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Article ; Online: Mediastinal cysts associated with Paragonimus westermani.

Chae, Kum Ju / Kim, Jong Hun

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2023 Volume 133, Page(s) 82–84

MeSH term(s)	Animals ; Humans ; Paragonimus westermani ; Mediastinal Cyst ; Paragonimiasis/diagnosis ; Paragonimiasis/drug therapy
Language	English
Publishing date	2023-05-06
Publishing country	Canada
Document type	Journal Article
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2023.05.001
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Zs.A 4516: Show issues

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Article ; Online: Structural and functional features of asthma participants with fixed airway obstruction using CT imaging and 1D computational fluid dynamics: A feasibility study.

Nguyen, Quoc Hung / Kim, So Ri / Chae, Kum Ju / Jin, Gong Yong / Choi, Sanghun

Physiological reports

2024 Volume 12, Issue 1, Page(s) e15909

Abstract: Asthma with fixed airway obstruction (FAO) is associated with significant morbidity and rapid decline in lung function, making its treatment challenging. Quantitative computed tomography (QCT) along with data postprocessing is a useful tool to obtain ... ...

Abstract	Asthma with fixed airway obstruction (FAO) is associated with significant morbidity and rapid decline in lung function, making its treatment challenging. Quantitative computed tomography (QCT) along with data postprocessing is a useful tool to obtain detailed information on airway structure, parenchymal function, and computational flow features. In this study, we aim to identify the structural and functional differences between asthma with and without FAO. The FAO group was defined by a ratio of forced expiratory volume in 1 s (FEV
MeSH term(s)	Humans ; Feasibility Studies ; Hydrodynamics ; Asthma/complications ; Asthma/diagnostic imaging ; Airway Obstruction/diagnostic imaging ; Tomography, X-Ray Computed
Language	English
Publishing date	2024-01-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2724325-4
ISSN	2051-817X ; 2051-817X
ISSN (online)	2051-817X
ISSN	2051-817X
DOI	10.14814/phy2.15909
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Article ; Online: Giant Fibrovascular Polyp Mimicking Esophageal Malignancy on 18 F-FDG PET/CT.

Kim, MinJeong / Chae, Kum Ju / Kim, Jong-Hun / Han, Yeon-Hee

Clinical nuclear medicine

2023 Volume 48, Issue 12, Page(s) 1091–1092

Abstract: Abstract: A 52-year-old man presented with continuous dull pain from the throat to the epigastric region with dysphagia. Initial endoscopy misdiagnosed a subepithelial tumor causing external compression of the esophagus. A CT scan visualized a 14.0 × 4 ... ...

Abstract	Abstract: A 52-year-old man presented with continuous dull pain from the throat to the epigastric region with dysphagia. Initial endoscopy misdiagnosed a subepithelial tumor causing external compression of the esophagus. A CT scan visualized a 14.0 × 4.0-cm pedunculated mass inside the esophagus. Subsequent 18 F-FDG PET/CT identified an intense FDG-avid area in the mass, which strongly suggested esophageal cancer. Total mass excision was performed, and fibrovascular polyp with chronic ulcerative inflammation was finally confirmed on histologic examination.
MeSH term(s)	Male ; Humans ; Middle Aged ; Positron Emission Tomography Computed Tomography ; Fluorodeoxyglucose F18 ; Esophageal Neoplasms/pathology ; Endoscopy ; Polyps/pathology
Chemical Substances	Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2023-10-25
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	197628-x
ISSN	1536-0229 ; 0363-9762
ISSN (online)	1536-0229
ISSN	0363-9762
DOI	10.1097/RLU.0000000000004907
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Zs.A 1276: Show issues

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Article ; Online: Rapidly Progressive COVID-19 Pneumonia: What Radiologists Should Do.

