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  1. Article: Experimental Study of the Moisture Resistance of Cement Mortar Using Pozzolan Materials and Calcium Stearate.

    Park, Jang Hyun / Yoon, Chang Bok

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 5

    Abstract: Nanosilica and diatomite are pozzolanic resources rich in ... ...

    Abstract Nanosilica and diatomite are pozzolanic resources rich in SiO
    Language English
    Publishing date 2024-02-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17051014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Fretibacterium

    Oh, Eun Ji / Jang, Hyun Hee / Park, Sangwon / Lim, Hyun-Pil / Yun, Kwi-Dug / Jang, Woohyung / Kim, Ok-Su / Park, Chan / Won, Eun Jeong

    Annals of laboratory medicine

    2024  

    Language English
    Publishing date 2024-04-22
    Publishing country Korea (South)
    Document type Letter
    ZDB-ID 2677441-0
    ISSN 2234-3814 ; 2234-3814
    ISSN (online) 2234-3814
    ISSN 2234-3814
    DOI 10.3343/alm.2024.0043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The complete chloroplast genome sequence of

    Park, Min-Su / Cho, Won-Bum / Jang, Hyun-Do / Jang, Chang-Gee

    Mitochondrial DNA. Part B, Resources

    2022  Volume 7, Issue 2, Page(s) 336–338

    Abstract: Ligularia ... ...

    Abstract Ligularia stenocephala
    Language English
    Publishing date 2022-02-03
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2022.2032435
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  4. Article: Case report: Tolosa-Hunt syndrome-expanding the neuromyelitis optica spectrum disorder phenotype?

    Park, Soo-Hyun / Jang, Soo-Im / Lee, Eun-Ja / Kim, Nam-Hee

    Frontiers in neurology

    2024  Volume 15, Page(s) 1326867

    Abstract: Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune astrocytopathy caused by the autoantibody of aquaporin-4 (AQP4). Herein, we report a case of Tolosa-Hunt syndrome presenting with abducens palsy and AQP4 antibodies. This was a rare case of ... ...

    Abstract Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune astrocytopathy caused by the autoantibody of aquaporin-4 (AQP4). Herein, we report a case of Tolosa-Hunt syndrome presenting with abducens palsy and AQP4 antibodies. This was a rare case of AQP4-immunoglobulin G seropositivity in a patient with Tolosa-Hunt syndrome. Our findings may expand the clinical phenotype of NMOSD and indicate that clinicians should consider testing for AQP4 antibodies in patients with Tolosa-Hunt syndrome.
    Language English
    Publishing date 2024-02-14
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2024.1326867
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  5. Article ; Online: Exploring the source of ammonia generation in electrochemical nitrogen reduction using niobium nitride.

    Park, So Young / Jang, So Eun / Kim, Chang Woo / Jang, Youn Jeong / Youn, Duck Hyun

    RSC advances

    2023  Volume 13, Issue 49, Page(s) 34410–34415

    Abstract: In this study, niobium nitride (NbN) is ... ...

    Abstract In this study, niobium nitride (NbN) is prepared
    Language English
    Publishing date 2023-11-24
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra06475a
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  6. Article ; Online: Psychosocial Factors Associated with dizziness and chronic dizziness: a nationwide cross-sectional study.

    Jang, Yuna / Hur, Hyun Jung / Park, Bumhee / Park, Hye Youn

    BMC psychiatry

    2024  Volume 24, Issue 1, Page(s) 13

    Abstract: Background: Dizziness is a common symptom in adults, and chronic dizziness, such as persistent postural-perceptual dizziness, is also frequently reported and affects the quality of life of patients. This study aimed to identify psychosocial factors ... ...

