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  1. Article: Search for the rare decays B-->Kl(+)l(-) and B-->K(*)l(+)l(-).

    Aubert, B / Boutigny, D / Gaillard, J-M / Hicheur, A / Karyotakis, Y / Lees, J P / Robbe, P / Tisserand, V / Palano, A / Pompili, A / Chen, G P / Chen, J C / Qi, N D / Rong, G / Wang, P / Zhu, Y S / Eigen, G / Stugu, B / Abrams, G S /
    Borgland, A W / Breon, A B / Brown, D N / Button-Shafer, J / Cahn, R N / Clark, A R / Gill, M S / Gritsan, A V / Groysman, Y / Jacobsen, R G / Kadel, R W / Kadyk, J / Kerth, L T / Kolomensky, Yu G / Kral, J F / LeClerc, C / Levi, M E / Lynch, G / Oddone, P J / Pripstein, M / Roe, N A / Romosan, A / Ronan, M T / Shelkov, V G / Telnov, A V / Wenzel, W A / Harrison, T J / Hawkes, C M / Knowles, D J / O'Neale, S W / Penny, R C / Watson, A T / Watson, N K / Deppermann, T / Goetzen, K / Koch, H / Kunze, M / Lewandowski, B / Peters, K / Schmuecker, H / Steinke, M / Barlow, N R / Bhimji, W / Chevalier, N / Clark, P J / Cottingham, W N / Foster, B / Mackay, C / Wilson, F F / Abe, K / Hearty, C / Mattison, T S / McKenna, J A / Thiessen, D / Jolly, S / McKemey, A K / Blinov, V E / Bukin, A D / Bukin, D A / Buzykaev, A R / Golubev, V B / Ivanchenko, V N / Korol, A A / Kravchenko, E A / Onuchin, A P / Serednyakov, S I / Skovpen, Yu I / Telnov, V I / Yushkov, A N / Best, D / Chao, M / Kirkby, D / Lankford, A J / Mandelkern, M / McMahon, S / Stoker, D P / Arisaka, K / Buchanan, C / Chun, S / MacFarlane, D B / Prell, S / Rahatlou, Sh / Raven, G / Sharma, V / Campagnari, C / Dahmes, B / Hart, P A / Kuznetsova, N / Levy, S L / Long, O / Lu, A / Richman, J D / Verkerke, W / Beringer, J / Eisner, A M / Grothe, M / Heusch, C A / Lockman, W S / Pulliam, T / Schalk, T / Schmitz, R E / Schumm, B A / Seiden, A / Turri, M / Walkowiak, W / Williams, D C / Wilson, M G / Chen, E / Dubois-Felsmann, G P / Dvoretskii, A / Hitlin, D G / Metzler, S / Oyang, J / Porter, F C / Ryd, A / Samuel, A / Weaver, M / Yang, S / Zhu, R Y / Devmal, S / Geld, T L / Jayatilleke, S / Mancinelli, G / Meadows, B T / Sokoloff, M D / Barillari, T / Bloom, P / Dima, M O / Ford, W T / Nauenberg, U / Olivas, A / Rankin, P / Roy, J / Smith, J G / van Hoek, W C / Blouw, J / Harton, J L / Krishnamurthy, M / Soffer, A / Toki, W H / Wilson, R J / Zhang, J / Brandt, T / Brose, J / Colberg, T / Dickopp, M / Dubitzky, R S / Hauke, A / Maly, E / Müller-Pfefferkorn, R / Otto, S / Schubert, K R / Schwierz, R / Spaan, B / Wilden, L / Bernard, D / Bonneaud, G R / Brochard, F / Cohen-Tanugi, J / Ferrag, S / T'Jampens, S / Thiebaux, Ch / Vasileiadis, G / Verderi, M / Anjomshoaa, A / Bernet, R / Khan, A / Lavin, D / Muheim, F / Playfer, S / Swain, J E / Tinslay, J / Falbo, M / Borean, C / Bozzi, C / Dittongo, S / Piemontese, L / Treadwell, E / Anulli, F / Baldini-Ferroli, R / Calcaterra, A / de Sangro, R / Falciai, D / Finocchiaro, G / Patteri, P / Peruzzi, I M / Piccolo, M / Xie, Y / Zallo, A / Bagnasco, S / Buzzo, A / Contri, R / Crosetti, G / Lo Vetere, M / Macri, M / Monge, M R / Passaggio, S / Pastore, F C / Patrignani, C / Pia, M G / Robutti, E / Santroni, A / Tosi, S / Morii, M / Bartoldus, R / Hamilton, R / Mallik, U / Cochran, J / Crawley, H B / Fischer, P-A / Lamsa, J / Meyer, W T / Rosenberg, E I / Grosdidier, G / Hast, C / Höcker, A / Lacker, H M / Laplace, S / Lepeltier, V / Lutz, A M / Plaszczynski, S / Schune, M H / Trincaz-Duvoid, S / Wormser, G / Bionta, R M / Brigljević, V / Lange, D J / Mugge, M / van Bibber, K / Wright, D M / Bevan, A J / Fry, J R / Gabathuler, E / Gamet, R / George, M / Kay, M / Payne, D J / Sloane, R J / Touramanis, C / Aspinwall, M L / Bowerman, D A / Dauncey, P D / Egede, U / Eschrich, I / Gunawardane, N J W / Nash, J A / Sanders, P / Smith, D / Azzopardi, D