Chae, Kum Ju / Jin, Gong Yong

Korean journal of radiology

2020 Volume 21, Issue 6, Page(s) 773–776

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Negative Results ; Pandemics ; Pneumonia, Viral ; RNA-Directed DNA Polymerase ; Radiologists ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Tomography, X-Ray Computed
Chemical Substances	RNA-Directed DNA Polymerase (EC 2.7.7.49)
Keywords	covid19
Language	English
Publishing date	2020-06-26
Publishing country	Korea (South)
Document type	Letter ; Comment
ZDB-ID	2046981-0
ISSN	2005-8330 ; 1229-6929
ISSN (online)	2005-8330
ISSN	1229-6929
DOI	10.3348/kjr.2020.0364
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Zs.A 5591: Show issues

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Article ; Online: Invasive Hypervirulent

Chae, Kum Ju / Lee, Jaehyeon / Hwang, Joo-Hee / Hwang, Jeong-Hwan

Medicina (Kaunas, Lithuania)

2022 Volume 58, Issue 10

Abstract: An immunocompetent 49-year-old man presented with swelling and pain in the lower region of his left leg that had lasted for 4 weeks. The diagnosis was severe pyomyositis and osteomyelitis in the lower left leg caused by ... ...

Abstract	An immunocompetent 49-year-old man presented with swelling and pain in the lower region of his left leg that had lasted for 4 weeks. The diagnosis was severe pyomyositis and osteomyelitis in the lower left leg caused by hypervirulent
MeSH term(s)	Male ; Humans ; Middle Aged ; Klebsiella pneumoniae/genetics ; Liver Abscess, Pyogenic/complications ; Liver Abscess, Pyogenic/diagnosis ; Klebsiella Infections/complications ; Klebsiella Infections/diagnosis ; Klebsiella Infections/drug therapy ; Ceftriaxone/therapeutic use ; Pyomyositis ; Osteomyelitis
Chemical Substances	Ceftriaxone (75J73V1629)
Language	English
Publishing date	2022-10-14
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina58101450
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Zs.A 6270: Show issues

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Article ; Online: Chronic Lung Injury after COVID-19 Pneumonia: Clinical, Radiologic, and Histopathologic Perspectives.

Cha, Min Jae / Solomon, Joshua J / Lee, Jong Eun / Choi, Hyewon / Chae, Kum Ju / Lee, Kyung Soo / Lynch, David A

Radiology

2024 Volume 310, Issue 1, Page(s) e231643

Abstract: With the COVID-19 pandemic having lasted more than 3 years, concerns are growing about prolonged symptoms and respiratory complications in COVID-19 survivors, collectively termed post-COVID-19 condition (PCC). Up to 50% of patients have residual symptoms ...

Abstract	With the COVID-19 pandemic having lasted more than 3 years, concerns are growing about prolonged symptoms and respiratory complications in COVID-19 survivors, collectively termed post-COVID-19 condition (PCC). Up to 50% of patients have residual symptoms and physiologic impairment, particularly dyspnea and reduced diffusion capacity. Studies have also shown that 24%-54% of patients hospitalized during the 1st year of the pandemic exhibit radiologic abnormalities, such as ground-glass opacity, reticular opacity, bronchial dilatation, and air trapping, when imaged more than 1 year after infection. In patients with persistent respiratory symptoms but normal results at chest CT, dual-energy contrast-enhanced CT, xenon 129 MRI, and low-field-strength MRI were reported to show abnormal ventilation and/or perfusion, suggesting that some lung injury may not be detectable with standard CT. Histologic patterns in post-COVID-19 lung disease include fibrosis, organizing pneumonia, and vascular abnormality, indicating that different pathologic mechanisms may contribute to PCC. Therefore, a comprehensive imaging approach is necessary to evaluate and diagnose patients with persistent post-COVID-19 symptoms. This review will focus on the long-term findings of clinical and radiologic abnormalities and describe histopathologic perspectives. It also addresses advanced imaging techniques and deep learning approaches that can be applied to COVID-19 survivors. This field remains an active area of research, and further follow-up studies are warranted for a better understanding of the chronic stage of the disease and developing a multidisciplinary approach for patient management.
MeSH term(s)	Humans ; Lung Injury/diagnostic imaging ; Lung Injury/etiology ; COVID-19/complications ; COVID-19/diagnostic imaging ; Pandemics ; Post-Acute COVID-19 Syndrome ; Bronchi
Language	English
Publishing date	2024-01-09
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.231643
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Ue I Zs.106: Show issues

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Article ; Online: Measurement Variability of Same-Day CT Quantification of Interstitial Lung Disease: A Multicenter Prospective Study.

