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Article ; Online: Modulation of starch structure, swallowability and digestibility of 3D-printed diabetic-friendly food for the elderly by dry heating.

Huang, Jinjin / Zhang, Min / Mujumdar, Arun S / Li, Chunli

International journal of biological macromolecules

2024 Volume 264, Issue Pt 2, Page(s) 130629

Abstract: ... improved printability and self-support compared to the control. B45 (white quinoa, dry heating for 45 min ... and C45 (brown rice, dry heating for 45 min) had significant elasticity and greater internal ...

Abstract	Elderly people often experience difficulty in swallowing and have impaired regulation of the nervous system. Furthermore, their blood glucose level can rise easily after eating. Therefore, functional foods that are easy to swallow and can maintain blood glucose at a lower level have been an important research topic in recent years. In this study, 3D printing was combined with dry heating to modify the starch in white quinoa and brown rice to develop whole grain foods with Osmanthus flavor that meet the dietary habits of the elderly. The samples were tested for printability, swallowing performance, and in vitro digestion. The results showed that after dry heating, all samples had shear-thinning properties and could pass through the extrusion nozzle of the printer smoothly. Both white quinoa and brown rice showed improved printability and self-support compared to the control. B45 (white quinoa, dry heating for 45 min) and C45 (brown rice, dry heating for 45 min) had significant elasticity and greater internal interaction strength during swallowing to resist disintegration of food particles during chewing. B45, C30, and C45, conformed to class 4 consistency and were characterized by easy swallowing of the diet. Further, dry heating resulted in greater resistance to enzymatic degradation of white quinoa and brown rice starch, with overall in vitro digestibility lower than the control.
MeSH term(s)	Humans ; Aged ; Starch/chemistry ; Blood Glucose/metabolism ; Heating ; Digestion ; Diabetes Mellitus ; Printing, Three-Dimensional ; Oryza/chemistry
Chemical Substances	Starch (9005-25-8) ; Blood Glucose
Language	English
Publishing date	2024-03-05
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.130629
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Article ; Online: Application of ultrafiltration technology in drinking water industry of China

Jinjin Jia / Min Rui / Xiaoxiang Cheng / Heng Liang

Aqua, Vol 72, Iss 12, Pp 2408-

A comprehensive assessment of hybrid membrane processes

2023 Volume 2421

Abstract: Over the last decades, ultrafiltration (UF) has been and will continue to play an important role in the Chinese drinking water industry. The hybrid membrane processes have been emerging as promising alternatives to traditional treatment processes. This ... ...

Abstract	Over the last decades, ultrafiltration (UF) has been and will continue to play an important role in the Chinese drinking water industry. The hybrid membrane processes have been emerging as promising alternatives to traditional treatment processes. This review paper offers a thorough overview of the current status of UF technology in the drinking water industry in China, while also evaluating the landscape of different hybrid membrane processes. The paper conducts statistical analysis on the projects operational between 2004 and 2022; and those currently under construction. This analysis accentuates the evolution of scale and capacity, geographical distribution characteristics, and the driving forces. Furthermore, the characteristics and application scenarios of several hybrid membrane processes are emphatically described, including direct UF, gravity-driven membrane process, coagulation-UF, activated carbon-UF, medium-flow process, long-flow process, and double-membrane process. A granular dissection of UF membrane market distribution follows, including an incisive comparison between submerged and pressurized UF membrane systems. Finally, the potential trajectory of UF in the Chinese drinking water industry is prospected. UF applications have grown significantly in China's drinking water industry, with the dominance of medium- and long-flow membrane processes. UF technology will contribute to future decentralized water supply. HIGHLIGHTS The development of UF full-scale applications in drinking water treatment in China is revisited.; The review provides the geographic distribution of UF DWTPs and driving forces.; The characteristics and application scenarios of four hybrid membrane processes are described.; The UF membrane market distribution is identified.; The insights for the future application of UF technology are highlighted.;
Keywords	drinking water treatment ; full-scale application ; hybrid membrane processes ; market distribution ; ultrafiltration ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350
Subject code	660
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	IWA Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Perspectives on Novel Technologies of Processing and Monitoring the Safety and Quality of Prepared Food Products.