E / Back, J J / Bellodi, G / Dixon, P / Harrison, P F / Potter, R J L / Shorthouse, H W / Strother, P / Vidal, P B / Cowan, G / George, S / Green, M G / Kurup, A / Marker, C E / McGrath, P / McMahon, T R / Ricciardi, S / Salvatore, F / Vaitsas, G / Brown, D / Davis, C L / Allison, J / Barlow, R J / Boyd, J T / Forti, A C / Fullwood, J / Jackson, F / Lafferty, G D / Savvas, N / Weatherall, J H / Williams, J C / Farbin, A / Jawahery, A / Lillard, V / Olsen, J / Roberts, D A / Schieck, J R / Blaylock, G / Dallapiccola, C / Flood, K T / Hertzbach, S S / Kofler, R / Koptchev, V B / Moore, T B / Staengle, H / Willocq, S / Brau, B / Cowan, R / Sciolla, G / Taylor, F / Yamamoto, R K / Milek, M / Patel, P M / Palombo, F / Bauer, J M / Cremaldi, L / Eschenburg, V / Kroeger, R / Reidy, J / Sanders, D A / Summers, D J / Nief, J Y / Taras, P / Nicholson, H / Cartaro, C / Cavallo, N / De Nardo, G / Fabozzi, F / Gatto, C / Lista, L / Paolucci, P / Piccolo, D / Sciacca, C / LoSecco, J M / Alsmiller, J R G / Gabriel, T A / Brau, J / Frey, R / Grauges, E / Iwasaki, M / Sinev, N B / Strom, D / Colecchia, F / Dal Corso, F / Dorigo, A / Galeazzi, F / Margoni, M / Michelon, G / Morandin, M / Posocco, M / Rotondo, M / Simonetto, F / Stroili, R / Torassa, E / Voci, C / Benayoun, M / Briand, H / Chauveau, J / David, P / de la Vaissière, Ch / Del Buono, L / Hamon, O / Le Diberder, F / Leruste, Ph / Ocariz, J / Roos, L / Stark, J / Manfredi, P F / Re, V / Speziali, V / Frank, E D / Gladney, L / Guo, Q H / Panetta, J / Angelini, C / Batignani, G / Bettarini, S / Bondioli, M / Bucci, F / Campagna, E / Carpinelli, M / Forti, F / Giorgi, M A / Lusiani, A / Marchiori, G / Martinez-Vidal, F / Morganti, M / Neri, N / Paoloni, E / Rama, M / Rizzo, G / Sandrelli, F / Simi, G / Triggiani, G / Walsh, J / Haire, M / Judd, D / Paick, K / Turnbull, L / Wagoner, D E / Albert, J / Elmer, P / Lu, C / Miftakov, V / Schaffner, S F / Smith, A J S / Tumanov, A / Varnes, E W / Cavoto, G / del Re, D / Faccini, R / Ferrarotto, F / Ferroni, F / Lamanna, E / Mazzoni, M A / Morganti, S / Piredda, G / Safai Tehrani, F / Serra, M / Voena, C / Christ, S / Waldi, R / Adye, T / De Groot, N / Franek, B / Geddes, N I / Gopal, G P / Xella, S M / Aleksan, R / Emery, S / Gaidot, A / Ganzhur, S F / Giraud, P-F / Hamel de Monchenault, G / Kozanecki, W / Langer, M / London, G W / Mayer, B / Serfass, B / Vasseur, G / Yèche, Ch / Zito, M / Purohit, M V / Singh, H / Weidemann, A W / Yumiceva, F X / Adam, I / Aston, D / Berger, N / Boyarski, A M / Calderini, G / Convery, M R / Coupal, D P / Dong, D / Dorfan, J / Dunwoodie, W / Field, R C / Glanzman, T / Gowdy, S J / Haas, T / Himel, T / Hryn'ova, T / Huffer, M E / Innes, W R / Jessop, C P / Kelsey, M H / Kim, P / Kocian, M L / Langenegger, U / Leith, D W G S / Luitz, S / Luth, V / Lynch, H L / Marsiske, H / Menke, S / Messner, R / Muller, D R / O'Grady, C P / Ozcan, V E / Perazzo, A / Perl, M / Petrak, S / Quinn, H / Ratcliff, B N / Robertson, S H / Roodman, A / Salnikov, A A / Schietinger, T / Schindler, R H / Schwiening, J / Snyder, A / Soha, A / Spanier, S M / Stelzer, J / Su, D / Sullivan, M K / Tanaka, H A / Va'vra, J / Wagner, S R / Weinstein, A J R / Wisniewski, W J / Wright, D H / Young, C C / Burchat, P R / Cheng, C H / Meyer, T I / Roat, C / Henderson, R / Bugg, W / Cohn, H / Izen, J M / Kitayama, I / Lou, X C / Bianchi, F / Bona, M / Gamba, D / Bosisio, L / Della Ricca, G / Lanceri, L / Poropat, P / Vuagnin, G / Panvini, R S / Brown, C M / Jackson, P D / Kowalewski, R / Roney, J M / Band, H R / Charles, E / Dasu, S / Eichenbaum, A M / Hu, H / Johnson, J R / Liu, R / Di Lodovico, F / Pan, Y / Prepost, R / Scott, I J / Sekula, S J / von Wimmersperg-Toeller, J H / Wu, S L / Yu, Z / Kordich, T M B / Neal, H

