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  1. Book ; Online ; E-Book: Medical, Dental, and Wellness Tourism

    Swenson, Mary Schreiber / Bansal, Amit

    A Post-Pandemic Perspective

    (Advances in Hospitality and Tourism Series)

    2023  

    Abstract: A thorough guide to travel and tourism for treatment of health-related issues. It covers the benefits and challenges, the effect of COVID-19 on medical tourism, selecting the right destination and facility, ending your life in another country, birth ... ...

    Author's details Mary Schreiber Swenson and Amit Bansal
    Series title Advances in Hospitality and Tourism Series
    Abstract A thorough guide to travel and tourism for treatment of health-related issues. It covers the benefits and challenges, the effect of COVID-19 on medical tourism, selecting the right destination and facility, ending your life in another country, birth tourism, medical travel for second opinions, privacy and health data security, etc.
    Keywords Medical tourism ; Medical tourism/Technological innovations
    Subject code 362.10285
    Language English
    Dates of publication 2023-2024
    Size 1 online resource (308 pages)
    Edition First edition.
    Publisher Apple Academic Press Inc
    Publishing place Palm Bay, FL
    Document type Book ; Online ; E-Book
    Note Includes index.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-000-93684-8 ; 9781774914953 ; 978-1-000-93684-1 ; 1774914956
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Critique of a Study on Breast Ultrasound as an Adjunct to Breast Tomosynthesis for Breast Cancer Screening and Diagnosis.

    Bansal, Amit

    Ultrasound in medicine & biology

    2023  Volume 50, Issue 3, Page(s) 453

    MeSH term(s) Female ; Humans ; Breast Neoplasms/diagnostic imaging ; Early Detection of Cancer ; Breast/diagnostic imaging ; Mammography ; Ultrasonography, Mammary ; Mass Screening ; Breast Density
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Letter
    ZDB-ID 186150-5
    ISSN 1879-291X ; 0301-5629
    ISSN (online) 1879-291X
    ISSN 0301-5629
    DOI 10.1016/j.ultrasmedbio.2023.11.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: From rejection to the Nobel Prize: Karikó and Weissman's pioneering work on mRNA vaccines, and the need for diversity and inclusion in translational immunology.

    Bansal, Amit

    Frontiers in immunology

    2023  Volume 14, Page(s) 1306025

    Abstract: Katalin Karikó and Drew Weissman were given the 2023 Nobel Prize in Physiology or Medicine for their findings of nucleoside base modifications that lead to the development of effective mRNA vaccines against COVID-19. This was a remarkable achievement, ... ...

    Abstract Katalin Karikó and Drew Weissman were given the 2023 Nobel Prize in Physiology or Medicine for their findings of nucleoside base modifications that lead to the development of effective mRNA vaccines against COVID-19. This was a remarkable achievement, given that their initial manuscript was rejected by Nature and Science in 2005. The development of mRNA vaccines lagged for more than a decade for several reasons, including the lack of funding, the perceived risks of the technology, and the scepticism of many scientists. Furthermore, Karikó and Weissman's study appeared to be technical and difficult to understand. The COVID-19 pandemic, on the other hand, has shown the importance of mRNA vaccine technology. COVID-19 mRNA vaccines have been highly effective in preventing serious illness, hospitalization, and death. The Nobel Prize for Karikó and Weissman highlights the importance of perseverance, diversity, and inclusion in translational immunology. We need to build a more inclusive scientific community, where scientists from all backgrounds are supported and their work is valued. This will result in more scientific breakthroughs and better healthcare for everyone.
    MeSH term(s) Humans ; COVID-19 Vaccines ; Nobel Prize ; Pandemics ; COVID-19/prevention & control ; Cultural Diversity
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-11-08
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1306025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cardiovascular positron emission tomography: established and emerging role in cardiovascular diseases.