Huang, Jinjin / Zhang, Min / Fang, Zhongxiang

Foods (Basel, Switzerland)

2023 Volume 12, Issue 16

Abstract: With the changes of lifestyles and rapid growth of prepared food industry, prepared fried rice that meets the consumption patterns of contemporary young people has become popular in China. Although prepared fried rice is convenient and nutritious, it has ...

Abstract	With the changes of lifestyles and rapid growth of prepared food industry, prepared fried rice that meets the consumption patterns of contemporary young people has become popular in China. Although prepared fried rice is convenient and nutritious, it has the following concerns in the supply chain: (1) susceptible to contamination by microorganisms; (2) rich in starch and prone to stall; and (3) vegetables in the ingredients have the issues of water loss and discoloration, and meat substances are vulnerable to oxidation and deterioration. As different ingredients are used in prepared fried rice, their food processing and quality monitoring techniques are also different. This paper reviews the key factors that cause changes in the quality of prepared fried rice, and the advantages and limitations of technologies in the processing and monitoring processes. The processing technologies for prepared fried rice include irradiation, high-voltage electric field, microwave, radio frequency, and ohmic heating, while the quality monitoring technologies include Raman spectral imaging, near-infrared spectral imaging, and low-field nuclear magnetic resonance technology. These technologies will serve as the foundation for enhancing the quality and safety of prepared fried rice and are essential to the further development of prepared fried rice in the emerging market.
Language	English
Publishing date	2023-08-15
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12163052
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Article: Case report: Application of targeted NGS for the detection of non-canonical driver variants in MPN.

Zhang, Jin / Shen, Kefeng / Xiao, Min / Huang, Jinjin / Wang, Jin / Wang, Yaqin / Hong, Zhenya

Frontiers in genetics

2023 Volume 14, Page(s) 1198834

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2023-06-16
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2023.1198834
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Article ; Online: Perspectives on Novel Technologies of Processing and Monitoring the Safety and Quality of Prepared Food Products

Huang, Jinjin / Zhang, Min / Fang, Zhongxiang

Foods. 2023 Aug. 15, v. 12, no. 16

2023

Abstract	With the changes of lifestyles and rapid growth of prepared food industry, prepared fried rice that meets the consumption patterns of contemporary young people has become popular in China. Although prepared fried rice is convenient and nutritious, it has the following concerns in the supply chain: (1) susceptible to contamination by microorganisms; (2) rich in starch and prone to stall; and (3) vegetables in the ingredients have the issues of water loss and discoloration, and meat substances are vulnerable to oxidation and deterioration. As different ingredients are used in prepared fried rice, their food processing and quality monitoring techniques are also different. This paper reviews the key factors that cause changes in the quality of prepared fried rice, and the advantages and limitations of technologies in the processing and monitoring processes. The processing technologies for prepared fried rice include irradiation, high-voltage electric field, microwave, radio frequency, and ohmic heating, while the quality monitoring technologies include Raman spectral imaging, near-infrared spectral imaging, and low-field nuclear magnetic resonance technology. These technologies will serve as the foundation for enhancing the quality and safety of prepared fried rice and are essential to the further development of prepared fried rice in the emerging market.
Keywords	discoloration ; electric field ; food industry ; irradiation ; meat ; nuclear magnetic resonance spectroscopy ; ohmic heating ; oxidation ; prepared foods ; radio waves ; rice ; starch ; supply chain ; China
Language	English
Dates of publication	2023-0815
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12163052
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Selective enhancement of fear extinction by inhibiting neuronal adenylyl cyclase 1 (AC1) in aged mice.