    Physical review letters

    2002  Volume 88, Issue 24, Page(s) 241801

    Abstract: ... K(*)l(+)l(-), where l(+)l(-) is either an e(+)e(-) or mu(+)mu(-) pair. The data sample comprises 22 ... We obtain the 90% C.L. upper limits B(B-->Kl(+)l(-))<0.51 x 10(-6) and B(B-->K(*)l(+)l(-))<3.1 x 10(-6 ... We present results from a search for the flavor-changing neutral current decays B-->Kl(+)l(-) and B ...

    Abstract We present results from a search for the flavor-changing neutral current decays B-->Kl(+)l(-) and B-->K(*)l(+)l(-), where l(+)l(-) is either an e(+)e(-) or mu(+)mu(-) pair. The data sample comprises 22.7 x 10(6) Upsilon(4S)-->B(-)B decays collected with the BABAR detector at the PEP-II B Factory. We obtain the 90% C.L. upper limits B(B-->Kl(+)l(-))<0.51 x 10(-6) and B(B-->K(*)l(+)l(-))<3.1 x 10(-6), close to standard model predictions for these branching fractions. We have also obtained limits on the lepton-family-violating decays B-->Ke+/-mu(-/+) and B-->K(*)e(+/-)mu(-/+).
    Language English
    Publishing date 2002-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.88.241801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The endogenous brain constituent N-arachidonoyl L-serine is an activator of large conductance Ca2+-activated K+ channels.