    Bansal, Amit / Ananthasubramaniam, Karthikeyan

    Heart failure reviews

    2022  Volume 28, Issue 2, Page(s) 387–405

    Abstract: Cardiac positron emission tomography (PET) imaging has established themselves firmly as excellent and reliable functional imaging modalities in assessment of the spectrum of coronary artery disease. With the explosion of technology advances and the dream ...

    Abstract Cardiac positron emission tomography (PET) imaging has established themselves firmly as excellent and reliable functional imaging modalities in assessment of the spectrum of coronary artery disease. With the explosion of technology advances and the dream of flow quantification now a reality, the value of PET is now well realized. Cardiac PET has proved itself as precise imaging modality that provides functional imaging of the heart in addition to anatomical imaging. It has established itself as one of the best available techniques for evaluation of myocardial viability. Hybrid PET/computed tomography provides simultaneous integration of coronary anatomy and function with myocardial perfusion and metabolism, thereby improving characterization of the dysfunctional area and chronic coronary artery disease. The availability of quantitative myocardial blood flow evaluation with PET provides additional prognostic information and increases diagnostic accuracy in the management of patients with coronary artery disease. Hybrid imaging seems to hold immense potential in optimizing management of cardiovascular diseases and furthering clinical research.
    MeSH term(s) Humans ; Coronary Artery Disease ; Cardiovascular Diseases ; Myocardial Perfusion Imaging/methods ; Heart ; Positron-Emission Tomography/methods
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1336499-6
    ISSN 1573-7322 ; 1382-4147
    ISSN (online) 1573-7322
    ISSN 1382-4147
    DOI 10.1007/s10741-022-10270-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Hungry bone syndrome like presentation following single-dose denosumab for hypercalcaemia secondary to sarcoidosis with IgA nephropathy.

    Nachankar, Amit / Katyal, Amit / Bansal, Naresh / Bishnoi, Alka

    BMJ case reports

    2022  Volume 15, Issue 7

    Abstract: A woman in her mid-50s with IgA nephropathy, sarcoidosis and steroid-induced diabetes mellitus presented with generalised paraesthesia and spontaneous tetany. She had received denosumab 60 mg subcutaneously 8 weeks previously for parathyroid hormone ... ...

    Abstract A woman in her mid-50s with IgA nephropathy, sarcoidosis and steroid-induced diabetes mellitus presented with generalised paraesthesia and spontaneous tetany. She had received denosumab 60 mg subcutaneously 8 weeks previously for parathyroid hormone independent hypercalcaemia.At admission, she had severe hypocalcaemia (5 mg/dL), hypophosphataemia (1.9 mg/dL), hypomagnesaemia (1.4 mg/dL) and elevated serum creatinine (1.48 mg/dL) with prolonged QTc (corrected QT interval) on electrocardiograph. She initially received intravenous calcium and magnesium followed by oral calcium carbonate and calcitriol. Her prednisolone dose was tapered to 5 mg/day. Evaluation showed secondary hyperparathyroidism (1474 pg/mL) and elevated 1,25-dihydroxy vitamin D (195 pg/mL). After 1 week of oral calcium carbonate (3000 mg/day) and calcitriol (1.5 µg/day), she achieved normocalcaemia (8.1 mg/dL).To conclude, denosumab for hypercalcaemia with renal insufficiency causes prolonged severe symptomatic hypocalcaemia and hypophosphataemia mimicking hungry bone syndrome. It is important to periodically monitor for hypocalcaemia after denosumab.
    MeSH term(s) Bone Diseases, Metabolic/drug therapy ; Calcitriol/therapeutic use ; Calcium/therapeutic use ; Calcium Carbonate/therapeutic use ; Denosumab/adverse effects ; Female ; Glomerulonephritis, IGA/complications ; Humans ; Hypercalcemia/complications ; Hypercalcemia/etiology ; Hyperparathyroidism, Secondary/complications ; Hypocalcemia/chemically induced ; Hypocalcemia/complications ; Hypocalcemia/drug therapy ; Hypophosphatemia/complications ; Parathyroid Hormone ; Sarcoidosis/complications
    Chemical Substances Parathyroid Hormone ; Denosumab (4EQZ6YO2HI) ; Calcitriol (FXC9231JVH) ; Calcium Carbonate (H0G9379FGK) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2022-07-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2022-250647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Single Sequence Whole-Spine Screening Magnetic Resonance Imaging: Diagnostic and Therapeutic Role in Multiple-Level Spinal Tuberculosis.

