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  1. Book ; Online: Social Development in the World Bank : Essays in Honor of Michael M. Cernea

    Koch-Weser, Maritta / Guggenheim, Scott

    2021  

    Keywords Society & social sciences ; Development studies ; Central government policies ; Sociology ; Social Sciences, general ; Development Studies ; Environmental Policy ; Sociology, general ; Sociological Methods ; Environmental Social Sciences ; Social Development ; World Bank ; International Development Aid ; Development Anthropology ; Sustainable Development ; Open Access ; Society & Social Sciences ; Central / national / federal government policies
    Size 1 electronic resource (368 pages)
    Publisher Springer Nature
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021047352
    ISBN 9783030574260 ; 3030574261
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Enhancing the Equilibrium of Dynamic Thia-Michael Reactions through Heterocyclic Design.

    Crolais, Alex E / Dolinski, Neil D / Boynton, Nicholas R / Radhakrishnan, Julia M / Snyder, Scott A / Rowan, Stuart J

    Journal of the American Chemical Society

    2023  Volume 145, Issue 26, Page(s) 14427–14434

    Abstract: Although the catalyst-free dynamic thia-Michael (tM) reaction has been leveraged for a range ... of catalyst-free, room-temperature dynamic thia-Michael acceptors bearing an isoxazolone motif were developed ...

    Abstract Although the catalyst-free dynamic thia-Michael (tM) reaction has been leveraged for a range of significant applications in materials science and pharmaceutical development, exploiting its full potential has been limited by relatively low equilibrium constants. To address this shortcoming, a new series of catalyst-free, room-temperature dynamic thia-Michael acceptors bearing an isoxazolone motif were developed and utilized to access both dynamic covalent networks and linear polymers. By leveraging the generation of aromaticity upon thiol addition and tuning the electronic-withdrawing/donating nature of the acceptor at two different sites, a wide range of equilibrium constants (
    Language English
    Publishing date 2023-06-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c03643
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  3. Article ; Online: Thiol-Michael Addition Microparticles: Their Synthesis, Characterization, and Uptake by Macrophages.

    Grey, Emerson L / McClendon, Jazalle / Suresh, Joshita / Alper, Scott / Janssen, William J / Bryant, Stephanie J

    ACS biomaterials science & engineering

    2023  Volume 9, Issue 7, Page(s) 4223–4240

    Abstract: ... in the treatment of disease. This study investigates microparticles formed by a thiol-Michael addition step-growth ...

    Abstract Polymeric microparticles are promising biomaterial platforms for targeting macrophages in the treatment of disease. This study investigates microparticles formed by a thiol-Michael addition step-growth polymerization reaction with tunable physiochemical properties and their uptake by macrophages. The hexafunctional thiol monomer dipentaerythritol hexa-3-mercaptopropionate (DPHMP) and tetrafunctional acrylate monomer di(trimethylolpropane) tetraacrylate (DTPTA) were reacted in a stepwise dispersion polymerization, achieving tunable monodisperse particles over a size range (1-10 μm) relevant for targeting macrophages. An off-stoichiometry thiol-acrylate reaction afforded facile secondary chemical functionalization to create particles with different chemical moieties. Uptake of the microparticles by RAW 264.7 macrophages was highly dependent on treatment time, particle size, and particle chemistry with amide, carboxyl, and thiol terminal chemistries. The amide-terminated particles were non-inflammatory, while the carboxyl- and thiol-terminated particles induced pro-inflammatory cytokine production in conjunction with particle phagocytosis. Finally, a lung-specific application was explored through time-dependent uptake of amide-terminated particles by human alveolar macrophages
    MeSH term(s) Animals ; Mice ; Humans ; Sulfhydryl Compounds/chemistry ; Macrophages ; Acrylates/chemistry ; Amides
    Chemical Substances Sulfhydryl Compounds ; acrylic acid (J94PBK7X8S) ; Acrylates ; Amides
    Language English
    Publishing date 2023-06-28
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
    ISSN 2373-9878
    ISSN (online) 2373-9878
    DOI 10.1021/acsbiomaterials.3c00441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Michael Benjamin Hopkins, MD, FACS, FASCRS.

    Steele, Scott R

    Clinics in colon and rectal surgery

    2021  Volume 34, Issue 4, Page(s) 201–202

    Language English
    Publishing date 2021-04-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2048635-2
    ISSN 1531-0043
    ISSN 1531-0043
    DOI 10.1055/s-0041-1726452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3931: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Michael A. Valente, DO, FACS, FASCRS.

    Steele, Scott R

    Clinics in colon and rectal surgery

    2019  Volume 32, Issue 4, Page(s) 221–222

    Language English
    Publishing date 2019-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2048635-2
    ISSN 1531-0043
    ISSN 1531-0043
    DOI 10.1055/s-0039-1683851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3931: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Michael Benjamin Hopkins, MD, FACS, FASCRS

    Steele, Scott R.