    Godlewski, Grzegorz / Offertáler, László / Osei-Hyiaman, Douglas / Mo, Fong Ming / Harvey-White, Judith / Liu, Jie / Davis, Margaret I / Zhang, Li / Razdan, Raj K / Milman, Garry / Pacher, Pal / Mukhopadhyay, Partha / Lovinger, David M / Kunos, George

    The Journal of pharmacology and experimental therapeutics

    2008  Volume 328, Issue 1, Page(s) 351–361

    Abstract: The novel endocannabinoid-like lipid N-arachidonoyl L-serine (ARA-S) causes ... vascular preparations and its effects on Ca(2+)-activated K(+) currents in human embryonic kidney cells ... stably transfected with the alpha-subunit of the human, large conductance Ca(+)-activated K(+) (BK(Ca ...

    Abstract The novel endocannabinoid-like lipid N-arachidonoyl L-serine (ARA-S) causes vasodilation through both endothelium-dependent and -independent mechanisms. We have analyzed the vasorelaxant effect of ARA-S in isolated vascular preparations and its effects on Ca(2+)-activated K(+) currents in human embryonic kidney cells stably transfected with the alpha-subunit of the human, large conductance Ca(+)-activated K(+) (BK(Ca)) channel [human embryonic kidney (HEK) 293hSlo cells]. ARA-S caused relaxation of rat isolated, intact and denuded, small mesenteric arteries preconstricted with (R)-(-)-1-(3-hydroxyphenyl)-2-methylaminoethanol hydrochloride (pEC(50), 5.49 and 5.14, respectively), whereas it caused further contraction of vessels preconstricted with KCl (pEC(50), 5.48 and 4.82, respectively). Vasorelaxation by ARA-S was inhibited by 100 nM iberiotoxin. In human embryonic kidney cells stably transfected with the alpha-subunit of the human BK(Ca) channel cells, ARA-S and its enantiomer, N-arachidonoyl-D-serine, enhanced the whole-cell outward K(+) current with similar potency (pEC(50), 5.63 and 5.32, respectively). The potentiation was not altered by the beta(1) subunit or mediated by ARA-S metabolites, stimulation of known cannabinoid receptors, G proteins, protein kinases, or Ca(2+)-dependent processes; it was lost after patch excision or after membrane cholesterol depletion but was restored after cholesterol reconstitution. BK(Ca) currents were also enhanced by N-arachidonoyl ethanolamide (pEC(50), 5.27) but inhibited by another endocannabinoid, O-arachidonoyl ethanolamine (pIC(50), 6.35), or by the synthetic cannabinoid O-1918 [(-)-1,3-dimethoxy-2-(3-3,4-trans-p-menthadien-(1,8)-yl)-orcinol] (pIC(50), 6.59), which blocks ARA-S-induced vasodilation. We conclude the following. 1) ARA-S directly activates BK(Ca) channels. 2) This interaction does not involve cannabinoid receptors or cytosolic factors but is dependent on the presence of membrane cholesterol. 3) Direct BK(Ca) channel activation probably contributes to the endothelium-independent component of ARA-S-induced mesenteric vasorelaxation. 4) O-1918 is a BK(Ca) channel inhibitor.
    MeSH term(s) Alternative Splicing ; Animals ; Arachidonic Acids/physiology ; Brain/physiology ; Cell Line ; Genetic Variation ; Humans ; Kidney/enzymology ; Large-Conductance Calcium-Activated Potassium Channels/genetics ; Large-Conductance Calcium-Activated Potassium Channels/physiology ; Male ; Membrane Potentials/physiology ; Patch-Clamp Techniques ; Rats ; Rats, Sprague-Dawley ; Serine/analogs & derivatives ; Serine/physiology
    Chemical Substances Arachidonic Acids ; Large-Conductance Calcium-Activated Potassium Channels ; N-arachidonoyl L-serine ; Serine (452VLY9402)
    Language English
    Publishing date 2008-10-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 3106-9
    ISSN 1521-0103 ; 0022-3565
    ISSN (online) 1521-0103
    ISSN 0022-3565
    DOI 10.1124/jpet.108.144717
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Diabetic Foot Considerations Related to Plantar Pressures and Shear.