Shi, Wantong / Chen, Qi-Yu / Ma, Yujie / Wan, Jinjin / Li, Xu-Hui / Zhuo, Min

Molecular brain

2024 Volume 17, Issue 1, Page(s) 11

Abstract: Adenylyl cyclase 1 (AC1) is a selective subtype of ACs, which is selectively expressed in neurons. The activation of AC1 is activity-dependent, and AC1 plays an important role in cortical excitation that contributes to chronic pain and related emotional ... ...

Abstract	Adenylyl cyclase 1 (AC1) is a selective subtype of ACs, which is selectively expressed in neurons. The activation of AC1 is activity-dependent, and AC1 plays an important role in cortical excitation that contributes to chronic pain and related emotional disorders. Previous studies have reported that human-used NB001 (hNB001, a selective AC1 inhibitor) produced analgesic effects in different animal models of chronic pain. However, the potential effects of hNB001 on learning and memory have been less investigated. In the present study, we found that hNB001 affected neither the induction nor the expression of trace fear, but selectively enhanced the relearning ability during the extinction in aged mice. By contrast, the same application of hNB001 did not affect recent, remote auditory fear memory, or remote fear extinction in either adult or aged mice. Furthermore, a single or consecutive 30-day oral administration of hNB001 did not affect acute nociceptive response, motor function, or anxiety-like behavior in either adult or aged mice. Our results are consistent with previous findings that inhibition of AC1 did not affect general sensory, emotional, and motor functions in adult mice, and provide strong evidence that inhibiting the activity of AC1 may be beneficial for certain forms of learning and memory in aged mice.
MeSH term(s)	Humans ; Mice ; Animals ; Fear/physiology ; Chronic Pain ; Extinction, Psychological ; Adenylyl Cyclases/metabolism ; Neurons/metabolism
Chemical Substances	adenylyl cyclase 1 (EC 4.6.1.1) ; Adenylyl Cyclases (EC 4.6.1.1)
Language	English
Publishing date	2024-02-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2436057-0
ISSN	1756-6606 ; 1756-6606
ISSN (online)	1756-6606
ISSN	1756-6606
DOI	10.1186/s13041-024-01083-9
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Article ; Online: Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice

Shibin Ding / Jinjin Jiang / Guofu Zhang / Min Yu / Yang Zheng

Ecotoxicology and Environmental Safety, Vol 256, Iss , Pp 114897- (2023)

2023

Abstract: Background: Chronic ethanol ingestion causes persistent oxidative stresses in the liver, leading to hepatic injury and fibrosis, but the underlying mechanisms remain unclear. Recently, ambient particulate matter (PM) has been confirmed to aggravate high- ... ...

Abstract	Background: Chronic ethanol ingestion causes persistent oxidative stresses in the liver, leading to hepatic injury and fibrosis, but the underlying mechanisms remain unclear. Recently, ambient particulate matter (PM) has been confirmed to aggravate high-fat diet-induced liver fibrosis by enhancing oxidative stress. Thus, we hypothesized that oxidative stress induced by ambient PM exposure increases the severity of liver fibrosis caused by ethanol ingestion. Methods and results: C57BL/6 mice were subjected to ambient PM inhalation, ethanol ingestion or ambient PM-plus-ethanol ingestion for 12 weeks. Oxidative stress, mitochondrial reactive oxygen species (MtROS), liver fibrosis and ferroptosis indicators in the liver were evaluated. In vitro, oxidative stress, MtROS, ferroptosis indicators, profibrotic molecules and fibrosis markers in hepatic stellate (LX-2) cells were also determined. We found that ethanol ingestion markedly elevated hepatic oxidative stress and MtROS levels, triggered hepatic ferroptosis, and induced liver fibrosis, along with upregulation of the profibrotic molecule TGF-β1 and fibrosis marker collagen-I, in mice. Moreover, the combination of ambient PM and ethanol accelerated these adverse effects. Importantly, the combination of PM exposure and ethanol ingestion had a synergistic effect on these changes. In vitro, LX-2 cells activated with PM2.5 alone or combined with ethanol showed upregulation of TGF-β1 and collagen-I. In addition, the levels of MtROS, the oxidative stress marker 4-hydroxynonenal (4-HNE) and ferroptosis-related proteins and the GSH/GSSG ratio were significantly increased in PM2.5 plus ethanol-treated LX-2 cells. After pretreatment with a MtROS scavenger (Mito-TEMPO), we found that Mito-TEMPO treatment inhibited ferroptosis and oxidative stress in PM2.5 plus ethanol-treated LX-2 cells. Furthermore, a speciﬁc ferroptosis inhibitor (Fer-1) decreased the levels of ferroptosis-related proteins and profibrotic molecules in activated LX-2 cells co-exposed to PM2.5 and ethanol. ...
Keywords	Particulate matter ; Ethanol ; Mitochondrial reactive oxygen species ; Oxidative stress ; Ferroptosis ; Hepatic fibrosis ; Environmental pollution ; TD172-193.5 ; Environmental sciences ; GE1-350
Subject code	610
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A new perspective on mesenchymal stem cell-based therapy for liver diseases: restoring mitochondrial function.