Lee, Jong Hyuk / Chae, Kum Ju / Park, Jimyung / Choi, Sun Mi / Jang, Myoung-Jin / Hwang, Eui Jin / Jin, Gong Yong / Goo, Jin Mo

Radiology. Cardiothoracic imaging

2024 Volume 6, Issue 2, Page(s) e230287

Abstract: Purpose To investigate quantitative CT (QCT) measurement variability in interstitial lung disease (ILD) on the basis of two same-day CT scans. Materials and Methods Participants with ILD were enrolled in this multicenter prospective study between March ... ...

Abstract	Purpose To investigate quantitative CT (QCT) measurement variability in interstitial lung disease (ILD) on the basis of two same-day CT scans. Materials and Methods Participants with ILD were enrolled in this multicenter prospective study between March and October 2022. Participants underwent two same-day CT scans at an interval of a few minutes. Deep learning-based texture analysis software was used to segment ILD features. Fibrosis extent was defined as the sum of reticular opacity and honeycombing cysts. Measurement variability between scans was assessed with Bland-Altman analyses for absolute and relative differences with 95% limits of agreement (LOA). The contribution of fibrosis extent to variability was analyzed using a multivariable linear mixed-effects model while adjusting for lung volume. Eight readers assessed ILD fibrosis stability with and without QCT information for 30 randomly selected samples. Results Sixty-five participants were enrolled in this study (mean age, 68.7 years ± 10 [SD]; 47 [72%] men, 18 [28%] women). Between two same-day CT scans, the 95% LOA for the mean absolute and relative differences of quantitative fibrosis extent were -0.9% to 1.0% and -14.8% to 16.1%, respectively. However, these variabilities increased to 95% LOA of -11.3% to 3.9% and -123.1% to 18.4% between CT scans with different reconstruction parameters. Multivariable analysis showed that absolute differences were not associated with the baseline extent of fibrosis (
MeSH term(s)	Aged ; Female ; Humans ; Male ; Linear Models ; Lung Diseases, Interstitial/diagnosis ; Prospective Studies ; Pulmonary Fibrosis ; Tomography, X-Ray Computed ; Middle Aged
Language	English
Publishing date	2024-04-30
Publishing country	United States
Document type	Multicenter Study ; Journal Article
ISSN	2638-6135
ISSN (online)	2638-6135
DOI	10.1148/ryct.230287
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Article: Rapidly Progressive COVID-19 Pneumonia: What Radiologists Should Do

Chae, Kum Ju / Jin, Gong Yong

Korean J Radiol

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32410416
Database	COVID19

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Article ; Online: Quantitative Assessment of Airway Changes in Fibrotic Interstitial Lung Abnormality Patients by Chest CT According to Cumulative Cigarette Smoking.

Li, Yuan Zhe / Jin, Gong Yong / Chae, Kum Ju / Han, Young Min

Tomography (Ann Arbor, Mich.)

2022 Volume 8, Issue 2, Page(s) 1024–1032

Abstract: Purpose: The aim of this study was to evaluate the role of Pi10 in patients with fibrotic interstitial lung abnormality (fibrotic ILA) in a chest CT, according to cumulative cigarette smoking. Methods: We retrospectively assessed 54 fibrotic ILA patients ...