    Martin, Jessi K / Davis, Brian L

    Foot and ankle clinics

    2023  Volume 28, Issue 1, Page(s) 13–25

    Abstract: Diabetic foot ulcers are a complex, multifaceted, and widespread complication of diabetes mellitus. Although there are a multitude of risk factors contributing to diabetic foot ulcer development, pressure and (more recently) shear stresses are two ... ...

    Abstract Diabetic foot ulcers are a complex, multifaceted, and widespread complication of diabetes mellitus. Although there are a multitude of risk factors contributing to diabetic foot ulcer development, pressure and (more recently) shear stresses are two biomechanical metrics that are gaining popularity for monitoring risk factors predisposing skin breakdown. Other areas of diabetic foot ulcers under research include plantar temperature measuring, as well as monitoring wear-time compliance and machine learning/AI algorithms. Charcot arthropathy is another diabetes complication that has a relationship with diabetic foot ulcer development, which should be monitored for development alongside ulcer development. The ability to monitor and prevent diabetic foot ulcer development and Charcot neuroarthropathy will lead to increased patient outcomes and patient quality of life.
    MeSH term(s) Humans ; Diabetic Foot/complications ; Quality of Life ; Arthropathy, Neurogenic ; Risk Factors ; Diabetes Mellitus
    Language English
    Publishing date 2023-01-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2051688-5
    ISSN 1558-1934 ; 1083-7515
    ISSN (online) 1558-1934
    ISSN 1083-7515
    DOI 10.1016/j.fcl.2022.11.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Some young adults hyper-bind too: Attentional control relates to individual differences in hyper-binding.

    Davis, Emily E / Tehrani, Edyta K / Campbell, Karen L

    Psychonomic bulletin & review

    2024  

    Abstract: Hyper-binding - the erroneous encoding of target and distractor information into associative pairs in memory - has been described as a unique age effect caused by declines in attentional control. Previous work has found that, on average, young adults do ... ...

    Abstract Hyper-binding - the erroneous encoding of target and distractor information into associative pairs in memory - has been described as a unique age effect caused by declines in attentional control. Previous work has found that, on average, young adults do not hyper-bind. However, if hyper-binding is caused by reduced attentional control, then young adults with poor attention regulation should also show evidence of hyper-binding. We tested this question with an individual differences approach, using a battery of attentional control tasks and relating this to individual differences in hyper-binding. Participants (N = 121) completed an implicit associative memory test measuring memory for both target-distractor (i.e., hyper-binding) and target-target pairs, followed by a series of tasks measuring attentional control. Our results show that on average, young adults do not hyper-bind, but as predicted, those with poor attentional control show a larger hyper-binding effect than those with good attentional control. Exploratory analyses also suggest that individual differences in attentional control relate to susceptibility to interference at retrieval. These results support the hypothesis that hyper-binding in older adults is due to age-related declines in attentional control, and demonstrate that hyper-binding may be an issue for any individual with poor attentional control, regardless of age.
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2031311-1
    ISSN 1531-5320 ; 1069-9384
    ISSN (online) 1531-5320
    ISSN 1069-9384
    DOI 10.3758/s13423-024-02464-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Metabolic activation of racemic and enantiomeric trans-8, 9-dihydroxy-8,9-dihydrodibenzo[a,l]pyrene (dibenzo[def,p]chrysene) to dibenzo[a,l]pyrene-bis-dihydrodiols by induced rat liver microsomes and a recombinant human P450 1A1 system: the role of the K-region-derived metabolic intermediates in the formation of dibenzo[a,l]pyrene-DNA adducts.

    Nesnow, S / Davis, C / Padgett, W / George, M / Lambert, G / Meyers, F / Allison, J / Adams, L / King, L C

    Chemical research in toxicology

    1998  Volume 11, Issue 12, Page(s) 1596–1607

    Abstract: Metabolic activation studies of dibenzo[a,l]pyrene (DB[a,l]P) (dibenzo[def,p]chrysene ... associated with high mutagenic and carcinogenic activities of the corresponding fjord-region DB[a,l]P-11,12 ... diol-13,14-epoxides. DB[a,l]P is metabolized by beta-naphthoflavone (BNF)- and 3-methylcholanthrene ...

