Article ; Online: Ecological studies of COVID-19 and air pollution: How useful are they?
Environmental epidemiology (Philadelphia, Pa.)
2022 Volume 6, Issue 1, Page(s) e195
Abstract: Background: Results from ecological studies have suggested that air pollution increases the risk of developing and dying from COVID-19. Drawing causal inferences from the measures of association reported in ecological studies is fraught with challenges ... ...
Abstract | Background: Results from ecological studies have suggested that air pollution increases the risk of developing and dying from COVID-19. Drawing causal inferences from the measures of association reported in ecological studies is fraught with challenges given biases arising from an outcome whose ascertainment is incomplete, varies by region, time, and across sociodemographic characteristics, and cannot account for clustering or within-area heterogeneity. Through a series of analyses, we illustrate the dangers of using ecological studies to assess whether ambient air pollution increases the risk of dying from, or transmitting, COVID-19. Methods: We performed an ecological analysis in the continental United States using county-level ambient concentrations of fine particulate matter (PM Results: Our analyses revealed that the shape of the exposure-response curve between PM Conclusions: Our analyses indicated that ecological analyses are prone to showing spurious relationships between ambient air pollution and mortality from COVID-19 as well as the prevalence of HIV. We discuss the many potential biases inherent in any ecological-based analysis of air pollution and COVID-19. |
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Language | English |
Publishing date | 2022-02-04 |
Publishing country | United States |
Document type | Journal Article |
ISSN | 2474-7882 |
ISSN (online) | 2474-7882 |
DOI | 10.1097/EE9.0000000000000195 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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