Abstract	Purpose: The aim of this study was to evaluate the role of Pi10 in patients with fibrotic interstitial lung abnormality (fibrotic ILA) in a chest CT, according to cumulative cigarette smoking. Methods: We retrospectively assessed 54 fibrotic ILA patients and 18 healthy non-smokers (control) who underwent non-enhanced CT and pulmonary function tests. We quantitatively analyzed airway changes (the inner luminal area, airway inner parameter, airway wall thickness, Pi10, skewness, and kurtosis) in the chest CT of fibrotic ILA patients, and the fibrotic ILA patients were categorized into groups based on pack-years: light, moderate, heavy. Airway change data and pulmonary function tests among the three groups of fibrotic ILA patients were compared with those of the control group by one-way ANOVA. Results: Mean skewness (2.58 ± 0.36) and kurtosis (7.64 ± 2.36) in the control group were significantly different from those of the fibrotic ILA patients (1.89 ± 0.37 and 3.62 ± 1.70, respectively, p < 0.001). In fibrotic ILA group, only heavy smokers had significantly increased Pi10 (mean increase 0.04, p = 0.013), increased airway wall thickness of the segmental bronchi (mean increase 0.06 mm, p = 0.005), and decreased lung diffusing capacity for carbon monoxide (p = 0.023). Conclusion: Pi10, as a biomaker of quantitative CT in fibrotic ILA patients, can reveal that smoking affects airway remodeling.
MeSH term(s)	Cigarette Smoking ; Humans ; Lung/diagnostic imaging ; Lung Diseases, Interstitial/diagnostic imaging ; Retrospective Studies ; Tomography, X-Ray Computed
Language	English
Publishing date	2022-04-03
Publishing country	Switzerland
Document type	Journal Article
ISSN	2379-139X
ISSN (online)	2379-139X
DOI	10.3390/tomography8020082
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Article: Prognosis and recurrence patterns in patients with early stage lung cancer: a multi-state model approach.

Jeong, Won Gi / Choi, Hyemi / Chae, Kum Ju / Kim, Jinheum

Translational lung cancer research

2022 Volume 11, Issue 7, Page(s) 1279–1291

Abstract: Background: We aimed to assess whether recurrence patterns affect survival and to use a multi-state model to predict the prognosis of early stage non-small cell lung cancer in patients who underwent surgical resection.: Methods: Patients with early ... ...

Abstract	Background: We aimed to assess whether recurrence patterns affect survival and to use a multi-state model to predict the prognosis of early stage non-small cell lung cancer in patients who underwent surgical resection. Methods: Patients with early stage non-small cell lung cancer who underwent surgical resection at two tertiary medical centers between 2010 and 2015 were retrospectively analyzed. A multi-state model was employed with one initial state (surgery), two intermediate states (locoregional recurrence, distant metastasis), and one absorbing state (death), comprising five transitions: surgery to locoregional recurrence, surgery to distant metastasis, surgery to death without recurrence, locoregional recurrence to death, and distant metastasis to death. Cox proportional hazards models stratified for these transitions were performed with the risk factors; transition probabilities for each patient were predicted. Results: A total of 949 patients were identified [median age: 67 years, male: 614 (64.6%)]. Recurrence occurred in 194 (20.4%) patients (locoregional recurrence: 7.3%, distant metastasis: 13.1%). Hazard ratios for distant metastasis after surgery were higher for older age (hazard ratio: 1.03, 95% confidence interval: 1.01-1.06) and adenocarcinoma (hazard ratio: 1.67, 95% confidence interval: 1.06-2.61). Lower lobe location exhibited a higher hazard ratio for death after surgery without recurrence (hazard ratio: 1.59, 95% confidence interval: 1.00-2.53). Stage IIB lung cancer showed a higher probability of transition to distant metastasis after surgery than other stages. Cumulative transition hazards rapidly increased in both recurrence patterns until approximately two years after surgery (locoregional recurrence: 0.052; distant metastasis: 0.104). Patients with distant metastasis were more likely to die within 5 years of surgery than those with locoregional recurrence (6.8% and 2.6%, respectively). Conclusions: With the multi-state model, risk factors and post-relapse survival probabilities differed between locoregional recurrence and distant metastasis. These findings may enable clinicians to establish personalized follow-up strategies for patients undergoing curative resection for early stage non-small cell lung cancer.
Language	English
Publishing date	2022-07-26
Publishing country	China
Document type	Journal Article
ZDB-ID	2754335-3
ISSN	2226-4477 ; 2218-6751
ISSN (online)	2226-4477
ISSN	2218-6751
DOI	10.21037/tlcr-22-148
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