    Clinics in Colon and Rectal Surgery

    (Bowel Obstructions)

    2021  Volume 34, Issue 04, Page(s) 201–202

    Series title Bowel Obstructions
    Language English
    Publishing date 2021-04-19
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2048635-2
    ISSN 1530-9681 ; 1531-0043
    ISSN (online) 1530-9681
    ISSN 1531-0043
    DOI 10.1055/s-0041-1726452
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3931: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Characterization and structure-property relationships of an injectable thiol-Michael addition hydrogel toward compatibility with glioblastoma therapy.

    Khan, Zerin Mahzabin / Wilts, Emily / Vlaisavljevich, Eli / Long, Timothy E / Verbridge, Scott S

    Acta biomaterialia

    2022  Volume 144, Page(s) 266–278

    Abstract: ... crosslinked via a thiol-Michael addition reaction by tuning its hydration level and aqueous NaHCO ...

    Abstract Glioblastoma multiforme (GBM) is an aggressive primary brain cancer and although patients undergo surgery and chemoradiotherapy, residual cancer cells still migrate to healthy brain tissue and lead to tumor relapse after treatment. New therapeutic strategies are therefore urgently needed to better mitigate this tumor recurrence. To address this need, we envision after surgical removal of the tumor, implantable biomaterials in the resection cavity can treat or collect residual GBM cells for their subsequent eradication. To this end, we systematically characterized a poly(ethylene glycol)-based injectable hydrogel crosslinked via a thiol-Michael addition reaction by tuning its hydration level and aqueous NaHCO
    MeSH term(s) Biocompatible Materials/therapeutic use ; Glioblastoma/drug therapy ; Glioblastoma/pathology ; Humans ; Hydrogels/chemistry ; Neoplasm Recurrence, Local ; Polymers/therapeutic use ; Sulfhydryl Compounds/chemistry ; Tumor Microenvironment
    Chemical Substances Biocompatible Materials ; Hydrogels ; Polymers ; Sulfhydryl Compounds
    Language English
    Publishing date 2022-03-14
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 2173841-5
    ISSN 1878-7568 ; 1742-7061
    ISSN (online) 1878-7568
    ISSN 1742-7061
    DOI 10.1016/j.actbio.2022.03.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Michael A. Valente, DO, FACS, FASCRS

    Steele, Scott R.

    Clinics in Colon and Rectal Surgery

    (Complex Crohn's Disease: Primum non nocere)

    2019  Volume 32, Issue 04, Page(s) 221–222

    Series title Complex Crohn's Disease: Primum non nocere
    Language English
    Publishing date 2019-06-17
    Publisher Thieme Medical Publishers
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2048635-2
    ISSN 1530-9681 ; 1531-0043
    ISSN (online) 1530-9681
    ISSN 1531-0043
    DOI 10.1055/s-0039-1683851
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3931: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Michael F. McGee, MD, FACS, FASCRS.

    Steele, Scott R

    Clinics in colon and rectal surgery

    2017  Volume 30, Issue 3, Page(s) 151–152

    Language English
    Publishing date 2017-05-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2048635-2
    ISSN 1531-0043
    ISSN 1531-0043
    DOI 10.1055/s-0037-1598153
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Editorial: 'The giant's shoulders': understanding Michael Rutter's impact on science and society.

    Sonuga-Barke, Edmund / Fearon, Pasco / Scott, Stephen

    Journal of child psychology and psychiatry, and allied disciplines

    2021  Volume 63, Issue 1, Page(s) 1–3

    Abstract: The recent death of our colleague and friend Professor Sir Michael Rutter has quite rightly been ...

    Abstract The recent death of our colleague and friend Professor Sir Michael Rutter has quite rightly been greeted by an outpouring of gratitude and respect from distinguished commentators across the globe working in diverse fields of the basic, social and clinical sciences as well as from clinicians and policy makers. These have without exception highlighted his seminal role as a pioneer, perhaps The Pioneer, of the application of the scientific method to the study of child and adolescent mental health and disorder - the father of evidence-based Child Psychiatry and the most influential voice in the new field of Developmental Psychopathology (Stevenson, 2022). In this editorial, we will attempt to build on these commentaries. We will parse Mike's scientific contributions to our field, in order to identify the personal characteristics and intellectual modus operandi that made him such a uniquely important figure, whose influence will resonate through the many fields he influenced for decades to come. We will also attempt something of a reframing of that contribution. Our thesis being that, although he never agitated for it politically or even stated it as a goal explicitly, Mike's work was motivated by a desire for social reform and created the scientific catalyst for such reform to occur.
    MeSH term(s) Adolescent ; Child ; Family ; Humans ; Male ; Shoulder
    Language English
    Publishing date 2021-12-22
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 218136-8
    ISSN 1469-7610 ; 0021-9630 ; 0373-8086
    ISSN (online) 1469-7610
    ISSN 0021-9630 ; 0373-8086
    DOI 10.1111/jcpp.13558
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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