Cen, Yelei / Lou, Guohua / Qi, Jinjin / Zheng, Min / Liu, Yanning

Cell communication and signaling : CCS

2023 Volume 21, Issue 1, Page(s) 214

Abstract: Mesenchymal stem cells (MSCs) have emerged as a promising alternative treatment for liver disease due to their roles in regeneration, fibrosis inhibition, and immunoregulation. Mitochondria are crucial in maintaining hepatocyte integrity and function. ... ...

Abstract	Mesenchymal stem cells (MSCs) have emerged as a promising alternative treatment for liver disease due to their roles in regeneration, fibrosis inhibition, and immunoregulation. Mitochondria are crucial in maintaining hepatocyte integrity and function. Mitochondrial dysfunction, such as impaired synthesis of adenosine triphosphate (ATP), decreased activity of respiratory chain complexes, and altered mitochondrial dynamics, is observed in most liver diseases. Accumulating evidence has substantiated that the therapeutic potential of MSCs is mediated not only through their cell replacement and paracrine effects but also through their regulation of mitochondrial dysfunction in liver disease. Here, we comprehensively review the involvement of mitochondrial dysfunction in the development of liver disease and how MSCs can target mitochondrial dysfunction. We also discuss recent advances in a novel method that modifies MSCs to enhance their functions in liver disease. A full understanding of MSC restoration of mitochondrial function and the underlying mechanisms will provide innovative strategies for clinical applications. Video Abstract.
MeSH term(s)	Humans ; Liver Diseases/therapy ; Mitochondria ; Mitochondrial Membranes ; Adenosine Triphosphate ; Mesenchymal Stem Cells
Chemical Substances	Adenosine Triphosphate (8L70Q75FXE)
Language	English
Publishing date	2023-08-18
Publishing country	England
Document type	Video-Audio Media ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2126315-2
ISSN	1478-811X ; 1478-811X
ISSN (online)	1478-811X
ISSN	1478-811X
DOI	10.1186/s12964-023-01230-0
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Article ; Online: Technological innovations enhance postharvest fresh food resilience from a supply chain perspective.

Huang, Jinjin / Zhang, Min / Mujumdar, Arun S / Ma, Yamei

Critical reviews in food science and nutrition

2023 , Page(s) 1–23

Abstract: Fresh food is rich in nutrients but is usually seasonal, perishable, and challenging to store without degradation of quality. The inherent limitations of various preservation technologies can result in losses in all stages of the supply chain. As ... ...