    Abstract Background: Dizziness is a common symptom in adults, and chronic dizziness, such as persistent postural-perceptual dizziness, is also frequently reported and affects the quality of life of patients. This study aimed to identify psychosocial factors related to dizziness and chronic dizziness in a large-scale nationwide cohort.
    Methods: This population-based cross-sectional study used the database of the Eighth Korea National Health and Nutrition Examination Survey in 2020. Data from 4,147 adults over 40 years old were analyzed, and 1,102 adults who experienced dizziness were included in the dizziness cohort. Demographic data, medical conditions, comorbidities, functional status variables, nutritional variables and psychological variables were collected. The pattern of depressive symptoms according to the severity of dizziness was analyzed by network analysis.
    Results: The prevalence rate of dizziness was 24.6% in the general population, and chronic dizziness (≥ 3 months) developed in 210 of 1,102 (17.1%) individuals who experienced dizziness. Multiple logistic regression analysis revealed that female sex, stress, and depression were associated with dizziness. Chronic dizziness was related to tympanic abnormalities, diabetes, short sleep duration, and higher levels of stress and depression. Psychomotor retardation/agitation was a central symptom of depression in patients with chronic dizziness.
    Conclusions: This study found sex differences in factors associated with dizziness and identified psychosocial factors linked to chronic dizziness. Focusing on somatic factors rather than depressive symptoms may benefit patients with chronic dizziness.
    MeSH term(s) Adult ; Humans ; Male ; Female ; Dizziness/complications ; Dizziness/epidemiology ; Dizziness/diagnosis ; Cross-Sectional Studies ; Nutrition Surveys ; Quality of Life ; Comorbidity
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2050438-X
    ISSN 1471-244X ; 1471-244X
    ISSN (online) 1471-244X
    ISSN 1471-244X
    DOI 10.1186/s12888-023-05464-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Finely tuned ionizable lipid nanoparticles for CRISPR/Cas9 ribonucleoprotein delivery and gene editing.

    Im, San Hae / Jang, Mincheol / Park, Ji-Ho / Chung, Hyun Jung

    Journal of nanobiotechnology

    2024  Volume 22, Issue 1, Page(s) 175

    Abstract: Nonviral delivery of the CRISPR/Cas9 system provides great benefits for in vivo gene therapy due to the low risk of side effects. However, in vivo gene editing by delivering the Cas9 ribonucleoprotein (RNP) is challenging due to the poor delivery into ... ...

    Abstract Nonviral delivery of the CRISPR/Cas9 system provides great benefits for in vivo gene therapy due to the low risk of side effects. However, in vivo gene editing by delivering the Cas9 ribonucleoprotein (RNP) is challenging due to the poor delivery into target tissues and cells. Here, we introduce an effective delivery method for the CRISPR/Cas9 RNPs by finely tuning the formulation of ionizable lipid nanoparticles. The LNPs delivering CRISPR/Cas9 RNPs (CrLNPs) are demonstrated to induce gene editing with high efficiencies in various cancer cell lines in vitro. Furthermore, we show that CrLNPs can be delivered into tumor tissues with high efficiency, as well as induce significant gene editing in vivo. The current study presents an effective platform for nonviral delivery of the CRISPR/Cas9 system that can be applied as an in vivo gene editing therapeutic for treating various diseases such as cancer and genetic disorders.
    MeSH term(s) Gene Editing ; CRISPR-Cas Systems ; Cell Line ; Ribonucleoproteins/genetics ; Liposomes ; Nanoparticles
    Chemical Substances Lipid Nanoparticles ; Ribonucleoproteins ; Liposomes
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2100022-0
    ISSN 1477-3155 ; 1477-3155
    ISSN (online) 1477-3155
    ISSN 1477-3155
    DOI 10.1186/s12951-024-02427-2
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  8. Article ; Online: Overcoming challenges associated with identifying FBN1 deep intronic variants through whole-genome sequencing.

    Kim, Jee Ah / Jang, Mi-Ae / Jang, Shin Yi / Kim, Duk-Kyung / Kim, Young-Gon / Kim, Jong-Won / Park, Taek Kyu / Jang, Ja-Hyun

    Journal of clinical laboratory analysis

    2024  Volume 38, Issue 1-2, Page(s) e25009

    Abstract: Background: Marfan syndrome (MFS), caused by pathogenic variants of FBN1 (fibrillin-1), is a systemic connective tissue disorder with variable phenotypes and treatment responsiveness depending on the variant. However, a significant number of individuals ...