    Sareen, Atul / Guha, Mayukh / Bansal, Kuldeep / Hegde, Amit / Boruah, Tankeswar

    Cureus

    2024  Volume 16, Issue 1, Page(s) e52757

    Abstract: Introduction: Spinal tuberculosis (TB) is the most common form of skeletal tuberculosis. Paradiscal continuous vertebral involvement at a single level is the most prevalent pattern among all forms of spinal TB. There is a wide range of reported ... ...

    Abstract Introduction: Spinal tuberculosis (TB) is the most common form of skeletal tuberculosis. Paradiscal continuous vertebral involvement at a single level is the most prevalent pattern among all forms of spinal TB. There is a wide range of reported incidences of multiple-level non-contiguous spinal TB in the literature. We would like to discuss on the utility of single whole spine screening T2-weighted (T2W) mid-sagittal magnetic resonance imaging (MRI) film in diagnosing multiple-level spinal TB and therapeutic benefits it can provide.
    Methods: We have done a retrospective review of the collected data of patients in Vardhman Mahavir Medical College and Safdarjung Hospital from August 2017 to October 2021 to find the incidence of multiple-level spinal TB and possible factors attributed to this specific disease pattern. All the patients who had been diagnosed of spinal TB either microbiologically or histopathologically or by a good clinical response to anti-tubercular treatment (ATT) and had a whole spine screening MRI film, were included. Patients of spinal TB who did not have a whole spine screening MRI were excluded from the study. Multiple-level spinal TB was diagnosed when lesions were identified in vertebral levels other than a typical paradiscal lesion, and additional lesions were separated from the primary disease by at least one normal spinal segment.
    Results: Among the patients, 242 met the inclusion criteria, and 76 showed multiple-level non-contiguous spinal TB on MRI, incidence being 31.4%. The rest of the 166 patients showed typical single-segment contiguous lesions. By doing multivariate analysis to determine the independent risk factors for multiple-level spinal TB, extremes of age (<20 years and >50 years) have been found to be a significant factor with p value of 0.0001. Though drug resistance was not found to be a significant risk factor (p value 0.051), the proportion of patients having multiple-level TB was far more in the drug-resistant group (13/76).
    Conclusions: Single sequence whole spine screening MRI film is an effective, economical, and time-saving tool to detect multiple-level spinal TB. Along with its diagnostic accuracy, it also provides therapeutic benefits like access to a more approachable site for biopsy.
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Small-molecule inhibitors of kinases in breast cancer therapy: recent advances, opportunities, and challenges.

    Bansal, Isha / Pandey, Amit Kumar / Ruwali, Munindra

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1244597

    Abstract: Breast cancer is the most common malignancy in women worldwide and despite significant advancements in detection, treatment, and management of cancer, it is still the leading cause of malignancy related deaths in women. Understanding the fundamental ... ...

