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  1. Book ; Online ; E-Book: Pathophysiologic basis of acid-base disorders

    Habibzadeh, Farrokh / Habibzadeh, Parham / Yadollahie, Mahboobeh

    2021  

    Author's details Farrokh Habibzadeh, Mahboobeh Yadollahie, Parham Habibzadeh
    Keywords Internal medicine ; Desequilibri àcid-base ; Fisiologia patològica
    Subject code 616
    Language English
    Size 1 online resource (157 pages)
    Publisher Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-16-0526-2 ; 981-16-0525-4 ; 978-981-16-0526-0 ; 978-981-16-0525-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: The apparent prevalence, the true prevalence.

    Habibzadeh, Farrokh / Habibzadeh, Parham / Yadollahie, Mahboobeh

    Biochemia medica

    2022  Volume 32, Issue 2, Page(s) 20101

    Abstract: Serologic tests are important for conducting seroepidemiologic and prevalence studies. However, the tests used are typically imperfect and produce false-positive and false-negative results. This is why the seropositive rate (apparent prevalence) does not ...

    Abstract Serologic tests are important for conducting seroepidemiologic and prevalence studies. However, the tests used are typically imperfect and produce false-positive and false-negative results. This is why the seropositive rate (apparent prevalence) does not typically reflect the true prevalence of the disease or condition of interest. Herein, we discuss the way the true prevalence could be derived from the apparent prevalence and test sensitivity and specificity. A computer simulation based on the Monte-Carlo algorithm was also used to further examine a situation where the measured test sensitivity and specificity are also uncertain. We then complete our review with a real example. The apparent prevalence observed in many prevalence studies published in medical literature is a biased estimation and cannot be interpreted correctly unless we correct the value.
    MeSH term(s) Computer Simulation ; Humans ; Prevalence ; Sensitivity and Specificity ; Seroepidemiologic Studies ; Serologic Tests
    Language English
    Publishing date 2022-07-05
    Publishing country Croatia
    Document type Journal Article ; Review
    ZDB-ID 1208725-7
    ISSN 1846-7482 ; 1330-0962
    ISSN (online) 1846-7482
    ISSN 1330-0962
    DOI 10.11613/BM.2022.020101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: On Measuring Vaccine Effectiveness with Observational Study Designs.

    Habibzadeh, Farrokh / Habibzadeh, Parham / Yadollahie, Mahboobeh

    Acta medica academica

    2022  Volume 51, Issue 2, Page(s) 134–146

    Abstract: Herein, we present a bird's eye view of common observational study designs utilized for measurement of vaccine effectiveness. Assessing vaccines effectiveness is an integral part of vaccine research, particularly for the newly developed vaccines. A ... ...

    Abstract Herein, we present a bird's eye view of common observational study designs utilized for measurement of vaccine effectiveness. Assessing vaccines effectiveness is an integral part of vaccine research, particularly for the newly developed vaccines. A cohort study is prospective, directing from an exposure to one or more outcomes. The design is the best method to ascertain the attack rate of an infectious disease. A traditional case-control study is retrospective, directing from a given outcome to one or more exposures. The design cannot provide the relative risk, but it can provide the odds ratio, which is a good estimation of the relative risk when the attack rate is low. Critically depending on laboratory test results and performance, the test-negative case-control study design is another type of observational study commonly used nowadays for the evaluation of the vaccine effectiveness. Comparing to cohort and traditional case-control designs, conducting a test-negative case-control study is relatively cheaper and faster. Herein, we describe each of the above-mentioned study designs through examples generated by a Monte-Carlo simulation program assuming real-world conditions. CONCLUSION: The simulation shows that regardless of the study design employed, the diagnostic test specificity is of utmost importance in providing a valid estimate of the vaccine effectiveness.
    MeSH term(s) Humans ; Case-Control Studies ; Cohort Studies ; Retrospective Studies ; Prospective Studies ; Vaccine Efficacy ; Vaccines
    Chemical Substances Vaccines
    Language English
    Publishing date 2022-10-31
    Publishing country Bosnia and Herzegovina
    Document type Observational Study ; Journal Article
    ZDB-ID 2558604-X
    ISSN 1840-2879 ; 1840-2879
    ISSN (online) 1840-2879
    ISSN 1840-2879
    DOI 10.5644/ama2006-124.383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Looking for the remedies.

    Habibzadeh, Parham

    Emergency medicine Australasia : EMA

    2016  Volume 28, Issue 1, Page(s) 121

    MeSH term(s) Humans ; Periodicals as Topic
    Language English
    Publishing date 2016-02
    Publishing country Australia
    Document type Comment ; Letter
    ZDB-ID 2161824-0
    ISSN 1742-6723 ; 1742-6731 ; 1035-6851
    ISSN (online) 1742-6723
    ISSN 1742-6731 ; 1035-6851
    DOI 10.1111/1742-6723.12517
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sanctions on Health Education.

    Habibzadeh, Parham

    Archives of Iranian medicine

    2016  Volume 19, Issue 8, Page(s) 610

    MeSH term(s) Education, Medical, Continuing/methods ; Human Rights ; Humans ; Internet/utilization ; Iran ; Public Policy
    Language English
    Publishing date 2016-08
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2204979-4
    ISSN 1735-3947 ; 1029-2977
    ISSN (online) 1735-3947
    ISSN 1029-2977
    DOI 0161908/AIM.0016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Our red?green world.

    Habibzadeh, Parham

    Australian health review : a publication of the Australian Hospital Association

    2015  

    Language English
    Publishing date 2015-10-19
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 639155-2
    ISSN 0156-5788 ; 0159-5709
    ISSN 0156-5788 ; 0159-5709
    DOI 10.1071/AH15161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Are current archiving systems reliable enough?

