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  1. Article ; Online: [No title information]

    M Nilsson, Peter / Rydén, Lars

    Lakartidningen

    2024  Volume 121

    Title translation Polypiller rekommenderas av WHO för hjärt–kärlprevention.
    Language Swedish
    Publishing date 2024-01-18
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 391010-6
    ISSN 1652-7518 ; 0023-7205
    ISSN (online) 1652-7518
    ISSN 0023-7205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.411: Show issues Location:
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  2. Article ; Online: Into the twilight zone - should ER-low breast cancer be treated as triple negative breast cancer?

    Jernström, Helena / Rydén, Lisa

    The Lancet regional health. Europe

    2024  Volume 40, Page(s) 100896

    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article
    ISSN 2666-7762
    ISSN (online) 2666-7762
    DOI 10.1016/j.lanepe.2024.100896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Tamoxifen response in primary breast cancer

    Rydén, Lisa

    with special reference to tumour-specific VEGF-A and VEGFR2

    2007  

    Author's details Lisa Rydén
    Language English ; Swedish
    Size Getr. Zählung : Ill., graph. Darst.
    Publishing country Sweden
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Malmö, Univ., Diss., 2007
    Note Zsfassung in schwed. Sprache
    HBZ-ID HT015538597
    ISBN 91-628-6266-9 ; 978-91-628-6266-4
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2008 E 559 order for loan Magazin

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  4. Article ; Online: The 1923 Nobel Prize for the discovery of insulin in a 100-year perspective.

    Rydén, Lars / Lindsten, Magnus

    Journal of internal medicine

    2023  Volume 294, Issue 6, Page(s) 819

    Language English
    Publishing date 2023-10-20
    Publishing country England
    Document type Letter
    ZDB-ID 96274-0
    ISSN 1365-2796 ; 0954-6820
    ISSN (online) 1365-2796
    ISSN 0954-6820
    DOI 10.1111/joim.13734
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.44: Show issues Location:
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  5. Article ; Online: Parodontit – en ofta förbisedd riskfaktor för en rad sjukdomar.

    Gustafsson, Anders / Norhammar, Anna / Klinge, Björn / Rydén, Lars

    Lakartidningen

    2024  Volume 121

    Abstract: Periodontitis is a chronic inflammatory disease that degrades dental supporting tissues, including the alveolar bone. The global prevalence is 19%, in Sweden it is 11%. Left untreated, periodontitis can cause loss of teeth. The initial clinical ... ...

    Title translation Periodontitis - an often neglected risk factor for several other diseases.
    Abstract Periodontitis is a chronic inflammatory disease that degrades dental supporting tissues, including the alveolar bone. The global prevalence is 19%, in Sweden it is 11%. Left untreated, periodontitis can cause loss of teeth. The initial clinical manifestations of periodontitis usually start between 35 and 45 years of age. The underlying pathological mechanism is an aberrant inflammatory response to the bacteria colonizing the gingival crevice. Periodontitis has been associated with several other diseases, most prominently diabetes. The relation between periodontitis and diabetes is bidirectional in the sense that diabetes increases the risk for periodontitis and vice versa. Periodontitis also increases the risk for cardiovascular disease and cancer.
    MeSH term(s) Humans ; Risk Factors ; Periodontitis ; Cardiovascular Diseases ; Sweden ; Diabetes Mellitus
    Language Swedish
    Publishing date 2024-03-13
    Publishing country Sweden
    Document type English Abstract ; Journal Article
    ZDB-ID 391010-6
    ISSN 1652-7518 ; 0023-7205
    ISSN (online) 1652-7518
    ISSN 0023-7205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.411: Show issues Location:
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  6. Article ; Online: Diabetes och parodontit – viktig aspekt av diabetesvården.

    Norhammar, Anna / Gustafsson, Anders / Rydén, Lars / Brismar, Kerstin

    Lakartidningen

    2024  Volume 121

    Abstract: Diabetes and periodontitis are two global epidemics. There is a two-way relationship between diabetes and periodontitis. Diabetes increases the risk of periodontitis and periodontitis increases the risk for deteriorating glucose levels, having undetected ...