    Abstract Breast cancer is the most common malignancy in women worldwide and despite significant advancements in detection, treatment, and management of cancer, it is still the leading cause of malignancy related deaths in women. Understanding the fundamental biology of breast cancer and creating fresh diagnostic and therapeutic strategies have gained renewed focus in recent studies. In the onset and spread of breast cancer, a group of enzymes known as kinases are extremely important. Small-molecule kinase inhibitors have become a promising class of medications for the treatment of breast cancer owing to their capacity to specifically target kinases involved in the growth and progression of cancer. The creation of targeted treatments that block these kinases and the signalling pathways that they activate has completely changed how breast cancer is treated. Many of these targeted treatments have been approved for the treatment of breast cancer as clinical trials have demonstrated their great efficacy. CDK4/6 inhibitors, like palbociclib, abemaciclib, and ribociclib, EGFR inhibitors such as gefitinib and erlotinib and HER2-targeting small-molecule kinases like neratinib and tucatinib are some examples that have shown potential in treating breast cancer. Yet, there are still difficulties in the development of targeted medicines for breast cancer, such as figuring out which patient subgroups may benefit from these therapies and dealing with drug resistance problems. Notwithstanding these difficulties, kinase-targeted treatments for breast cancer still have a lot of potential. The development of tailored medicines will continue to be fuelled by the identification of novel targets and biomarkers for breast cancer as a result of advancements in genomic and proteomic technology.
    Language English
    Publishing date 2023-08-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1244597
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: Controlling Learned Effects to Reduce Spurious Correlations in Text Classifiers

    Bansal, Parikshit / Sharma, Amit

    2023  

    Abstract: To address the problem of NLP classifiers learning spurious correlations between training features and target labels, a common approach is to make the model's predictions invariant to these features. However, this can be counter-productive when the ... ...

    Abstract To address the problem of NLP classifiers learning spurious correlations between training features and target labels, a common approach is to make the model's predictions invariant to these features. However, this can be counter-productive when the features have a non-zero causal effect on the target label and thus are important for prediction. Therefore, using methods from the causal inference literature, we propose an algorithm to regularize the learnt effect of the features on the model's prediction to the estimated effect of feature on label. This results in an automated augmentation method that leverages the estimated effect of a feature to appropriately change the labels for new augmented inputs. On toxicity and IMDB review datasets, the proposed algorithm minimises spurious correlations and improves the minority group (i.e., samples breaking spurious correlations) accuracy, while also improving the total accuracy compared to standard training.

    Comment: Accepted to ACL 2023
    Keywords Computer Science - Machine Learning ; Computer Science - Computation and Language
    Subject code 006
    Publishing date 2023-05-26
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Book ; Online: Large Language Models as Annotators

    Bansal, Parikshit / Sharma, Amit

    Enhancing Generalization of NLP Models at Minimal Cost

    2023  

    Abstract: State-of-the-art supervised NLP models achieve high accuracy but are also susceptible to failures on inputs from low-data regimes, such as domains that are not represented in training data. As an approximation to collecting ground-truth labels for the ... ...

    Abstract State-of-the-art supervised NLP models achieve high accuracy but are also susceptible to failures on inputs from low-data regimes, such as domains that are not represented in training data. As an approximation to collecting ground-truth labels for the specific domain, we study the use of large language models (LLMs) for annotating inputs and improving the generalization of NLP models. Specifically, given a budget for LLM annotations, we present an algorithm for sampling the most informative inputs to annotate and retrain the NLP model. We find that popular active learning strategies such as uncertainty-based sampling do not work well. Instead, we propose a sampling strategy based on the difference in prediction scores between the base model and the finetuned NLP model, utilizing the fact that most NLP models are finetuned from a base model. Experiments with classification (semantic similarity) and ranking (semantic search) tasks show that our sampling strategy leads to significant gains in accuracy for both the training and target domains.
    Keywords Computer Science - Computation and Language ; Computer Science - Machine Learning
    Subject code 006
    Publishing date 2023-06-27
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Re: Utility of Routine Preoperative

    Bansal, Amit / Kumar, Anant

    The Journal of urology

    2020  Volume 205, Issue 2, Page(s) 336–337

    MeSH term(s) Cystectomy ; Fluorodeoxyglucose F18 ; Humans ; Lymphatic Metastasis ; Positron-Emission Tomography ; Tomography, X-Ray Computed
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2020-10-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000001409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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