Abstract	Fresh food is rich in nutrients but is usually seasonal, perishable, and challenging to store without degradation of quality. The inherent limitations of various preservation technologies can result in losses in all stages of the supply chain. As consumers of fresh foods have become more health-conscious, new technologies for intelligent, energy-efficient, and nondestructive preservation and processing have emerged as a research priority in recent years. This review aims to summarize the quality change characteristics of postharvest fruits, vegetables, meats, and aquatic products. It critically analyzes research progress and applications of various emerging technologies, which include: the application of high-voltage electric field, magnetic field, electromagnetic field, plasma, electrolytic water, nanotechnology, modified atmosphere packaging, and composite bio-coated film preservation technologies. An evaluation is presented of the benefits and drawbacks of these technologies, as well as future development trends. Moreover, this review provides guidance for design of the food supply chain to take advantage of various technologies used to process food, reduce losses and waste of fresh food, and this improve the overall resilience of the supply chain.
Language	English
Publishing date	2023-07-06
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1037504-1
ISSN	1549-7852 ; 1040-8398
ISSN (online)	1549-7852
ISSN	1040-8398
DOI	10.1080/10408398.2023.2232464
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Article ; Online: MicroRNA let-7g links foam cell formation and adipogenic differentiation: A key regulator of Paeonol treating atherosclerosis-osteoporosis.

Yan, Jinjin / Yang, Yulong / Liu, Yarong / Shi, Xiaoyan / Wu, Hongfei / Dai, Min

Phytomedicine : international journal of phytotherapy and phytopharmacology

2024 Volume 126, Page(s) 155447

Abstract: Backgroud: High comorbidity rates have been reported in patients with atherosclerosis and osteoporosis, posing a serious risk to the health and well-being of elderly patients. To improve and update clinical practice regarding the joint treatment of ... ...

Abstract	Backgroud: High comorbidity rates have been reported in patients with atherosclerosis and osteoporosis, posing a serious risk to the health and well-being of elderly patients. To improve and update clinical practice regarding the joint treatment of these two diseases, the common mechanisms of atherosclerosis and osteoporosis need to be clarified. MicroRNAs (miRNAs), are importance molecules in the pathogenesis of human diseases, including in cardiovascular and orthopedic fields. They have garnered interest as potential targets for novel therapeutic strategies. However, the key miRNAs involved in atherosclerosis and osteoporosis and their precise regulation mechanisms remain unknown. Paeonol (Pae), an active ingredient in Cortex Moutan, has shown promising results in improving both lipid and bone metabolic abnormalities. However, it is uncertain whether this agent can exert a cotherapeutic effect on atherosclerosis and osteoporosis. Objective: This study aimed to screen important shared miRNAs in atherosclerotic and osteoporotic complications, and explore the mechanism of the protective effects of Pae against atherosclerosis and osteoporosis in high-fat diet (HFD)-fed ApoE Methods: An experimental atherosclerosis and osteoporosis model was established in 40-week-old HFD ApoE Results: miR let-7g identified using bioinformatics was assessed to evaluate its participation in atherosclerosis-osteoporosis. Experimental analysis showed reduced miR let-7g levels in the atherosclerosis-osteoporosis mice model. Moreover, miR let-7g was required for BMSC - Raw 264.7 cell crosstalk, thereby promoting foam cell formation and adipocyte differentiation. Treatment with Pae significantly reduced plaque accumulation and foam cell number in the aorta while increasing bone density and improving trabecular bone microarchitecture in HFD ApoE Conclusion: The study results suggested that miR let-7g participates in atherosclerosis -osteoporosis regulation and that Pae acts as a potential therapeutic agent for preventing atherosclerosis-osteoporosis through regulatory effects on the miR let-7g/HMGA2/CEBPβ pathway to hinder foam cell formation and adipocyte differentiation.
MeSH term(s)	Humans ; Animals ; Mice ; Aged ; Foam Cells ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Atherosclerosis/drug therapy ; Atherosclerosis/metabolism ; Cell Differentiation ; Osteoporosis/drug therapy ; Osteoporosis/metabolism ; Apolipoproteins E/genetics ; Acetophenones
Chemical Substances	paeonol (3R834EPI82) ; MicroRNAs ; Apolipoproteins E ; Acetophenones
Language	English
Publishing date	2024-02-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2024.155447
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