    Abstract Metabolic activation studies of dibenzo[a,l]pyrene (DB[a,l]P) (dibenzo[def,p]chrysene), an extremely potent environmental carcinogen, have been focused on metabolism at the fjord region, a region associated with high mutagenic and carcinogenic activities of the corresponding fjord-region DB[a,l]P-11,12-diol-13,14-epoxides. DB[a,l]P is metabolized by beta-naphthoflavone (BNF)- and 3-methylcholanthrene-induced rat liver microsomes and a recombinant human P450 1A1 system to two major dihydrodiols, the K-region dihydrodiol, DB[a,l]P-8,9-dihydrodiol (DB[a,l]P-8,9-diol), and the fjord-region dihydrodiol, DB[a,l]P-11,12-dihydrodiol. We have investigated the further metabolic activation of DB[a,l]P-8,9-diol by BNF-induced rat liver microsomes and a recombinant human P450 1A1 system with epoxide hydrolase to DB[a,l]P-bis-diols and to DNA adducts. (+/-)-trans-DB[a,l]P-8,9-diol was synthesized and resolved into its enantiomers. Racemic trans-DB[a,l]P-8,9-diol was metabolized by BNF-induced rat liver microsomes to six metabolites: two diastereomers of trans,trans-DB[a,l]P-8,9:11,12-bis-diol, two diastereomers of trans,cis-DB[a,l]P-8,9:11,12-bis-diol, and two diastereomers of trans-DB[a,l]P-8,9:13,14-bis-diol as characterized by NMR, MS, and UV spectroscopy. Metabolic studies using both enantiomeric (-)- and (+)-trans-DB[a,l]P-8,9-diol further demonstrated that each diastereomer of trans,trans-DB[a,l]P-8,9:11, 12-bis-diol and trans-DB[a,l]P-8,9:13,14-bis-diol was comprised of two enantiomers. Similarly, incubations of enantiomeric or racemic trans-DB[a,l]P-8,9-diol with a recombinant human P450 1A1 system and epoxide hydrolase also gave the same two enantiomeric mixtures of diastereomers of trans,trans-DB[a,l]P-8,9:11,12-bis-diol and the same two enantiomeric mixtures of diastereomers of trans-DB[a,l]P-8, 9:13,14-bis-diol. This suggested that the microsomal oxidations of (-)- and (+)-trans-DB[a,l]P-8,9-diol were stereospecific. The stereospecific formation of enantiomers of trans-DB[a,l]P-8,9-diol from DB[a,l]P was examined using both BNF-induced rat liver microsomes and a recombinant human P450 1A1 system with epoxide hydrolase. Stereospecificity was observed as both metabolic systems favored the formation of (-)-trans-DB[a,l]P-8,9-diol by 8-9-fold. DNA adduct studies were undertaken using TLC/HPLC 32P-postlabeling techniques. In the presence of a recombinant human P450 1A1 system with epoxide hydrolase, DB[a,l]P gave two groups of calf thymus DNA adducts. The group of later-eluting adducts were identified as arising from syn- and anti-DB[a,l]P-11,12-diol-13,14-epoxides, while the more polar early-eluting adducts were derived, in part, from the further activation of trans-DB[a,l]P-8,9-diol. Our data indicate that, in P450 1A1-mediated microsomal incubations, DB[a,l]P is metabolized to trans-DB[a,l]P-8,9-diol which is further metabolized to DB[a,l]P-bis-diols. trans-DB[a,l]P-8,9-diol is metabolically activated to intermediates that can bind to DNA and give DNA adducts similar to those observed with DB[a,l]P. These results indicate that DB[a,l]P can be metabolically activated by both fjord-region and K-region pathways.
    MeSH term(s) Animals ; Benzopyrenes/chemistry ; Benzopyrenes/pharmacokinetics ; Biotransformation ; Carcinogens/chemistry ; Cattle ; Chromatography, High Pressure Liquid ; Circular Dichroism ; Cytochrome P-450 CYP1A1/metabolism ; DNA Adducts/chemistry ; Dihydroxydihydrobenzopyrenes/pharmacokinetics ; Magnetic Resonance Spectroscopy ; Male ; Microsomes, Liver/metabolism ; Models, Molecular ; Rats ; Recombinant Proteins/chemistry ; Spectrophotometry, Ultraviolet ; Stereoisomerism
    Chemical Substances Benzopyrenes ; Carcinogens ; DNA Adducts ; Dihydroxydihydrobenzopyrenes ; Recombinant Proteins ; Cytochrome P-450 CYP1A1 (EC 1.14.14.1) ; dibenzo(a,l)pyrene (G3X629VE4A)
    Language English
    Publishing date 1998-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639353-6
    ISSN 1520-5010 ; 0893-228X
    ISSN (online) 1520-5010
    ISSN 0893-228X
    DOI 10.1021/tx9801561
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: 113 The effects of bisphenols on cryopreserved bovine spermatozoa