    Title translation Diabetes and periodontitis - common, important but often neglected.
    Abstract Diabetes and periodontitis are two global epidemics. There is a two-way relationship between diabetes and periodontitis. Diabetes increases the risk of periodontitis and periodontitis increases the risk for deteriorating glucose levels, having undetected diabetes, and for future diabetes. A recent Cochrane report summarized that there is moderate-certainty evidence that periodontal treatment improves glycaemic control in people with both periodontitis and diabetes. The recent PAROKRANK study found that undetected dysglycaemia was independently associated to both myocardial infarction and to periodontitis. To increase awareness of oral health in people with diabetes this article summarizes recent evidence.
    MeSH term(s) Humans ; Diabetes Mellitus ; Myocardial Infarction ; Periodontitis
    Language Swedish
    Publishing date 2024-03-13
    Publishing country Sweden
    Document type English Abstract ; Journal Article
    ZDB-ID 391010-6
    ISSN 1652-7518 ; 0023-7205
    ISSN (online) 1652-7518
    ISSN 0023-7205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.411: Show issues Location:
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  7. Article ; Online: Transcriptional signatures measured in whole blood correlate with protection against tuberculosis in inbred and outbred mice.

    Kurtz, Sherry L / Rydén, Patrik / Elkins, Karen L

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0289358

    Abstract: Although BCG has been used for almost 100 years to immunize against Mycobacterium tuberculosis, TB remains a global public health threat. Numerous clinical trials are underway studying novel vaccine candidates and strategies to improve or replace BCG, ... ...

    Abstract Although BCG has been used for almost 100 years to immunize against Mycobacterium tuberculosis, TB remains a global public health threat. Numerous clinical trials are underway studying novel vaccine candidates and strategies to improve or replace BCG, but vaccine development still lacks a well-defined set of immune correlates to predict vaccine-induced protection against tuberculosis. This study aimed to address this gap by examining transcriptional responses to BCG vaccination in C57BL/6 inbred mice, coupled with protection studies using Diversity Outbred mice. We evaluated relative gene expression in blood obtained from vaccinated mice, because blood is easily accessible, and data can be translated to human studies. We first determined that the average peak time after vaccination is 14 days for gene expression of a small subset of immune-related genes in inbred mice. We then performed global transcriptomic analyses using whole blood samples obtained two weeks after mice were vaccinated with BCG. Using comparative bioinformatic analyses and qRT-PCR validation, we developed a working correlate panel of 18 genes that were highly correlated with administration of BCG but not heat-killed BCG. We then tested this gene panel using BCG-vaccinated Diversity Outbred mice and revealed associations between the expression of a subset of genes and disease outcomes after aerosol challenge with M. tuberculosis. These data therefore demonstrate that blood-based transcriptional immune correlates measured within a few weeks after vaccination can be derived to predict protection against M. tuberculosis, even in outbred populations.
    MeSH term(s) Animals ; Humans ; Mice ; BCG Vaccine ; Collaborative Cross Mice ; Mice, Inbred C57BL ; Tuberculosis/microbiology ; Mycobacterium tuberculosis/genetics ; Vaccination
    Chemical Substances BCG Vaccine
    Language English
    Publishing date 2023-08-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0289358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: After Metformin - Next Steps for Type 2 Diabetes with Low Cardiovascular Risk.

    Rydén, Lars / Standl, Eberhard

    The New England journal of medicine

    2022  Volume 387, Issue 12, Page(s) 1136–1138

    MeSH term(s) Cardiometabolic Risk Factors ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Humans ; Hypoglycemic Agents/therapeutic use ; Metformin/therapeutic use ; Risk Factors
    Chemical Substances Hypoglycemic Agents ; Metformin (9100L32L2N)
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMe2210531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Risk prediction in patients with diabetes: is SCORE 2D the perfect solution?

    Rydén, Lars / Ferrannini, Giulia / Standl, Eberhard

    European heart journal

    2023  Volume 44, Issue 28, Page(s) 2557–2559

    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/drug therapy ; Risk Factors ; Cardiovascular Diseases ; Heart Disease Risk Factors ; Europe
    Language English
    Publishing date 2023-06-27
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: In vivo

    Polland, Linnea / Rydén, Hanna / Su, Yi / Paulsson, Magnus

    Microbiology spectrum

    2023  , Page(s) e0163923

    Abstract: Haemophilus ... ...

    Abstract Haemophilus influenzae
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.01639-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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