in a growing number of inflammatory, autoimmune and malignant disease processes. Recent observations have also highlighted this chemokine axis in the regulation of humoral immune responses. Through this review article, we explore the emerging links of CCR6-CCL20 with an archetypal autoimmune disease of humoral dysregulation: systemic lupus erythematosus (SLE). CCR6 is expressed prominently on several immune cells involved in the pathogenesis of SLE, such as dendritic cells and T-helper 17 cells. CCR6's expression is correlated with disease activity and serological markers of disease severity, suggesting a possible role in disease pathogenesis. However, there are numerous holes in our understanding of the functions of CCR6 and CCL20, and future studies are required to determine if there are any diagnostic, prognostic or monitoring roles for these important molecules.
    MeSH term(s) Chemokine CCL20/immunology ; Dendritic Cells ; Humans ; Immunity, Humoral ; Lupus Erythematosus, Systemic/pathology ; Receptors, CCR6/immunology ; Th17 Cells
    Chemical Substances CCL20 protein, human ; CCR6 protein, human ; Chemokine CCL20 ; Receptors, CCR6
    Language English
    Publishing date 2020-08-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 284057-1
    ISSN 1440-1711 ; 0818-9641
    ISSN (online) 1440-1711
    ISSN 0818-9641
    DOI 10.1111/imcb.12375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Rapid publishing in the era of coronavirus disease 2019 ( COVID ‐19)

    Lee, Adrian YS / Lin, Ming‐Wei

    Medical Journal of Australia

    2020  Volume 212, Issue 11, Page(s) 535

    Keywords General Medicine ; covid19
    Language English
    Publisher AMPCo
    Publishing country au
    Document type Article ; Online
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.50617
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Rapid publishing in the era of coronavirus disease 2019 (COVID-19)

    Lee, Adrian YS / Lin, Ming-Wei

    2020  

    Abstract: he advent of coronavirus disease 2019 (COVID‐19) has generated an unparalleled level of interest from the medical and non‐medical community. As clinician‐scientists, we watch in astonishment at the exponential growth of academic publications in journals. ...

    Abstract he advent of coronavirus disease 2019 (COVID‐19) has generated an unparalleled level of interest from the medical and non‐medical community. As clinician‐scientists, we watch in astonishment at the exponential growth of academic publications in journals. In January 2020, PubMed saw a sharp rise in the number of publications related to COVID‐19, which continues to grow.
    Keywords COVID-19 ; Coronavirus ; covid19
    Language English
    Publishing date 2020-01-01
    Publishing country au
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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