    Davis, O / Hickey, K / Favetta, L

    Reproduction, fertility, and development

    2022  Volume 34, Issue 2, Page(s) 293–294

    Language English
    Publishing date 2022-03-01
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1019913-5
    ISSN 1448-5990 ; 1031-3613
    ISSN (online) 1448-5990
    ISSN 1031-3613
    DOI 10.1071/RDv34n2Ab113
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  7. Article: Key to the North American tribes and genera of herb, rose, bramble, and inquiline gall wasps (Hymenoptera, Cynipoidea, Cynipidae

    Nastasi, Louis F / Buffington, Matthew L / Davis, Charles K / Deans, Andrew R

    ZooKeys

    2024  Volume 1196, Page(s) 177–207

    Abstract: Robust keys exist for the family-level groups of Cynipoidea. However, for most regions of the world, keys to genera are not available. To address this gap as it applies to North America, a fully illustrated key is provided to facilitate identification of ...

    Abstract Robust keys exist for the family-level groups of Cynipoidea. However, for most regions of the world, keys to genera are not available. To address this gap as it applies to North America, a fully illustrated key is provided to facilitate identification of the tribes and genera of rose gall, herb gall, and inquiline gall wasps known from the region. For each taxon covered, a preliminary diagnosis and an updated overview of taxonomy, biology, distribution, and natural history are provided.
    Language English
    Publishing date 2024-03-25
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2445640-8
    ISSN 1313-2970 ; 1313-2989
    ISSN (online) 1313-2970
    ISSN 1313-2989
    DOI 10.3897/zookeys.1196.118460
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  8. Article ; Online: Event boundaries structure the contents of long-term memory in younger and older adults.

    Davis, E E / Campbell, K L

    Memory (Hove, England)

    2022  Volume 31, Issue 1, Page(s) 47–60

    Abstract: ... Recently, this effect was observed in both young and old adults using movie stimuli (Davis, Chemnitz, et al ...

    Abstract Event boundaries impose structure on how events are stored in long-term memory. Research with young adults has shown that associations within events are stronger than those that cross event boundaries. Recently, this effect was observed in both young and old adults using movie stimuli (Davis, Chemnitz, et al., 2021). Here, we test whether this effect extends to written narratives. Young and old participants read a series of narratives that were interspersed with temporal shifts in the storyline meant to elicit the perception of an event boundary. Later, participants were cued with sentences and were asked to recall the sentence that immediately followed. We expected participants would have worse memory when a cue and correct answer flanked a boundary than when it did not. In Experiment 1, we found that despite older adults' lower performance overall, both age groups had lower accuracy for cues that flanked a boundary, compared to cues that elicited a response from within the same event. Experiment 2 replicated the results from Experiment 1. Our results support past work that did not find age differences in event perception and demonstrate that older and younger adults may store events similarly in long-term memory.
    MeSH term(s) Young Adult ; Humans ; Aged ; Memory, Long-Term/physiology ; Mental Recall/physiology ; Cues ; Language ; Memory Disorders ; Aging/physiology
    Language English
    Publishing date 2022-09-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1147478-6
    ISSN 1464-0686 ; 0965-8211
    ISSN (online) 1464-0686
    ISSN 0965-8211
    DOI 10.1080/09658211.2022.2122998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The disproportionate impact of peer learning on emergency radiology.