    Abstract Background: Marfan syndrome (MFS), caused by pathogenic variants of FBN1 (fibrillin-1), is a systemic connective tissue disorder with variable phenotypes and treatment responsiveness depending on the variant. However, a significant number of individuals with MFS remain genetically unexplained. In this study, we report novel pathogenic intronic variants in FBN1 in two unrelated families with MFS.
    Methods: We evaluated subjects with suspected MFS from two unrelated families using Sanger sequencing or multiplex ligation-dependent probe amplification of FBN1 and/or panel-based next-generation sequencing. As no pathogenic variants were identified, whole-genome sequencing was performed. Identified variants were analyzed by reverse transcription-PCR and targeted sequencing of FBN1 mRNA harvested from peripheral blood or skin fibroblasts obtained from affected probands.
    Results: We found causative deep intronic variants, c.6163+1484A>T and c.5788+36C>A, in FBN1. The splicing analysis revealed an insertion of in-frame or out-of-frame intronic sequences of the FBN1 transcript predicted to alter function of calcium-binding epidermal growth factor protein domain. Family members carrying c.6163+1484A>T had high systemic scores including prominent skeletal features and aortic dissection with lesser aortic dilatation. Family members carrying c.5788+36C>A had more severe aortic root dilatation without aortic dissection. Both families had ectopia lentis.
    Conclusion: Variable penetrance of the phenotype and negative genetic testing in MFS families should raise the possibility of deep intronic FBN1 variants and the need for additional molecular studies. This study expands the mutation spectrum of FBN1 and points out the importance of intronic sequence analysis and the need for integrative functional studies in MFS diagnosis.
    MeSH term(s) Humans ; Fibrillin-1/genetics ; Mutation/genetics ; Marfan Syndrome/genetics ; Marfan Syndrome/complications ; Marfan Syndrome/diagnosis ; Genetic Testing ; Aortic Dissection ; Aortic Diseases ; Adipokines/genetics
    Chemical Substances Fibrillin-1 ; FBN1 protein, human ; Adipokines
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645095-7
    ISSN 1098-2825 ; 0887-8013
    ISSN (online) 1098-2825
    ISSN 0887-8013
    DOI 10.1002/jcla.25009
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2471: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  9. Article ; Online: A case of primary anetoderma of Schweninger-Buzzi type.

    Seo, Hyun-Min / Jang, Jin Hyun / Park, Ji Hun / Oh, Se Uk / Kim, Joung Soo

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2023  Volume 38, Issue 4, Page(s) e346–e347

    MeSH term(s) Humans ; Anetoderma/pathology ; Skin/pathology ; Atrophy/pathology
    Language English
    Publishing date 2023-11-14
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.19610
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3492: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 413: Show issues

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  10. Article ; Online: Trophic assessment of red seabream (Pagrus major) as a possible bioindicator of human activities in the South Sea of Korea using stable C and N isotopes.

    Park, Hyun Je / Jang, Jae-Bin / Kim, Dongyoung / Kang, Hye-Eun / Song, Se Hyun / Yang, Jae-Hyeong / Kim, Hyun-Woo / Kang, Chang-Keun

    Marine pollution bulletin

    2024  Volume 200, Page(s) 116146

    Abstract: To assess the impact of sand mining on resource utilization by the red seabream (Pagrus major) and the trophic structure of fish assemblages two years after mining activities, we compared stable isotope ratios ( ... ...

    Abstract To assess the impact of sand mining on resource utilization by the red seabream (Pagrus major) and the trophic structure of fish assemblages two years after mining activities, we compared stable isotope ratios (δ
    MeSH term(s) Animals ; Humans ; Ecosystem ; Sea Bream ; Environmental Biomarkers ; Carbon Isotopes/analysis ; Sand ; Nitrogen Isotopes/analysis ; Food Chain ; Perciformes ; Fishes ; Human Activities ; Republic of Korea
    Chemical Substances Environmental Biomarkers ; Carbon Isotopes ; Sand ; Nitrogen Isotopes
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2024.116146
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