    Habibzadeh, Parham

    International urogynecology journal

    2015  Volume 26, Issue 10, Page(s) 1553

    MeSH term(s) Internet ; Publishing/standards
    Language English
    Publishing date 2015-10
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 1050631-7
    ISSN 1433-3023 ; 0937-3462
    ISSN (online) 1433-3023
    ISSN 0937-3462
    DOI 10.1007/s00192-015-2805-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The likelihood ratio and its graphical representation.

    Habibzadeh, Farrokh / Habibzadeh, Parham

    Biochemia medica

    2019  Volume 29, Issue 2, Page(s) 20101

    Abstract: Diagnostic tests are important clinical tools. Bayes' theorem and Bayesian approach are important methods for interpreting test results. The Bayesian factor, the so-called likelihood ratio, has not always been well-understood. In this article, we try to ... ...

    Abstract Diagnostic tests are important clinical tools. Bayes' theorem and Bayesian approach are important methods for interpreting test results. The Bayesian factor, the so-called likelihood ratio, has not always been well-understood. In this article, we try to discuss the likelihood ratio and its value for a specific test result, a positive or negative test result, and a range of test results, along with their graphical representations.
    MeSH term(s) Bayes Theorem ; Computer Graphics ; Data Interpretation, Statistical ; Diagnostic Tests, Routine ; Humans
    Language English
    Publishing date 2019-04-15
    Publishing country Croatia
    Document type Journal Article ; Review
    ZDB-ID 1208725-7
    ISSN 1846-7482 ; 1330-0962
    ISSN (online) 1846-7482
    ISSN 1330-0962
    DOI 10.11613/BM.2019.020101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: On the information hidden in a classifier distribution.

    Habibzadeh, Farrokh / Habibzadeh, Parham / Yadollahie, Mahboobeh / Roozbehi, Hooman

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 917

    Abstract: Classification tasks are a common challenge to every field of science. To correctly interpret the results provided by a classifier, we need to know the performance indices of the classifier including its sensitivity, specificity, the most appropriate cut- ...

    Abstract Classification tasks are a common challenge to every field of science. To correctly interpret the results provided by a classifier, we need to know the performance indices of the classifier including its sensitivity, specificity, the most appropriate cut-off value (for continuous classifiers), etc. Typically, several studies should be conducted to find all these indices. Herein, we show that they already exist, hidden in the distribution of the variable used to classify, and can readily be harvested. An educated guess about the distribution of the variable used to classify in each class would help us to decompose the frequency distribution of the variable in population into its components-the probability density function of the variable in each class. Based on the harvested parameters, we can then calculate the performance indices of the classifier. As a case study, we applied the technique to the relative frequency distribution of prostate-specific antigen, a biomarker commonly used in medicine for the diagnosis of prostate cancer. We used nonlinear curve fitting to decompose the variable relative frequency distribution into the probability density functions of the non-diseased and diseased people. The functions were then used to determine the performance indices of the classifier. Sensitivity, specificity, the most appropriate cut-off value, and likelihood ratios were calculated. The reference range of the biomarker and the prevalence of prostate cancer for various age groups were also calculated. The indices obtained were in good agreement with the values reported in previous studies. All these were done without being aware of the real health status of the individuals studied. The method is even applicable for conditions with no definite definitions (e.g., hypertension). We believe the method has a wide range of applications in many scientific fields.
    Language English
    Publishing date 2021-01-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-79548-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Predicting the outcome of asymptomatic univesicular liver hydatids: diagnostic accuracy of unenhanced CT.

    Habibzadeh, Farrokh / Habibzadeh, Parham / Shakibafard, Alireza / Saidi, Farrokh

    European radiology

    2021  Volume 31, Issue 8, Page(s) 5812–5817

    Abstract: Objectives: To establish the role of unenhanced CT in predicting the outcome of liver hydatid cysts. We sought to determine whether the presence of laminated membrane detachment (LMD) or pericyst degenerative changes (PDCs) detected on CT were reliable ... ...

    Abstract Objectives: To establish the role of unenhanced CT in predicting the outcome of liver hydatid cysts. We sought to determine whether the presence of laminated membrane detachment (LMD) or pericyst degenerative changes (PDCs) detected on CT were reliable signs for predicting a favorable outcome of liver hydatids.
    Methods: In a 20-year-long study, we prospectively followed changes occurred in CT of 106 cysts of 98 patients with incidentally discovered asymptomatic univesicular liver hydatids who accepted to enter a watch-and-wait program. An "unfavorable" outcome was defined as the occurrence of a complication (most commonly, cyst fistula or infection) or increase in the cyst size during the follow-up; otherwise, the outcome was considered "favorable." The parameters derived from a binary logistic regression analysis (with the outcome taken as the dependent variable), after appropriate transformation of the independent variables (presence of LMD or PDCs on CT), were used to calculate the sensitivity, specificity, positive and negative likelihood ratios, and positive and negative predictive values of the presence of either the abovementioned CT findings for the prediction of a favorable outcome.
    Results: The presence of LMD or PDCs had a high specificity (88%) and positive predictive value (96%) for a favorable outcome; they had high false-negative rates.
    Conclusions: The presence of either LMD or PDCs on unenhanced CT, in incidentally discovered asymptomatic univesicular liver hydatids, was associated with a high probability of a favorable outcome. Their absence does not rule out a favorable outcome.
    Key points: • Computed tomography can be used for predicting the outcome of those with incidentally discovered univesicular liver hydatids. • The presence of laminated membrane detachment and/or pericyst degenerative changes is associated with a favorable outcome. • Their absence does not necessarily indicate an unfavorable outcome.
    MeSH term(s) Cysts ; Echinococcosis, Hepatic/diagnostic imaging ; Humans ; Predictive Value of Tests ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-01-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-020-07681-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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