    Czerminski, Jan / Pahade, Jay K / Davis, Melissa A / Mezrich, Jonathan L

    Emergency radiology

    2024  Volume 31, Issue 2, Page(s) 133–139

    Abstract: Purpose: The use of peer learning methods in radiology continues to grow as a means to constructively learn from past mistakes. This study examined whether emergency radiologists receive a disproportionate amount of peer learning feedback entered as ... ...

    Abstract Purpose: The use of peer learning methods in radiology continues to grow as a means to constructively learn from past mistakes. This study examined whether emergency radiologists receive a disproportionate amount of peer learning feedback entered as potential learning opportunities (PLO), which could play a significant role in stress and career satisfaction. Our institution offers 24/7 attending coverage, with emergency radiologists interpreting a wide range of X-ray, ultrasound and CT exams on both adults and pediatric patients.
    Materials and methods: Peer learning submissions entered as PLO at a single large academic medical center over a span of 3 years were assessed by subspecialty distribution and correlated with the number of attending radiologists in each section. Total number of studies performed on emergency department patients and throughout the hospital system were obtained for comparison purposes. Data was assessed using analysis of variance and post hoc analysis.
    Results: Emergency radiologists received significantly more (2.5 times) PLO submissions than the next closest subspeciality division and received more yearly PLO submissions per attending compared to other subspeciality divisions. This was found to still be true when normalizing for increased case volumes; Emergency radiologists received more PLO submissions per 1000 studies compared to other divisions in our department (1.59 vs. 0.85, p = 0.04).
    Conclusion: Emergency radiologists were found to receive significantly more PLO submissions than their non-emergency colleagues. Presumed causes for this discrepancy may include a higher error rate secondary to wider range of studies interpreted, demand for shorter turn-around times, higher volumes of exams read per shift, and hindsight bias in the setting of follow-up review.
    MeSH term(s) Humans ; Child ; Radiology/education ; Radiologists ; Clinical Competence ; Academic Medical Centers
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1425144-9
    ISSN 1438-1435 ; 1070-3004
    ISSN (online) 1438-1435
    ISSN 1070-3004
    DOI 10.1007/s10140-024-02207-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Micellular fluorescence resonance energy transfer based fluorescent ratiometric response to hydrocarbon analytes.

    Gordon, Calum K / Nass, Liselotte / Chan, Sanutep / Davis, Nathaniel J L K

    Luminescence : the journal of biological and chemical luminescence

    2023  

    Abstract: Fluorescence resonance energy transfer (FRET) has been utilised to develop numerous selective and sensitive fluorescent ratiometric sensors. Typically, FRET-based fluorescent ratiometric sensors rely on chemical interactions between the sensor and ... ...

    Abstract Fluorescence resonance energy transfer (FRET) has been utilised to develop numerous selective and sensitive fluorescent ratiometric sensors. Typically, FRET-based fluorescent ratiometric sensors rely on chemical interactions between the sensor and analyte to illicit a response, thus unreactive hydrocarbons are a neglected analyte and a source for new sensors. By containing an unbound donor-acceptor system within micelles, energy transfer is enabled by spatial confinement. This offers the potential of a ratiometric response as a hydrocarbon analyte is added. Introducing a hydrocarbon analyte to this system causes micelles to swell, increasing the donor-acceptor distance and thus reducing the amount of observed energy transfer. We present InP/ZnS quantum dot donors interacting with a Nile Red acceptor, confined by cetyltrimethylammonium bromide (CTAB)-based micelles. We alleviated spatial confinement of the pair within micelles using common laboratory solvents to represent hydrocarbons, (toluene, hexane and octadecene). We constructed calibration curves for each solvent and found effective sensing ranges of 0.009-0.21, 0.008-0.27 and 0.003-0.06 M for toluene, hexane and octadecene, respectively. This study contributes towards the development of new hydrocarbon sensors utilising this new mechanism.
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1470995-8
    ISSN 1522-7243 ; 1522-7235 ; 1099-1271
    ISSN (online) 1522-7243
    ISSN 1522-7235 ; 1099-1271
    DOI 10.1002/bio.4653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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